1DK8A

Crystal structure of the rgs-homologous domain of axin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
147
structure length
147
Chain Sequence
GSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords AXIN
publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
source organism Homo sapiens
total genus 50
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 1999-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1dk8A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1dk8A01
1AGRE 4TNBA 2OWIA 2CRPA 3KRXA 3C7KB 3KRWA 4MK0A 2V4ZB 2BT2A 1EZYA 4PNKA 2OJ4A 3PSCA 3NYNA 2BV1A 4TNDA 3CIKA 2DLVA 3UZTA 5HE3A 3NYOA 2IHBB 2JNUA 2EBZA 5HE0A 1OMWA 1FQJB 2D9JA 5HE1A 5DO9B 2JM5A 3PVWA 4EKDB 2AF0A 2IK8B 1CMZA 1EMUA 1FQKB 2IHDA 3V5WA 3PVUA 5HE2A 2BCJA 1FQIA 1EZTA 2GTPC 1DK8A 3C7LA 2ODEB
chains in the Genus database with same CATH superfamily
1AGRE 4TNBA 2OWIA 2CRPA 5REQB 3KRXA 3C7KB 3KRWA 4MK0A 2V4ZB 2BT2A 1EZYA 4PNKA 2OJ4A 3PSCA 3NYNA 2BV1A 4TNDA 3CIKA 2DLVA 3UZTA 3QYFA 5HE3A 3NYOA 2IHBB 2JNUA 2EBZA 5HE0A 4HTEA 3I5QA 1OMWA 1FQJB 2D9JA 5HE1A 5DO9B 2JM5A 3PVWA 4EKDB 2AF0A 2IK8B 1CMZA 1EMUA 1FQKB 2IHDA 3V5WA 3PVUA 5HE2A 2BCJA 1FQIA 1EZTA 2GTPC 1DK8A 3C7LA 2ODEB
chains in the Genus database with same CATH topology
1AGRE 4TNBA 2OWIA 2CRPA 5REQB 3KRXA 3C7KB 3KRWA 4MK0A 2V4ZB 2BT2A 1EZYA 4PNKA 2OJ4A 3PSCA 3NYNA 2BV1A 4TNDA 3CIKA 2DLVA 3UZTA 3QYFA 5HE3A 3NYOA 2IHBB 2JNUA 2EBZA 5HE0A 1OMWA 1FQJB 2D9JA 5HE1A 5DO9B 2JM5A 3PVWA 4EKDB 2AF0A 2IK8B 1CMZA 1EMUA 1FQKB 2IHDA 3V5WA 3PVUA 5HE2A 2BCJA 1FQIA 1EZTA 2GTPC 1DK8A 3C7LA 2ODEB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AGR E;  4TNB A;  2OWI A;  2CRP A;  3KRX A;  3C7K B;  3KRW A;  4MK0 A;  2V4Z B;  2BT2 A;  1EZY A;  4PNK A;  2OJ4 A;  3PSC A;  3NYN A;  2BV1 A;  4TND A;  3CIK A;  2DLV A;  3UZT A;  5HE3 A;  3NYO A;  2IHB B;  2JNU A;  2EBZ A;  5HE0 A;  1OMW A;  1FQJ B;  2D9J A;  5HE1 A;  5DO9 B;  2JM5 A;  3PVW A;  4EKD B;  2AF0 A;  2IK8 B;  1CMZ A;  1EMU A;  1FQK B;  2IHD A;  3V5W A;  3PVU A;  5HE2 A;  2BCJ A;  1FQI A;  1EZT A;  2GTP C;  1DK8 A;  3C7L A;  2ODE B; 
#chains in the Genus database with same CATH topology
 1AGR E;  4TNB A;  2OWI A;  2CRP A;  5REQ B;  3KRX A;  3C7K B;  3KRW A;  4MK0 A;  2V4Z B;  2BT2 A;  1EZY A;  4PNK A;  2OJ4 A;  3PSC A;  3NYN A;  2BV1 A;  4TND A;  3CIK A;  2DLV A;  3UZT A;  3QYF A;  5HE3 A;  3NYO A;  2IHB B;  2JNU A;  2EBZ A;  5HE0 A;  4HTE A;  3I5Q A;  1OMW A;  1FQJ B;  2D9J A;  5HE1 A;  5DO9 B;  2JM5 A;  3PVW A;  4EKD B;  2AF0 A;  2IK8 B;  1CMZ A;  1EMU A;  1FQK B;  2IHD A;  3V5W A;  3PVU A;  5HE2 A;  2BCJ A;  1FQI A;  1EZT A;  2GTP C;  1DK8 A;  3C7L A;  2ODE B; 
#chains in the Genus database with same CATH homology
 1AGR E;  4TNB A;  2OWI A;  2CRP A;  5REQ B;  3KRX A;  3C7K B;  3KRW A;  4MK0 A;  2V4Z B;  2BT2 A;  1EZY A;  4PNK A;  2OJ4 A;  3PSC A;  3NYN A;  2BV1 A;  4TND A;  3CIK A;  2DLV A;  3UZT A;  3QYF A;  5HE3 A;  3NYO A;  2IHB B;  2JNU A;  2EBZ A;  5HE0 A;  1OMW A;  1FQJ B;  2D9J A;  5HE1 A;  5DO9 B;  2JM5 A;  3PVW A;  4EKD B;  2AF0 A;  2IK8 B;  1CMZ A;  1EMU A;  1FQK B;  2IHD A;  3V5W A;  3PVU A;  5HE2 A;  2BCJ A;  1FQI A;  1EZT A;  2GTP C;  1DK8 A;  3C7L A;  2ODE B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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