2EBZA

Solution structure of the rgs domain from human regulator of g-protein signaling 12 (rgs12)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
155
structure length
155
Chain Sequence
GSSGSSGRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Regulator of G-protein signaling 12
publication title Solution structure of the RGS domain from human Regulator of G-protein signaling 12 (RGS12)
rcsb
source organism Homo sapiens
total genus 33
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2007-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ebzA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ebzA01
1FQIA 3NYOA 1EZYA 3C7LA 2ODEB 3CIKA 5HE1A 3KRXA 2OJ4A 1AGRE 2BV1A 2AF0A 4TNBA 2DLVA 2V4ZB 5DO9B 3UZTA 3PVWA 2BT2A 3PVUA 2OWIA 2EBZA 5HE0A 2IHDA 5HE3A 1CMZA 3PSCA 3C7KB 1EZTA 2JNUA 1FQJB 3NYNA 4EKDB 2BCJA 2D9JA 2IHBB 2IK8B 4TNDA 3V5WA 4MK0A 2CRPA 2JM5A 2GTPC 5HE2A 1OMWA 4PNKA 1FQKB 3KRWA 1EMUA 1DK8A
chains in the Genus database with same CATH superfamily
1FQIA 4HTEA 3NYOA 1EZYA 3C7LA 5REQB 2ODEB 3CIKA 5HE1A 3KRXA 2OJ4A 1AGRE 2BV1A 2AF0A 4TNBA 2DLVA 2V4ZB 5DO9B 3UZTA 3PVWA 2BT2A 3PVUA 2OWIA 2EBZA 5HE0A 2IHDA 5HE3A 1CMZA 3PSCA 3C7KB 1EZTA 2JNUA 1FQJB 3NYNA 4EKDB 2BCJA 3QYFA 2D9JA 2IHBB 3I5QA 2IK8B 4TNDA 3V5WA 4MK0A 2CRPA 2JM5A 2GTPC 5HE2A 1OMWA 4PNKA 1FQKB 3KRWA 1EMUA 1DK8A
chains in the Genus database with same CATH topology
1FQIA 3NYOA 1EZYA 3C7LA 5REQB 2ODEB 3CIKA 5HE1A 3KRXA 2OJ4A 1AGRE 2BV1A 2AF0A 4TNBA 2DLVA 2V4ZB 5DO9B 3UZTA 3PVWA 2BT2A 3PVUA 2OWIA 2EBZA 5HE0A 2IHDA 5HE3A 1CMZA 3PSCA 3C7KB 1EZTA 2JNUA 1FQJB 3NYNA 4EKDB 2BCJA 3QYFA 2D9JA 2IHBB 2IK8B 4TNDA 3V5WA 4MK0A 2CRPA 2JM5A 2GTPC 5HE2A 1OMWA 4PNKA 1FQKB 3KRWA 1EMUA 1DK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FQI A;  3NYO A;  1EZY A;  3C7L A;  2ODE B;  3CIK A;  5HE1 A;  3KRX A;  2OJ4 A;  1AGR E;  2BV1 A;  2AF0 A;  4TNB A;  2DLV A;  2V4Z B;  5DO9 B;  3UZT A;  3PVW A;  2BT2 A;  3PVU A;  2OWI A;  2EBZ A;  5HE0 A;  2IHD A;  5HE3 A;  1CMZ A;  3PSC A;  3C7K B;  1EZT A;  2JNU A;  1FQJ B;  3NYN A;  4EKD B;  2BCJ A;  2D9J A;  2IHB B;  2IK8 B;  4TND A;  3V5W A;  4MK0 A;  2CRP A;  2JM5 A;  2GTP C;  5HE2 A;  1OMW A;  4PNK A;  1FQK B;  3KRW A;  1EMU A;  1DK8 A; 
#chains in the Genus database with same CATH topology
 1FQI A;  4HTE A;  3NYO A;  1EZY A;  3C7L A;  5REQ B;  2ODE B;  3CIK A;  5HE1 A;  3KRX A;  2OJ4 A;  1AGR E;  2BV1 A;  2AF0 A;  4TNB A;  2DLV A;  2V4Z B;  5DO9 B;  3UZT A;  3PVW A;  2BT2 A;  3PVU A;  2OWI A;  2EBZ A;  5HE0 A;  2IHD A;  5HE3 A;  1CMZ A;  3PSC A;  3C7K B;  1EZT A;  2JNU A;  1FQJ B;  3NYN A;  4EKD B;  2BCJ A;  3QYF A;  2D9J A;  2IHB B;  3I5Q A;  2IK8 B;  4TND A;  3V5W A;  4MK0 A;  2CRP A;  2JM5 A;  2GTP C;  5HE2 A;  1OMW A;  4PNK A;  1FQK B;  3KRW A;  1EMU A;  1DK8 A; 
#chains in the Genus database with same CATH homology
 1FQI A;  3NYO A;  1EZY A;  3C7L A;  5REQ B;  2ODE B;  3CIK A;  5HE1 A;  3KRX A;  2OJ4 A;  1AGR E;  2BV1 A;  2AF0 A;  4TNB A;  2DLV A;  2V4Z B;  5DO9 B;  3UZT A;  3PVW A;  2BT2 A;  3PVU A;  2OWI A;  2EBZ A;  5HE0 A;  2IHD A;  5HE3 A;  1CMZ A;  3PSC A;  3C7K B;  1EZT A;  2JNU A;  1FQJ B;  3NYN A;  4EKD B;  2BCJ A;  3QYF A;  2D9J A;  2IHB B;  2IK8 B;  4TND A;  3V5W A;  4MK0 A;  2CRP A;  2JM5 A;  2GTP C;  5HE2 A;  1OMW A;  4PNK A;  1FQK B;  3KRW A;  1EMU A;  1DK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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