3C7LA

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
124
structure length
124
Chain Sequence
DVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 16
publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
source organism Mus musculus
total genus 50
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7lA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7lA01
1FQKB 2JM5A 5HE3A 2IHBB 2IK8B 2V4ZB 5HE1A 2CRPA 3KRXA 3PVWA 2BV1A 2BT2A 5DO9B 2JNUA 4TNDA 2EBZA 2DLVA 3KRWA 5HE2A 1FQIA 4PNKA 3PSCA 1EMUA 3C7LA 3UZTA 2AF0A 2OWIA 1AGRE 2D9JA 4MK0A 4EKDB 3PVUA 1OMWA 5HE0A 2IHDA 3CIKA 3NYOA 2BCJA 4TNBA 2ODEB 2OJ4A 3NYNA 3V5WA 3C7KB 2GTPC 1FQJB 1EZTA 1CMZA 1EZYA 1DK8A
chains in the Genus database with same CATH superfamily
1FQKB 2JM5A 5HE3A 2IHBB 2IK8B 2V4ZB 5HE1A 2CRPA 3KRXA 3PVWA 2BV1A 2BT2A 3QYFA 5DO9B 2JNUA 4TNDA 2EBZA 2DLVA 3KRWA 5HE2A 1FQIA 4HTEA 4PNKA 3PSCA 1EMUA 3C7LA 3UZTA 2AF0A 2OWIA 1AGRE 2D9JA 3I5QA 4MK0A 4EKDB 3PVUA 1OMWA 5HE0A 2IHDA 3CIKA 3NYOA 2BCJA 4TNBA 2ODEB 2OJ4A 3NYNA 3V5WA 3C7KB 5REQB 2GTPC 1FQJB 1EZTA 1CMZA 1EZYA 1DK8A
chains in the Genus database with same CATH topology
1FQKB 2JM5A 5HE3A 2IHBB 2IK8B 2V4ZB 5HE1A 2CRPA 3KRXA 3PVWA 2BV1A 2BT2A 3QYFA 5DO9B 2JNUA 4TNDA 2EBZA 2DLVA 3KRWA 5HE2A 1FQIA 4PNKA 3PSCA 1EMUA 3C7LA 3UZTA 2AF0A 2OWIA 1AGRE 2D9JA 4MK0A 4EKDB 3PVUA 1OMWA 5HE0A 2IHDA 3CIKA 3NYOA 2BCJA 4TNBA 2ODEB 2OJ4A 3NYNA 3V5WA 3C7KB 5REQB 2GTPC 1FQJB 1EZTA 1CMZA 1EZYA 1DK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQK B;  2JM5 A;  5HE3 A;  2IHB B;  2IK8 B;  2V4Z B;  5HE1 A;  2CRP A;  3KRX A;  3PVW A;  2BV1 A;  2BT2 A;  5DO9 B;  2JNU A;  4TND A;  2EBZ A;  2DLV A;  3KRW A;  5HE2 A;  1FQI A;  4PNK A;  3PSC A;  1EMU A;  3C7L A;  3UZT A;  2AF0 A;  2OWI A;  1AGR E;  2D9J A;  4MK0 A;  4EKD B;  3PVU A;  1OMW A;  5HE0 A;  2IHD A;  3CIK A;  3NYO A;  2BCJ A;  4TNB A;  2ODE B;  2OJ4 A;  3NYN A;  3V5W A;  3C7K B;  2GTP C;  1FQJ B;  1EZT A;  1CMZ A;  1EZY A;  1DK8 A; 
#chains in the Genus database with same CATH topology
 1FQK B;  2JM5 A;  5HE3 A;  2IHB B;  2IK8 B;  2V4Z B;  5HE1 A;  2CRP A;  3KRX A;  3PVW A;  2BV1 A;  2BT2 A;  3QYF A;  5DO9 B;  2JNU A;  4TND A;  2EBZ A;  2DLV A;  3KRW A;  5HE2 A;  1FQI A;  4HTE A;  4PNK A;  3PSC A;  1EMU A;  3C7L A;  3UZT A;  2AF0 A;  2OWI A;  1AGR E;  2D9J A;  3I5Q A;  4MK0 A;  4EKD B;  3PVU A;  1OMW A;  5HE0 A;  2IHD A;  3CIK A;  3NYO A;  2BCJ A;  4TNB A;  2ODE B;  2OJ4 A;  3NYN A;  3V5W A;  3C7K B;  5REQ B;  2GTP C;  1FQJ B;  1EZT A;  1CMZ A;  1EZY A;  1DK8 A; 
#chains in the Genus database with same CATH homology
 1FQK B;  2JM5 A;  5HE3 A;  2IHB B;  2IK8 B;  2V4Z B;  5HE1 A;  2CRP A;  3KRX A;  3PVW A;  2BV1 A;  2BT2 A;  3QYF A;  5DO9 B;  2JNU A;  4TND A;  2EBZ A;  2DLV A;  3KRW A;  5HE2 A;  1FQI A;  4PNK A;  3PSC A;  1EMU A;  3C7L A;  3UZT A;  2AF0 A;  2OWI A;  1AGR E;  2D9J A;  4MK0 A;  4EKD B;  3PVU A;  1OMW A;  5HE0 A;  2IHD A;  3CIK A;  3NYO A;  2BCJ A;  4TNB A;  2ODE B;  2OJ4 A;  3NYN A;  3V5W A;  3C7K B;  5REQ B;  2GTP C;  1FQJ B;  1EZT A;  1CMZ A;  1EZY A;  1DK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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