2DLVA

Solution structure of the rgs domain of human regulator of g-protein signaling 18
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
140
structure length
140
Chain Sequence
GSSGSSGSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 18
publication title Solution structure of the RGS domain of human regulator of G-protein signaling 18
rcsb
source organism Homo sapiens
total genus 34
structure length 140
sequence length 140
ec nomenclature
pdb deposition date 2006-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2dlvA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2dlvA01
2OWIA 5HE1A 4EKDB 2OJ4A 4TNDA 1EZTA 1FQJB 2AF0A 3C7LA 3NYNA 3V5WA 2GTPC 2JM5A 2ODEB 1DK8A 3C7KB 5DO9B 2JNUA 4MK0A 3PVWA 2V4ZB 2DLVA 1EZYA 2BT2A 2BCJA 4PNKA 1AGRE 3PVUA 1OMWA 3KRWA 3NYOA 5HE2A 5HE3A 3UZTA 2EBZA 1EMUA 2IHDA 2BV1A 2IK8B 3CIKA 2IHBB 1FQIA 3KRXA 2D9JA 4TNBA 5HE0A 2CRPA 1CMZA 3PSCA 1FQKB
chains in the Genus database with same CATH superfamily
3I5QA 2OWIA 5HE1A 4EKDB 2OJ4A 4TNDA 1EZTA 1FQJB 2AF0A 3QYFA 3C7LA 3NYNA 3V5WA 2GTPC 2JM5A 2ODEB 1DK8A 3C7KB 5DO9B 2JNUA 4MK0A 3PVWA 2V4ZB 2DLVA 1EZYA 2BT2A 2BCJA 4PNKA 4HTEA 1AGRE 3PVUA 1OMWA 3KRWA 3NYOA 5HE2A 5HE3A 3UZTA 2EBZA 1EMUA 2IHDA 2BV1A 2IK8B 3CIKA 2IHBB 5REQB 1FQIA 3KRXA 2D9JA 4TNBA 5HE0A 2CRPA 1CMZA 3PSCA 1FQKB
chains in the Genus database with same CATH topology
2OWIA 5HE1A 4EKDB 2OJ4A 4TNDA 1EZTA 1FQJB 2AF0A 3QYFA 3C7LA 3NYNA 3V5WA 2GTPC 2JM5A 2ODEB 1DK8A 3C7KB 5DO9B 2JNUA 4MK0A 3PVWA 2V4ZB 2DLVA 1EZYA 2BT2A 2BCJA 4PNKA 1AGRE 3PVUA 1OMWA 3KRWA 3NYOA 5HE2A 5HE3A 3UZTA 2EBZA 1EMUA 2IHDA 2BV1A 2IK8B 3CIKA 2IHBB 5REQB 1FQIA 3KRXA 2D9JA 4TNBA 5HE0A 2CRPA 1CMZA 3PSCA 1FQKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OWI A;  5HE1 A;  4EKD B;  2OJ4 A;  4TND A;  1EZT A;  1FQJ B;  2AF0 A;  3C7L A;  3NYN A;  3V5W A;  2GTP C;  2JM5 A;  2ODE B;  1DK8 A;  3C7K B;  5DO9 B;  2JNU A;  4MK0 A;  3PVW A;  2V4Z B;  2DLV A;  1EZY A;  2BT2 A;  2BCJ A;  4PNK A;  1AGR E;  3PVU A;  1OMW A;  3KRW A;  3NYO A;  5HE2 A;  5HE3 A;  3UZT A;  2EBZ A;  1EMU A;  2IHD A;  2BV1 A;  2IK8 B;  3CIK A;  2IHB B;  1FQI A;  3KRX A;  2D9J A;  4TNB A;  5HE0 A;  2CRP A;  1CMZ A;  3PSC A;  1FQK B; 
#chains in the Genus database with same CATH topology
 3I5Q A;  2OWI A;  5HE1 A;  4EKD B;  2OJ4 A;  4TND A;  1EZT A;  1FQJ B;  2AF0 A;  3QYF A;  3C7L A;  3NYN A;  3V5W A;  2GTP C;  2JM5 A;  2ODE B;  1DK8 A;  3C7K B;  5DO9 B;  2JNU A;  4MK0 A;  3PVW A;  2V4Z B;  2DLV A;  1EZY A;  2BT2 A;  2BCJ A;  4PNK A;  4HTE A;  1AGR E;  3PVU A;  1OMW A;  3KRW A;  3NYO A;  5HE2 A;  5HE3 A;  3UZT A;  2EBZ A;  1EMU A;  2IHD A;  2BV1 A;  2IK8 B;  3CIK A;  2IHB B;  5REQ B;  1FQI A;  3KRX A;  2D9J A;  4TNB A;  5HE0 A;  2CRP A;  1CMZ A;  3PSC A;  1FQK B; 
#chains in the Genus database with same CATH homology
 2OWI A;  5HE1 A;  4EKD B;  2OJ4 A;  4TND A;  1EZT A;  1FQJ B;  2AF0 A;  3QYF A;  3C7L A;  3NYN A;  3V5W A;  2GTP C;  2JM5 A;  2ODE B;  1DK8 A;  3C7K B;  5DO9 B;  2JNU A;  4MK0 A;  3PVW A;  2V4Z B;  2DLV A;  1EZY A;  2BT2 A;  2BCJ A;  4PNK A;  1AGR E;  3PVU A;  1OMW A;  3KRW A;  3NYO A;  5HE2 A;  5HE3 A;  3UZT A;  2EBZ A;  1EMU A;  2IHD A;  2BV1 A;  2IK8 B;  3CIK A;  2IHB B;  5REQ B;  1FQI A;  3KRX A;  2D9J A;  4TNB A;  5HE0 A;  2CRP A;  1CMZ A;  3PSC A;  1FQK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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