1LML | Genus

Total Genus 135

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	135
sequence length	475
structure length	465
Chain Sequence	VVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGVSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKASYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Leishmanolysin
publication title	The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63). pubmed doi rcsb
molecule keywords	LEISHMANOLYSIN
total genus	135
structure length	465
sequence length	475
ec nomenclature	ec 3.4.24.36: Leishmanolysin.
pdb deposition date	1997-03-13

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.55.10	Mainly Beta	Ribbon	Leishmanolysin; domain 3	Leishmanolysin domain 3	1lmlA03
2.30.34.10	Mainly Beta	Roll	Leishmanolysin; domain 4	Leishmanolysin domain 4	1lmlA04
3.10.170.20	Alpha Beta	Roll	Elastase; domain 1	Elastase; domain 1	1lmlA01
3.90.132.10	Alpha Beta	Alpha-Beta Complex	Leishmanolysin; domain 2	Leishmanolysin , domain 2	1lmlA02

1LMLA
chains in the Genus database with same CATH superfamily

1LNBE 3QGOA 3NQXA 1LNFE 3TMNE 1ZDPE 1FJQA 7TLIA 3FXPA 2VQXA 1Z9GE 5JT9E 1QF0A 1LNCE 3P7QE 4GERA 3T74A 5TMNE 2A7GE 8TLNE 3FVPA 1KL6A 4TLNA 5FXNA 3P7UE 1LNAE 5JVIE 3FORA 1NPCA 1KTOA 1U4GA 3SSBA 5FSSA 1LNEE 1Y3GE 1KKKA 2TMNE 3P7VE 5A3YA 1LNDE 2WI0A 2WHZA 3DBKA 4B52A 1TMNE 3T2IE 3P7SE 3QH5A 4TNLA 1KEIA 4MZNE 1KS7A 1ESPA 1EZMA 5L8PE 4D91A 1KJPA 4TMNE 4M65A 5L3UE 1FJOA 1GXWA 3FV4A 4D9WA 4MTWE 4N4EE 2TLXA 1BQBA 3MS3A 3P7TE 5JSSE 1FJUA 1KJOA 3T8FA 5LIFE 3NN7A 3P7PE 8TLIA 4K90A 1PE5A 1FJWA 1QF2A 3F2PA 1FJ3A 3MSAA 5JS3E 3LS7A 3ZI6A 4TLIA 4N66E 4N5PE 5FSJA 3MSNA 3DO2A 1L3FE 7TLNA 3T87A 1KR6A 4OI5E 3NQZB 3DNZA 3QH1A 2TLIA 4H57A 3EIMA 1TLPE 5DPFE 2G4ZA 5DLHA 3T8DA 1TLIA 1LMLA 1FJTA 3T73A 4MWPE 1OS0A 5DPEE 5L41E 5TLNA 3NQYB 4OW3A 3FCQA 3FBOA 6TLIA 3FLFA 3P7WE 1HYTA 3DO1A 1QF1A 5K7TA 5JXNE 3T2JE 3T8GA 3DO0A 5TLIA 3FXSA 3MSFA 3FB0A 4MXJE 3F28A 1KROA 1TLXA 3TLIA 1PE8A 3N21A 3T8HA 5HQDA 5LWDE 1PE7A 3T2HE 6TMNE 3T8CA 4K89A 5FSPA 1THLA 3FGDA 1FJVA 3P7RE
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1LML A; 
#chains in the Genus database with same CATH topology
 1LNB E;  3QGO A;  3NQX A;  1LNF E;  3TMN E;  1ZDP E;  1FJQ A;  7TLI A;  3FXP A;  2VQX A;  1Z9G E;  5JT9 E;  1QF0 A;  1LNC E;  3P7Q E;  4GER A;  3T74 A;  5TMN E;  2A7G E;  8TLN E;  3FVP A;  1KL6 A;  4TLN A;  5FXN A;  3P7U E;  1LNA E;  5JVI E;  3FOR A;  1NPC A;  1KTO A;  1U4G A;  3SSB A;  5FSS A;  1LNE E;  1Y3G E;  1KKK A;  2TMN E;  3P7V E;  5A3Y A;  1LND E;  2WI0 A;  2WHZ A;  3DBK A;  4B52 A;  1TMN E;  3T2I E;  3P7S E;  3QH5 A;  4TNL A;  1KEI A;  4MZN E;  1KS7 A;  1ESP A;  1EZM A;  5L8P E;  4D91 A;  1KJP A;  4TMN E;  4M65 A;  5L3U E;  1FJO A;  1GXW A;  3FV4 A;  4D9W A;  4MTW E;  4N4E E;  2TLX A;  1BQB A;  3MS3 A;  3P7T E;  5JSS E;  1FJU A;  1KJO A;  3T8F A;  5LIF E;  3NN7 A;  3P7P E;  8TLI A;  4K90 A;  1PE5 A;  1FJW A;  1QF2 A;  3F2P A;  1FJ3 A;  3MSA A;  5JS3 E;  3LS7 A;  3ZI6 A;  4TLI A;  4N66 E;  4N5P E;  5FSJ A;  3MSN A;  3DO2 A;  1L3F E;  7TLN A;  3T87 A;  1KR6 A;  4OI5 E;  3NQZ B;  3DNZ A;  3QH1 A;  2TLI A;  4H57 A;  3EIM A;  1TLP E;  5DPF E;  2G4Z A;  5DLH A;  3T8D A;  1TLI A;  1LML A;  1FJT A;  3T73 A;  4MWP E;  1OS0 A;  5DPE E;  5L41 E;  5TLN A;  3NQY B;  4OW3 A;  3FCQ A;  3FBO A;  6TLI A;  3FLF A;  3P7W E;  1HYT A;  3DO1 A;  1QF1 A;  5K7T A;  5JXN E;  3T2J E;  3T8G A;  3DO0 A;  5TLI A;  3FXS A;  3MSF A;  3FB0 A;  4MXJ E;  3F28 A;  1KRO A;  1TLX A;  3TLI A;  1PE8 A;  3N21 A;  3T8H A;  5HQD A;  5LWD E;  1PE7 A;  3T2H E;  6TMN E;  3T8C A;  4K89 A;  5FSP A;  1THL A;  3FGD A;  1FJV A;  3P7R E; 
#chains in the Genus database with same CATH homology
 1LNB E;  3QGO A;  3NQX A;  1LNF E;  3TMN E;  1ZDP E;  1FJQ A;  7TLI A;  3FXP A;  2VQX A;  1Z9G E;  5JT9 E;  1QF0 A;  1LNC E;  3P7Q E;  4GER A;  3T74 A;  5TMN E;  2A7G E;  8TLN E;  3FVP A;  1KL6 A;  4TLN A;  5FXN A;  3P7U E;  1LNA E;  5JVI E;  3FOR A;  1NPC A;  1KTO A;  1U4G A;  3SSB A;  5FSS A;  1LNE E;  1Y3G E;  1KKK A;  2TMN E;  3P7V E;  5A3Y A;  1LND E;  2WI0 A;  2WHZ A;  3DBK A;  4B52 A;  1TMN E;  3T2I E;  3P7S E;  3QH5 A;  4TNL A;  1KEI A;  4MZN E;  1KS7 A;  1ESP A;  1EZM A;  5L8P E;  4D91 A;  1KJP A;  4TMN E;  4M65 A;  5L3U E;  1FJO A;  1GXW A;  3FV4 A;  4D9W A;  4MTW E;  4N4E E;  2TLX A;  1BQB A;  3MS3 A;  3P7T E;  5JSS E;  1FJU A;  1KJO A;  3T8F A;  5LIF E;  3NN7 A;  3P7P E;  8TLI A;  4K90 A;  1PE5 A;  1FJW A;  1QF2 A;  3F2P A;  1FJ3 A;  3MSA A;  5JS3 E;  3LS7 A;  3ZI6 A;  4TLI A;  4N66 E;  4N5P E;  5FSJ A;  3MSN A;  3DO2 A;  1L3F E;  7TLN A;  3T87 A;  1KR6 A;  4OI5 E;  3NQZ B;  3DNZ A;  3QH1 A;  2TLI A;  4H57 A;  3EIM A;  1TLP E;  5DPF E;  2G4Z A;  5DLH A;  3T8D A;  1TLI A;  1LML A;  1FJT A;  3T73 A;  4MWP E;  1OS0 A;  5DPE E;  5L41 E;  5TLN A;  3NQY B;  4OW3 A;  3FCQ A;  3FBO A;  6TLI A;  3FLF A;  3P7W E;  1HYT A;  3DO1 A;  1QF1 A;  5K7T A;  5JXN E;  3T2J E;  3T8G A;  3DO0 A;  5TLI A;  3FXS A;  3MSF A;  3FB0 A;  4MXJ E;  3F28 A;  1KRO A;  1TLX A;  3TLI A;  1PE8 A;  3N21 A;  3T8H A;  5HQD A;  5LWD E;  1PE7 A;  3T2H E;  6TMN E;  3T8C A;  4K89 A;  5FSP A;  1THL A;  3FGD A;  1FJV A;  3P7R E;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1LMLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization