1EZYA

High-resolution solution structure of free rgs4 by nmr
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
129
structure length
129
Chain Sequence
VSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein inhibitor
molecule keywords REGULATOR OF G-PROTEIN SIGNALING 4
publication title NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 36
structure length 129
sequence length 129
ec nomenclature
pdb deposition date 2000-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1ezyA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1ezyA01
2GTPC 3UZTA 2BV1A 4TNDA 1FQKB 3V5WA 1EZYA 2IK8B 2BCJA 1DK8A 2IHBB 3NYOA 3NYNA 1AGRE 2BT2A 2JM5A 5HE0A 1EZTA 1FQIA 2EBZA 3CIKA 3C7KB 2OJ4A 3KRXA 5HE3A 2D9JA 4TNBA 1FQJB 3PVUA 5DO9B 3C7LA 4EKDB 4PNKA 3PVWA 3PSCA 2OWIA 2JNUA 5HE1A 2AF0A 2V4ZB 2ODEB 1EMUA 2CRPA 2IHDA 4MK0A 2DLVA 5HE2A 3KRWA 1CMZA 1OMWA
chains in the Genus database with same CATH superfamily
2GTPC 3UZTA 2BV1A 4TNDA 1FQKB 3V5WA 1EZYA 2IK8B 2BCJA 1DK8A 2IHBB 3NYOA 3NYNA 1AGRE 2BT2A 2JM5A 5HE0A 1EZTA 1FQIA 2EBZA 3CIKA 3C7KB 2OJ4A 3KRXA 5HE3A 2D9JA 4HTEA 4TNBA 1FQJB 3PVUA 5DO9B 3C7LA 4EKDB 3I5QA 4PNKA 3PVWA 3PSCA 2OWIA 2JNUA 3QYFA 5HE1A 5REQB 2AF0A 2V4ZB 2ODEB 1EMUA 2CRPA 2IHDA 4MK0A 2DLVA 5HE2A 3KRWA 1CMZA 1OMWA
chains in the Genus database with same CATH topology
2GTPC 3UZTA 2BV1A 4TNDA 1FQKB 3V5WA 1EZYA 2IK8B 2BCJA 1DK8A 2IHBB 3NYOA 3NYNA 1AGRE 2BT2A 2JM5A 5HE0A 1EZTA 1FQIA 2EBZA 3CIKA 3C7KB 2OJ4A 3KRXA 5HE3A 2D9JA 4TNBA 1FQJB 3PVUA 5DO9B 3C7LA 4EKDB 4PNKA 3PVWA 3PSCA 2OWIA 2JNUA 3QYFA 5HE1A 5REQB 2AF0A 2V4ZB 2ODEB 1EMUA 2CRPA 2IHDA 4MK0A 2DLVA 5HE2A 3KRWA 1CMZA 1OMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GTP C;  3UZT A;  2BV1 A;  4TND A;  1FQK B;  3V5W A;  1EZY A;  2IK8 B;  2BCJ A;  1DK8 A;  2IHB B;  3NYO A;  3NYN A;  1AGR E;  2BT2 A;  2JM5 A;  5HE0 A;  1EZT A;  1FQI A;  2EBZ A;  3CIK A;  3C7K B;  2OJ4 A;  3KRX A;  5HE3 A;  2D9J A;  4TNB A;  1FQJ B;  3PVU A;  5DO9 B;  3C7L A;  4EKD B;  4PNK A;  3PVW A;  3PSC A;  2OWI A;  2JNU A;  5HE1 A;  2AF0 A;  2V4Z B;  2ODE B;  1EMU A;  2CRP A;  2IHD A;  4MK0 A;  2DLV A;  5HE2 A;  3KRW A;  1CMZ A;  1OMW A; 
#chains in the Genus database with same CATH topology
 2GTP C;  3UZT A;  2BV1 A;  4TND A;  1FQK B;  3V5W A;  1EZY A;  2IK8 B;  2BCJ A;  1DK8 A;  2IHB B;  3NYO A;  3NYN A;  1AGR E;  2BT2 A;  2JM5 A;  5HE0 A;  1EZT A;  1FQI A;  2EBZ A;  3CIK A;  3C7K B;  2OJ4 A;  3KRX A;  5HE3 A;  2D9J A;  4HTE A;  4TNB A;  1FQJ B;  3PVU A;  5DO9 B;  3C7L A;  4EKD B;  3I5Q A;  4PNK A;  3PVW A;  3PSC A;  2OWI A;  2JNU A;  3QYF A;  5HE1 A;  5REQ B;  2AF0 A;  2V4Z B;  2ODE B;  1EMU A;  2CRP A;  2IHD A;  4MK0 A;  2DLV A;  5HE2 A;  3KRW A;  1CMZ A;  1OMW A; 
#chains in the Genus database with same CATH homology
 2GTP C;  3UZT A;  2BV1 A;  4TND A;  1FQK B;  3V5W A;  1EZY A;  2IK8 B;  2BCJ A;  1DK8 A;  2IHB B;  3NYO A;  3NYN A;  1AGR E;  2BT2 A;  2JM5 A;  5HE0 A;  1EZT A;  1FQI A;  2EBZ A;  3CIK A;  3C7K B;  2OJ4 A;  3KRX A;  5HE3 A;  2D9J A;  4TNB A;  1FQJ B;  3PVU A;  5DO9 B;  3C7L A;  4EKD B;  4PNK A;  3PVW A;  3PSC A;  2OWI A;  2JNU A;  3QYF A;  5HE1 A;  5REQ B;  2AF0 A;  2V4Z B;  2ODE B;  1EMU A;  2CRP A;  2IHD A;  4MK0 A;  2DLV A;  5HE2 A;  3KRW A;  1CMZ A;  1OMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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