4WB3A

Crystal structure of the mirror-image l-rna/l-dna aptamer nox-d20 in complex with mouse c5a-desarg complement anaphylatoxin
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
68
structure length
68
Chain Sequence
NLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPLCIRAFNECCTIANKIRKES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
pubmed doi rcsb
molecule tags Dna-rna hybrid
source organism Mus musculus
molecule keywords Complement C5
total genus 26
structure length 68
sequence length 68
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4wb3A00
4WB2A 5JPNB 4I6OA 1C5AA 3CU7A 4P3AA 1CFAA 3KLSA 4UU9C 1KJSA 4HW5A 3HQBA 2B39A 3HQAA 5B4PB 4HWJA 4P39A 2A73B 4WB3A 4FXKB 4P3BA
chains in the Genus database with same CATH superfamily
4WB2A 4IQ4A 5JPNB 4I6OA 1C5AA 4FXGB 3CU7A 5JPMB 4P3AA 5CQEA 4ITVA 1CFAA 4PUSA 3KLSA 1EA3A 4UU9C 1KJSA 4HW5A 3HQBA 3MD2A 3VDXA 1AA7A 4D9JA 2B39A 3HQAA 4HWJA 5B4PB 4P39A 2A73B 4WB3A 4FXKB 2Z16A 4P3BA
chains in the Genus database with same CATH topology
4WB2A 5JPNB 4I6OA 1C5AA 3CU7A 4P3AA 1CFAA 3KLSA 4UU9C 1KJSA 4HW5A 3HQBA 2B39A 3HQAA 5B4PB 4HWJA 4P39A 2A73B 4WB3A 4FXKB 4P3BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WB2 A;  5JPN B;  4I6O A;  1C5A A;  3CU7 A;  4P3A A;  1CFA A;  3KLS A;  4UU9 C;  1KJS A;  4HW5 A;  3HQB A;  2B39 A;  3HQA A;  5B4P B;  4HWJ A;  4P39 A;  2A73 B;  4WB3 A;  4FXK B;  4P3B A; 
#chains in the Genus database with same CATH topology
 4WB2 A;  4IQ4 A;  5JPN B;  4I6O A;  1C5A A;  4FXG B;  3CU7 A;  5JPM B;  4P3A A;  5CQE A;  4ITV A;  1CFA A;  4PUS A;  3KLS A;  1EA3 A;  4UU9 C;  1KJS A;  4HW5 A;  3HQB A;  3MD2 A;  3VDX A;  1AA7 A;  4D9J A;  2B39 A;  3HQA A;  4HWJ A;  5B4P B;  4P39 A;  2A73 B;  4WB3 A;  4FXK B;  2Z16 A;  4P3B A; 
#chains in the Genus database with same CATH homology
 4WB2 A;  5JPN B;  4I6O A;  1C5A A;  3CU7 A;  4P3A A;  1CFA A;  3KLS A;  4UU9 C;  1KJS A;  4HW5 A;  3HQB A;  2B39 A;  3HQA A;  5B4P B;  4HWJ A;  4P39 A;  2A73 B;  4WB3 A;  4FXK B;  4P3B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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