|
17
|
99
|
4q1yA |
Mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance |
|
19
|
99
|
4qgiA |
X-ray crystal structure of hiv-1 protease variant g48t/l89m in complex with saquinavir |
|
15
|
99
|
4phvA |
X-ray crystal structure of the hiv protease complex with l-700,417, an inhibitor with pseudo c2 symmetry |
|
18
|
99
|
4q1wA |
Mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance |
|
18
|
99
|
4q1xA |
Mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance |
|
46
|
203
|
4q5mA |
D30n tethered hiv-1 protease dimer/saquinavir complex |
|
18
|
99
|
4nptA |
Crystal structure of hiv-1 protease multiple mutant p51 complexed with darunavir |
|
16
|
99
|
4obgA |
Crystal structure of nelfinavir-resistant, inactive hiv-1 protease (d30n/n88d) in complex with the p1-p6 substrate. |
|
18
|
99
|
4obhA |
Crystal structure of inactive hiv-1 protease in complex with the p1-p6 substrate variant (l449f) |
|
18
|
99
|
4npuA |
Crystal structure of hiv-1 protease multiple mutant p51 |
|
18
|
99
|
4njtA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with darunavir |
|
18
|
99
|
4obkA |
Crystal structure of inactive hiv-1 protease in complex with the p1-p6 substrate variant (l449f/s451n) |
|
16
|
99
|
4obdA |
Crystal structure of nelfinavir-resistant, inactive hiv-1 protease (d30n/n88d) in complex with the p1-p6 substrate variant (l449f/s451n) |
|
17
|
99
|
4njvA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with ritonavir |
|
17
|
99
|
4obfA |
Crystal structure of nelfinavir-resistant, inactive hiv-1 protease variant (d30n/n88d) in complex with the p1-p6 substrate variant (s451n) |
|
16
|
99
|
4njuA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with tipranavir |
|
18
|
99
|
4njsA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with non-peptidic inhibitor, grl008 |
|
17
|
99
|
4nkkA |
Crystal structure of a multi-drug resistant clinical isolate-769 hiv-1 protease variant that is resistant to the dimerization inhibitory activity of tlf-paff |
|
18
|
99
|
4objA |
Crystal structure of inactive hiv-1 protease in complex with the p1-p6 substrate variant (s451n) |
|
18
|
99
|
4mc6A |
Hiv protease in complex with sa499 |
|
18
|
99
|
4mc9A |
Hiv protease in complex with aa74 |
|
18
|
100
|
4m8yA |
Gs-8374, a novel phosphonate-containing inhibitor of hiv-1 protease, effectively inhibits hiv pr mutants with amino acid insertions |
|
20
|
99
|
4mc1A |
Hiv protease in complex with sa526p |
|
19
|
99
|
4mc2A |
Hiv protease in complex with sa525p |
|
18
|
99
|
4ll3A |
Structure of wild-type hiv protease in complex with darunavir |
|
19
|
99
|
4m8xA |
Gs-8374, a novel phosphonate-containing inhibitor of hiv-1 protease, effectively inhibits hiv pr mutants with amino acid insertions |
|
17
|
99
|
4l1aB |
Crystallographic study of multi-drug resistant hiv-1 protease lopinavir complex: mechanism of drug recognition and resistance |
|
16
|
99
|
4l1aA |
Crystallographic study of multi-drug resistant hiv-1 protease lopinavir complex: mechanism of drug recognition and resistance |
|
18
|
99
|
4kb9A |
Crystal structure of wild-type hiv-1 protease with novel tricyclic p2-ligands grl-0739a |
|
17
|
99
|
4k4qA |
Tl-3 inhibited trp6ala hiv protease with 3-bromo-2,6-dimethoxybenzoic acid bound in flap site |
|
18
|
99
|
4k4pA |
Tl-3 inhibited trp6ala hiv protease |
|
19
|
99
|
4k4rA |
Tl-3 inhibited trp6ala hiv protease with 1-bromo-2-napthoic acid bound in exosite |
|
18
|
99
|
4i8wA |
Crystal structure of wild type hiv-1 protease in complex with non-peptidic inhibitor, grl007 |
|
20
|
99
|
4i8zA |
Crystal structure of wild type hiv-1 protease in complex with non-peptidic inhibitor, grl008 |
|
17
|
99
|
4j54A |
Crystal structure of multidrug resistant hiv-1 protease clinical isolate pr20 with the potent antiviral inhibitor grl-0519a |
|
15
|
99
|
4j55A |
Crystal structure of multidrug resistant hiv-1 protease clinical isolate pr20 with the potent antiviral inhibitor grl-02031 |
|
16
|
99
|
4j5jA |
Crystal structure of multidrug resistant hiv-1 protease clinical isolate pr20 in complex with amprenavir |
|
19
|
99
|
4jecA |
Joint neutron and x-ray structure of per-deuterated hiv-1 protease in complex with clinical inhibitor amprenavir |
|
15
|
99
|
4hvpA |
Structure of complex of synthetic hiv-1 protease with a substrate-based inhibitor at 2.3 angstroms resolution |
|
20
|
99
|
4hegA |
Crystal structure of hiv-1 protease mutants r8q complexed with inhibitor grl-0519 |
|
19
|
99
|
4hlaA |
Crystal structure of wild type hiv-1 protease in complex with darunavir |
|
20
|
99
|
4he9A |
Crystal structure of hiv-1 protease mutants i54m complexed with inhibitor grl-0519 |
|
19
|
99
|
4hdfA |
Crystal structure of hiv-1 protease mutants v82a complexed with inhibitor grl-0519 |
|
19
|
99
|
4hdpA |
Crystal structure of hiv-1 protease mutants i50v complexed with inhibitor grl-0519 |
|
18
|
99
|
4hdbA |
Crystal structure of hiv-1 protease mutants d30n complexed with inhibitor grl-0519 |
|
15
|
99
|
4gyeA |
Mdr 769 hiv-1 protease in complex with reduced p1f |
|
17
|
99
|
4gzfA |
Multi-drug resistant hiv-1 protease 769 variant with reduced lrf peptide |
|
16
|
99
|
4gb2A |
Hiv-1 protease (mutant q7k l33i l63i) in complex with a bicyclic pyrrolidine inhibitor |
|
18
|
99
|
4flgA |
Hiv-1 protease mutant i47v complexed with reaction intermediate |
|
16
|
99
|
3r0wA |
Crystal structures of multidrug-resistant hiv-1 protease in complex with mechanism-based aspartyl protease inhibitors. |