3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
source organism Mus musculus
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
3NYNA 3V5WA 2D9JA 1FQIA 5HE3A 2BV1A 5DO9B 1FQKB 2JNUA 2OJ4A 5HE1A 2IHDA 2JM5A 2AF0A 3PVUA 3UZTA 2BCJA 4MK0A 1OMWA 2CRPA 2V4ZB 2ODEB 3KRWA 4EKDB 1EZTA 3KRXA 5HE0A 1CMZA 1DK8A 3PSCA 3CIKA 2BT2A 4PNKA 1EMUA 3PVWA 3C7KB 2OWIA 3C7LA 1EZYA 4TNBA 2IK8B 2EBZA 1AGRE 2IHBB 5HE2A 4TNDA 1FQJB 2GTPC 3NYOA 2DLVA
chains in the Genus database with same CATH superfamily
3NYNA 3V5WA 2D9JA 1FQIA 5HE3A 2BV1A 5DO9B 1FQKB 2JNUA 2OJ4A 5HE1A 2IHDA 2JM5A 2AF0A 3PVUA 3UZTA 2BCJA 4MK0A 3I5QA 1OMWA 2CRPA 2V4ZB 2ODEB 3KRWA 4HTEA 4EKDB 1EZTA 3KRXA 5HE0A 1CMZA 3QYFA 5REQB 1DK8A 3PSCA 3CIKA 2BT2A 4PNKA 1EMUA 3PVWA 3C7KB 2OWIA 3C7LA 1EZYA 4TNBA 2IK8B 2EBZA 1AGRE 2IHBB 5HE2A 4TNDA 1FQJB 2GTPC 3NYOA 2DLVA
chains in the Genus database with same CATH topology
3NYNA 3V5WA 2D9JA 1FQIA 5HE3A 2BV1A 5DO9B 1FQKB 2JNUA 2OJ4A 5HE1A 2IHDA 2JM5A 2AF0A 3PVUA 3UZTA 2BCJA 4MK0A 1OMWA 2CRPA 2V4ZB 2ODEB 3KRWA 4EKDB 1EZTA 3KRXA 5HE0A 1CMZA 3QYFA 5REQB 1DK8A 3PSCA 3CIKA 2BT2A 4PNKA 1EMUA 3PVWA 3C7KB 2OWIA 3C7LA 1EZYA 4TNBA 2IK8B 2EBZA 1AGRE 2IHBB 5HE2A 4TNDA 1FQJB 2GTPC 3NYOA 2DLVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NYN A;  3V5W A;  2D9J A;  1FQI A;  5HE3 A;  2BV1 A;  5DO9 B;  1FQK B;  2JNU A;  2OJ4 A;  5HE1 A;  2IHD A;  2JM5 A;  2AF0 A;  3PVU A;  3UZT A;  2BCJ A;  4MK0 A;  1OMW A;  2CRP A;  2V4Z B;  2ODE B;  3KRW A;  4EKD B;  1EZT A;  3KRX A;  5HE0 A;  1CMZ A;  1DK8 A;  3PSC A;  3CIK A;  2BT2 A;  4PNK A;  1EMU A;  3PVW A;  3C7K B;  2OWI A;  3C7L A;  1EZY A;  4TNB A;  2IK8 B;  2EBZ A;  1AGR E;  2IHB B;  5HE2 A;  4TND A;  1FQJ B;  2GTP C;  3NYO A;  2DLV A; 
#chains in the Genus database with same CATH topology
 3NYN A;  3V5W A;  2D9J A;  1FQI A;  5HE3 A;  2BV1 A;  5DO9 B;  1FQK B;  2JNU A;  2OJ4 A;  5HE1 A;  2IHD A;  2JM5 A;  2AF0 A;  3PVU A;  3UZT A;  2BCJ A;  4MK0 A;  3I5Q A;  1OMW A;  2CRP A;  2V4Z B;  2ODE B;  3KRW A;  4HTE A;  4EKD B;  1EZT A;  3KRX A;  5HE0 A;  1CMZ A;  3QYF A;  5REQ B;  1DK8 A;  3PSC A;  3CIK A;  2BT2 A;  4PNK A;  1EMU A;  3PVW A;  3C7K B;  2OWI A;  3C7L A;  1EZY A;  4TNB A;  2IK8 B;  2EBZ A;  1AGR E;  2IHB B;  5HE2 A;  4TND A;  1FQJ B;  2GTP C;  3NYO A;  2DLV A; 
#chains in the Genus database with same CATH homology
 3NYN A;  3V5W A;  2D9J A;  1FQI A;  5HE3 A;  2BV1 A;  5DO9 B;  1FQK B;  2JNU A;  2OJ4 A;  5HE1 A;  2IHD A;  2JM5 A;  2AF0 A;  3PVU A;  3UZT A;  2BCJ A;  4MK0 A;  1OMW A;  2CRP A;  2V4Z B;  2ODE B;  3KRW A;  4EKD B;  1EZT A;  3KRX A;  5HE0 A;  1CMZ A;  3QYF A;  5REQ B;  1DK8 A;  3PSC A;  3CIK A;  2BT2 A;  4PNK A;  1EMU A;  3PVW A;  3C7K B;  2OWI A;  3C7L A;  1EZY A;  4TNB A;  2IK8 B;  2EBZ A;  1AGR E;  2IHB B;  5HE2 A;  4TND A;  1FQJ B;  2GTP C;  3NYO A;  2DLV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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