5FVEA

Crystal structure of helicobacter pylori beta clamp in complex with 3, 4-difluorobenzamide
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
374
structure length
367
Chain Sequence
MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQSSDKEGVGTINGKKFLDIISCLKDSNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFPVIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKRELAGILMQFDQKHQTLSVVGTDTKRLSYTQLEKISIHSTEEDISCILPKRALLEILKLFYENFSFKSDGMLAVIENEMHTFFTKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSSTIKLTLEKNNALFESLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLIQESLNAKISTLMMPITL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
pubmed doi rcsb
molecule tags Transferase
source organism Helicobacter pylori
molecule keywords DNA POLYMERASE III SUBUNIT BETA
total genus 87
structure length 367
sequence length 374
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2016-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 5fveA02
3F1VA 4K3OA 3D1EA 1MMIA 4N94A 5FVEA 4PNWA 2AVTA 4K3LA 3D1FA 3Q4LA 4K74A 4N98A 4MJQA 3L10A 3Q4KA 4TR6A 3QSBA 4N99A 4TSZA 5AH2A 2POLA 4TRTA 4TR8A 3BEPA 4K3PA 4K3QA 5AGVA 2XURA 3T0PA 5FRQA 4K3SA 4N97A 5AH4A 3PWEA 4K3KA 4K3MA 4MJRA 4PNUA 4TR7A 5AGUA 1JQJA 1UNNA 3L0XA 4K3RA 1VPKA 3QSBB 4N9AA 4OVHA 1OK7A 4RKIA 3RB9A 3P16A 3L0WA 4OVGA 3Q4JA 4S3IA 4N96A 2AWAA 3PGEB 1JQLA 3D1GA 4MJPA 4N95A 4OVFA 4PNVA
chains in the Genus database with same CATH superfamily
3F1VA 4K3OA 3D1EA 1MMIA 4N94A 5FVEA 4PNWA 3L0XB 2AVTA 4K3LA 3D1FA 3Q4LA 3L0WB 4K74A 4N98A 4MJQA 3L10A 3Q4KA 4TR6A 3QSBA 4N99A 4TSZA 5AH2A 3PGEA 2POLA 4TRTA 4TR8A 3BEPA 4K3PA 4K3QA 5AGVA 2XURA 3T0PA 5FRQA 4K3SA 4N97A 5AH4A 3PWEA 4K3KA 4K3MA 4MJRA 4PNUA 4TR7A 5AGUA 1JQJA 1UNNA 3L0XA 4K3RA 1VPKA 3QSBB 4N9AA 4OVHA 1OK7A 3L10B 4RKIA 3RB9A 3P16A 3L0WA 4OVGA 3Q4JA 4S3IA 4N96A 2AWAA 3PGEB 1JQLA 3D1GA 4MJPA 4N95A 4OVFA 4PNVA
chains in the Genus database with same CATH topology
3F1VA 4K3OA 3D1EA 1MMIA 4N94A 5FVEA 4PNWA 2AVTA 4K3LA 3D1FA 3Q4LA 4K74A 4N98A 4MJQA 3L10A 3Q4KA 4TR6A 3QSBA 4N99A 4TSZA 5AH2A 2POLA 4TRTA 4TR8A 3BEPA 4K3PA 4K3QA 5AGVA 2XURA 3T0PA 5FRQA 4K3SA 4N97A 5AH4A 3PWEA 4K3KA 4K3MA 4MJRA 4PNUA 4TR7A 5AGUA 1JQJA 1UNNA 3L0XA 4K3RA 1VPKA 3QSBB 4N9AA 4OVHA 1OK7A 4RKIA 3RB9A 3P16A 3L0WA 4OVGA 3Q4JA 4S3IA 4N96A 2AWAA 3PGEB 1JQLA 3D1GA 4MJPA 4N95A 4OVFA 4PNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F1V A;  4K3O A;  3D1E A;  1MMI A;  4N94 A;  5FVE A;  4PNW A;  2AVT A;  4K3L A;  3D1F A;  3Q4L A;  4K74 A;  4N98 A;  4MJQ A;  3L10 A;  3Q4K A;  4TR6 A;  3QSB A;  4N99 A;  4TSZ A;  5AH2 A;  2POL A;  4TRT A;  4TR8 A;  3BEP A;  4K3P A;  4K3Q A;  5AGV A;  2XUR A;  3T0P A;  5FRQ A;  4K3S A;  4N97 A;  5AH4 A;  3PWE A;  4K3K A;  4K3M A;  4MJR A;  4PNU A;  4TR7 A;  5AGU A;  1JQJ A;  1UNN A;  3L0X A;  4K3R A;  1VPK A;  3QSB B;  4N9A A;  4OVH A;  1OK7 A;  4RKI A;  3RB9 A;  3P16 A;  3L0W A;  4OVG A;  3Q4J A;  4S3I A;  4N96 A;  2AWA A;  3PGE B;  1JQL A;  3D1G A;  4MJP A;  4N95 A;  4OVF A;  4PNV A; 
#chains in the Genus database with same CATH topology
 3F1V A;  4K3O A;  3D1E A;  1MMI A;  4N94 A;  5FVE A;  4PNW A;  3L0X B;  2AVT A;  4K3L A;  3D1F A;  3Q4L A;  3L0W B;  4K74 A;  4N98 A;  4MJQ A;  3L10 A;  3Q4K A;  4TR6 A;  3QSB A;  4N99 A;  4TSZ A;  5AH2 A;  3PGE A;  2POL A;  4TRT A;  4TR8 A;  3BEP A;  4K3P A;  4K3Q A;  5AGV A;  2XUR A;  3T0P A;  5FRQ A;  4K3S A;  4N97 A;  5AH4 A;  3PWE A;  4K3K A;  4K3M A;  4MJR A;  4PNU A;  4TR7 A;  5AGU A;  1JQJ A;  1UNN A;  3L0X A;  4K3R A;  1VPK A;  3QSB B;  4N9A A;  4OVH A;  1OK7 A;  3L10 B;  4RKI A;  3RB9 A;  3P16 A;  3L0W A;  4OVG A;  3Q4J A;  4S3I A;  4N96 A;  2AWA A;  3PGE B;  1JQL A;  3D1G A;  4MJP A;  4N95 A;  4OVF A;  4PNV A; 
#chains in the Genus database with same CATH homology
 3F1V A;  4K3O A;  3D1E A;  1MMI A;  4N94 A;  5FVE A;  4PNW A;  2AVT A;  4K3L A;  3D1F A;  3Q4L A;  4K74 A;  4N98 A;  4MJQ A;  3L10 A;  3Q4K A;  4TR6 A;  3QSB A;  4N99 A;  4TSZ A;  5AH2 A;  2POL A;  4TRT A;  4TR8 A;  3BEP A;  4K3P A;  4K3Q A;  5AGV A;  2XUR A;  3T0P A;  5FRQ A;  4K3S A;  4N97 A;  5AH4 A;  3PWE A;  4K3K A;  4K3M A;  4MJR A;  4PNU A;  4TR7 A;  5AGU A;  1JQJ A;  1UNN A;  3L0X A;  4K3R A;  1VPK A;  3QSB B;  4N9A A;  4OVH A;  1OK7 A;  4RKI A;  3RB9 A;  3P16 A;  3L0W A;  4OVG A;  3Q4J A;  4S3I A;  4N96 A;  2AWA A;  3PGE B;  1JQL A;  3D1G A;  4MJP A;  4N95 A;  4OVF A;  4PNV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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