2ODEB

Crystal structure of the heterodimeric complex of human rgs8 and activated gi alpha 3
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
131
structure length
131
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(k) subunit alpha
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 53
structure length 131
sequence length 131
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2odeB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2odeB01
2OJ4A 4EKDB 5HE2A 3UZTA 2IK8B 1FQKB 4MK0A 2GTPC 2IHDA 2JNUA 1DK8A 3PVWA 5HE1A 5HE3A 4TNDA 2AF0A 2CRPA 3NYNA 4TNBA 3V5WA 1EMUA 1EZTA 5DO9B 3KRXA 3PVUA 2DLVA 3KRWA 1OMWA 2JM5A 1FQIA 3PSCA 2ODEB 2IHBB 2BT2A 4PNKA 1EZYA 2EBZA 2D9JA 2OWIA 1CMZA 5HE0A 2BV1A 1FQJB 2BCJA 3C7LA 3CIKA 3NYOA 2V4ZB 1AGRE 3C7KB
chains in the Genus database with same CATH superfamily
2OJ4A 4EKDB 5HE2A 3UZTA 2IK8B 1FQKB 4MK0A 2GTPC 2IHDA 2JNUA 1DK8A 3I5QA 3PVWA 4HTEA 5HE1A 5HE3A 4TNDA 2AF0A 2CRPA 3NYNA 4TNBA 3V5WA 1EMUA 1EZTA 5DO9B 3KRXA 3PVUA 2DLVA 3KRWA 1OMWA 2JM5A 1FQIA 3PSCA 2ODEB 5REQB 2IHBB 2BT2A 4PNKA 1EZYA 2EBZA 2D9JA 2OWIA 1CMZA 3QYFA 5HE0A 2BV1A 1FQJB 2BCJA 3C7LA 3CIKA 3NYOA 2V4ZB 1AGRE 3C7KB
chains in the Genus database with same CATH topology
2OJ4A 4EKDB 5HE2A 3UZTA 2IK8B 1FQKB 4MK0A 2GTPC 2IHDA 2JNUA 1DK8A 3PVWA 5HE1A 5HE3A 4TNDA 2AF0A 2CRPA 3NYNA 4TNBA 3V5WA 1EMUA 1EZTA 5DO9B 3KRXA 3PVUA 2DLVA 3KRWA 1OMWA 2JM5A 1FQIA 3PSCA 2ODEB 5REQB 2IHBB 2BT2A 4PNKA 1EZYA 2EBZA 2D9JA 2OWIA 1CMZA 3QYFA 5HE0A 2BV1A 1FQJB 2BCJA 3C7LA 3CIKA 3NYOA 2V4ZB 1AGRE 3C7KB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OJ4 A;  4EKD B;  5HE2 A;  3UZT A;  2IK8 B;  1FQK B;  4MK0 A;  2GTP C;  2IHD A;  2JNU A;  1DK8 A;  3PVW A;  5HE1 A;  5HE3 A;  4TND A;  2AF0 A;  2CRP A;  3NYN A;  4TNB A;  3V5W A;  1EMU A;  1EZT A;  5DO9 B;  3KRX A;  3PVU A;  2DLV A;  3KRW A;  1OMW A;  2JM5 A;  1FQI A;  3PSC A;  2ODE B;  2IHB B;  2BT2 A;  4PNK A;  1EZY A;  2EBZ A;  2D9J A;  2OWI A;  1CMZ A;  5HE0 A;  2BV1 A;  1FQJ B;  2BCJ A;  3C7L A;  3CIK A;  3NYO A;  2V4Z B;  1AGR E;  3C7K B; 
#chains in the Genus database with same CATH topology
 2OJ4 A;  4EKD B;  5HE2 A;  3UZT A;  2IK8 B;  1FQK B;  4MK0 A;  2GTP C;  2IHD A;  2JNU A;  1DK8 A;  3I5Q A;  3PVW A;  4HTE A;  5HE1 A;  5HE3 A;  4TND A;  2AF0 A;  2CRP A;  3NYN A;  4TNB A;  3V5W A;  1EMU A;  1EZT A;  5DO9 B;  3KRX A;  3PVU A;  2DLV A;  3KRW A;  1OMW A;  2JM5 A;  1FQI A;  3PSC A;  2ODE B;  5REQ B;  2IHB B;  2BT2 A;  4PNK A;  1EZY A;  2EBZ A;  2D9J A;  2OWI A;  1CMZ A;  3QYF A;  5HE0 A;  2BV1 A;  1FQJ B;  2BCJ A;  3C7L A;  3CIK A;  3NYO A;  2V4Z B;  1AGR E;  3C7K B; 
#chains in the Genus database with same CATH homology
 2OJ4 A;  4EKD B;  5HE2 A;  3UZT A;  2IK8 B;  1FQK B;  4MK0 A;  2GTP C;  2IHD A;  2JNU A;  1DK8 A;  3PVW A;  5HE1 A;  5HE3 A;  4TND A;  2AF0 A;  2CRP A;  3NYN A;  4TNB A;  3V5W A;  1EMU A;  1EZT A;  5DO9 B;  3KRX A;  3PVU A;  2DLV A;  3KRW A;  1OMW A;  2JM5 A;  1FQI A;  3PSC A;  2ODE B;  5REQ B;  2IHB B;  2BT2 A;  4PNK A;  1EZY A;  2EBZ A;  2D9J A;  2OWI A;  1CMZ A;  3QYF A;  5HE0 A;  2BV1 A;  1FQJ B;  2BCJ A;  3C7L A;  3CIK A;  3NYO A;  2V4Z B;  1AGR E;  3C7K B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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