5CW7B

Crystal structure of the paaa2-pare2 antitoxin-toxin complex
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
95
structure length
95
Chain Sequence
MLPVLWLESADTDLDDITSYIARFDIDAAERLWQRLRGCVLPLSEHPYLYPPSDRVPGLREIVAHPNYIILYRVTTSSVEVVNVIHARRQFPLEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.
pubmed doi rcsb
molecule keywords PAAA2
molecule tags Toxin
source organism Escherichia coli o157
total genus 26
structure length 95
sequence length 95
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2015-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 5cw7B00
5CZEB 4NRNA 4LSYA 5IWHA 2A6QE 5CEGB 3BPQB 4MMGA 4ML0B 4Q2UB 3G5OB 4LTTA 4FXHA 4ML2A 4MCTB 5IXLA 1Z8MA 2KHEA 5CZFC 4MCXB 4FXIA 2A6SA 1WMIA 4PX8A 2A6RA 3OEIC 5CW7B 4MMJA 2OTRA 2KC8A 2KC9A 4FXED 3KXEA 4YY3Y 4LS4A
chains in the Genus database with same CATH superfamily
5CZEB 4NRNA 2A8KA 4LSYA 2DFXE 5IWHA 2A6QE 5CEGB 3AO9A 3BPQB 4MMGA 4ML0B 4Q2UB 3HI2B 3G5OB 2PD0A 2DJHA 4LTTA 4FXHA 4ML2A 4MCTB 3VJ7A 5IXLA 1Z8MA 2KHEA 5CZFC 4MCXB 4FXIA 2A6SA 1WMIA 4PX8A 2FHZB 2A6RA 3OEIC 5CW7B 4MMJA 2OTRA 2KC8A 2KC9A 4FXED 1XQBA 3KXEA 4YY3Y 4FBDA 4LS4A
chains in the Genus database with same CATH topology
5CZEB 4NRNA 4LSYA 5IWHA 2A6QE 5CEGB 3BPQB 4MMGA 4ML0B 4Q2UB 3G5OB 4LTTA 4FXHA 4ML2A 4MCTB 5IXLA 1Z8MA 2KHEA 5CZFC 4MCXB 4FXIA 2A6SA 1WMIA 4PX8A 2A6RA 3OEIC 5CW7B 4MMJA 2OTRA 2KC8A 2KC9A 4FXED 3KXEA 4YY3Y 4LS4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CZE B;  4NRN A;  4LSY A;  5IWH A;  2A6Q E;  5CEG B;  3BPQ B;  4MMG A;  4ML0 B;  4Q2U B;  3G5O B;  4LTT A;  4FXH A;  4ML2 A;  4MCT B;  5IXL A;  1Z8M A;  2KHE A;  5CZF C;  4MCX B;  4FXI A;  2A6S A;  1WMI A;  4PX8 A;  2A6R A;  3OEI C;  5CW7 B;  4MMJ A;  2OTR A;  2KC8 A;  2KC9 A;  4FXE D;  3KXE A;  4YY3 Y;  4LS4 A; 
#chains in the Genus database with same CATH topology
 5CZE B;  4NRN A;  2A8K A;  4LSY A;  2DFX E;  5IWH A;  2A6Q E;  5CEG B;  3AO9 A;  3BPQ B;  4MMG A;  4ML0 B;  4Q2U B;  3HI2 B;  3G5O B;  2PD0 A;  2DJH A;  4LTT A;  4FXH A;  4ML2 A;  4MCT B;  3VJ7 A;  5IXL A;  1Z8M A;  2KHE A;  5CZF C;  4MCX B;  4FXI A;  2A6S A;  1WMI A;  4PX8 A;  2FHZ B;  2A6R A;  3OEI C;  5CW7 B;  4MMJ A;  2OTR A;  2KC8 A;  2KC9 A;  4FXE D;  1XQB A;  3KXE A;  4YY3 Y;  4FBD A;  4LS4 A; 
#chains in the Genus database with same CATH homology
 5CZE B;  4NRN A;  4LSY A;  5IWH A;  2A6Q E;  5CEG B;  3BPQ B;  4MMG A;  4ML0 B;  4Q2U B;  3G5O B;  4LTT A;  4FXH A;  4ML2 A;  4MCT B;  5IXL A;  1Z8M A;  2KHE A;  5CZF C;  4MCX B;  4FXI A;  2A6S A;  1WMI A;  4PX8 A;  2A6R A;  3OEI C;  5CW7 B;  4MMJ A;  2OTR A;  2KC8 A;  2KC9 A;  4FXE D;  3KXE A;  4YY3 Y;  4LS4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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