4WB2A

Crystal structure of the mirror-image l-rna/l-dna aptamer nox-d20 in complex with mouse c5a complement anaphylatoxin
Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
69
structure length
69
Chain Sequence
ANLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPLCIRAFNECCTIANKIRKES

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Dna-rna hybrid
source organism Mus musculus
publication title Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
pubmed doi rcsb
molecule keywords Complement C5
total genus 27
structure length 69
sequence length 69
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4wb2A00
4UU9C 1KJSA 5B4PB 3CU7A 2A73B 4FXKB 5JPNB 4I6OA 1C5AA 4WB3A 4HWJA 3KLSA 4P3AA 4P39A 1CFAA 3HQBA 2B39A 4WB2A 3HQAA 4P3BA 4HW5A
chains in the Genus database with same CATH superfamily
4UU9C 4PUSA 1KJSA 5B4PB 1EA3A 3MD2A 3CU7A 2A73B 5CQEA 3VDXA 4FXKB 5JPNB 4I6OA 4ITVA 4D9JA 1C5AA 4WB3A 4HWJA 3KLSA 4P3AA 4P39A 1CFAA 4IQ4A 3HQBA 1AA7A 2B39A 4FXGB 3HQAA 4WB2A 4P3BA 5JPMB 2Z16A 4HW5A
chains in the Genus database with same CATH topology
4UU9C 1KJSA 5B4PB 3CU7A 2A73B 4FXKB 5JPNB 4I6OA 1C5AA 4WB3A 4HWJA 3KLSA 4P3AA 4P39A 1CFAA 3HQBA 2B39A 4WB2A 3HQAA 4P3BA 4HW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UU9 C;  1KJS A;  5B4P B;  3CU7 A;  2A73 B;  4FXK B;  5JPN B;  4I6O A;  1C5A A;  4WB3 A;  4HWJ A;  3KLS A;  4P3A A;  4P39 A;  1CFA A;  3HQB A;  2B39 A;  4WB2 A;  3HQA A;  4P3B A;  4HW5 A; 
#chains in the Genus database with same CATH topology
 4UU9 C;  4PUS A;  1KJS A;  5B4P B;  1EA3 A;  3MD2 A;  3CU7 A;  2A73 B;  5CQE A;  3VDX A;  4FXK B;  5JPN B;  4I6O A;  4ITV A;  4D9J A;  1C5A A;  4WB3 A;  4HWJ A;  3KLS A;  4P3A A;  4P39 A;  1CFA A;  4IQ4 A;  3HQB A;  1AA7 A;  2B39 A;  4FXG B;  3HQA A;  4WB2 A;  4P3B A;  5JPM B;  2Z16 A;  4HW5 A; 
#chains in the Genus database with same CATH homology
 4UU9 C;  1KJS A;  5B4P B;  3CU7 A;  2A73 B;  4FXK B;  5JPN B;  4I6O A;  1C5A A;  4WB3 A;  4HWJ A;  3KLS A;  4P3A A;  4P39 A;  1CFA A;  3HQB A;  2B39 A;  4WB2 A;  3HQA A;  4P3B A;  4HW5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

Application loaded.