3F2PA

Thermolysin inhibition
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGDGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSEMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragment-Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Thermolysin
total genus 118
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 2008-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
A PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 3f2pA02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 3f2pA01
4ZX3A 1FJOA 3CHQA 1FJVA 4PU2A 1TMNE 4RVBA 4XN5A 5A3YA 2VQXA 3T8CA 5JXNE 2WI0A 5JS3E 1FJQA 3U9WA 3FTUA 4J3BA 8TLIA 4XN1A 4ZX5A 4OI5E 4MKTA 4XMZA 1EZMA 5LIFE 4MZNE 5HQDA 4ZW3A 3F28A 1GXWA 3FTZA 4MTWE 3FH8A 4X2UA 1HYTA 1KJOA 1TRLA 3FTWA 1Y3GE 3B37A 3CHOA 3N21A 3KEDA 1ZDPE 4K5PA 3P7VE 3P7SE 4XN9A 3SSBA 3FUKA 1KS7A 2ZXGA 3DO2A 3FULA 3FH7A 5FXNA 2TMNE 4M65A 4XN8A 1PE7A 1L3FE 3T8DA 3T8HA 3FHEA 3T8FA 1KR6A 3T2IE 3FV4A 4ZQTA 1TLIA 7TLNA 1FJUA 4XMTA 4ZW5A 3B7TA 3FU6A 1LNCE 2XPZA 3FU5A 3Q44A 4QPEA 4MXJE 1KL6A 4GERA 3T87A 3B34A 8TLNE 3QGOA 4PVBA 4XO4A 1KTOA 4K89A 3F2PA 3FCQA 1PE5A 1QF1A 3CHSA 4R5XA 4N66E 4Q4IA 3NQYB 1LNDE 3FUHA 3FLFA 5L8PE 2XPYA 5FSJA 1TLPE 3FGDA 3MSNA 2XQ0A 3FTVA 4K5NA 3FVPA 1QF2A 1TLXA 3DO1A 3NQXA 4R5VA 4XO3A 1Z9GE 4XMVA 5DLHA 3P7UE 3FXPA 4K5MA 4MS6A 3QH5A 1BQBA 3FXSA 1U4GA 3FUJA 4TNLA 4XO5A 4L2LA 4K5OA 2HPTA 3T73A 1FJTA 4D9WA 3FORA 4OW3A 3B2PA 3FU3A 4RSYA 6TMNE 4K5LA 4TMNE 4ZW6A 4ZX6A 3Q43A 3B7UX 4R5TA 3EBGA 1HS6A 3T2HE 3MSFA 2DQMA 3DBKA 3EBIA 3P7PE 4K90A 4ZX4A 3DNZA 4H57A 5JVIE 4PW4A 3MSAA 4N5PE 3EBHA 1QF0A 1LNAE 4Q4EA 5DYFA 3FUFA 4MWPE 3NN7A 3CHRA 4XMWA 4QUOA 3QH1A 4XMXA 5BPPA 1KROA 3FUNA 1LNEE 4XNAA 2R59A 1GW6A 1LNBE 4QIRA 5DPEE 1KEIA 3FUEA 5TMNE 4ZW7A 4XN4A 1KJPA 3CIAA 3PUUA 4XNBA 3T8VA 3T74A 3FH5A 4DPRA 4N4EE 2GTQA 5DLLA 4XN7A 5L3UE 2TLIA 4QHPA 2HPOA 3P7QE 3B2XA 4XNDA 4QMEA 2VJ8A 3P7RE 3QJXA 3MS3A 5FSSA 3T8GA 1H19A 4TLNA 5JSSE 5AENA 5JT9E 3FTSA 3FB0A 3B7RL 5DPFE 4D91A 4R7LA 5K7TA 1LNFE 2DQ6A 3B3BA 3FTYA 3FBOA 3T2JE 3CHPA 3EIMA 2TLXA 2A7GE 1KKKA 5TLNA 1OS0A 3B7SA 3FTXA 1NPCA 3FUDA 4XN2A 3ZI6A 7TLIA 2G4ZA 5L41E 1THLA 1SQMA 3DO0A 6TLIA 3P7TE 3FU0A 3TLIA 4B52A 3P7WE 5FWQA 1FJWA 1ESPA 4XMUA 5LWDE 3LS7A 3NQZB 5FSPA 1FJ3A 3FUIA 1PE8A 2WHZA 5TLIA 3FUMA 4GAAA 4TLIA 3TMNE 4ZW8A
chains in the Genus database with same CATH superfamily
4ZX3A 1FJOA 3CHQA 5LDSA 1FJVA 4PU2A 1TMNE 4RVBA 4XN5A 5A3YA 2VQXA 3T8CA 5JXNE 2WI0A 5JS3E 1FJQA 3U9WA 3FTUA 4J3BA 8TLIA 4XN1A 4ZX5A 4OI5E 4MKTA 4XMZA 1EZMA 5LIFE 4MZNE 5HQDA 4ZW3A 3F28A 1GXWA 3FTZA 4MTWE 3FH8A 4X2UA 3SSBA 1HYTA 1KJOA 1TRLA 3FTWA 5K1VA 1Y3GE 3B37A 3CHOA 3N21A 3KEDA 1ZDPE 4FYTA 3P7VE 3P7SE 4FYSA 4K5PA 4OU3A 3FUKA 1KS7A 2ZXGA 3DO2A 3FULA 3FH7A 4XN9A 5FXNA 4P8QA 2TMNE 4M65A 4XN8A 1PE7A 1L3FE 3T8DA 3T8HA 3FHEA 3T8FA 4FKHA 1KR6A 3T2IE 3FV4A 4ZQTA 1TLIA 7TLNA 1FJUA 4XMTA 4ZW5A 5AB2A 3B7TA 3FU6A 4PJ6A 1LNCE 2XPZA 3FU5A 3Q44A 4QPEA 4MXJE 1KL6A 4GERA 3T87A 3B34A 8TLNE 3QGOA 4PVBA 4XO4A 1KTOA 4K89A 3F2PA 3FCQA 4AR8A 1PE5A 1QF1A 3CHSA 4R5XA 4N66E 4Q4IA 3NQYB 1LNDE 3FUHA 3FLFA 5L8PE 2XPYA 5FSJA 1TLPE 3FGDA 3MSNA 2XQ0A 3FTVA 3MDJA 4K5NA 4KXAA 3FVPA 1QF2A 1TLXA 3DO1A 4NZ8A 3NQXA 4R5VA 4XO3A 4AR9A 1Z9GE 4XMVA 5DLHA 3P7UE 3FXPA 4K5MA 4MS6A 3QH5A 1BQBA 3FXSA 1U4GA 3FUJA 4TNLA 4XO5A 4L2LA 4K5OA 2HPTA 3T73A 1FJTA 4D9WA 2YD0A 3FORA 4OW3A 4F5CA 3B2PA 3FU3A 4RSYA 6TMNE 4K5LA 4IHQA 4KXCA 4KXBA 4TMNE 4ZW6A 4ZX6A 3Q43A 3B7UX 4R5TA 3EBGA 1HS6A 3T2HE 3MSFA 2DQMA 3DBKA 1Z5HA 3EBIA 3P7PE 4K90A 3DNZA 4H57A 4ZX4A 5C97A 4PW4A 5JVIE 3MSAA 4N5PE 3SE6A 3EBHA 1QF0A 1LNAE 4Q4EA 4WZ9A 4FKEA 5DYFA 3FUFA 4MWPE 4Z7IA 5J6SA 3NN7A 3CHRA 4FGMA 4AR1A 4XMWA 3Q7JA 4QUOA 3QH1A 4XMXA 5BPPA 1KROA 3FUNA 1LNEE 4E36A 4XNAA 2R59A 1GW6A 1LNBE 4QIRA 5DPEE 1KEIA 3FUEA 5TMNE 4ZW7A 4XN4A 1KJPA 3CIAA 3PUUA 4XNBA 3T8VA 5AB0A 4ZW8A 3T74A 4II7A 3FH5A 4DPRA 4N4EE 2GTQA 5DLLA 4XN7A 4KX7A 5L3UE 2TLIA 4KX8A 2HPOA 3P7QE 3B2XA 4QHPA 5LG6A 4XNDA 4FYQA 2VJ8A 3P7RE 3QJXA 3MS3A 4QMEA 5EV7A 1H19A 4TLNA 5FSSA 3T8GA 5AENA 5JSSE 5JT9E 3FTSA 4NAQA 3FB0A 3B7RL 5DPFE 4D91A 4JBSA 4R7LA 5K7TA 1LNFE 2DQ6A 3B3BA 3FTYA 3FBOA 3T2JE 3CHPA 3EIMA 2TLXA 1Z1WA 4FYRA 2A7GE 1KKKA 4FCAA 4KX9A 4HOMA 5TLNA 1OS0A 3B7SA 3FTXA 1NPCA 3FUDA 4XN2A 3ZI6A 7TLIA 2G4ZA 4ARFA 1THLA 1SQMA 3DO0A 4KXDA 6TLIA 5L41E 3P7TE 3FU0A 3TLIA 4B52A 5LHDA 3P7WE 5FWQA 1FJWA 1ESPA 4XMUA 5LWDE 3LS7A 3NQZB 5FSPA 1FJ3A 3FUIA 1PE8A 2WHZA 5TLIA 1LMLA 3FUMA 4GAAA 4FKKA 4TLIA 3QNFA 3TMNE 5CU5A
chains in the Genus database with same CATH topology
4ZX3A 1FJOA 3CHQA 1FJVA 4PU2A 1TMNE 4RVBA 4XN5A 5A3YA 2VQXA 3T8CA 5JXNE 2WI0A 5JS3E 1FJQA 3U9WA 3FTUA 4J3BA 8TLIA 4XN1A 4ZX5A 4OI5E 4MKTA 4XMZA 1EZMA 5LIFE 4MZNE 5HQDA 4ZW3A 3F28A 1GXWA 3FTZA 4MTWE 3FH8A 4X2UA 1HYTA 1KJOA 1TRLA 3FTWA 1Y3GE 3B37A 3CHOA 3N21A 3KEDA 1ZDPE 4K5PA 3P7VE 3P7SE 4XN9A 3SSBA 3FUKA 1KS7A 2ZXGA 3DO2A 3FULA 3FH7A 5FXNA 2TMNE 4M65A 4XN8A 1PE7A 1L3FE 3T8DA 3T8HA 3FHEA 3T8FA 1KR6A 3T2IE 3FV4A 4ZQTA 1TLIA 7TLNA 1FJUA 4XMTA 4ZW5A 3B7TA 3FU6A 1LNCE 2XPZA 3FU5A 3Q44A 4QPEA 4MXJE 1KL6A 4GERA 3T87A 3B34A 8TLNE 3QGOA 4PVBA 4XO4A 1KTOA 4K89A 3F2PA 3FCQA 1PE5A 1QF1A 3CHSA 4R5XA 4N66E 4Q4IA 3NQYB 1LNDE 3FUHA 3FLFA 5L8PE 2XPYA 5FSJA 1TLPE 3FGDA 3MSNA 2XQ0A 3FTVA 4K5NA 3FVPA 1QF2A 1TLXA 3DO1A 3NQXA 4R5VA 4XO3A 1Z9GE 4XMVA 5DLHA 3P7UE 3FXPA 4K5MA 4MS6A 3QH5A 1BQBA 3FXSA 1U4GA 3FUJA 4TNLA 4XO5A 4L2LA 4K5OA 2HPTA 3T73A 1FJTA 4D9WA 3FORA 4OW3A 3B2PA 3FU3A 4RSYA 6TMNE 4K5LA 4TMNE 4ZW6A 4ZX6A 3Q43A 3B7UX 4R5TA 3EBGA 1HS6A 3T2HE 3MSFA 2DQMA 3DBKA 3EBIA 3P7PE 4K90A 4ZX4A 3DNZA 4H57A 5JVIE 4PW4A 3MSAA 4N5PE 3EBHA 1QF0A 1LNAE 4Q4EA 5DYFA 3FUFA 4MWPE 3NN7A 3CHRA 4XMWA 4QUOA 3QH1A 4XMXA 5BPPA 1KROA 3FUNA 1LNEE 4XNAA 2R59A 1GW6A 1LNBE 4QIRA 5DPEE 1KEIA 3FUEA 5TMNE 4ZW7A 4XN4A 1KJPA 3CIAA 3PUUA 4XNBA 3T8VA 3T74A 3FH5A 4DPRA 4N4EE 2GTQA 5DLLA 4XN7A 5L3UE 2TLIA 4QHPA 2HPOA 3P7QE 3B2XA 4XNDA 4QMEA 2VJ8A 3P7RE 3QJXA 3MS3A 5FSSA 3T8GA 1H19A 4TLNA 5JSSE 5AENA 5JT9E 3FTSA 3FB0A 3B7RL 5DPFE 4D91A 4R7LA 5K7TA 1LNFE 2DQ6A 3B3BA 3FTYA 3FBOA 3T2JE 3CHPA 3EIMA 2TLXA 2A7GE 1KKKA 5TLNA 1OS0A 3B7SA 3FTXA 1NPCA 3FUDA 4XN2A 3ZI6A 7TLIA 2G4ZA 5L41E 1THLA 1SQMA 3DO0A 6TLIA 3P7TE 3FU0A 3TLIA 4B52A 3P7WE 5FWQA 1FJWA 1ESPA 4XMUA 5LWDE 3LS7A 3NQZB 5FSPA 1FJ3A 3FUIA 1PE8A 2WHZA 5TLIA 1LMLA 3FUMA 4GAAA 4TLIA 3TMNE 4ZW8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZX3 A;  1FJO A;  3CHQ A;  1FJV A;  4PU2 A;  1TMN E;  4RVB A;  4XN5 A;  5A3Y A;  2VQX A;  3T8C A;  5JXN E;  2WI0 A;  5JS3 E;  1FJQ A;  3U9W A;  3FTU A;  4J3B A;  8TLI A;  4XN1 A;  4ZX5 A;  4OI5 E;  4MKT A;  4XMZ A;  1EZM A;  5LIF E;  4MZN E;  5HQD A;  4ZW3 A;  3F28 A;  1GXW A;  3FTZ A;  4MTW E;  3FH8 A;  4X2U A;  1HYT A;  1KJO A;  1TRL A;  3FTW A;  1Y3G E;  3B37 A;  3CHO A;  3N21 A;  3KED A;  1ZDP E;  4K5P A;  3P7V E;  3P7S E;  4XN9 A;  3SSB A;  3FUK A;  1KS7 A;  2ZXG A;  3DO2 A;  3FUL A;  3FH7 A;  5FXN A;  2TMN E;  4M65 A;  4XN8 A;  1PE7 A;  1L3F E;  3T8D A;  3T8H A;  3FHE A;  3T8F A;  1KR6 A;  3T2I E;  3FV4 A;  4ZQT A;  1TLI A;  7TLN A;  1FJU A;  4XMT A;  4ZW5 A;  3B7T A;  3FU6 A;  1LNC E;  2XPZ A;  3FU5 A;  3Q44 A;  4QPE A;  4MXJ E;  1KL6 A;  4GER A;  3T87 A;  3B34 A;  8TLN E;  3QGO A;  4PVB A;  4XO4 A;  1KTO A;  4K89 A;  3F2P A;  3FCQ A;  1PE5 A;  1QF1 A;  3CHS A;  4R5X A;  4N66 E;  4Q4I A;  3NQY B;  1LND E;  3FUH A;  3FLF A;  5L8P E;  2XPY A;  5FSJ A;  1TLP E;  3FGD A;  3MSN A;  2XQ0 A;  3FTV A;  4K5N A;  3FVP A;  1QF2 A;  1TLX A;  3DO1 A;  3NQX A;  4R5V A;  4XO3 A;  1Z9G E;  4XMV A;  5DLH A;  3P7U E;  3FXP A;  4K5M A;  4MS6 A;  3QH5 A;  1BQB A;  3FXS A;  1U4G A;  3FUJ A;  4TNL A;  4XO5 A;  4L2L A;  4K5O A;  2HPT A;  3T73 A;  1FJT A;  4D9W A;  3FOR A;  4OW3 A;  3B2P A;  3FU3 A;  4RSY A;  6TMN E;  4K5L A;  4TMN E;  4ZW6 A;  4ZX6 A;  3Q43 A;  3B7U X;  4R5T A;  3EBG A;  1HS6 A;  3T2H E;  3MSF A;  2DQM A;  3DBK A;  3EBI A;  3P7P E;  4K90 A;  4ZX4 A;  3DNZ A;  4H57 A;  5JVI E;  4PW4 A;  3MSA A;  4N5P E;  3EBH A;  1QF0 A;  1LNA E;  4Q4E A;  5DYF A;  3FUF A;  4MWP E;  3NN7 A;  3CHR A;  4XMW A;  4QUO A;  3QH1 A;  4XMX A;  5BPP A;  1KRO A;  3FUN A;  1LNE E;  4XNA A;  2R59 A;  1GW6 A;  1LNB E;  4QIR A;  5DPE E;  1KEI A;  3FUE A;  5TMN E;  4ZW7 A;  4XN4 A;  1KJP A;  3CIA A;  3PUU A;  4XNB A;  3T8V A;  3T74 A;  3FH5 A;  4DPR A;  4N4E E;  2GTQ A;  5DLL A;  4XN7 A;  5L3U E;  2TLI A;  4QHP A;  2HPO A;  3P7Q E;  3B2X A;  4XND A;  4QME A;  2VJ8 A;  3P7R E;  3QJX A;  3MS3 A;  5FSS A;  3T8G A;  1H19 A;  4TLN A;  5JSS E;  5AEN A;  5JT9 E;  3FTS A;  3FB0 A;  3B7R L;  5DPF E;  4D91 A;  4R7L A;  5K7T A;  1LNF E;  2DQ6 A;  3B3B A;  3FTY A;  3FBO A;  3T2J E;  3CHP A;  3EIM A;  2TLX A;  2A7G E;  1KKK A;  5TLN A;  1OS0 A;  3B7S A;  3FTX A;  1NPC A;  3FUD A;  4XN2 A;  3ZI6 A;  7TLI A;  2G4Z A;  5L41 E;  1THL A;  1SQM A;  3DO0 A;  6TLI A;  3P7T E;  3FU0 A;  3TLI A;  4B52 A;  3P7W E;  5FWQ A;  1FJW A;  1ESP A;  4XMU A;  5LWD E;  3LS7 A;  3NQZ B;  5FSP A;  1FJ3 A;  3FUI A;  1PE8 A;  2WHZ A;  5TLI A;  3FUM A;  4GAA A;  4TLI A;  3TMN E;  4ZW8 A; 
#chains in the Genus database with same CATH topology
 4ZX3 A;  1FJO A;  3CHQ A;  5LDS A;  1FJV A;  4PU2 A;  1TMN E;  4RVB A;  4XN5 A;  5A3Y A;  2VQX A;  3T8C A;  5JXN E;  2WI0 A;  5JS3 E;  1FJQ A;  3U9W A;  3FTU A;  4J3B A;  8TLI A;  4XN1 A;  4ZX5 A;  4OI5 E;  4MKT A;  4XMZ A;  1EZM A;  5LIF E;  4MZN E;  5HQD A;  4ZW3 A;  3F28 A;  1GXW A;  3FTZ A;  4MTW E;  3FH8 A;  4X2U A;  3SSB A;  1HYT A;  1KJO A;  1TRL A;  3FTW A;  5K1V A;  1Y3G E;  3B37 A;  3CHO A;  3N21 A;  3KED A;  1ZDP E;  4FYT A;  3P7V E;  3P7S E;  4FYS A;  4K5P A;  4OU3 A;  3FUK A;  1KS7 A;  2ZXG A;  3DO2 A;  3FUL A;  3FH7 A;  4XN9 A;  5FXN A;  4P8Q A;  2TMN E;  4M65 A;  4XN8 A;  1PE7 A;  1L3F E;  3T8D A;  3T8H A;  3FHE A;  3T8F A;  4FKH A;  1KR6 A;  3T2I E;  3FV4 A;  4ZQT A;  1TLI A;  7TLN A;  1FJU A;  4XMT A;  4ZW5 A;  5AB2 A;  3B7T A;  3FU6 A;  4PJ6 A;  1LNC E;  2XPZ A;  3FU5 A;  3Q44 A;  4QPE A;  4MXJ E;  1KL6 A;  4GER A;  3T87 A;  3B34 A;  8TLN E;  3QGO A;  4PVB A;  4XO4 A;  1KTO A;  4K89 A;  3F2P A;  3FCQ A;  4AR8 A;  1PE5 A;  1QF1 A;  3CHS A;  4R5X A;  4N66 E;  4Q4I A;  3NQY B;  1LND E;  3FUH A;  3FLF A;  5L8P E;  2XPY A;  5FSJ A;  1TLP E;  3FGD A;  3MSN A;  2XQ0 A;  3FTV A;  3MDJ A;  4K5N A;  4KXA A;  3FVP A;  1QF2 A;  1TLX A;  3DO1 A;  4NZ8 A;  3NQX A;  4R5V A;  4XO3 A;  4AR9 A;  1Z9G E;  4XMV A;  5DLH A;  3P7U E;  3FXP A;  4K5M A;  4MS6 A;  3QH5 A;  1BQB A;  3FXS A;  1U4G A;  3FUJ A;  4TNL A;  4XO5 A;  4L2L A;  4K5O A;  2HPT A;  3T73 A;  1FJT A;  4D9W A;  2YD0 A;  3FOR A;  4OW3 A;  4F5C A;  3B2P A;  3FU3 A;  4RSY A;  6TMN E;  4K5L A;  4IHQ A;  4KXC A;  4KXB A;  4TMN E;  4ZW6 A;  4ZX6 A;  3Q43 A;  3B7U X;  4R5T A;  3EBG A;  1HS6 A;  3T2H E;  3MSF A;  2DQM A;  3DBK A;  1Z5H A;  3EBI A;  3P7P E;  4K90 A;  3DNZ A;  4H57 A;  4ZX4 A;  5C97 A;  4PW4 A;  5JVI E;  3MSA A;  4N5P E;  3SE6 A;  3EBH A;  1QF0 A;  1LNA E;  4Q4E A;  4WZ9 A;  4FKE A;  5DYF A;  3FUF A;  4MWP E;  4Z7I A;  5J6S A;  3NN7 A;  3CHR A;  4FGM A;  4AR1 A;  4XMW A;  3Q7J A;  4QUO A;  3QH1 A;  4XMX A;  5BPP A;  1KRO A;  3FUN A;  1LNE E;  4E36 A;  4XNA A;  2R59 A;  1GW6 A;  1LNB E;  4QIR A;  5DPE E;  1KEI A;  3FUE A;  5TMN E;  4ZW7 A;  4XN4 A;  1KJP A;  3CIA A;  3PUU A;  4XNB A;  3T8V A;  5AB0 A;  4ZW8 A;  3T74 A;  4II7 A;  3FH5 A;  4DPR A;  4N4E E;  2GTQ A;  5DLL A;  4XN7 A;  4KX7 A;  5L3U E;  2TLI A;  4KX8 A;  2HPO A;  3P7Q E;  3B2X A;  4QHP A;  5LG6 A;  4XND A;  4FYQ A;  2VJ8 A;  3P7R E;  3QJX A;  3MS3 A;  4QME A;  5EV7 A;  1H19 A;  4TLN A;  5FSS A;  3T8G A;  5AEN A;  5JSS E;  5JT9 E;  3FTS A;  4NAQ A;  3FB0 A;  3B7R L;  5DPF E;  4D91 A;  4JBS A;  4R7L A;  5K7T A;  1LNF E;  2DQ6 A;  3B3B A;  3FTY A;  3FBO A;  3T2J E;  3CHP A;  3EIM A;  2TLX A;  1Z1W A;  4FYR A;  2A7G E;  1KKK A;  4FCA A;  4KX9 A;  4HOM A;  5TLN A;  1OS0 A;  3B7S A;  3FTX A;  1NPC A;  3FUD A;  4XN2 A;  3ZI6 A;  7TLI A;  2G4Z A;  4ARF A;  1THL A;  1SQM A;  3DO0 A;  4KXD A;  6TLI A;  5L41 E;  3P7T E;  3FU0 A;  3TLI A;  4B52 A;  5LHD A;  3P7W E;  5FWQ A;  1FJW A;  1ESP A;  4XMU A;  5LWD E;  3LS7 A;  3NQZ B;  5FSP A;  1FJ3 A;  3FUI A;  1PE8 A;  2WHZ A;  5TLI A;  1LML A;  3FUM A;  4GAA A;  4FKK A;  4TLI A;  3QNF A;  3TMN E;  5CU5 A; 
#chains in the Genus database with same CATH homology
 4ZX3 A;  1FJO A;  3CHQ A;  1FJV A;  4PU2 A;  1TMN E;  4RVB A;  4XN5 A;  5A3Y A;  2VQX A;  3T8C A;  5JXN E;  2WI0 A;  5JS3 E;  1FJQ A;  3U9W A;  3FTU A;  4J3B A;  8TLI A;  4XN1 A;  4ZX5 A;  4OI5 E;  4MKT A;  4XMZ A;  1EZM A;  5LIF E;  4MZN E;  5HQD A;  4ZW3 A;  3F28 A;  1GXW A;  3FTZ A;  4MTW E;  3FH8 A;  4X2U A;  1HYT A;  1KJO A;  1TRL A;  3FTW A;  1Y3G E;  3B37 A;  3CHO A;  3N21 A;  3KED A;  1ZDP E;  4K5P A;  3P7V E;  3P7S E;  4XN9 A;  3SSB A;  3FUK A;  1KS7 A;  2ZXG A;  3DO2 A;  3FUL A;  3FH7 A;  5FXN A;  2TMN E;  4M65 A;  4XN8 A;  1PE7 A;  1L3F E;  3T8D A;  3T8H A;  3FHE A;  3T8F A;  1KR6 A;  3T2I E;  3FV4 A;  4ZQT A;  1TLI A;  7TLN A;  1FJU A;  4XMT A;  4ZW5 A;  3B7T A;  3FU6 A;  1LNC E;  2XPZ A;  3FU5 A;  3Q44 A;  4QPE A;  4MXJ E;  1KL6 A;  4GER A;  3T87 A;  3B34 A;  8TLN E;  3QGO A;  4PVB A;  4XO4 A;  1KTO A;  4K89 A;  3F2P A;  3FCQ A;  1PE5 A;  1QF1 A;  3CHS A;  4R5X A;  4N66 E;  4Q4I A;  3NQY B;  1LND E;  3FUH A;  3FLF A;  5L8P E;  2XPY A;  5FSJ A;  1TLP E;  3FGD A;  3MSN A;  2XQ0 A;  3FTV A;  4K5N A;  3FVP A;  1QF2 A;  1TLX A;  3DO1 A;  3NQX A;  4R5V A;  4XO3 A;  1Z9G E;  4XMV A;  5DLH A;  3P7U E;  3FXP A;  4K5M A;  4MS6 A;  3QH5 A;  1BQB A;  3FXS A;  1U4G A;  3FUJ A;  4TNL A;  4XO5 A;  4L2L A;  4K5O A;  2HPT A;  3T73 A;  1FJT A;  4D9W A;  3FOR A;  4OW3 A;  3B2P A;  3FU3 A;  4RSY A;  6TMN E;  4K5L A;  4TMN E;  4ZW6 A;  4ZX6 A;  3Q43 A;  3B7U X;  4R5T A;  3EBG A;  1HS6 A;  3T2H E;  3MSF A;  2DQM A;  3DBK A;  3EBI A;  3P7P E;  4K90 A;  4ZX4 A;  3DNZ A;  4H57 A;  5JVI E;  4PW4 A;  3MSA A;  4N5P E;  3EBH A;  1QF0 A;  1LNA E;  4Q4E A;  5DYF A;  3FUF A;  4MWP E;  3NN7 A;  3CHR A;  4XMW A;  4QUO A;  3QH1 A;  4XMX A;  5BPP A;  1KRO A;  3FUN A;  1LNE E;  4XNA A;  2R59 A;  1GW6 A;  1LNB E;  4QIR A;  5DPE E;  1KEI A;  3FUE A;  5TMN E;  4ZW7 A;  4XN4 A;  1KJP A;  3CIA A;  3PUU A;  4XNB A;  3T8V A;  3T74 A;  3FH5 A;  4DPR A;  4N4E E;  2GTQ A;  5DLL A;  4XN7 A;  5L3U E;  2TLI A;  4QHP A;  2HPO A;  3P7Q E;  3B2X A;  4XND A;  4QME A;  2VJ8 A;  3P7R E;  3QJX A;  3MS3 A;  5FSS A;  3T8G A;  1H19 A;  4TLN A;  5JSS E;  5AEN A;  5JT9 E;  3FTS A;  3FB0 A;  3B7R L;  5DPF E;  4D91 A;  4R7L A;  5K7T A;  1LNF E;  2DQ6 A;  3B3B A;  3FTY A;  3FBO A;  3T2J E;  3CHP A;  3EIM A;  2TLX A;  2A7G E;  1KKK A;  5TLN A;  1OS0 A;  3B7S A;  3FTX A;  1NPC A;  3FUD A;  4XN2 A;  3ZI6 A;  7TLI A;  2G4Z A;  5L41 E;  1THL A;  1SQM A;  3DO0 A;  6TLI A;  3P7T E;  3FU0 A;  3TLI A;  4B52 A;  3P7W E;  5FWQ A;  1FJW A;  1ESP A;  4XMU A;  5LWD E;  3LS7 A;  3NQZ B;  5FSP A;  1FJ3 A;  3FUI A;  1PE8 A;  2WHZ A;  5TLI A;  1LML A;  3FUM A;  4GAA A;  4TLI A;  3TMN E;  4ZW8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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