1FQKB

Crystal structure of the heterodimeric complex of the rgs domain of rgs9, and the gt/i1 chimera alpha subunit [(rgs9)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)]
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
136
structure length
136
Chain Sequence
LVDIPTKMRVERWAFNFSELIRDPKGRQSFQHFLRKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(t) subunit alpha-1,Guan
publication title Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
pubmed doi rcsb
source organism Bos taurus
total genus 49
structure length 136
sequence length 136
chains with identical sequence D
ec nomenclature
pdb deposition date 2000-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 1fqkB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 1fqkB01
2CRPA 1FQJB 2BT2A 1EMUA 2BV1A 5HE3A 5HE2A 5HE0A 1EZYA 2EBZA 1EZTA 3KRWA 2IHDA 4PNKA 1FQIA 5DO9B 1DK8A 4EKDB 4TNBA 3NYOA 1OMWA 2JM5A 2BCJA 3CIKA 3KRXA 3UZTA 3C7LA 3PSCA 2DLVA 4MK0A 2D9JA 2IHBB 2OWIA 4TNDA 2JNUA 2V4ZB 1AGRE 1FQKB 3V5WA 3PVWA 3NYNA 2AF0A 2OJ4A 5HE1A 3C7KB 3PVUA 1CMZA 2GTPC 2ODEB 2IK8B
chains in the Genus database with same CATH superfamily
2CRPA 1FQJB 2BT2A 1EMUA 2BV1A 5HE3A 5HE2A 5HE0A 1EZYA 2EBZA 1EZTA 3KRWA 2IHDA 4PNKA 1FQIA 3I5QA 5DO9B 1DK8A 4HTEA 4EKDB 4TNBA 3NYOA 1OMWA 2JM5A 2BCJA 3CIKA 3KRXA 3UZTA 3C7LA 3PSCA 5REQB 2DLVA 4MK0A 2D9JA 2IHBB 2OWIA 4TNDA 3QYFA 2JNUA 2V4ZB 1AGRE 1FQKB 3V5WA 3PVWA 3NYNA 2AF0A 2OJ4A 5HE1A 3C7KB 3PVUA 1CMZA 2GTPC 2ODEB 2IK8B
chains in the Genus database with same CATH topology
2CRPA 1FQJB 2BT2A 1EMUA 2BV1A 5HE3A 5HE2A 5HE0A 1EZYA 2EBZA 1EZTA 3KRWA 2IHDA 4PNKA 1FQIA 5DO9B 1DK8A 4EKDB 4TNBA 3NYOA 1OMWA 2JM5A 2BCJA 3CIKA 3KRXA 3UZTA 3C7LA 3PSCA 5REQB 2DLVA 4MK0A 2D9JA 2IHBB 2OWIA 4TNDA 3QYFA 2JNUA 2V4ZB 1AGRE 1FQKB 3V5WA 3PVWA 3NYNA 2AF0A 2OJ4A 5HE1A 3C7KB 3PVUA 1CMZA 2GTPC 2ODEB 2IK8B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CRP A;  1FQJ B;  2BT2 A;  1EMU A;  2BV1 A;  5HE3 A;  5HE2 A;  5HE0 A;  1EZY A;  2EBZ A;  1EZT A;  3KRW A;  2IHD A;  4PNK A;  1FQI A;  5DO9 B;  1DK8 A;  4EKD B;  4TNB A;  3NYO A;  1OMW A;  2JM5 A;  2BCJ A;  3CIK A;  3KRX A;  3UZT A;  3C7L A;  3PSC A;  2DLV A;  4MK0 A;  2D9J A;  2IHB B;  2OWI A;  4TND A;  2JNU A;  2V4Z B;  1AGR E;  1FQK B;  3V5W A;  3PVW A;  3NYN A;  2AF0 A;  2OJ4 A;  5HE1 A;  3C7K B;  3PVU A;  1CMZ A;  2GTP C;  2ODE B;  2IK8 B; 
#chains in the Genus database with same CATH topology
 2CRP A;  1FQJ B;  2BT2 A;  1EMU A;  2BV1 A;  5HE3 A;  5HE2 A;  5HE0 A;  1EZY A;  2EBZ A;  1EZT A;  3KRW A;  2IHD A;  4PNK A;  1FQI A;  3I5Q A;  5DO9 B;  1DK8 A;  4HTE A;  4EKD B;  4TNB A;  3NYO A;  1OMW A;  2JM5 A;  2BCJ A;  3CIK A;  3KRX A;  3UZT A;  3C7L A;  3PSC A;  5REQ B;  2DLV A;  4MK0 A;  2D9J A;  2IHB B;  2OWI A;  4TND A;  3QYF A;  2JNU A;  2V4Z B;  1AGR E;  1FQK B;  3V5W A;  3PVW A;  3NYN A;  2AF0 A;  2OJ4 A;  5HE1 A;  3C7K B;  3PVU A;  1CMZ A;  2GTP C;  2ODE B;  2IK8 B; 
#chains in the Genus database with same CATH homology
 2CRP A;  1FQJ B;  2BT2 A;  1EMU A;  2BV1 A;  5HE3 A;  5HE2 A;  5HE0 A;  1EZY A;  2EBZ A;  1EZT A;  3KRW A;  2IHD A;  4PNK A;  1FQI A;  5DO9 B;  1DK8 A;  4EKD B;  4TNB A;  3NYO A;  1OMW A;  2JM5 A;  2BCJ A;  3CIK A;  3KRX A;  3UZT A;  3C7L A;  3PSC A;  5REQ B;  2DLV A;  4MK0 A;  2D9J A;  2IHB B;  2OWI A;  4TND A;  3QYF A;  2JNU A;  2V4Z B;  1AGR E;  1FQK B;  3V5W A;  3PVW A;  3NYN A;  2AF0 A;  2OJ4 A;  5HE1 A;  3C7K B;  3PVU A;  1CMZ A;  2GTP C;  2ODE B;  2IK8 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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