2BT2A

Structure of the regulator of g-protein signaling 16
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
143
structure length
143
Chain Sequence
NLYFQSMRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords REGULATOR OF G-PROTEIN SIGNALING 16
publication title Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 57
structure length 143
sequence length 143
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2005-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2bt2A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2bt2A01
5HE0A 1DK8A 2BCJA 3NYNA 2IHDA 1FQJB 3PSCA 5DO9B 2D9JA 2CRPA 1AGRE 2JM5A 3UZTA 2EBZA 2OWIA 5HE1A 3KRXA 3PVWA 3NYOA 1EZTA 2DLVA 5HE2A 1FQKB 4TNBA 1EZYA 5HE3A 2IHBB 1CMZA 3KRWA 3C7KB 2JNUA 2V4ZB 3PVUA 4EKDB 2AF0A 1OMWA 2IK8B 4PNKA 4MK0A 2ODEB 2OJ4A 2BT2A 2GTPC 3V5WA 2BV1A 3C7LA 4TNDA 1EMUA 1FQIA 3CIKA
chains in the Genus database with same CATH superfamily
5HE0A 5REQB 1DK8A 2BCJA 3NYNA 2IHDA 1FQJB 3PSCA 5DO9B 2D9JA 2CRPA 1AGRE 2JM5A 3UZTA 4HTEA 2EBZA 2OWIA 5HE1A 3KRXA 3PVWA 3I5QA 3NYOA 1EZTA 2DLVA 5HE2A 1FQKB 4TNBA 1EZYA 5HE3A 2IHBB 1CMZA 3KRWA 3C7KB 2JNUA 2V4ZB 3PVUA 4EKDB 2AF0A 1OMWA 2IK8B 4PNKA 4MK0A 2ODEB 2OJ4A 3QYFA 2BT2A 2GTPC 3V5WA 2BV1A 3C7LA 4TNDA 1EMUA 1FQIA 3CIKA
chains in the Genus database with same CATH topology
5HE0A 5REQB 1DK8A 2BCJA 3NYNA 2IHDA 1FQJB 3PSCA 5DO9B 2D9JA 2CRPA 1AGRE 2JM5A 3UZTA 2EBZA 2OWIA 5HE1A 3KRXA 3PVWA 3NYOA 1EZTA 2DLVA 5HE2A 1FQKB 4TNBA 1EZYA 5HE3A 2IHBB 1CMZA 3KRWA 3C7KB 2JNUA 2V4ZB 3PVUA 4EKDB 2AF0A 1OMWA 2IK8B 4PNKA 4MK0A 2ODEB 2OJ4A 3QYFA 2BT2A 2GTPC 3V5WA 2BV1A 3C7LA 4TNDA 1EMUA 1FQIA 3CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE0 A;  1DK8 A;  2BCJ A;  3NYN A;  2IHD A;  1FQJ B;  3PSC A;  5DO9 B;  2D9J A;  2CRP A;  1AGR E;  2JM5 A;  3UZT A;  2EBZ A;  2OWI A;  5HE1 A;  3KRX A;  3PVW A;  3NYO A;  1EZT A;  2DLV A;  5HE2 A;  1FQK B;  4TNB A;  1EZY A;  5HE3 A;  2IHB B;  1CMZ A;  3KRW A;  3C7K B;  2JNU A;  2V4Z B;  3PVU A;  4EKD B;  2AF0 A;  1OMW A;  2IK8 B;  4PNK A;  4MK0 A;  2ODE B;  2OJ4 A;  2BT2 A;  2GTP C;  3V5W A;  2BV1 A;  3C7L A;  4TND A;  1EMU A;  1FQI A;  3CIK A; 
#chains in the Genus database with same CATH topology
 5HE0 A;  5REQ B;  1DK8 A;  2BCJ A;  3NYN A;  2IHD A;  1FQJ B;  3PSC A;  5DO9 B;  2D9J A;  2CRP A;  1AGR E;  2JM5 A;  3UZT A;  4HTE A;  2EBZ A;  2OWI A;  5HE1 A;  3KRX A;  3PVW A;  3I5Q A;  3NYO A;  1EZT A;  2DLV A;  5HE2 A;  1FQK B;  4TNB A;  1EZY A;  5HE3 A;  2IHB B;  1CMZ A;  3KRW A;  3C7K B;  2JNU A;  2V4Z B;  3PVU A;  4EKD B;  2AF0 A;  1OMW A;  2IK8 B;  4PNK A;  4MK0 A;  2ODE B;  2OJ4 A;  3QYF A;  2BT2 A;  2GTP C;  3V5W A;  2BV1 A;  3C7L A;  4TND A;  1EMU A;  1FQI A;  3CIK A; 
#chains in the Genus database with same CATH homology
 5HE0 A;  5REQ B;  1DK8 A;  2BCJ A;  3NYN A;  2IHD A;  1FQJ B;  3PSC A;  5DO9 B;  2D9J A;  2CRP A;  1AGR E;  2JM5 A;  3UZT A;  2EBZ A;  2OWI A;  5HE1 A;  3KRX A;  3PVW A;  3NYO A;  1EZT A;  2DLV A;  5HE2 A;  1FQK B;  4TNB A;  1EZY A;  5HE3 A;  2IHB B;  1CMZ A;  3KRW A;  3C7K B;  2JNU A;  2V4Z B;  3PVU A;  4EKD B;  2AF0 A;  1OMW A;  2IK8 B;  4PNK A;  4MK0 A;  2ODE B;  2OJ4 A;  3QYF A;  2BT2 A;  2GTP C;  3V5W A;  2BV1 A;  3C7L A;  4TND A;  1EMU A;  1FQI A;  3CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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