1LMLA

Leishmanolysin
Total Genus 135
50100150200250300350400450020406080100120140
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
475
structure length
465
Chain Sequence
VVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGVSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKASYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKD
50100150200250300350400450400300200100
020406080100120Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Leishmanolysin
publication title The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63).
pubmed doi rcsb
molecule keywords LEISHMANOLYSIN
total genus 135
structure length 465
sequence length 475
ec nomenclature ec 3.4.24.36: Leishmanolysin.
pdb deposition date 1997-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.55.10 Mainly Beta Ribbon Leishmanolysin; domain 3 Leishmanolysin domain 3 1lmlA03
2.30.34.10 Mainly Beta Roll Leishmanolysin; domain 4 Leishmanolysin domain 4 1lmlA04
3.10.170.20 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 1lmlA01
3.90.132.10 Alpha Beta Alpha-Beta Complex Leishmanolysin; domain 2 Leishmanolysin , domain 2 1lmlA02
1LMLA
chains in the Genus database with same CATH superfamily
3N21A 1KJOA 1EZMA 3T2JE 1FJ3A 5JVIE 4N4EE 3DO2A 3P7TE 4OW3A 5FSPA 3NN7A 1ZDPE 1KROA 4MZNE 2VQXA 5L8PE 3TLIA 1FJQA 1LNAE 4MWPE 3SSBA 1KEIA 1PE8A 1QF2A 3T73A 1U4GA 1LNFE 5DPEE 1PE7A 2A7GE 3T87A 5DLHA 3F2PA 3T8FA 2WI0A 4MXJE 5A3YA 1TLIA 1TLXA 3FV4A 3MS3A 3QH1A 1QF1A 5K7TA 5FSJA 3T8DA 5JS3E 4N66E 4K89A 5DPFE 3MSNA 1KKKA 4TLNA 3FB0A 1LNBE 2G4ZA 4GERA 2TLXA 5TMNE 3FXPA 3P7PE 5L41E 1QF0A 3FLFA 1THLA 3QH5A 3T2IE 1KL6A 1KR6A 2TMNE 1KJPA 1LNCE 5HQDA 3FCQA 1FJOA 1BQBA 3T8CA 1LNDE 3P7RE 4N5PE 1OS0A 3T8HA 3NQXA 7TLIA 1LMLA 1Z9GE 1GXWA 1HYTA 3DBKA 3FORA 3P7VE 3F28A 3T74A 3EIMA 3T8GA 3P7UE 3P7SE 5L3UE 4D91A 4TMNE 1FJUA 4MTWE 1LNEE 5TLNA 3DNZA 3NQYB 4H57A 3T2HE 1PE5A 3FBOA 3NQZB 3FVPA 8TLNE 5JXNE 4TLIA 3QGOA 1TMNE 8TLIA 2WHZA 3ZI6A 5FXNA 4D9WA 3FGDA 3LS7A 4TNLA 5LWDE 5JT9E 3DO0A 1FJVA 3TMNE 5FSSA 1FJWA 3FXSA 6TMNE 5JSSE 3P7QE 3MSAA 5TLIA 1TLPE 3P7WE 4B52A 2TLIA 5LIFE 1L3FE 6TLIA 1KTOA 1NPCA 1Y3GE 4K90A 7TLNA 4M65A 4OI5E 1FJTA 1KS7A 1ESPA 3DO1A 3MSFA
chains in the Genus database with same CATH topology
3N21A 1KJOA 1EZMA 3T2JE 1FJ3A 5JVIE 4N4EE 3DO2A 3P7TE 4OW3A 5FSPA 3NN7A 1ZDPE 1KROA 4MZNE 2VQXA 5L8PE 3TLIA 1FJQA 1LNAE 4MWPE 3SSBA 1KEIA 1PE8A 1QF2A 3T73A 1U4GA 1LNFE 5DPEE 1PE7A 2A7GE 3T87A 5DLHA 3F2PA 3T8FA 2WI0A 4MXJE 5A3YA 1TLIA 1TLXA 3FV4A 3MS3A 3QH1A 1QF1A 5K7TA 5FSJA 3T8DA 5JS3E 4N66E 4K89A 5DPFE 3MSNA 1KKKA 4TLNA 3FB0A 1LNBE 2G4ZA 4GERA 2TLXA 5TMNE 3FXPA 3P7PE 5L41E 1QF0A 3FLFA 1THLA 3QH5A 3T2IE 1KL6A 1KR6A 2TMNE 1KJPA 1LNCE 5HQDA 3FCQA 1FJOA 1BQBA 3T8CA 1LNDE 3P7RE 4N5PE 1OS0A 3T8HA 3NQXA 7TLIA 1LMLA 1Z9GE 1GXWA 1HYTA 3DBKA 3FORA 3P7VE 3F28A 3T74A 3EIMA 3T8GA 3P7UE 3P7SE 5L3UE 4D91A 4TMNE 1FJUA 4MTWE 1LNEE 5TLNA 3DNZA 3NQYB 4H57A 3T2HE 1PE5A 3FBOA 3NQZB 3FVPA 8TLNE 5JXNE 4TLIA 3QGOA 1TMNE 8TLIA 2WHZA 3ZI6A 5FXNA 4D9WA 3FGDA 3LS7A 4TNLA 5LWDE 5JT9E 3DO0A 1FJVA 3TMNE 5FSSA 1FJWA 3FXSA 6TMNE 5JSSE 3P7QE 3MSAA 5TLIA 1TLPE 3P7WE 4B52A 2TLIA 5LIFE 1L3FE 6TLIA 1KTOA 1NPCA 1Y3GE 4K90A 7TLNA 4M65A 4OI5E 1FJTA 1KS7A 1ESPA 3DO1A 3MSFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LML A; 
#chains in the Genus database with same CATH topology
 3N21 A;  1KJO A;  1EZM A;  3T2J E;  1FJ3 A;  5JVI E;  4N4E E;  3DO2 A;  3P7T E;  4OW3 A;  5FSP A;  3NN7 A;  1ZDP E;  1KRO A;  4MZN E;  2VQX A;  5L8P E;  3TLI A;  1FJQ A;  1LNA E;  4MWP E;  3SSB A;  1KEI A;  1PE8 A;  1QF2 A;  3T73 A;  1U4G A;  1LNF E;  5DPE E;  1PE7 A;  2A7G E;  3T87 A;  5DLH A;  3F2P A;  3T8F A;  2WI0 A;  4MXJ E;  5A3Y A;  1TLI A;  1TLX A;  3FV4 A;  3MS3 A;  3QH1 A;  1QF1 A;  5K7T A;  5FSJ A;  3T8D A;  5JS3 E;  4N66 E;  4K89 A;  5DPF E;  3MSN A;  1KKK A;  4TLN A;  3FB0 A;  1LNB E;  2G4Z A;  4GER A;  2TLX A;  5TMN E;  3FXP A;  3P7P E;  5L41 E;  1QF0 A;  3FLF A;  1THL A;  3QH5 A;  3T2I E;  1KL6 A;  1KR6 A;  2TMN E;  1KJP A;  1LNC E;  5HQD A;  3FCQ A;  1FJO A;  1BQB A;  3T8C A;  1LND E;  3P7R E;  4N5P E;  1OS0 A;  3T8H A;  3NQX A;  7TLI A;  1LML A;  1Z9G E;  1GXW A;  1HYT A;  3DBK A;  3FOR A;  3P7V E;  3F28 A;  3T74 A;  3EIM A;  3T8G A;  3P7U E;  3P7S E;  5L3U E;  4D91 A;  4TMN E;  1FJU A;  4MTW E;  1LNE E;  5TLN A;  3DNZ A;  3NQY B;  4H57 A;  3T2H E;  1PE5 A;  3FBO A;  3NQZ B;  3FVP A;  8TLN E;  5JXN E;  4TLI A;  3QGO A;  1TMN E;  8TLI A;  2WHZ A;  3ZI6 A;  5FXN A;  4D9W A;  3FGD A;  3LS7 A;  4TNL A;  5LWD E;  5JT9 E;  3DO0 A;  1FJV A;  3TMN E;  5FSS A;  1FJW A;  3FXS A;  6TMN E;  5JSS E;  3P7Q E;  3MSA A;  5TLI A;  1TLP E;  3P7W E;  4B52 A;  2TLI A;  5LIF E;  1L3F E;  6TLI A;  1KTO A;  1NPC A;  1Y3G E;  4K90 A;  7TLN A;  4M65 A;  4OI5 E;  1FJT A;  1KS7 A;  1ESP A;  3DO1 A;  3MSF A; 
#chains in the Genus database with same CATH homology
 3N21 A;  1KJO A;  1EZM A;  3T2J E;  1FJ3 A;  5JVI E;  4N4E E;  3DO2 A;  3P7T E;  4OW3 A;  5FSP A;  3NN7 A;  1ZDP E;  1KRO A;  4MZN E;  2VQX A;  5L8P E;  3TLI A;  1FJQ A;  1LNA E;  4MWP E;  3SSB A;  1KEI A;  1PE8 A;  1QF2 A;  3T73 A;  1U4G A;  1LNF E;  5DPE E;  1PE7 A;  2A7G E;  3T87 A;  5DLH A;  3F2P A;  3T8F A;  2WI0 A;  4MXJ E;  5A3Y A;  1TLI A;  1TLX A;  3FV4 A;  3MS3 A;  3QH1 A;  1QF1 A;  5K7T A;  5FSJ A;  3T8D A;  5JS3 E;  4N66 E;  4K89 A;  5DPF E;  3MSN A;  1KKK A;  4TLN A;  3FB0 A;  1LNB E;  2G4Z A;  4GER A;  2TLX A;  5TMN E;  3FXP A;  3P7P E;  5L41 E;  1QF0 A;  3FLF A;  1THL A;  3QH5 A;  3T2I E;  1KL6 A;  1KR6 A;  2TMN E;  1KJP A;  1LNC E;  5HQD A;  3FCQ A;  1FJO A;  1BQB A;  3T8C A;  1LND E;  3P7R E;  4N5P E;  1OS0 A;  3T8H A;  3NQX A;  7TLI A;  1LML A;  1Z9G E;  1GXW A;  1HYT A;  3DBK A;  3FOR A;  3P7V E;  3F28 A;  3T74 A;  3EIM A;  3T8G A;  3P7U E;  3P7S E;  5L3U E;  4D91 A;  4TMN E;  1FJU A;  4MTW E;  1LNE E;  5TLN A;  3DNZ A;  3NQY B;  4H57 A;  3T2H E;  1PE5 A;  3FBO A;  3NQZ B;  3FVP A;  8TLN E;  5JXN E;  4TLI A;  3QGO A;  1TMN E;  8TLI A;  2WHZ A;  3ZI6 A;  5FXN A;  4D9W A;  3FGD A;  3LS7 A;  4TNL A;  5LWD E;  5JT9 E;  3DO0 A;  1FJV A;  3TMN E;  5FSS A;  1FJW A;  3FXS A;  6TMN E;  5JSS E;  3P7Q E;  3MSA A;  5TLI A;  1TLP E;  3P7W E;  4B52 A;  2TLI A;  5LIF E;  1L3F E;  6TLI A;  1KTO A;  1NPC A;  1Y3G E;  4K90 A;  7TLN A;  4M65 A;  4OI5 E;  1FJT A;  1KS7 A;  1ESP A;  3DO1 A;  3MSF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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