2IK8B

Crystal structure of the heterodimeric complex of human rgs16 and activated gi alpha 1
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
120
structure length
120
Chain Sequence
SFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(i), alpha-1 subunit
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 42
structure length 120
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ik8B02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ik8B01
1EZYA 4MK0A 4PNKA 3C7KB 2BT2A 2IHDA 2OWIA 2ODEB 2V4ZB 3NYNA 3NYOA 1DK8A 5HE2A 5HE0A 3PSCA 4TNBA 2EBZA 2JM5A 2JNUA 2AF0A 5HE3A 1OMWA 3CIKA 1EZTA 5DO9B 2CRPA 3UZTA 3PVUA 1CMZA 5HE1A 3KRWA 3PVWA 4TNDA 2IK8B 4EKDB 2OJ4A 2DLVA 2BV1A 1FQJB 2BCJA 1EMUA 3V5WA 2IHBB 1FQKB 3KRXA 3C7LA 2GTPC 1AGRE 2D9JA 1FQIA
chains in the Genus database with same CATH superfamily
1EZYA 4MK0A 4PNKA 3I5QA 3QYFA 3C7KB 2BT2A 2IHDA 2OWIA 2ODEB 2V4ZB 3NYNA 3NYOA 1DK8A 5HE2A 5HE0A 3PSCA 4TNBA 2EBZA 2JM5A 2JNUA 2AF0A 5HE3A 1OMWA 3CIKA 5REQB 1EZTA 5DO9B 2CRPA 3UZTA 3PVUA 1CMZA 5HE1A 3KRWA 3PVWA 4TNDA 2IK8B 4EKDB 2OJ4A 2DLVA 2BV1A 1FQJB 2BCJA 1EMUA 3V5WA 2IHBB 1FQKB 3KRXA 3C7LA 2GTPC 1AGRE 4HTEA 2D9JA 1FQIA
chains in the Genus database with same CATH topology
1EZYA 4MK0A 4PNKA 3QYFA 3C7KB 2BT2A 2IHDA 2OWIA 2ODEB 2V4ZB 3NYNA 3NYOA 1DK8A 5HE2A 5HE0A 3PSCA 4TNBA 2EBZA 2JM5A 2JNUA 2AF0A 5HE3A 1OMWA 3CIKA 5REQB 1EZTA 5DO9B 2CRPA 3UZTA 3PVUA 1CMZA 5HE1A 3KRWA 3PVWA 4TNDA 2IK8B 4EKDB 2OJ4A 2DLVA 2BV1A 1FQJB 2BCJA 1EMUA 3V5WA 2IHBB 1FQKB 3KRXA 3C7LA 2GTPC 1AGRE 2D9JA 1FQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZY A;  4MK0 A;  4PNK A;  3C7K B;  2BT2 A;  2IHD A;  2OWI A;  2ODE B;  2V4Z B;  3NYN A;  3NYO A;  1DK8 A;  5HE2 A;  5HE0 A;  3PSC A;  4TNB A;  2EBZ A;  2JM5 A;  2JNU A;  2AF0 A;  5HE3 A;  1OMW A;  3CIK A;  1EZT A;  5DO9 B;  2CRP A;  3UZT A;  3PVU A;  1CMZ A;  5HE1 A;  3KRW A;  3PVW A;  4TND A;  2IK8 B;  4EKD B;  2OJ4 A;  2DLV A;  2BV1 A;  1FQJ B;  2BCJ A;  1EMU A;  3V5W A;  2IHB B;  1FQK B;  3KRX A;  3C7L A;  2GTP C;  1AGR E;  2D9J A;  1FQI A; 
#chains in the Genus database with same CATH topology
 1EZY A;  4MK0 A;  4PNK A;  3I5Q A;  3QYF A;  3C7K B;  2BT2 A;  2IHD A;  2OWI A;  2ODE B;  2V4Z B;  3NYN A;  3NYO A;  1DK8 A;  5HE2 A;  5HE0 A;  3PSC A;  4TNB A;  2EBZ A;  2JM5 A;  2JNU A;  2AF0 A;  5HE3 A;  1OMW A;  3CIK A;  5REQ B;  1EZT A;  5DO9 B;  2CRP A;  3UZT A;  3PVU A;  1CMZ A;  5HE1 A;  3KRW A;  3PVW A;  4TND A;  2IK8 B;  4EKD B;  2OJ4 A;  2DLV A;  2BV1 A;  1FQJ B;  2BCJ A;  1EMU A;  3V5W A;  2IHB B;  1FQK B;  3KRX A;  3C7L A;  2GTP C;  1AGR E;  4HTE A;  2D9J A;  1FQI A; 
#chains in the Genus database with same CATH homology
 1EZY A;  4MK0 A;  4PNK A;  3QYF A;  3C7K B;  2BT2 A;  2IHD A;  2OWI A;  2ODE B;  2V4Z B;  3NYN A;  3NYO A;  1DK8 A;  5HE2 A;  5HE0 A;  3PSC A;  4TNB A;  2EBZ A;  2JM5 A;  2JNU A;  2AF0 A;  5HE3 A;  1OMW A;  3CIK A;  5REQ B;  1EZT A;  5DO9 B;  2CRP A;  3UZT A;  3PVU A;  1CMZ A;  5HE1 A;  3KRW A;  3PVW A;  4TND A;  2IK8 B;  4EKD B;  2OJ4 A;  2DLV A;  2BV1 A;  1FQJ B;  2BCJ A;  1EMU A;  3V5W A;  2IHB B;  1FQK B;  3KRX A;  3C7L A;  2GTP C;  1AGR E;  2D9J A;  1FQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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