5CW7B

Crystal structure of the paaa2-pare2 antitoxin-toxin complex
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
95
structure length
95
Chain Sequence
MLPVLWLESADTDLDDITSYIARFDIDAAERLWQRLRGCVLPLSEHPYLYPPSDRVPGLREIVAHPNYIILYRVTTSSVEVVNVIHARRQFPLEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.
pubmed doi rcsb
molecule tags Toxin
source organism Escherichia coli o157
molecule keywords PAAA2
total genus 26
structure length 95
sequence length 95
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2015-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 5cw7B00
4FXHA 3KXEA 4YY3Y 5IWHA 4LS4A 4NRNA 4FXED 4FXIA 4ML0B 4MMJA 3OEIC 4ML2A 2A6SA 4MMGA 4Q2UB 5IXLA 4MCXB 4LSYA 5CZEB 3BPQB 2KC9A 2KHEA 2KC8A 5CEGB 4MCTB 1WMIA 3G5OB 1Z8MA 2OTRA 4PX8A 5CZFC 5CW7B 2A6RA 2A6QE 4LTTA
chains in the Genus database with same CATH superfamily
4FXHA 3KXEA 4YY3Y 5IWHA 2FHZB 4LS4A 4NRNA 4FXED 4FXIA 4LTTA 4ML0B 4MMJA 3OEIC 4ML2A 2A6SA 4MMGA 4Q2UB 3VJ7A 3HI2B 5IXLA 2DFXE 4LSYA 4MCXB 5CZEB 3BPQB 2KC9A 5CEGB 2KC8A 4MCTB 2A8KA 1WMIA 2PD0A 3AO9A 3G5OB 1XQBA 1Z8MA 2DJHA 2OTRA 4PX8A 5CZFC 5CW7B 2A6RA 2A6QE 2KHEA 4FBDA
chains in the Genus database with same CATH topology
4FXHA 3KXEA 4YY3Y 5IWHA 4LS4A 4NRNA 4FXED 4FXIA 4ML0B 4MMJA 3OEIC 4ML2A 2A6SA 4MMGA 4Q2UB 5IXLA 4MCXB 4LSYA 5CZEB 3BPQB 2KC9A 2KHEA 2KC8A 5CEGB 4MCTB 1WMIA 3G5OB 1Z8MA 2OTRA 4PX8A 5CZFC 5CW7B 2A6RA 2A6QE 4LTTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FXH A;  3KXE A;  4YY3 Y;  5IWH A;  4LS4 A;  4NRN A;  4FXE D;  4FXI A;  4ML0 B;  4MMJ A;  3OEI C;  4ML2 A;  2A6S A;  4MMG A;  4Q2U B;  5IXL A;  4MCX B;  4LSY A;  5CZE B;  3BPQ B;  2KC9 A;  2KHE A;  2KC8 A;  5CEG B;  4MCT B;  1WMI A;  3G5O B;  1Z8M A;  2OTR A;  4PX8 A;  5CZF C;  5CW7 B;  2A6R A;  2A6Q E;  4LTT A; 
#chains in the Genus database with same CATH topology
 4FXH A;  3KXE A;  4YY3 Y;  5IWH A;  2FHZ B;  4LS4 A;  4NRN A;  4FXE D;  4FXI A;  4LTT A;  4ML0 B;  4MMJ A;  3OEI C;  4ML2 A;  2A6S A;  4MMG A;  4Q2U B;  3VJ7 A;  3HI2 B;  5IXL A;  2DFX E;  4LSY A;  4MCX B;  5CZE B;  3BPQ B;  2KC9 A;  5CEG B;  2KC8 A;  4MCT B;  2A8K A;  1WMI A;  2PD0 A;  3AO9 A;  3G5O B;  1XQB A;  1Z8M A;  2DJH A;  2OTR A;  4PX8 A;  5CZF C;  5CW7 B;  2A6R A;  2A6Q E;  2KHE A;  4FBD A; 
#chains in the Genus database with same CATH homology
 4FXH A;  3KXE A;  4YY3 Y;  5IWH A;  4LS4 A;  4NRN A;  4FXE D;  4FXI A;  4ML0 B;  4MMJ A;  3OEI C;  4ML2 A;  2A6S A;  4MMG A;  4Q2U B;  5IXL A;  4MCX B;  4LSY A;  5CZE B;  3BPQ B;  2KC9 A;  2KHE A;  2KC8 A;  5CEG B;  4MCT B;  1WMI A;  3G5O B;  1Z8M A;  2OTR A;  4PX8 A;  5CZF C;  5CW7 B;  2A6R A;  2A6Q E;  4LTT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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