1FQJB

Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
133
structure length
133
Chain Sequence
DIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
source organism Bos taurus
total genus 50
structure length 133
sequence length 133
chains with identical sequence E
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqjB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqjB01
1FQIA 1FQJB 2JM5A 1EZYA 1EMUA 2IHDA 2IHBB 2AF0A 3NYNA 5HE0A 3C7KB 2ODEB 4TNDA 5HE1A 3NYOA 2CRPA 4EKDB 3C7LA 5HE2A 2OJ4A 3PVWA 1OMWA 2BCJA 2DLVA 2BV1A 2BT2A 3V5WA 2OWIA 4MK0A 3UZTA 5HE3A 1DK8A 5DO9B 2GTPC 3KRWA 1FQKB 1AGRE 2IK8B 1CMZA 2EBZA 3PSCA 2V4ZB 2D9JA 3PVUA 4PNKA 3CIKA 4TNBA 2JNUA 3KRXA 1EZTA
chains in the Genus database with same CATH superfamily
1FQIA 1FQJB 5REQB 2JM5A 1EZYA 1EMUA 2IHDA 2IHBB 2AF0A 3NYNA 3I5QA 3C7KB 2ODEB 4TNDA 5HE0A 3NYOA 2CRPA 5HE1A 4EKDB 3C7LA 5HE2A 2OJ4A 4HTEA 3QYFA 3PVWA 1OMWA 2BCJA 2DLVA 2BV1A 2BT2A 3V5WA 2OWIA 4MK0A 3UZTA 5HE3A 1DK8A 5DO9B 2GTPC 3KRWA 1FQKB 1AGRE 2IK8B 1CMZA 2EBZA 3PSCA 2V4ZB 2D9JA 3PVUA 4PNKA 3CIKA 4TNBA 2JNUA 3KRXA 1EZTA
chains in the Genus database with same CATH topology
1FQIA 1FQJB 5REQB 2JM5A 1EZYA 1EMUA 2IHDA 2IHBB 2AF0A 3NYNA 5HE0A 3C7KB 2ODEB 4TNDA 5HE1A 3NYOA 2CRPA 4EKDB 3C7LA 5HE2A 2OJ4A 3QYFA 3PVWA 1OMWA 2BCJA 2DLVA 2BV1A 2BT2A 3V5WA 2OWIA 4MK0A 3UZTA 5HE3A 1DK8A 5DO9B 2GTPC 3KRWA 1FQKB 1AGRE 2IK8B 1CMZA 2EBZA 3PSCA 2V4ZB 2D9JA 3PVUA 4PNKA 3CIKA 4TNBA 2JNUA 3KRXA 1EZTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQI A;  1FQJ B;  2JM5 A;  1EZY A;  1EMU A;  2IHD A;  2IHB B;  2AF0 A;  3NYN A;  5HE0 A;  3C7K B;  2ODE B;  4TND A;  5HE1 A;  3NYO A;  2CRP A;  4EKD B;  3C7L A;  5HE2 A;  2OJ4 A;  3PVW A;  1OMW A;  2BCJ A;  2DLV A;  2BV1 A;  2BT2 A;  3V5W A;  2OWI A;  4MK0 A;  3UZT A;  5HE3 A;  1DK8 A;  5DO9 B;  2GTP C;  3KRW A;  1FQK B;  1AGR E;  2IK8 B;  1CMZ A;  2EBZ A;  3PSC A;  2V4Z B;  2D9J A;  3PVU A;  4PNK A;  3CIK A;  4TNB A;  2JNU A;  3KRX A;  1EZT A; 
#chains in the Genus database with same CATH topology
 1FQI A;  1FQJ B;  5REQ B;  2JM5 A;  1EZY A;  1EMU A;  2IHD A;  2IHB B;  2AF0 A;  3NYN A;  3I5Q A;  3C7K B;  2ODE B;  4TND A;  5HE0 A;  3NYO A;  2CRP A;  5HE1 A;  4EKD B;  3C7L A;  5HE2 A;  2OJ4 A;  4HTE A;  3QYF A;  3PVW A;  1OMW A;  2BCJ A;  2DLV A;  2BV1 A;  2BT2 A;  3V5W A;  2OWI A;  4MK0 A;  3UZT A;  5HE3 A;  1DK8 A;  5DO9 B;  2GTP C;  3KRW A;  1FQK B;  1AGR E;  2IK8 B;  1CMZ A;  2EBZ A;  3PSC A;  2V4Z B;  2D9J A;  3PVU A;  4PNK A;  3CIK A;  4TNB A;  2JNU A;  3KRX A;  1EZT A; 
#chains in the Genus database with same CATH homology
 1FQI A;  1FQJ B;  5REQ B;  2JM5 A;  1EZY A;  1EMU A;  2IHD A;  2IHB B;  2AF0 A;  3NYN A;  5HE0 A;  3C7K B;  2ODE B;  4TND A;  5HE1 A;  3NYO A;  2CRP A;  4EKD B;  3C7L A;  5HE2 A;  2OJ4 A;  3QYF A;  3PVW A;  1OMW A;  2BCJ A;  2DLV A;  2BV1 A;  2BT2 A;  3V5W A;  2OWI A;  4MK0 A;  3UZT A;  5HE3 A;  1DK8 A;  5DO9 B;  2GTP C;  3KRW A;  1FQK B;  1AGR E;  2IK8 B;  1CMZ A;  2EBZ A;  3PSC A;  2V4Z B;  2D9J A;  3PVU A;  4PNK A;  3CIK A;  4TNB A;  2JNU A;  3KRX A;  1EZT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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