1EMUA

Structure of the axin rgs-homologous domain in complex with a samp repeat from apc
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
132
structure length
132
Chain Sequence
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords AXIN
publication title Structural basis of the Axin-adenomatous polyposis coli interaction.
pubmed doi rcsb
source organism Homo sapiens
total genus 51
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2000-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1emuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1emuA01
5HE0A 2IK8B 1FQJB 1OMWA 1EZYA 2GTPC 3PSCA 2BV1A 2AF0A 4PNKA 5HE1A 2BCJA 1FQKB 2D9JA 3C7LA 2JM5A 3V5WA 3CIKA 1EZTA 2BT2A 4TNDA 1FQIA 2V4ZB 2CRPA 2ODEB 3KRXA 5HE2A 2EBZA 2JNUA 5DO9B 2IHBB 1DK8A 1CMZA 3NYNA 4TNBA 1AGRE 2OJ4A 3NYOA 3PVUA 4MK0A 1EMUA 3C7KB 4EKDB 2OWIA 2DLVA 5HE3A 3UZTA 2IHDA 3PVWA 3KRWA
chains in the Genus database with same CATH superfamily
5HE0A 2IK8B 1FQJB 1OMWA 1EZYA 2GTPC 3I5QA 3PSCA 2BV1A 2AF0A 3QYFA 4PNKA 5HE1A 2BCJA 1FQKB 2D9JA 3C7LA 2JM5A 3V5WA 3CIKA 1EZTA 2BT2A 4TNDA 1FQIA 2V4ZB 2CRPA 2ODEB 3KRXA 4HTEA 5HE2A 2EBZA 2JNUA 5DO9B 2IHBB 1DK8A 1CMZA 3NYNA 4TNBA 1AGRE 5REQB 2OJ4A 3NYOA 3PVUA 4MK0A 1EMUA 3C7KB 4EKDB 2OWIA 2DLVA 5HE3A 3UZTA 2IHDA 3PVWA 3KRWA
chains in the Genus database with same CATH topology
5HE0A 2IK8B 1FQJB 1OMWA 1EZYA 2GTPC 3PSCA 2BV1A 2AF0A 3QYFA 4PNKA 5HE1A 2BCJA 1FQKB 2D9JA 3C7LA 2JM5A 3V5WA 3CIKA 1EZTA 2BT2A 4TNDA 1FQIA 2V4ZB 2CRPA 2ODEB 3KRXA 5HE2A 2EBZA 2JNUA 5DO9B 2IHBB 1DK8A 1CMZA 3NYNA 4TNBA 1AGRE 5REQB 2OJ4A 3NYOA 3PVUA 4MK0A 1EMUA 3C7KB 4EKDB 2OWIA 2DLVA 5HE3A 3UZTA 2IHDA 3PVWA 3KRWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE0 A;  2IK8 B;  1FQJ B;  1OMW A;  1EZY A;  2GTP C;  3PSC A;  2BV1 A;  2AF0 A;  4PNK A;  5HE1 A;  2BCJ A;  1FQK B;  2D9J A;  3C7L A;  2JM5 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  4TND A;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  3KRX A;  5HE2 A;  2EBZ A;  2JNU A;  5DO9 B;  2IHB B;  1DK8 A;  1CMZ A;  3NYN A;  4TNB A;  1AGR E;  2OJ4 A;  3NYO A;  3PVU A;  4MK0 A;  1EMU A;  3C7K B;  4EKD B;  2OWI A;  2DLV A;  5HE3 A;  3UZT A;  2IHD A;  3PVW A;  3KRW A; 
#chains in the Genus database with same CATH topology
 5HE0 A;  2IK8 B;  1FQJ B;  1OMW A;  1EZY A;  2GTP C;  3I5Q A;  3PSC A;  2BV1 A;  2AF0 A;  3QYF A;  4PNK A;  5HE1 A;  2BCJ A;  1FQK B;  2D9J A;  3C7L A;  2JM5 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  4TND A;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  3KRX A;  4HTE A;  5HE2 A;  2EBZ A;  2JNU A;  5DO9 B;  2IHB B;  1DK8 A;  1CMZ A;  3NYN A;  4TNB A;  1AGR E;  5REQ B;  2OJ4 A;  3NYO A;  3PVU A;  4MK0 A;  1EMU A;  3C7K B;  4EKD B;  2OWI A;  2DLV A;  5HE3 A;  3UZT A;  2IHD A;  3PVW A;  3KRW A; 
#chains in the Genus database with same CATH homology
 5HE0 A;  2IK8 B;  1FQJ B;  1OMW A;  1EZY A;  2GTP C;  3PSC A;  2BV1 A;  2AF0 A;  3QYF A;  4PNK A;  5HE1 A;  2BCJ A;  1FQK B;  2D9J A;  3C7L A;  2JM5 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  4TND A;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  3KRX A;  5HE2 A;  2EBZ A;  2JNU A;  5DO9 B;  2IHB B;  1DK8 A;  1CMZ A;  3NYN A;  4TNB A;  1AGR E;  5REQ B;  2OJ4 A;  3NYO A;  3PVU A;  4MK0 A;  1EMU A;  3C7K B;  4EKD B;  2OWI A;  2DLV A;  5HE3 A;  3UZT A;  2IHD A;  3PVW A;  3KRW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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