|
46
|
159
|
4eizA |
Structure of nb113 bound to apodhfr |
|
108
|
608
|
4eckA |
Crystal structure of the toxoplasma gondii ts-dhfr |
|
42
|
166
|
4elfA |
Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase |
|
44
|
159
|
4ej1A |
Binding of nb113 camelid antibody fragment with the binary dhfr:folate complex |
|
182
|
606
|
4dp3A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p218 and nadph |
|
44
|
166
|
4eleA |
Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase |
|
174
|
605
|
4dpdA |
Wild type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts), dhf complex, nadp+, dump |
|
40
|
166
|
4elgA |
Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase |
|
42
|
159
|
4eigA |
Ca1698 camel antibody fragment in complex with dhfr |
|
41
|
166
|
4elhA |
Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase |
|
173
|
606
|
4dphA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with p65 and nadph |
|
40
|
166
|
4elbA |
Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase |
|
43
|
159
|
4dfrA |
Crystal structures of escherichia coli and lactobacillus casei dihydrofolate reductase refined at 1.7 angstroms resolution. i. general features and binding of methotrexate |
|
56
|
186
|
4ddrA |
Human dihydrofolate reductase complexed with nadph and p218 |
|
56
|
202
|
4cd2A |
Ligand induced conformational changes in the crystal structures of pneumocystis carinii dihydrofolate reductase complexes with folate and nadp+ |
|
46
|
183
|
3vcoA |
Schistosoma mansoni dihydrofolate reductase |
|
168
|
608
|
3um6A |
Double mutant (a16v+s108t) plasmodium falciparum dhfr-ts (t9/94) complexed with cycloguanil, nadph and dump |
|
177
|
608
|
3um5A |
Double mutant (a16v+s108t) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts-t9/94) complexed with pyrimethamine, nadph, and dump |
|
43
|
160
|
3tqaA |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with nadph |
|
41
|
160
|
3tq9A |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with methotrexate |
|
37
|
160
|
3tqbA |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with folate |
|
44
|
173
|
3tq8A |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with trimethoprim |
|
56
|
202
|
3td8A |
Structural analysis of pneumocystis carinii dihydrofolate reductase complex with nadph and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine |
|
40
|
157
|
3srrX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3sruX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
43
|
157
|
3srqX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
42
|
157
|
3srsX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
40
|
157
|
3sr5X |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3srwX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3sqyX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3sh2A |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (ucp120j) |
|
40
|
157
|
3sgyA |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006) |
|
53
|
186
|
3s7aA |
Human dihydrofolate reductase binary complex with pt684 |
|
52
|
186
|
3s3vA |
Human dihydrofolate reductase q35k/n64f double mutant binary complex with trimethoprim |
|
62
|
225
|
3roaA |
Candida glabrata dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(morpholin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1004) |
|
59
|
225
|
3ro9A |
Candida glabrata dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006) |
|
58
|
218
|
3rg9A |
Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210 |
|
41
|
159
|
5w3qA |
L28f e.coli dhfr in complex with nadph |
|
41
|
161
|
5ujfA |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound p218 inhibitor |
|
43
|
160
|
5uioA |
Structure of dhfr with bound dap, p-abg and nadp |
|
44
|
159
|
5ujxA |
Crystal structure of dhfr in 20% isopropanol |
|
42
|
159
|
5uihA |
Structure of dhfr with bound phenformin and nadp |
|
41
|
166
|
5u26A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p218 inhibitor |
|
42
|
166
|
5u27A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p65 inhibitor |
|
160
|
513
|
5t7oA |
Crystal structure of trypanosoma cruzi dihydrofolate reductase-thymidylate synthase in complex with (6s)-5,6,7,8-tetrahydrofolate |
|
40
|
157
|
5hf0X |
Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106) |
|
52
|
186
|
5ht4A |
6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl) |
|
42
|
157
|
5hf2X |
Staphylococcus aureus dihydrofolate reductase complexed with cyclized alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1175) |
|
45
|
159
|
5e8qA |
Crystal structure of dhfr in 20% isopropanol |
|
47
|
157
|
5ecxA |
Klebsiella pneumoniae dfra1 complexed with nadph and 6-ethyl-5-(3-(6-(pyridin-4-yl)benzo[d][1,3]dioxol-4-yl)but-1-yn-1-yl)pyrimidine-2,4-diamine |
