6CSC | Genus

Total Genus 159

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	159
sequence length	437
structure length	437
Chain Sequence	ASSTNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPKAGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxo-acid-lyase
publication title	Trifluoroacetonyl Coenzyme A, an Inhibitor of Citrate Synthase, Binds in a Combination of Productive and Nonproductive Modes rcsb
molecule keywords	CITRATE SYNTHASE
total genus	159
structure length	437
sequence length	437
chains with identical sequence	B
ec nomenclature	ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date	1997-06-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00285	Citrate_synt	Citrate synthase, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp; domain 2	Cytochrome P450-Terp, domain 2	6cscA02
1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase; domain 1	Citrate Synthase, domain 1	6cscA01

2H12A 1CSRA 1AL6A 1A59A 3O8JA 3TQGA 4XGHA 4TVMA 1IXEA 2CTSA 5CTSA 2IFCA 1AMZA 1NXGA 2C6XA 1VGMA 4JAGA 1OWBA 1CSSA 4JADA 1NXEA 2P2WA 5CSCB 2R9EA 2R26A 3CSCA 4E6YA 3HWKA 2CSCA 1AJ8A 4CTSA 6CSCA 1CTSA 3ENJA 1CSCA 3MSUA 4JAEA 4YBOA 1IOMA 6CTSA 1CSHA 2IBPA 1CSIA 4CSCA 5CSCA 4JAFA 1VGPA 4G6BA 1O7XA 1OWCA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2H12 A;  1CSR A;  1AL6 A;  1A59 A;  3O8J A;  3TQG A;  4XGH A;  4TVM A;  1IXE A;  2CTS A;  5CTS A;  2IFC A;  1AMZ A;  1NXG A;  2C6X A;  1VGM A;  4JAG A;  1OWB A;  1CSS A;  4JAD A;  1NXE A;  2P2W A;  5CSC B;  2R9E A;  2R26 A;  3CSC A;  4E6Y A;  3HWK A;  2CSC A;  1AJ8 A;  4CTS A;  6CSC A;  1CTS A;  3ENJ A;  1CSC A;  3MSU A;  4JAE A;  4YBO A;  1IOM A;  6CTS A;  1CSH A;  2IBP A;  1CSI A;  4CSC A;  5CSC A;  4JAF A;  1VGP A;  4G6B A;  1O7X A;  1OWC A; 
#chains in the Genus database with same CATH topology
 2H12 A;  1CSR A;  1AL6 A;  1A59 A;  3O8J A;  3TQG A;  4XGH A;  4TVM A;  1IXE A;  2CTS A;  5CTS A;  2IFC A;  1AMZ A;  1NXG A;  2C6X A;  1VGM A;  4JAG A;  1OWB A;  1CSS A;  4JAD A;  1NXE A;  2P2W A;  5CSC B;  2R9E A;  2R26 A;  3CSC A;  4E6Y A;  3HWK A;  2CSC A;  1AJ8 A;  4CTS A;  6CSC A;  1CTS A;  3ENJ A;  1CSC A;  3MSU A;  4JAE A;  4YBO A;  1IOM A;  6CTS A;  1CSH A;  2IBP A;  1CSI A;  4CSC A;  5CSC A;  4JAF A;  1VGP A;  4G6B A;  1O7X A;  1OWC A; 
#chains in the Genus database with same CATH homology
 2H12 A;  1CSR A;  1AL6 A;  1A59 A;  3O8J A;  3TQG A;  4XGH A;  4TVM A;  1IXE A;  2CTS A;  5CTS A;  2IFC A;  1AMZ A;  1NXG A;  2C6X A;  1VGM A;  4JAG A;  1OWB A;  1CSS A;  4JAD A;  1NXE A;  2P2W A;  5CSC B;  2R9E A;  2R26 A;  3CSC A;  4E6Y A;  3HWK A;  2CSC A;  1AJ8 A;  4CTS A;  6CSC A;  1CTS A;  3ENJ A;  1CSC A;  3MSU A;  4JAE A;  4YBO A;  1IOM A;  6CTS A;  1CSH A;  2IBP A;  1CSI A;  4CSC A;  5CSC A;  4JAF A;  1VGP A;  4G6B A;  1O7X A;  1OWC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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6CSCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations