4POEA

Urate oxidase co-crystallized with uric acid and azide
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
295
structure length
295
Chain Sequence
SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxygen binding
molecule keywords Uricase
publication title Azide inhibition of urate oxidase.
pubmed doi rcsb
source organism Aspergillus flavus
total genus 82
structure length 295
sequence length 295
ec nomenclature ec 1.7.3.3: Factor independent urate hydroxylase.
pdb deposition date 2014-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01014 Uricase Uricase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.270.10 Alpha Beta Roll Urate Oxidase Urate Oxidase; 4poeA00
3PJKA 3PLHA 4D13A 4PUVA 1VAXA 2R5RA 1XY3A 3PK8A 1R56A 3F2MA 4D17A 2YZCA 3L9GA 4N9SA 3BJPA 3PKSA 4N3MA 3WLVA 3PLGA 1WRRA 3P9FA 3PKGA 4CW0A 5K95A 1XT4A 3PKLA 1R4UA 3PK3A 3CKUA 3PKTA 4CW6A 1R4SA 2YZBA 3LD4A 3P9OA 3PLEA 4N9VA 4POEA 4PR8A 5LL1A 1WS2A 5M98A 5FRCA 3PKKA 3PKFA 3PKUA 4N9MA 3LBGA 1R51A 4CW2A 2FXLA 4FSKA 4OP9A 5AYJA 3PLJA 1VAYA 2IC0A 4R99A 1XXJA 2ZKBA 3PK6A 1J2GA 4OP6A 2ZKAA 3PK5A 3OBPA 4MB8A 3L8WA 2IBAA 3GKOA 2YZDA 3PLMA 3PLIA 4D19A 3CKSA 2FUBA 4CW3A 3PK4A 5K9GA 4OQCA 1WS3A 3PKHA 4D12A 2ICQA 4R8XA 3BK8A 2PESA 2YZEA 3D2OA 4XFPA
chains in the Genus database with same CATH superfamily
3PJKA 3PLHA 4D13A 4PUVA 1VAXA 2R5RA 1XY3A 3PK8A 1R56A 3F2MA 4D17A 2YZCA 3L9GA 4N9SA 3BJPA 3PKSA 4N3MA 3WLVA 3PLGA 1WRRA 3P9FA 3PKGA 4CW0A 5K95A 1XT4A 3PKLA 1R4UA 3PK3A 3CKUA 3PKTA 4CW6A 1R4SA 2YZBA 3LD4A 3P9OA 3PLEA 4N9VA 4POEA 4PR8A 5LL1A 1WS2A 5M98A 5FRCA 3PKKA 3PKFA 3PKUA 4N9MA 3LBGA 1R51A 4CW2A 2FXLA 4FSKA 4OP9A 5AYJA 3PLJA 1VAYA 2IC0A 4R99A 1XXJA 2ZKBA 3PK6A 1J2GA 4OP6A 2ZKAA 3PK5A 3OBPA 4MB8A 3L8WA 2IBAA 3GKOA 2YZDA 3PLMA 3PLIA 4D19A 3CKSA 2FUBA 4CW3A 3PK4A 5K9GA 4OQCA 1WS3A 3PKHA 4D12A 2ICQA 4R8XA 3BK8A 2PESA 2YZEA 3D2OA 4XFPA
chains in the Genus database with same CATH topology
3PJKA 3PLHA 4D13A 4PUVA 1VAXA 2R5RA 1XY3A 3PK8A 1R56A 3F2MA 4D17A 2YZCA 3L9GA 4N9SA 3BJPA 3PKSA 4N3MA 3WLVA 3PLGA 1WRRA 3P9FA 3PKGA 4CW0A 5K95A 1XT4A 3PKLA 1R4UA 3PK3A 3CKUA 3PKTA 4CW6A 1R4SA 2YZBA 3LD4A 3P9OA 3PLEA 4N9VA 4POEA 4PR8A 5LL1A 1WS2A 5M98A 5FRCA 3PKKA 3PKFA 3PKUA 4N9MA 3LBGA 1R51A 4CW2A 2FXLA 4FSKA 4OP9A 5AYJA 3PLJA 1VAYA 2IC0A 4R99A 1XXJA 2ZKBA 3PK6A 1J2GA 4OP6A 2ZKAA 3PK5A 3OBPA 4MB8A 3L8WA 2IBAA 3GKOA 2YZDA 3PLMA 3PLIA 4D19A 3CKSA 2FUBA 4CW3A 3PK4A 5K9GA 4OQCA 1WS3A 3PKHA 4D12A 2ICQA 4R8XA 3BK8A 2PESA 2YZEA 3D2OA 4XFPA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3PJK A;  3PLH A;  4D13 A;  4PUV A;  1VAX A;  2R5R A;  1XY3 A;  3PK8 A;  1R56 A;  3F2M A;  4D17 A;  2YZC A;  3L9G A;  4N9S A;  3BJP A;  3PKS A;  4N3M A;  3WLV A;  3PLG A;  1WRR A;  3P9F A;  3PKG A;  4CW0 A;  5K95 A;  1XT4 A;  3PKL A;  1R4U A;  3PK3 A;  3CKU A;  3PKT A;  4CW6 A;  1R4S A;  2YZB A;  3LD4 A;  3P9O A;  3PLE A;  4N9V A;  4POE A;  4PR8 A;  5LL1 A;  1WS2 A;  5M98 A;  5FRC A;  3PKK A;  3PKF A;  3PKU A;  4N9M A;  3LBG A;  1R51 A;  4CW2 A;  2FXL A;  4FSK A;  4OP9 A;  5AYJ A;  3PLJ A;  1VAY A;  2IC0 A;  4R99 A;  1XXJ A;  2ZKB A;  3PK6 A;  1J2G A;  4OP6 A;  2ZKA A;  3PK5 A;  3OBP A;  4MB8 A;  3L8W A;  2IBA A;  3GKO A;  2YZD A;  3PLM A;  3PLI A;  4D19 A;  3CKS A;  2FUB A;  4CW3 A;  3PK4 A;  5K9G A;  4OQC A;  1WS3 A;  3PKH A;  4D12 A;  2ICQ A;  4R8X A;  3BK8 A;  2PES A;  2YZE A;  3D2O A;  4XFP A; 
#chains in the Genus database with same CATH topology
 3PJK A;  3PLH A;  4D13 A;  4PUV A;  1VAX A;  2R5R A;  1XY3 A;  3PK8 A;  1R56 A;  3F2M A;  4D17 A;  2YZC A;  3L9G A;  4N9S A;  3BJP A;  3PKS A;  4N3M A;  3WLV A;  3PLG A;  1WRR A;  3P9F A;  3PKG A;  4CW0 A;  5K95 A;  1XT4 A;  3PKL A;  1R4U A;  3PK3 A;  3CKU A;  3PKT A;  4CW6 A;  1R4S A;  2YZB A;  3LD4 A;  3P9O A;  3PLE A;  4N9V A;  4POE A;  4PR8 A;  5LL1 A;  1WS2 A;  5M98 A;  5FRC A;  3PKK A;  3PKF A;  3PKU A;  4N9M A;  3LBG A;  1R51 A;  4CW2 A;  2FXL A;  4FSK A;  4OP9 A;  5AYJ A;  3PLJ A;  1VAY A;  2IC0 A;  4R99 A;  1XXJ A;  2ZKB A;  3PK6 A;  1J2G A;  4OP6 A;  2ZKA A;  3PK5 A;  3OBP A;  4MB8 A;  3L8W A;  2IBA A;  3GKO A;  2YZD A;  3PLM A;  3PLI A;  4D19 A;  3CKS A;  2FUB A;  4CW3 A;  3PK4 A;  5K9G A;  4OQC A;  1WS3 A;  3PKH A;  4D12 A;  2ICQ A;  4R8X A;  3BK8 A;  2PES A;  2YZE A;  3D2O A;  4XFP A; 
#chains in the Genus database with same CATH homology
 3PJK A;  3PLH A;  4D13 A;  4PUV A;  1VAX A;  2R5R A;  1XY3 A;  3PK8 A;  1R56 A;  3F2M A;  4D17 A;  2YZC A;  3L9G A;  4N9S A;  3BJP A;  3PKS A;  4N3M A;  3WLV A;  3PLG A;  1WRR A;  3P9F A;  3PKG A;  4CW0 A;  5K95 A;  1XT4 A;  3PKL A;  1R4U A;  3PK3 A;  3CKU A;  3PKT A;  4CW6 A;  1R4S A;  2YZB A;  3LD4 A;  3P9O A;  3PLE A;  4N9V A;  4POE A;  4PR8 A;  5LL1 A;  1WS2 A;  5M98 A;  5FRC A;  3PKK A;  3PKF A;  3PKU A;  4N9M A;  3LBG A;  1R51 A;  4CW2 A;  2FXL A;  4FSK A;  4OP9 A;  5AYJ A;  3PLJ A;  1VAY A;  2IC0 A;  4R99 A;  1XXJ A;  2ZKB A;  3PK6 A;  1J2G A;  4OP6 A;  2ZKA A;  3PK5 A;  3OBP A;  4MB8 A;  3L8W A;  2IBA A;  3GKO A;  2YZD A;  3PLM A;  3PLI A;  4D19 A;  3CKS A;  2FUB A;  4CW3 A;  3PK4 A;  5K9G A;  4OQC A;  1WS3 A;  3PKH A;  4D12 A;  2ICQ A;  4R8X A;  3BK8 A;  2PES A;  2YZE A;  3D2O A;  4XFP A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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