5CSCA

Structure of an open form of chicken heart citrate synthase at 2.8 angstroms resolution
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution
pubmed doi rcsb
molecule tags Oxo-acid-lyase
source organism Gallus gallus
molecule keywords CITRATE SYNTHASE
total genus 125
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 5cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 5cscA01
4G6BA 1OWBA 1A59A 1O7XA 1VGPA 1IOMA 3MSUA 6CTSA 4TVMA 4JAGA 1CSIA 4E6YA 4CSCA 1NXEA 6CSCA 2IBPA 1IXEA 1CTSA 2P2WA 4CTSA 5CSCA 4XGHA 5CSCB 2R9EA 1CSHA 1OWCA 2CTSA 3HWKA 1NXGA 2H12A 5CTSA 3ENJA 2CSCA 2R26A 1CSSA 3TQGA 1AL6A 1CSCA 4JAEA 2C6XA 4YBOA 1CSRA 4JADA 3O8JA 1AMZA 1VGMA 3CSCA 2IFCA 4JAFA 1AJ8A
chains in the Genus database with same CATH superfamily
4G6BA 1OWBA 1A59A 1O7XA 1VGPA 1IOMA 3MSUA 6CTSA 4TVMA 4JAGA 1CSIA 4E6YA 4CSCA 1NXEA 6CSCA 2IBPA 1IXEA 1CTSA 2P2WA 4CTSA 5CSCA 4XGHA 5CSCB 2R9EA 1CSHA 1OWCA 2CTSA 3HWKA 1NXGA 2H12A 5CTSA 3ENJA 2CSCA 2R26A 1CSSA 3TQGA 1AL6A 1CSCA 4JAEA 2C6XA 4YBOA 1CSRA 4JADA 3O8JA 1AMZA 1VGMA 3CSCA 2IFCA 4JAFA 1AJ8A
chains in the Genus database with same CATH topology
4G6BA 1OWBA 1A59A 1O7XA 1VGPA 1IOMA 3MSUA 6CTSA 4TVMA 4JAGA 1CSIA 4E6YA 4CSCA 1NXEA 6CSCA 2IBPA 1IXEA 1CTSA 2P2WA 4CTSA 5CSCA 4XGHA 5CSCB 2R9EA 1CSHA 1OWCA 2CTSA 3HWKA 1NXGA 2H12A 5CTSA 3ENJA 2CSCA 2R26A 1CSSA 3TQGA 1AL6A 1CSCA 4JAEA 2C6XA 4YBOA 1CSRA 4JADA 3O8JA 1AMZA 1VGMA 3CSCA 2IFCA 4JAFA 1AJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G6B A;  1OWB A;  1A59 A;  1O7X A;  1VGP A;  1IOM A;  3MSU A;  6CTS A;  4TVM A;  4JAG A;  1CSI A;  4E6Y A;  4CSC A;  1NXE A;  6CSC A;  2IBP A;  1IXE A;  1CTS A;  2P2W A;  4CTS A;  5CSC A;  4XGH A;  5CSC B;  2R9E A;  1CSH A;  1OWC A;  2CTS A;  3HWK A;  1NXG A;  2H12 A;  5CTS A;  3ENJ A;  2CSC A;  2R26 A;  1CSS A;  3TQG A;  1AL6 A;  1CSC A;  4JAE A;  2C6X A;  4YBO A;  1CSR A;  4JAD A;  3O8J A;  1AMZ A;  1VGM A;  3CSC A;  2IFC A;  4JAF A;  1AJ8 A; 
#chains in the Genus database with same CATH topology
 4G6B A;  1OWB A;  1A59 A;  1O7X A;  1VGP A;  1IOM A;  3MSU A;  6CTS A;  4TVM A;  4JAG A;  1CSI A;  4E6Y A;  4CSC A;  1NXE A;  6CSC A;  2IBP A;  1IXE A;  1CTS A;  2P2W A;  4CTS A;  5CSC A;  4XGH A;  5CSC B;  2R9E A;  1CSH A;  1OWC A;  2CTS A;  3HWK A;  1NXG A;  2H12 A;  5CTS A;  3ENJ A;  2CSC A;  2R26 A;  1CSS A;  3TQG A;  1AL6 A;  1CSC A;  4JAE A;  2C6X A;  4YBO A;  1CSR A;  4JAD A;  3O8J A;  1AMZ A;  1VGM A;  3CSC A;  2IFC A;  4JAF A;  1AJ8 A; 
#chains in the Genus database with same CATH homology
 4G6B A;  1OWB A;  1A59 A;  1O7X A;  1VGP A;  1IOM A;  3MSU A;  6CTS A;  4TVM A;  4JAG A;  1CSI A;  4E6Y A;  4CSC A;  1NXE A;  6CSC A;  2IBP A;  1IXE A;  1CTS A;  2P2W A;  4CTS A;  5CSC A;  4XGH A;  5CSC B;  2R9E A;  1CSH A;  1OWC A;  2CTS A;  3HWK A;  1NXG A;  2H12 A;  5CTS A;  3ENJ A;  2CSC A;  2R26 A;  1CSS A;  3TQG A;  1AL6 A;  1CSC A;  4JAE A;  2C6X A;  4YBO A;  1CSR A;  4JAD A;  3O8J A;  1AMZ A;  1VGM A;  3CSC A;  2IFC A;  4JAF A;  1AJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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