4TMNE

Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGDGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSEMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords THERMOLYSIN
publication title Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
pubmed doi rcsb
source organism Bacillus thermoproteolyticus
total genus 117
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 1987-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
E PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 4tmnE02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 4tmnE01
4J3BA 4XN7A 1ZDPE 3P7RE 4OW3A 4TLIA 3EBGA 2XPYA 1QF1A 3CHQA 3FTXA 3B7RL 3FUDA 1TLPE 3P7SE 2TMNE 1QF2A 1Z9GE 5LWDE 2HPOA 3FBOA 3FTZA 1OS0A 3B34A 3FB0A 4MTWE 3FU0A 1QF0A 3CHOA 3FUHA 1KL6A 5A3YA 4K89A 4QHPA 4XO4A 4MS6A 3FUJA 4GERA 4ZW6A 4Q4IA 3CHPA 4K5OA 5FWQA 3CIAA 4TLNA 1KJOA 3DO0A 1U4GA 4N4EE 3FHEA 1TMNE 4D91A 1NPCA 1KROA 1TRLA 3FULA 4ZW3A 4MWPE 4N5PE 7TLNA 2ZXGA 3T8CA 1EZMA 4K5PA 5FSPA 1LNEE 4ZX6A 3TLIA 3DO2A 1FJOA 1KJPA 3MSAA 4H57A 3LS7A 4XMTA 4ZW7A 2TLXA 2DQMA 1LNFE 1BQBA 1KR6A 4MXJE 4K90A 4R7LA 4QPEA 4RVBA 3ZI6A 6TMNE 3P7WE 3QGOA 5HQDA 5DYFA 4ZQTA 4L2LA 4DPRA 1FJUA 2R59A 3B3BA 3CHRA 4XN4A 3NQYB 4XN9A 3B2XA 3T8FA 2TLIA 2WI0A 4ZX5A 3NQXA 5JT9E 2XPZA 3FUFA 3U9WA 3F2PA 5DPFE 3QH1A 3FU5A 4B52A 1FJVA 3DNZA 1GW6A 5L8PE 2GTQA 3T73A 3T8VA 4XNDA 3B37A 3FU3A 1HS6A 1KKKA 1HYTA 4MZNE 4OI5E 5LIFE 3T8HA 3KEDA 3PUUA 3P7QE 1FJWA 3MS3A 3FCQA 3FVPA 3FLFA 4XNAA 4XN5A 5DPEE 4X2UA 3B7UX 3FUNA 4Q4EA 8TLIA 1KTOA 1FJ3A 4PW4A 4XMUA 1TLXA 3FV4A 3FGDA 2G4ZA 5DLHA 3T87A 5L41E 4ZX4A 3FU6A 2VJ8A 3FTYA 3F28A 2DQ6A 3CHSA 3EBIA 5FSJA 1LNCE 4GAAA 4QMEA 4RSYA 3FTUA 3FUMA 3T2IE 1SQMA 1PE5A 3DBKA 4ZW5A 5TLNA 3SSBA 2HPTA 3FUEA 4QIRA 3QJXA 4ZW8A 3NQZB 3N21A 4R5TA 3DO1A 3MSFA 3FXPA 5FXNA 3T8DA 4XO5A 1GXWA 3TMNE 5TMNE 4XN8A 3NN7A 1Y3GE 3Q43A 3B7TA 3T74A 3FTSA 2A7GE 4R5VA 4QUOA 1L3FE 5BPPA 1THLA 3EBHA 5L3UE 3FUIA 5DLLA 4K5MA 4XMZA 1LNAE 1PE8A 4K5NA 4ZX3A 1KEIA 3FH5A 1KS7A 5JS3E 4TNLA 3B7SA 4R5XA 3P7UE 4XO3A 4M65A 1PE7A 4D9WA 4XNBA 3P7TE 6TLIA 3FUKA 3FH8A 4MKTA 4N66E 1H19A 5JXNE 4XN1A 3EIMA 3Q44A 3T8GA 4K5LA 4PVBA 5TLIA 3FTWA 3T2HE 7TLIA 3QH5A 1TLIA 4XMVA 3FTVA 5FSSA 1FJTA 2XQ0A 4PU2A 4XN2A 2VQXA 5AENA 5JSSE 1LNBE 5K7TA 1FJQA 2WHZA 3FORA 3T2JE 3FXSA 4XMXA 5JVIE 4XMWA 4TMNE 3MSNA 8TLNE 3B2PA 3P7VE 1LNDE 3P7PE 1ESPA 3FH7A
chains in the Genus database with same CATH superfamily
3ZI6A 4OW3A 4TLIA 3EBGA 1QF1A 5C97A 5LWDE 3FTZA 3B34A 4KXAA 1QF0A 5AB2A 4K89A 3FUJA 3CHPA 3CIAA 3DO0A 1U4GA 4N4EE 1TMNE 3FULA 7TLNA 3T8CA 1LNEE 4ZX6A 3TLIA 3MSAA 1LNFE 1BQBA 4K90A 3QGOA 5DYFA 4L2LA 4ARFA 3B3BA 3CHRA 4XN4A 4XN9A 4ZX5A 3U9WA 4OU3A 4B52A 1FJVA 3T8VA 3T73A 4XNDA 1KKKA 3T8HA 3KEDA 3PUUA 4XN5A 4Q4EA 3FGDA 4NZ8A 2G4ZA 5FSJA 4QMEA 3FTUA 3FUMA 1PE5A 4ZW5A 3SSBA 4ZW8A 3N21A 3DO1A 3FXPA 3TMNE 5TMNE 4XN8A 1Y3GE 3Q43A 4QUOA 3EBHA 5JS3E 3B7SA 1Z1WA 4XO3A 4M65A 1PE7A 4XNBA 3FUKA 4MKTA 4N66E 1H19A 3EIMA 4KX9A 3T2HE 1TLIA 1FJQA 3T2JE 3FXSA 3P7VE 5A3YA 4J3BA 4XN7A 1ZDPE 3P7RE 3CHQA 3P7SE 3B7RL 2TMNE 4E36A 2HPOA 4IHQA 4MTWE 3FU0A 1KL6A 4MS6A 4Q4IA 4K5OA 5FWQA 4TLNA 1KJOA 4HOMA 3FHEA 4ZW3A 2ZXGA 1EZMA 4K5PA 5FSPA 1KJPA 2TLXA 4QPEA 4R7LA 1Z5HA 5HQDA 4DPRA 2R59A 3B2XA 3F2PA 5DPFE 3QH1A 3DNZA 1GW6A 2GTQA 4FYRA 1FJWA 3MS3A 3FVPA 4KXBA 4XNAA 5LHDA 4FKEA 1KTOA 1FJ3A 5DLHA 3T87A 3FU6A 3SE6A 3F28A 3CHSA 5LG6A 4GAAA 4KXCA 3FUEA 4QIRA 3NQZB 4FCAA 3MSFA 5FXNA 4JBSA 3NN7A 4R5VA 2A7GE 5BPPA 1PE8A 4R5XA 3QNFA 3FH8A 3MDJA 5JXNE 4XN1A 4K5LA 7TLIA 5JSSE 4XN2A 4Z7IA 5JVIE 4XMWA 1ESPA 3FH7A 4ZX4A 1TLPE 1Z9GE 4KX8A 3FBOA 1OS0A 3FB0A 4XO4A 1NPCA 4FYQA 4MWPE 4N5PE 5CU5A 4AR9A 3DO2A 1FJOA 3LS7A 2DQMA 3NQYB 3T8FA 3NQXA 5JT9E 4FYTA 3FUFA 3FU5A 4AR1A 5L8PE 1LMLA 3B37A 1HS6A 5LIFE 4OI5E 4FGMA 3FCQA 3FLFA 4X2UA 3FUNA 8TLIA 4AR8A 1TLXA 3FV4A 5L41E 2VJ8A 2DQ6A 3EBIA 1LNCE 3DBKA 5TLNA 4WZ9A 4R5TA 5EV7A 3T8DA 4XO5A 1GXWA 3T74A 3B7TA 3FTSA 1L3FE 3FUIA 4FYSA 5DLLA 4XMZA 1LNAE 4K5NA 4ZX3A 3FH5A 4D9WA 4FKHA 4PVBA 3T8GA 5J6SA 3FTWA 5FSSA 3FTVA 2XQ0A 1LNBE 5K7TA 2WHZA 3FORA 4XMXA 4TMNE 3MSNA 4P8QA 3T2IE 2XPYA 3FTXA 3FUDA 1QF2A 2YD0A 4NAQA 3CHOA 3FUHA 5K1VA 4QHPA 4ZW6A 4GERA 4D91A 1KROA 1TRLA 4KX7A 4H57A 4XMTA 4ZW7A 6TMNE 4MXJE 1KR6A 4RVBA 3P7WE 4ZQTA 1FJUA 4PJ6A 2TLIA 3Q7JA 2WI0A 2XPZA 4F5CA 3FU3A 1HYTA 4MZNE 3P7QE 5DPEE 3B7UX 4XMUA 4PW4A 4KXDA 5LDSA 3FTYA 4FKKA 4RSYA 1SQMA 2HPTA 3QJXA 1THLA 5L3UE 4K5MA 5AB0A 1KEIA 1KS7A 4TNLA 3P7UE 3P7TE 6TLIA 4II7A 3Q44A 5TLIA 3QH5A 4XMVA 1FJTA 4PU2A 5AENA 2VQXA 8TLNE 3B2PA 1LNDE 3P7PE
chains in the Genus database with same CATH topology
4J3BA 4XN7A 1ZDPE 3P7RE 4OW3A 4TLIA 3EBGA 2XPYA 1QF1A 3CHQA 3FTXA 3B7RL 3FUDA 1TLPE 3P7SE 2TMNE 1QF2A 1Z9GE 5LWDE 2HPOA 3FBOA 3FTZA 1OS0A 3B34A 3FB0A 4MTWE 3FU0A 1QF0A 3CHOA 3FUHA 1KL6A 5A3YA 4K89A 4QHPA 4XO4A 4MS6A 3FUJA 4GERA 4ZW6A 4Q4IA 3CHPA 4K5OA 5FWQA 3CIAA 4TLNA 1KJOA 3DO0A 1U4GA 4N4EE 3FHEA 1TMNE 4D91A 1NPCA 1KROA 1TRLA 3FULA 4ZW3A 4MWPE 4N5PE 7TLNA 2ZXGA 3T8CA 1EZMA 4K5PA 5FSPA 1LNEE 4ZX6A 3TLIA 3DO2A 1FJOA 1KJPA 3MSAA 4H57A 3LS7A 4XMTA 4ZW7A 2TLXA 2DQMA 1LNFE 1BQBA 1KR6A 4MXJE 4K90A 4R7LA 4QPEA 4RVBA 3ZI6A 6TMNE 3P7WE 3QGOA 5HQDA 5DYFA 4ZQTA 4L2LA 4DPRA 1FJUA 2R59A 3B3BA 3CHRA 4XN4A 3NQYB 4XN9A 3B2XA 3T8FA 2TLIA 2WI0A 4ZX5A 3NQXA 5JT9E 2XPZA 3FUFA 3U9WA 3F2PA 5DPFE 3QH1A 3FU5A 4B52A 1FJVA 3DNZA 1GW6A 5L8PE 1LMLA 2GTQA 3T73A 3T8VA 4XNDA 3B37A 3FU3A 1HS6A 1KKKA 1HYTA 4MZNE 4OI5E 5LIFE 3T8HA 3KEDA 3PUUA 3P7QE 1FJWA 3MS3A 3FCQA 3FVPA 3FLFA 4XNAA 4XN5A 5DPEE 4X2UA 3B7UX 3FUNA 4Q4EA 8TLIA 1KTOA 1FJ3A 4PW4A 4XMUA 1TLXA 3FV4A 3FGDA 2G4ZA 5DLHA 3T87A 5L41E 4ZX4A 3FU6A 2VJ8A 3FTYA 3F28A 2DQ6A 3CHSA 3EBIA 5FSJA 1LNCE 4GAAA 4QMEA 4RSYA 3FTUA 3FUMA 3T2IE 1SQMA 1PE5A 3DBKA 4ZW5A 5TLNA 3SSBA 2HPTA 3FUEA 4QIRA 3QJXA 4ZW8A 3NQZB 3N21A 4R5TA 3DO1A 3MSFA 3FXPA 5FXNA 3T8DA 4XO5A 1GXWA 3TMNE 5TMNE 4XN8A 3NN7A 1Y3GE 3Q43A 3B7TA 3T74A 3FTSA 2A7GE 4R5VA 4QUOA 1L3FE 5BPPA 1THLA 3EBHA 5L3UE 3FUIA 5DLLA 4K5MA 4XMZA 1LNAE 1PE8A 4K5NA 4ZX3A 1KEIA 3FH5A 1KS7A 5JS3E 4TNLA 3B7SA 4R5XA 3P7UE 4XO3A 4M65A 1PE7A 4D9WA 4XNBA 3P7TE 6TLIA 3FUKA 3FH8A 4MKTA 4N66E 1H19A 5JXNE 4XN1A 3EIMA 3Q44A 3T8GA 4K5LA 4PVBA 5TLIA 3FTWA 3T2HE 7TLIA 3QH5A 1TLIA 4XMVA 3FTVA 5FSSA 1FJTA 2XQ0A 4PU2A 4XN2A 2VQXA 5AENA 5JSSE 1LNBE 5K7TA 1FJQA 2WHZA 3FORA 3T2JE 3FXSA 4XMXA 5JVIE 4XMWA 4TMNE 3MSNA 8TLNE 3B2PA 3P7VE 1LNDE 3P7PE 1ESPA 3FH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J3B A;  4XN7 A;  1ZDP E;  3P7R E;  4OW3 A;  4TLI A;  3EBG A;  2XPY A;  1QF1 A;  3CHQ A;  3FTX A;  3B7R L;  3FUD A;  1TLP E;  3P7S E;  2TMN E;  1QF2 A;  1Z9G E;  5LWD E;  2HPO A;  3FBO A;  3FTZ A;  1OS0 A;  3B34 A;  3FB0 A;  4MTW E;  3FU0 A;  1QF0 A;  3CHO A;  3FUH A;  1KL6 A;  5A3Y A;  4K89 A;  4QHP A;  4XO4 A;  4MS6 A;  3FUJ A;  4GER A;  4ZW6 A;  4Q4I A;  3CHP A;  4K5O A;  5FWQ A;  3CIA A;  4TLN A;  1KJO A;  3DO0 A;  1U4G A;  4N4E E;  3FHE A;  1TMN E;  4D91 A;  1NPC A;  1KRO A;  1TRL A;  3FUL A;  4ZW3 A;  4MWP E;  4N5P E;  7TLN A;  2ZXG A;  3T8C A;  1EZM A;  4K5P A;  5FSP A;  1LNE E;  4ZX6 A;  3TLI A;  3DO2 A;  1FJO A;  1KJP A;  3MSA A;  4H57 A;  3LS7 A;  4XMT A;  4ZW7 A;  2TLX A;  2DQM A;  1LNF E;  1BQB A;  1KR6 A;  4MXJ E;  4K90 A;  4R7L A;  4QPE A;  4RVB A;  3ZI6 A;  6TMN E;  3P7W E;  3QGO A;  5HQD A;  5DYF A;  4ZQT A;  4L2L A;  4DPR A;  1FJU A;  2R59 A;  3B3B A;  3CHR A;  4XN4 A;  3NQY B;  4XN9 A;  3B2X A;  3T8F A;  2TLI A;  2WI0 A;  4ZX5 A;  3NQX A;  5JT9 E;  2XPZ A;  3FUF A;  3U9W A;  3F2P A;  5DPF E;  3QH1 A;  3FU5 A;  4B52 A;  1FJV A;  3DNZ A;  1GW6 A;  5L8P E;  2GTQ A;  3T73 A;  3T8V A;  4XND A;  3B37 A;  3FU3 A;  1HS6 A;  1KKK A;  1HYT A;  4MZN E;  4OI5 E;  5LIF E;  3T8H A;  3KED A;  3PUU A;  3P7Q E;  1FJW A;  3MS3 A;  3FCQ A;  3FVP A;  3FLF A;  4XNA A;  4XN5 A;  5DPE E;  4X2U A;  3B7U X;  3FUN A;  4Q4E A;  8TLI A;  1KTO A;  1FJ3 A;  4PW4 A;  4XMU A;  1TLX A;  3FV4 A;  3FGD A;  2G4Z A;  5DLH A;  3T87 A;  5L41 E;  4ZX4 A;  3FU6 A;  2VJ8 A;  3FTY A;  3F28 A;  2DQ6 A;  3CHS A;  3EBI A;  5FSJ A;  1LNC E;  4GAA A;  4QME A;  4RSY A;  3FTU A;  3FUM A;  3T2I E;  1SQM A;  1PE5 A;  3DBK A;  4ZW5 A;  5TLN A;  3SSB A;  2HPT A;  3FUE A;  4QIR A;  3QJX A;  4ZW8 A;  3NQZ B;  3N21 A;  4R5T A;  3DO1 A;  3MSF A;  3FXP A;  5FXN A;  3T8D A;  4XO5 A;  1GXW A;  3TMN E;  5TMN E;  4XN8 A;  3NN7 A;  1Y3G E;  3Q43 A;  3B7T A;  3T74 A;  3FTS A;  2A7G E;  4R5V A;  4QUO A;  1L3F E;  5BPP A;  1THL A;  3EBH A;  5L3U E;  3FUI A;  5DLL A;  4K5M A;  4XMZ A;  1LNA E;  1PE8 A;  4K5N A;  4ZX3 A;  1KEI A;  3FH5 A;  1KS7 A;  5JS3 E;  4TNL A;  3B7S A;  4R5X A;  3P7U E;  4XO3 A;  4M65 A;  1PE7 A;  4D9W A;  4XNB A;  3P7T E;  6TLI A;  3FUK A;  3FH8 A;  4MKT A;  4N66 E;  1H19 A;  5JXN E;  4XN1 A;  3EIM A;  3Q44 A;  3T8G A;  4K5L A;  4PVB A;  5TLI A;  3FTW A;  3T2H E;  7TLI A;  3QH5 A;  1TLI A;  4XMV A;  3FTV A;  5FSS A;  1FJT A;  2XQ0 A;  4PU2 A;  4XN2 A;  2VQX A;  5AEN A;  5JSS E;  1LNB E;  5K7T A;  1FJQ A;  2WHZ A;  3FOR A;  3T2J E;  3FXS A;  4XMX A;  5JVI E;  4XMW A;  4TMN E;  3MSN A;  8TLN E;  3B2P A;  3P7V E;  1LND E;  3P7P E;  1ESP A;  3FH7 A; 
#chains in the Genus database with same CATH topology
 3ZI6 A;  4OW3 A;  4TLI A;  3EBG A;  1QF1 A;  5C97 A;  5LWD E;  3FTZ A;  3B34 A;  4KXA A;  1QF0 A;  5AB2 A;  4K89 A;  3FUJ A;  3CHP A;  3CIA A;  3DO0 A;  1U4G A;  4N4E E;  1TMN E;  3FUL A;  7TLN A;  3T8C A;  1LNE E;  4ZX6 A;  3TLI A;  3MSA A;  1LNF E;  1BQB A;  4K90 A;  3QGO A;  5DYF A;  4L2L A;  4ARF A;  3B3B A;  3CHR A;  4XN4 A;  4XN9 A;  4ZX5 A;  3U9W A;  4OU3 A;  4B52 A;  1FJV A;  3T8V A;  3T73 A;  4XND A;  1KKK A;  3T8H A;  3KED A;  3PUU A;  4XN5 A;  4Q4E A;  3FGD A;  4NZ8 A;  2G4Z A;  5FSJ A;  4QME A;  3FTU A;  3FUM A;  1PE5 A;  4ZW5 A;  3SSB A;  4ZW8 A;  3N21 A;  3DO1 A;  3FXP A;  3TMN E;  5TMN E;  4XN8 A;  1Y3G E;  3Q43 A;  4QUO A;  3EBH A;  5JS3 E;  3B7S A;  1Z1W A;  4XO3 A;  4M65 A;  1PE7 A;  4XNB A;  3FUK A;  4MKT A;  4N66 E;  1H19 A;  3EIM A;  4KX9 A;  3T2H E;  1TLI A;  1FJQ A;  3T2J E;  3FXS A;  3P7V E;  5A3Y A;  4J3B A;  4XN7 A;  1ZDP E;  3P7R E;  3CHQ A;  3P7S E;  3B7R L;  2TMN E;  4E36 A;  2HPO A;  4IHQ A;  4MTW E;  3FU0 A;  1KL6 A;  4MS6 A;  4Q4I A;  4K5O A;  5FWQ A;  4TLN A;  1KJO A;  4HOM A;  3FHE A;  4ZW3 A;  2ZXG A;  1EZM A;  4K5P A;  5FSP A;  1KJP A;  2TLX A;  4QPE A;  4R7L A;  1Z5H A;  5HQD A;  4DPR A;  2R59 A;  3B2X A;  3F2P A;  5DPF E;  3QH1 A;  3DNZ A;  1GW6 A;  2GTQ A;  4FYR A;  1FJW A;  3MS3 A;  3FVP A;  4KXB A;  4XNA A;  5LHD A;  4FKE A;  1KTO A;  1FJ3 A;  5DLH A;  3T87 A;  3FU6 A;  3SE6 A;  3F28 A;  3CHS A;  5LG6 A;  4GAA A;  4KXC A;  3FUE A;  4QIR A;  3NQZ B;  4FCA A;  3MSF A;  5FXN A;  4JBS A;  3NN7 A;  4R5V A;  2A7G E;  5BPP A;  1PE8 A;  4R5X A;  3QNF A;  3FH8 A;  3MDJ A;  5JXN E;  4XN1 A;  4K5L A;  7TLI A;  5JSS E;  4XN2 A;  4Z7I A;  5JVI E;  4XMW A;  1ESP A;  3FH7 A;  4ZX4 A;  1TLP E;  1Z9G E;  4KX8 A;  3FBO A;  1OS0 A;  3FB0 A;  4XO4 A;  1NPC A;  4FYQ A;  4MWP E;  4N5P E;  5CU5 A;  4AR9 A;  3DO2 A;  1FJO A;  3LS7 A;  2DQM A;  3NQY B;  3T8F A;  3NQX A;  5JT9 E;  4FYT A;  3FUF A;  3FU5 A;  4AR1 A;  5L8P E;  1LML A;  3B37 A;  1HS6 A;  5LIF E;  4OI5 E;  4FGM A;  3FCQ A;  3FLF A;  4X2U A;  3FUN A;  8TLI A;  4AR8 A;  1TLX A;  3FV4 A;  5L41 E;  2VJ8 A;  2DQ6 A;  3EBI A;  1LNC E;  3DBK A;  5TLN A;  4WZ9 A;  4R5T A;  5EV7 A;  3T8D A;  4XO5 A;  1GXW A;  3T74 A;  3B7T A;  3FTS A;  1L3F E;  3FUI A;  4FYS A;  5DLL A;  4XMZ A;  1LNA E;  4K5N A;  4ZX3 A;  3FH5 A;  4D9W A;  4FKH A;  4PVB A;  3T8G A;  5J6S A;  3FTW A;  5FSS A;  3FTV A;  2XQ0 A;  1LNB E;  5K7T A;  2WHZ A;  3FOR A;  4XMX A;  4TMN E;  3MSN A;  4P8Q A;  3T2I E;  2XPY A;  3FTX A;  3FUD A;  1QF2 A;  2YD0 A;  4NAQ A;  3CHO A;  3FUH A;  5K1V A;  4QHP A;  4ZW6 A;  4GER A;  4D91 A;  1KRO A;  1TRL A;  4KX7 A;  4H57 A;  4XMT A;  4ZW7 A;  6TMN E;  4MXJ E;  1KR6 A;  4RVB A;  3P7W E;  4ZQT A;  1FJU A;  4PJ6 A;  2TLI A;  3Q7J A;  2WI0 A;  2XPZ A;  4F5C A;  3FU3 A;  1HYT A;  4MZN E;  3P7Q E;  5DPE E;  3B7U X;  4XMU A;  4PW4 A;  4KXD A;  5LDS A;  3FTY A;  4FKK A;  4RSY A;  1SQM A;  2HPT A;  3QJX A;  1THL A;  5L3U E;  4K5M A;  5AB0 A;  1KEI A;  1KS7 A;  4TNL A;  3P7U E;  3P7T E;  6TLI A;  4II7 A;  3Q44 A;  5TLI A;  3QH5 A;  4XMV A;  1FJT A;  4PU2 A;  5AEN A;  2VQX A;  8TLN E;  3B2P A;  1LND E;  3P7P E; 
#chains in the Genus database with same CATH homology
 4J3B A;  4XN7 A;  1ZDP E;  3P7R E;  4OW3 A;  4TLI A;  3EBG A;  2XPY A;  1QF1 A;  3CHQ A;  3FTX A;  3B7R L;  3FUD A;  1TLP E;  3P7S E;  2TMN E;  1QF2 A;  1Z9G E;  5LWD E;  2HPO A;  3FBO A;  3FTZ A;  1OS0 A;  3B34 A;  3FB0 A;  4MTW E;  3FU0 A;  1QF0 A;  3CHO A;  3FUH A;  1KL6 A;  5A3Y A;  4K89 A;  4QHP A;  4XO4 A;  4MS6 A;  3FUJ A;  4GER A;  4ZW6 A;  4Q4I A;  3CHP A;  4K5O A;  5FWQ A;  3CIA A;  4TLN A;  1KJO A;  3DO0 A;  1U4G A;  4N4E E;  3FHE A;  1TMN E;  4D91 A;  1NPC A;  1KRO A;  1TRL A;  3FUL A;  4ZW3 A;  4MWP E;  4N5P E;  7TLN A;  2ZXG A;  3T8C A;  1EZM A;  4K5P A;  5FSP A;  1LNE E;  4ZX6 A;  3TLI A;  3DO2 A;  1FJO A;  1KJP A;  3MSA A;  4H57 A;  3LS7 A;  4XMT A;  4ZW7 A;  2TLX A;  2DQM A;  1LNF E;  1BQB A;  1KR6 A;  4MXJ E;  4K90 A;  4R7L A;  4QPE A;  4RVB A;  3ZI6 A;  6TMN E;  3P7W E;  3QGO A;  5HQD A;  5DYF A;  4ZQT A;  4L2L A;  4DPR A;  1FJU A;  2R59 A;  3B3B A;  3CHR A;  4XN4 A;  3NQY B;  4XN9 A;  3B2X A;  3T8F A;  2TLI A;  2WI0 A;  4ZX5 A;  3NQX A;  5JT9 E;  2XPZ A;  3FUF A;  3U9W A;  3F2P A;  5DPF E;  3QH1 A;  3FU5 A;  4B52 A;  1FJV A;  3DNZ A;  1GW6 A;  5L8P E;  1LML A;  2GTQ A;  3T73 A;  3T8V A;  4XND A;  3B37 A;  3FU3 A;  1HS6 A;  1KKK A;  1HYT A;  4MZN E;  4OI5 E;  5LIF E;  3T8H A;  3KED A;  3PUU A;  3P7Q E;  1FJW A;  3MS3 A;  3FCQ A;  3FVP A;  3FLF A;  4XNA A;  4XN5 A;  5DPE E;  4X2U A;  3B7U X;  3FUN A;  4Q4E A;  8TLI A;  1KTO A;  1FJ3 A;  4PW4 A;  4XMU A;  1TLX A;  3FV4 A;  3FGD A;  2G4Z A;  5DLH A;  3T87 A;  5L41 E;  4ZX4 A;  3FU6 A;  2VJ8 A;  3FTY A;  3F28 A;  2DQ6 A;  3CHS A;  3EBI A;  5FSJ A;  1LNC E;  4GAA A;  4QME A;  4RSY A;  3FTU A;  3FUM A;  3T2I E;  1SQM A;  1PE5 A;  3DBK A;  4ZW5 A;  5TLN A;  3SSB A;  2HPT A;  3FUE A;  4QIR A;  3QJX A;  4ZW8 A;  3NQZ B;  3N21 A;  4R5T A;  3DO1 A;  3MSF A;  3FXP A;  5FXN A;  3T8D A;  4XO5 A;  1GXW A;  3TMN E;  5TMN E;  4XN8 A;  3NN7 A;  1Y3G E;  3Q43 A;  3B7T A;  3T74 A;  3FTS A;  2A7G E;  4R5V A;  4QUO A;  1L3F E;  5BPP A;  1THL A;  3EBH A;  5L3U E;  3FUI A;  5DLL A;  4K5M A;  4XMZ A;  1LNA E;  1PE8 A;  4K5N A;  4ZX3 A;  1KEI A;  3FH5 A;  1KS7 A;  5JS3 E;  4TNL A;  3B7S A;  4R5X A;  3P7U E;  4XO3 A;  4M65 A;  1PE7 A;  4D9W A;  4XNB A;  3P7T E;  6TLI A;  3FUK A;  3FH8 A;  4MKT A;  4N66 E;  1H19 A;  5JXN E;  4XN1 A;  3EIM A;  3Q44 A;  3T8G A;  4K5L A;  4PVB A;  5TLI A;  3FTW A;  3T2H E;  7TLI A;  3QH5 A;  1TLI A;  4XMV A;  3FTV A;  5FSS A;  1FJT A;  2XQ0 A;  4PU2 A;  4XN2 A;  2VQX A;  5AEN A;  5JSS E;  1LNB E;  5K7T A;  1FJQ A;  2WHZ A;  3FOR A;  3T2J E;  3FXS A;  4XMX A;  5JVI E;  4XMW A;  4TMN E;  3MSN A;  8TLN E;  3B2P A;  3P7V E;  1LND E;  3P7P E;  1ESP A;  3FH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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