2JNUA

Solution structure of the rgs domain of human rgs14
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
136
structure length
136
Chain Sequence
SMTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 14
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 35
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2007-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jnuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jnuA01
1FQKB 3C7KB 3CIKA 2BCJA 2OWIA 2IHDA 3C7LA 3PVUA 1EZTA 2JM5A 5HE1A 4MK0A 2GTPC 2CRPA 3NYOA 1FQJB 2BV1A 2D9JA 3NYNA 3PSCA 2BT2A 3V5WA 1OMWA 2V4ZB 5HE0A 4TNDA 1AGRE 5HE2A 1EMUA 3KRXA 4PNKA 3KRWA 2EBZA 2IHBB 5HE3A 2JNUA 2ODEB 2AF0A 1FQIA 3PVWA 5DO9B 4EKDB 3UZTA 1DK8A 2IK8B 2OJ4A 1EZYA 1CMZA 4TNBA 2DLVA
chains in the Genus database with same CATH superfamily
1FQKB 3I5QA 3C7KB 3CIKA 2BCJA 2OWIA 2IHDA 3C7LA 3PVUA 1EZTA 2JM5A 5HE1A 4MK0A 2GTPC 2CRPA 4HTEA 3NYOA 1FQJB 2BV1A 2D9JA 3NYNA 3PSCA 2BT2A 3V5WA 1OMWA 2V4ZB 5HE0A 4TNDA 1AGRE 5HE2A 1EMUA 3KRXA 4PNKA 3KRWA 2EBZA 3QYFA 2IHBB 5HE3A 2JNUA 2ODEB 2AF0A 1FQIA 3PVWA 5DO9B 4EKDB 3UZTA 5REQB 1DK8A 2IK8B 2OJ4A 1EZYA 1CMZA 4TNBA 2DLVA
chains in the Genus database with same CATH topology
1FQKB 3C7KB 3CIKA 2BCJA 2OWIA 2IHDA 3C7LA 3PVUA 1EZTA 2JM5A 5HE1A 4MK0A 2GTPC 2CRPA 3NYOA 1FQJB 2BV1A 2D9JA 3NYNA 3PSCA 2BT2A 3V5WA 1OMWA 2V4ZB 5HE0A 4TNDA 1AGRE 5HE2A 1EMUA 3KRXA 4PNKA 3KRWA 2EBZA 3QYFA 2IHBB 5HE3A 2JNUA 2ODEB 2AF0A 1FQIA 3PVWA 5DO9B 4EKDB 3UZTA 5REQB 1DK8A 2IK8B 2OJ4A 1EZYA 1CMZA 4TNBA 2DLVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQK B;  3C7K B;  3CIK A;  2BCJ A;  2OWI A;  2IHD A;  3C7L A;  3PVU A;  1EZT A;  2JM5 A;  5HE1 A;  4MK0 A;  2GTP C;  2CRP A;  3NYO A;  1FQJ B;  2BV1 A;  2D9J A;  3NYN A;  3PSC A;  2BT2 A;  3V5W A;  1OMW A;  2V4Z B;  5HE0 A;  4TND A;  1AGR E;  5HE2 A;  1EMU A;  3KRX A;  4PNK A;  3KRW A;  2EBZ A;  2IHB B;  5HE3 A;  2JNU A;  2ODE B;  2AF0 A;  1FQI A;  3PVW A;  5DO9 B;  4EKD B;  3UZT A;  1DK8 A;  2IK8 B;  2OJ4 A;  1EZY A;  1CMZ A;  4TNB A;  2DLV A; 
#chains in the Genus database with same CATH topology
 1FQK B;  3I5Q A;  3C7K B;  3CIK A;  2BCJ A;  2OWI A;  2IHD A;  3C7L A;  3PVU A;  1EZT A;  2JM5 A;  5HE1 A;  4MK0 A;  2GTP C;  2CRP A;  4HTE A;  3NYO A;  1FQJ B;  2BV1 A;  2D9J A;  3NYN A;  3PSC A;  2BT2 A;  3V5W A;  1OMW A;  2V4Z B;  5HE0 A;  4TND A;  1AGR E;  5HE2 A;  1EMU A;  3KRX A;  4PNK A;  3KRW A;  2EBZ A;  3QYF A;  2IHB B;  5HE3 A;  2JNU A;  2ODE B;  2AF0 A;  1FQI A;  3PVW A;  5DO9 B;  4EKD B;  3UZT A;  5REQ B;  1DK8 A;  2IK8 B;  2OJ4 A;  1EZY A;  1CMZ A;  4TNB A;  2DLV A; 
#chains in the Genus database with same CATH homology
 1FQK B;  3C7K B;  3CIK A;  2BCJ A;  2OWI A;  2IHD A;  3C7L A;  3PVU A;  1EZT A;  2JM5 A;  5HE1 A;  4MK0 A;  2GTP C;  2CRP A;  3NYO A;  1FQJ B;  2BV1 A;  2D9J A;  3NYN A;  3PSC A;  2BT2 A;  3V5W A;  1OMW A;  2V4Z B;  5HE0 A;  4TND A;  1AGR E;  5HE2 A;  1EMU A;  3KRX A;  4PNK A;  3KRW A;  2EBZ A;  3QYF A;  2IHB B;  5HE3 A;  2JNU A;  2ODE B;  2AF0 A;  1FQI A;  3PVW A;  5DO9 B;  4EKD B;  3UZT A;  5REQ B;  1DK8 A;  2IK8 B;  2OJ4 A;  1EZY A;  1CMZ A;  4TNB A;  2DLV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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