5CSCA

Structure of an open form of chicken heart citrate synthase at 2.8 angstroms resolution
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxo-acid-lyase
source organism Gallus gallus
publication title Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution
pubmed doi rcsb
molecule keywords CITRATE SYNTHASE
total genus 125
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 5cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 5cscA01
4JADA 1CTSA 5CTSA 3ENJA 1IXEA 2C6XA 6CSCA 1CSCA 1CSHA 1NXEA 1CSIA 1AL6A 3O8JA 1CSSA 5CSCB 1OWBA 2R26A 4JAFA 1VGPA 2IFCA 4G6BA 4XGHA 3TQGA 1AJ8A 4CSCA 4YBOA 2P2WA 4E6YA 4TVMA 6CTSA 3MSUA 2CSCA 1O7XA 2IBPA 3HWKA 1CSRA 4JAGA 1OWCA 1NXGA 1IOMA 2H12A 1AMZA 4CTSA 1A59A 4JAEA 2R9EA 3CSCA 5CSCA 1VGMA 2CTSA
chains in the Genus database with same CATH superfamily
4JADA 1CTSA 5CTSA 3ENJA 1IXEA 2C6XA 6CSCA 1CSCA 1CSHA 1NXEA 1CSIA 1AL6A 3O8JA 1CSSA 5CSCB 1OWBA 2R26A 4JAFA 1VGPA 2IFCA 4G6BA 4XGHA 3TQGA 1AJ8A 4CSCA 4TVMA 2P2WA 4YBOA 4E6YA 6CTSA 3MSUA 2CSCA 1O7XA 2IBPA 3HWKA 1CSRA 4JAGA 1OWCA 1NXGA 1IOMA 2H12A 1AMZA 4CTSA 1A59A 4JAEA 2R9EA 3CSCA 5CSCA 1VGMA 2CTSA
chains in the Genus database with same CATH topology
4JADA 1CTSA 5CTSA 3ENJA 1IXEA 2C6XA 6CSCA 1CSCA 1CSHA 1NXEA 1CSIA 1AL6A 3O8JA 1CSSA 5CSCB 1OWBA 2R26A 4JAFA 1VGPA 2IFCA 4G6BA 4XGHA 3TQGA 1AJ8A 4CSCA 4YBOA 2P2WA 4E6YA 4TVMA 6CTSA 3MSUA 2CSCA 1O7XA 2IBPA 3HWKA 1CSRA 4JAGA 1OWCA 1NXGA 1IOMA 2H12A 1AMZA 4CTSA 1A59A 4JAEA 2R9EA 3CSCA 5CSCA 1VGMA 2CTSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAD A;  1CTS A;  5CTS A;  3ENJ A;  1IXE A;  2C6X A;  6CSC A;  1CSC A;  1CSH A;  1NXE A;  1CSI A;  1AL6 A;  3O8J A;  1CSS A;  5CSC B;  1OWB A;  2R26 A;  4JAF A;  1VGP A;  2IFC A;  4G6B A;  4XGH A;  3TQG A;  1AJ8 A;  4CSC A;  4YBO A;  2P2W A;  4E6Y A;  4TVM A;  6CTS A;  3MSU A;  2CSC A;  1O7X A;  2IBP A;  3HWK A;  1CSR A;  4JAG A;  1OWC A;  1NXG A;  1IOM A;  2H12 A;  1AMZ A;  4CTS A;  1A59 A;  4JAE A;  2R9E A;  3CSC A;  5CSC A;  1VGM A;  2CTS A; 
#chains in the Genus database with same CATH topology
 4JAD A;  1CTS A;  5CTS A;  3ENJ A;  1IXE A;  2C6X A;  6CSC A;  1CSC A;  1CSH A;  1NXE A;  1CSI A;  1AL6 A;  3O8J A;  1CSS A;  5CSC B;  1OWB A;  2R26 A;  4JAF A;  1VGP A;  2IFC A;  4G6B A;  4XGH A;  3TQG A;  1AJ8 A;  4CSC A;  4TVM A;  2P2W A;  4YBO A;  4E6Y A;  6CTS A;  3MSU A;  2CSC A;  1O7X A;  2IBP A;  3HWK A;  1CSR A;  4JAG A;  1OWC A;  1NXG A;  1IOM A;  2H12 A;  1AMZ A;  4CTS A;  1A59 A;  4JAE A;  2R9E A;  3CSC A;  5CSC A;  1VGM A;  2CTS A; 
#chains in the Genus database with same CATH homology
 4JAD A;  1CTS A;  5CTS A;  3ENJ A;  1IXE A;  2C6X A;  6CSC A;  1CSC A;  1CSH A;  1NXE A;  1CSI A;  1AL6 A;  3O8J A;  1CSS A;  5CSC B;  1OWB A;  2R26 A;  4JAF A;  1VGP A;  2IFC A;  4G6B A;  4XGH A;  3TQG A;  1AJ8 A;  4CSC A;  4YBO A;  2P2W A;  4E6Y A;  4TVM A;  6CTS A;  3MSU A;  2CSC A;  1O7X A;  2IBP A;  3HWK A;  1CSR A;  4JAG A;  1OWC A;  1NXG A;  1IOM A;  2H12 A;  1AMZ A;  4CTS A;  1A59 A;  4JAE A;  2R9E A;  3CSC A;  5CSC A;  1VGM A;  2CTS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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