4TSZA

Crystal structure of dna polymerase sliding clamp from pseudomonas aeruginosa with ligand
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
368
structure length
363
Chain Sequence
HMHFTIQREALLKPLQLVAGVVEQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLEDAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPEGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMCSLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAYVVMPMRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
pubmed doi rcsb
molecule tags Transferase
source organism Pseudomonas aeruginosa
molecule keywords DNA polymerase III subunit beta
total genus 95
structure length 363
sequence length 368
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tszA02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tszA03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tszA01
4K3KA 4K3SA 4PNUA 3QSBA 3BEPA 4K3PA 3T0PA 2XURA 1JQJA 4TR6A 5FVEA 4MJRA 3QSBB 4N97A 4PNWA 3D1EA 3PGEB 3D1GA 1UNNA 2AWAA 4OVFA 5AH2A 5AGUA 4PNVA 3L0WA 3Q4LA 4TR8A 1VPKA 5AGVA 4N96A 4TRTA 4S3IA 2AVTA 3PWEA 3L10A 3Q4JA 3D1FA 3P16A 4N99A 5FRQA 3Q4KA 4N9AA 4MJQA 1MMIA 5AH4A 4MJPA 4K3MA 4TSZA 4N95A 4K3LA 4OVHA 4TR7A 3RB9A 3F1VA 1JQLA 1OK7A 4K3OA 4K74A 2POLA 4N98A 4N94A 4K3RA 4K3QA 4RKIA 4OVGA 3L0XA
chains in the Genus database with same CATH superfamily
4K3KA 4K3SA 4PNUA 3QSBA 3BEPA 4K3PA 3T0PA 2XURA 1JQJA 3L0XB 4TR6A 3PGEA 5FVEA 4MJRA 3QSBB 4N97A 4PNWA 3D1EA 3PGEB 3D1GA 1UNNA 2AWAA 4OVFA 5AH2A 5AGUA 4PNVA 3L0WA 3Q4LA 4TR8A 1VPKA 5AGVA 4N96A 3L0WB 4TRTA 4S3IA 2AVTA 3PWEA 3L10A 3Q4JA 3D1FA 3P16A 4N99A 3L10B 5FRQA 3Q4KA 4N9AA 4MJQA 1MMIA 5AH4A 4MJPA 4K3MA 4TSZA 4N95A 4K3LA 4OVHA 4TR7A 3RB9A 3F1VA 1JQLA 1OK7A 4K3OA 4K74A 2POLA 4N98A 4N94A 4K3RA 4K3QA 4RKIA 4OVGA 3L0XA
chains in the Genus database with same CATH topology
4K3KA 4K3SA 4PNUA 3QSBA 3BEPA 4K3PA 3T0PA 2XURA 1JQJA 4TR6A 5FVEA 4MJRA 3QSBB 4N97A 4PNWA 3D1EA 3PGEB 3D1GA 1UNNA 2AWAA 4OVFA 5AH2A 5AGUA 4PNVA 3L0WA 3Q4LA 4TR8A 1VPKA 5AGVA 4N96A 4TRTA 4S3IA 2AVTA 3PWEA 3L10A 3Q4JA 3D1FA 3P16A 4N99A 5FRQA 3Q4KA 4N9AA 4MJQA 1MMIA 5AH4A 4MJPA 4K3MA 4TSZA 4N95A 4K3LA 4OVHA 4TR7A 3RB9A 3F1VA 1JQLA 1OK7A 4K3OA 4K74A 2POLA 4N98A 4N94A 4K3RA 4K3QA 4RKIA 4OVGA 3L0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K3K A;  4K3S A;  4PNU A;  3QSB A;  3BEP A;  4K3P A;  3T0P A;  2XUR A;  1JQJ A;  4TR6 A;  5FVE A;  4MJR A;  3QSB B;  4N97 A;  4PNW A;  3D1E A;  3PGE B;  3D1G A;  1UNN A;  2AWA A;  4OVF A;  5AH2 A;  5AGU A;  4PNV A;  3L0W A;  3Q4L A;  4TR8 A;  1VPK A;  5AGV A;  4N96 A;  4TRT A;  4S3I A;  2AVT A;  3PWE A;  3L10 A;  3Q4J A;  3D1F A;  3P16 A;  4N99 A;  5FRQ A;  3Q4K A;  4N9A A;  4MJQ A;  1MMI A;  5AH4 A;  4MJP A;  4K3M A;  4TSZ A;  4N95 A;  4K3L A;  4OVH A;  4TR7 A;  3RB9 A;  3F1V A;  1JQL A;  1OK7 A;  4K3O A;  4K74 A;  2POL A;  4N98 A;  4N94 A;  4K3R A;  4K3Q A;  4RKI A;  4OVG A;  3L0X A; 
#chains in the Genus database with same CATH topology
 4K3K A;  4K3S A;  4PNU A;  3QSB A;  3BEP A;  4K3P A;  3T0P A;  2XUR A;  1JQJ A;  3L0X B;  4TR6 A;  3PGE A;  5FVE A;  4MJR A;  3QSB B;  4N97 A;  4PNW A;  3D1E A;  3PGE B;  3D1G A;  1UNN A;  2AWA A;  4OVF A;  5AH2 A;  5AGU A;  4PNV A;  3L0W A;  3Q4L A;  4TR8 A;  1VPK A;  5AGV A;  4N96 A;  3L0W B;  4TRT A;  4S3I A;  2AVT A;  3PWE A;  3L10 A;  3Q4J A;  3D1F A;  3P16 A;  4N99 A;  3L10 B;  5FRQ A;  3Q4K A;  4N9A A;  4MJQ A;  1MMI A;  5AH4 A;  4MJP A;  4K3M A;  4TSZ A;  4N95 A;  4K3L A;  4OVH A;  4TR7 A;  3RB9 A;  3F1V A;  1JQL A;  1OK7 A;  4K3O A;  4K74 A;  2POL A;  4N98 A;  4N94 A;  4K3R A;  4K3Q A;  4RKI A;  4OVG A;  3L0X A; 
#chains in the Genus database with same CATH homology
 4K3K A;  4K3S A;  4PNU A;  3QSB A;  3BEP A;  4K3P A;  3T0P A;  2XUR A;  1JQJ A;  4TR6 A;  5FVE A;  4MJR A;  3QSB B;  4N97 A;  4PNW A;  3D1E A;  3PGE B;  3D1G A;  1UNN A;  2AWA A;  4OVF A;  5AH2 A;  5AGU A;  4PNV A;  3L0W A;  3Q4L A;  4TR8 A;  1VPK A;  5AGV A;  4N96 A;  4TRT A;  4S3I A;  2AVT A;  3PWE A;  3L10 A;  3Q4J A;  3D1F A;  3P16 A;  4N99 A;  5FRQ A;  3Q4K A;  4N9A A;  4MJQ A;  1MMI A;  5AH4 A;  4MJP A;  4K3M A;  4TSZ A;  4N95 A;  4K3L A;  4OVH A;  4TR7 A;  3RB9 A;  3F1V A;  1JQL A;  1OK7 A;  4K3O A;  4K74 A;  2POL A;  4N98 A;  4N94 A;  4K3R A;  4K3Q A;  4RKI A;  4OVG A;  3L0X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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