2OWIA

Solution structure of the rgs domain from human rgs18
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
134
structure length
134
Chain Sequence
SMVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 18
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 48
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2007-02-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2owiA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2owiA01
1FQKB 1DK8A 3V5WA 2ODEB 3C7LA 1EMUA 2OJ4A 3C7KB 2JM5A 1AGRE 5DO9B 2GTPC 2CRPA 1EZYA 3PSCA 2IK8B 1CMZA 1FQIA 2OWIA 4EKDB 2BV1A 2JNUA 3CIKA 3PVWA 4PNKA 2D9JA 3NYNA 5HE2A 5HE0A 3KRXA 2DLVA 3NYOA 2BCJA 4MK0A 2IHDA 1EZTA 4TNBA 4TNDA 5HE3A 3UZTA 3PVUA 2V4ZB 1OMWA 2EBZA 2AF0A 5HE1A 1FQJB 2BT2A 3KRWA 2IHBB
chains in the Genus database with same CATH superfamily
1FQKB 1DK8A 3V5WA 2ODEB 3C7LA 1EMUA 2OJ4A 3C7KB 2JM5A 1AGRE 5DO9B 2GTPC 2CRPA 1EZYA 3PSCA 2IK8B 1CMZA 1FQIA 2OWIA 4EKDB 2BV1A 2JNUA 3CIKA 3PVWA 4PNKA 3I5QA 2D9JA 3NYNA 3QYFA 5HE2A 5HE0A 3KRXA 2DLVA 3NYOA 2BCJA 4MK0A 2IHDA 5REQB 1EZTA 4TNBA 4TNDA 5HE3A 3UZTA 3PVUA 2V4ZB 1OMWA 2EBZA 2AF0A 5HE1A 4HTEA 1FQJB 2BT2A 3KRWA 2IHBB
chains in the Genus database with same CATH topology
1FQKB 1DK8A 3V5WA 2ODEB 3C7LA 1EMUA 2OJ4A 3C7KB 2JM5A 1AGRE 5DO9B 2GTPC 2CRPA 1EZYA 3PSCA 2IK8B 1CMZA 1FQIA 2OWIA 4EKDB 2BV1A 2JNUA 3CIKA 3PVWA 4PNKA 2D9JA 3NYNA 3QYFA 5HE2A 5HE0A 3KRXA 2DLVA 3NYOA 2BCJA 4MK0A 2IHDA 5REQB 1EZTA 4TNBA 4TNDA 5HE3A 3UZTA 3PVUA 2V4ZB 1OMWA 2EBZA 2AF0A 5HE1A 1FQJB 2BT2A 3KRWA 2IHBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQK B;  1DK8 A;  3V5W A;  2ODE B;  3C7L A;  1EMU A;  2OJ4 A;  3C7K B;  2JM5 A;  1AGR E;  5DO9 B;  2GTP C;  2CRP A;  1EZY A;  3PSC A;  2IK8 B;  1CMZ A;  1FQI A;  2OWI A;  4EKD B;  2BV1 A;  2JNU A;  3CIK A;  3PVW A;  4PNK A;  2D9J A;  3NYN A;  5HE2 A;  5HE0 A;  3KRX A;  2DLV A;  3NYO A;  2BCJ A;  4MK0 A;  2IHD A;  1EZT A;  4TNB A;  4TND A;  5HE3 A;  3UZT A;  3PVU A;  2V4Z B;  1OMW A;  2EBZ A;  2AF0 A;  5HE1 A;  1FQJ B;  2BT2 A;  3KRW A;  2IHB B; 
#chains in the Genus database with same CATH topology
 1FQK B;  1DK8 A;  3V5W A;  2ODE B;  3C7L A;  1EMU A;  2OJ4 A;  3C7K B;  2JM5 A;  1AGR E;  5DO9 B;  2GTP C;  2CRP A;  1EZY A;  3PSC A;  2IK8 B;  1CMZ A;  1FQI A;  2OWI A;  4EKD B;  2BV1 A;  2JNU A;  3CIK A;  3PVW A;  4PNK A;  3I5Q A;  2D9J A;  3NYN A;  3QYF A;  5HE2 A;  5HE0 A;  3KRX A;  2DLV A;  3NYO A;  2BCJ A;  4MK0 A;  2IHD A;  5REQ B;  1EZT A;  4TNB A;  4TND A;  5HE3 A;  3UZT A;  3PVU A;  2V4Z B;  1OMW A;  2EBZ A;  2AF0 A;  5HE1 A;  4HTE A;  1FQJ B;  2BT2 A;  3KRW A;  2IHB B; 
#chains in the Genus database with same CATH homology
 1FQK B;  1DK8 A;  3V5W A;  2ODE B;  3C7L A;  1EMU A;  2OJ4 A;  3C7K B;  2JM5 A;  1AGR E;  5DO9 B;  2GTP C;  2CRP A;  1EZY A;  3PSC A;  2IK8 B;  1CMZ A;  1FQI A;  2OWI A;  4EKD B;  2BV1 A;  2JNU A;  3CIK A;  3PVW A;  4PNK A;  2D9J A;  3NYN A;  3QYF A;  5HE2 A;  5HE0 A;  3KRX A;  2DLV A;  3NYO A;  2BCJ A;  4MK0 A;  2IHD A;  5REQ B;  1EZT A;  4TNB A;  4TND A;  5HE3 A;  3UZT A;  3PVU A;  2V4Z B;  1OMW A;  2EBZ A;  2AF0 A;  5HE1 A;  1FQJ B;  2BT2 A;  3KRW A;  2IHB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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