5I38A

Crystal structure of tyrosinase from bacillus megaterium with inhibitor kojic acid in the active site
Total Genus 103
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
286
structure length
286
Chain Sequence
YRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDIEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The unravelling of the complex pattern of tyrosinase inhibition.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Bacillus megaterium
molecule keywords Tyrosinase
total genus 103
structure length 286
sequence length 286
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 5i38A00
1HCYA 4OUAA 3WJMB 4P6SA 4Z0ZA 1BT2A 4L37B 4J6VA 1WX2A 1LNLA 3AWSA 3HHSB 3WKYA 3WJMA 3AX0A 3W6WA 2Y9XA 4P6RA 4HD6A 5CE9A 4L37A 5I3AA 2ZWGA 2AHLA 3HHSA 4J6UA 1LL1A 4J6TA 1NOLA 3AWVA 5I3BA 2ZWDA 3NM8A 4J3QA 4Z10A 3NQ5A 4D87A 2ZMYA 4Z0YA 1OXYA 4P6TA 3AWTA 4YZWA 3AWZA 4HD7A 1WX5A 2ZMXA 3NQ1A 2ZMZA 1JS8A 3QJOA 1BUGA 1LLAA 1HC1A 3W6QA 4HD4A 1WX4A 3AWWA 2Y9WA 5I38A 2ZWFA 2AHKA 1WXCA 4J3PA 4OUAB 3NPYA 3AWXA 3AWYA 3NQ0A 3GWJA 3AWUA 3NTMA 1BT1A 2P3XA 4J3RA 1BT3A 2ZWEA
chains in the Genus database with same CATH superfamily
1HCYA 4OUAA 3WJMB 4P6SA 4Z0ZA 1BT2A 4L37B 4J6VA 1WX2A 1LNLA 3AWSA 3HHSB 3WKYA 3WJMA 3AX0A 3W6WA 2Y9XA 4P6RA 4HD6A 5CE9A 4L37A 5I3AA 2ZWGA 2AHLA 3HHSA 4J6UA 1LL1A 4J6TA 1NOLA 3AWVA 5I3BA 2ZWDA 3NM8A 4J3QA 4Z10A 3NQ5A 4D87A 2ZMYA 4Z0YA 1OXYA 4P6TA 3AWTA 4YZWA 3AWZA 4HD7A 1WX5A 2ZMXA 3NQ1A 2ZMZA 1JS8A 3QJOA 1BUGA 1LLAA 1HC1A 3W6QA 4HD4A 1WX4A 3AWWA 2Y9WA 5I38A 2ZWFA 2AHKA 1WXCA 4J3PA 4OUAB 3NPYA 3AWXA 3AWYA 3NQ0A 3GWJA 3AWUA 3NTMA 1BT1A 2P3XA 4J3RA 1BT3A 2ZWEA
chains in the Genus database with same CATH topology
1HCYA 4OUAA 3WJMB 4P6SA 4Z0ZA 1BT2A 4L37B 4J6VA 1WX2A 1LNLA 3AWSA 3HHSB 3WKYA 3WJMA 3AX0A 3W6WA 2Y9XA 4P6RA 4HD6A 5CE9A 4L37A 5I3AA 2ZWGA 2AHLA 3HHSA 4J6UA 1LL1A 4J6TA 1NOLA 3AWVA 5I3BA 2ZWDA 3NM8A 4J3QA 4Z10A 3NQ5A 4D87A 2ZMYA 4Z0YA 1OXYA 4P6TA 3AWTA 4YZWA 3AWZA 4HD7A 1WX5A 2ZMXA 3NQ1A 2ZMZA 1JS8A 3QJOA 1BUGA 1LLAA 1HC1A 3W6QA 4HD4A 1WX4A 3AWWA 2Y9WA 5I38A 2ZWFA 2AHKA 1WXCA 4J3PA 4OUAB 3NPYA 3AWXA 3AWYA 3NQ0A 3GWJA 3AWUA 3NTMA 1BT1A 2P3XA 4J3RA 1BT3A 2ZWEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HCY A;  4OUA A;  3WJM B;  4P6S A;  4Z0Z A;  1BT2 A;  4L37 B;  4J6V A;  1WX2 A;  1LNL A;  3AWS A;  3HHS B;  3WKY A;  3WJM A;  3AX0 A;  3W6W A;  2Y9X A;  4P6R A;  4HD6 A;  5CE9 A;  4L37 A;  5I3A A;  2ZWG A;  2AHL A;  3HHS A;  4J6U A;  1LL1 A;  4J6T A;  1NOL A;  3AWV A;  5I3B A;  2ZWD A;  3NM8 A;  4J3Q A;  4Z10 A;  3NQ5 A;  4D87 A;  2ZMY A;  4Z0Y A;  1OXY A;  4P6T A;  3AWT A;  4YZW A;  3AWZ A;  4HD7 A;  1WX5 A;  2ZMX A;  3NQ1 A;  2ZMZ A;  1JS8 A;  3QJO A;  1BUG A;  1LLA A;  1HC1 A;  3W6Q A;  4HD4 A;  1WX4 A;  3AWW A;  2Y9W A;  5I38 A;  2ZWF A;  2AHK A;  1WXC A;  4J3P A;  4OUA B;  3NPY A;  3AWX A;  3AWY A;  3NQ0 A;  3GWJ A;  3AWU A;  3NTM A;  1BT1 A;  2P3X A;  4J3R A;  1BT3 A;  2ZWE A; 
#chains in the Genus database with same CATH topology
 1HCY A;  4OUA A;  3WJM B;  4P6S A;  4Z0Z A;  1BT2 A;  4L37 B;  4J6V A;  1WX2 A;  1LNL A;  3AWS A;  3HHS B;  3WKY A;  3WJM A;  3AX0 A;  3W6W A;  2Y9X A;  4P6R A;  4HD6 A;  5CE9 A;  4L37 A;  5I3A A;  2ZWG A;  2AHL A;  3HHS A;  4J6U A;  1LL1 A;  4J6T A;  1NOL A;  3AWV A;  5I3B A;  2ZWD A;  3NM8 A;  4J3Q A;  4Z10 A;  3NQ5 A;  4D87 A;  2ZMY A;  4Z0Y A;  1OXY A;  4P6T A;  3AWT A;  4YZW A;  3AWZ A;  4HD7 A;  1WX5 A;  2ZMX A;  3NQ1 A;  2ZMZ A;  1JS8 A;  3QJO A;  1BUG A;  1LLA A;  1HC1 A;  3W6Q A;  4HD4 A;  1WX4 A;  3AWW A;  2Y9W A;  5I38 A;  2ZWF A;  2AHK A;  1WXC A;  4J3P A;  4OUA B;  3NPY A;  3AWX A;  3AWY A;  3NQ0 A;  3GWJ A;  3AWU A;  3NTM A;  1BT1 A;  2P3X A;  4J3R A;  1BT3 A;  2ZWE A; 
#chains in the Genus database with same CATH homology
 1HCY A;  4OUA A;  3WJM B;  4P6S A;  4Z0Z A;  1BT2 A;  4L37 B;  4J6V A;  1WX2 A;  1LNL A;  3AWS A;  3HHS B;  3WKY A;  3WJM A;  3AX0 A;  3W6W A;  2Y9X A;  4P6R A;  4HD6 A;  5CE9 A;  4L37 A;  5I3A A;  2ZWG A;  2AHL A;  3HHS A;  4J6U A;  1LL1 A;  4J6T A;  1NOL A;  3AWV A;  5I3B A;  2ZWD A;  3NM8 A;  4J3Q A;  4Z10 A;  3NQ5 A;  4D87 A;  2ZMY A;  4Z0Y A;  1OXY A;  4P6T A;  3AWT A;  4YZW A;  3AWZ A;  4HD7 A;  1WX5 A;  2ZMX A;  3NQ1 A;  2ZMZ A;  1JS8 A;  3QJO A;  1BUG A;  1LLA A;  1HC1 A;  3W6Q A;  4HD4 A;  1WX4 A;  3AWW A;  2Y9W A;  5I38 A;  2ZWF A;  2AHK A;  1WXC A;  4J3P A;  4OUA B;  3NPY A;  3AWX A;  3AWY A;  3NQ0 A;  3GWJ A;  3AWU A;  3NTM A;  1BT1 A;  2P3X A;  4J3R A;  1BT3 A;  2ZWE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...