3MSFA

Crystal structure of thermolysin in complex with urea
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Thermolysin
publication title Experimental and computational active site mapping as a starting point to fragment-based lead discovery.
pubmed doi rcsb
molecule tags Hydrolase
total genus 117
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 2010-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
A PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 3msfA02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 3msfA01
3SSBA 3EBGA 5FXNA 3FH7A 3FUMA 4OW3A 5DLLA 3TMNE 3P7RE 3QH5A 4GERA 4OI5E 3FU3A 2TMNE 5AENA 4XN7A 3FTZA 4K5OA 5FSPA 4K89A 4ZW3A 4R5XA 3N21A 3T2HE 5JSSE 4XNDA 3FUFA 3U9WA 2VQXA 5JVIE 4XN5A 1QF0A 4ZX3A 4DPRA 4QPEA 3T8DA 2XPYA 3FTYA 1H19A 3B37A 5DPFE 5TLNA 3T8FA 3FORA 3TLIA 3Q43A 4K5LA 1L3FE 3P7UE 5L3UE 3CHQA 1FJQA 3FLFA 3F2PA 3FH5A 3FTWA 4R7LA 3FTSA 3FUDA 4XN2A 1EZMA 3FVPA 1KJOA 1Z9GE 4XMVA 4D9WA 2DQ6A 1KJPA 4B52A 4GAAA 1KS7A 5FWQA 5FSJA 3FU0A 3FUJA 3FU6A 4XNAA 3MS3A 1LNDE 1KL6A 4N4EE 3MSFA 4XMZA 3FV4A 1LNEE 3P7SE 3FTVA 3EBIA 3P7PE 3NQZB 3PUUA 2A7GE 4QUOA 4XN4A 4XMWA 1PE5A 4XNBA 4J3BA 4K90A 3QH1A 1FJVA 3T8GA 3ZI6A 1HYTA 2WI0A 4TLNA 4PU2A 3T2IE 3FUIA 1PE8A 2G4ZA 3QGOA 4XN1A 3FHEA 2ZXGA 3B2PA 1QF1A 2DQMA 3FGDA 3CHPA 2XPZA 3FUEA 4PVBA 5TLIA 4ZW5A 1LNAE 3NN7A 4ZW8A 3T87A 7TLIA 5HQDA 1GW6A 5DYFA 3T74A 3FTUA 3FUNA 4R5TA 4N66E 3T8CA 8TLIA 3B34A 3B2XA 3T8HA 4M65A 4QIRA 1FJ3A 2R59A 1NPCA 5JS3E 4ZX6A 8TLNE 3CHOA 4XO3A 4K5NA 1LNCE 4D91A 1BQBA 7TLNA 1LNBE 3FUKA 3KEDA 2HPOA 1QF2A 1KKKA 4ZW7A 2GTQA 4K5PA 3QJXA 2TLXA 4ZW6A 4H57A 1THLA 5DLHA 3B7UX 4XMXA 1LNFE 4XO4A 3P7WE 5DPEE 4N5PE 6TMNE 1U4GA 3B7SA 3FCQA 3NQYB 1KEIA 4RSYA 1FJUA 5JXNE 3LS7A 3DO0A 1Y3GE 3FULA 3CHRA 5BPPA 1TMNE 4XMUA 4TLIA 3NQXA 1FJTA 1TLIA 1KROA 6TLIA 1KTOA 3B7TA 1TLPE 4MKTA 4Q4IA 3P7VE 2VJ8A 3CHSA 5LIFE 3B7RL 3DO2A 4ZX5A 5A3YA 3MSNA 4MZNE 1KR6A 5FSSA 3T2JE 3DO1A 1OS0A 4R5VA 3FXSA 4PW4A 5LWDE 4XN9A 3FUHA 4X2UA 2HPTA 3EIMA 3DBKA 5L8PE 1SQMA 1TLXA 5K7TA 3Q44A 4QHPA 4MTWE 2WHZA 3FU5A 4MXJE 3F28A 4XO5A 3FH8A 3T73A 3CIAA 4XN8A 1PE7A 4MWPE 1GXWA 3DNZA 1HS6A 4MS6A 4ZX4A 3FB0A 3EBHA 4L2LA 4XMTA 3P7TE 3P7QE 3T8VA 4ZQTA 1FJOA 4Q4EA 4QMEA 3FXPA 1TRLA 4K5MA 3FBOA 4TMNE 5TMNE 5L41E 3B3BA 1ZDPE 2TLIA 4RVBA 1FJWA 5JT9E 3MSAA 2XQ0A 3FTXA 4TNLA 1ESPA
chains in the Genus database with same CATH superfamily
3SSBA 3TMNE 5FXNA 3FH7A 3FUMA 5C97A 4WZ9A 1Z1WA 4R5XA 3FUFA 3U9WA 4DPRA 3QNFA 3T8DA 3FTYA 1H19A 5TLNA 3P7UE 5L3UE 4KXCA 3FH5A 3FTWA 4R7LA 2DQ6A 4B52A 3FUJA 3FU6A 3MS3A 4KXDA 1KL6A 3FV4A 1LNEE 4XMWA 2A7GE 1PE5A 1FJVA 2WI0A 4PU2A 4FYSA 1PE8A 4XN1A 3FHEA 3B2PA 3FGDA 4FYQA 5CU5A 4PVBA 1LNAE 7TLIA 5HQDA 5DYFA 4QIRA 4KX8A 2R59A 8TLNE 3CHOA 4D91A 1KKKA 2GTQA 1THLA 1LNFE 4N5PE 3FULA 3CHRA 4TLIA 6TLIA 4MKTA 1KR6A 4X2UA 4FCAA 4KXAA 3CIAA 4XN8A 3DNZA 3EBHA 4L2LA 3P7QE 3T8VA 4Q4EA 4TMNE 5L41E 3B3BA 4RVBA 1FJWA 5JT9E 5L8PE 4OI5E 2TMNE 4XN7A 4K5OA 4P8QA 3N21A 5JVIE 1QF0A 4QPEA 3Q43A 3FLFA 3F2PA 3FTSA 4XN2A 4HOMA 1KJPA 4GAAA 3FU0A 4XNAA 4N4EE 3MSFA 4QUOA 3EBIA 3NQZB 4XNBA 3QH1A 4FKEA 3FUIA 2ZXGA 4NZ8A 4IHQA 1QF1A 2DQMA 1Z5HA 2XPZA 3FUEA 3NN7A 3SE6A 3T87A 3B2XA 3T8HA 4M65A 1FJ3A 5JS3E 4ZX6A 4FYTA 1LNBE 2HPOA 1QF2A 4ZW7A 1LMLA 4K5PA 3B7UX 5DPEE 4FGMA 6TMNE 3NQYB 4XMUA 1TLIA 1KROA 2VJ8A 3CHSA 3B7RL 5A3YA 3FUHA 2HPTA 3DBKA 3Q44A 4QHPA 3FH8A 4MS6A 3FB0A 3P7TE 4II7A 3FXPA 1TRLA 4K5MA 3FBOA 2XQ0A 5DLLA 3FTXA 7TLNA 1ESPA 3EBGA 4D9WA 3QH5A 3FTZA 5FSPA 2VQXA 4XN5A 4ZX3A 2XPYA 3T8FA 4K5LA 1FJQA 1EZMA 4XMZA 5LHDA 3PUUA 4XN4A 4K90A 3T8GA 1HYTA 3T2IE 4AR9A 5TLIA 4FKHA 3T74A 3FUNA 3T8CA 4AR1A 4XO3A 1LNCE 1BQBA 3KEDA 3MDJA 5LDSA 3QJXA 4FKKA 2TLXA 4ZW6A 5DLHA 4XMXA 4XO4A 5AB2A 1U4GA 3B7SA 3FCQA 4RSYA 1FJUA 5JXNE 5AB0A 3LS7A 3DO0A 5LG6A 5BPPA 1TMNE 3NQXA 1FJTA 4PJ6A 3MSNA 1OS0A 4R5VA 4OU3A 4KX7A 4E36A 1TLXA 4NAQA 4MTWE 3F28A 4XO5A 3T73A 1PE7A 1GXWA 4ZQTA 4Z7IA 1FJOA 4KX9A 5FSSA 4TNLA 4OW3A 3P7RE 4GERA 3FU3A 5AENA 4K89A 4ZW3A 5JSSE 4XNDA 3B37A 5DPFE 3FORA 3TLIA 1L3FE 3CHQA 3FUDA 3FVPA 1KJOA 1Z9GE 4XMVA 4ARFA 2YD0A 5FWQA 1KS7A 5FSJA 4KXBA 1LNDE 5J6SA 3T2HE 4AR8A 3P7SE 3FTVA 3P7PE 4J3BA 3ZI6A 4FYRA 4TLNA 2G4ZA 3QGOA 4F5CA 3CHPA 4ZW5A 3Q7JA 4ZW8A 1GW6A 3FTUA 4R5TA 4N66E 8TLIA 3B34A 1NPCA 4K5NA 3FUKA 5EV7A 4H57A 4JBSA 3P7WE 1KEIA 1Y3GE 1KTOA 3B7TA 1TLPE 4Q4IA 3P7VE 5LIFE 3DO2A 4ZX5A 4MZNE 3T2JE 3DO1A 3FXSA 4PW4A 5K1VA 5LWDE 4XN9A 1SQMA 5K7TA 2WHZA 3FU5A 4MXJE 4MWPE 1HS6A 4ZX4A 4XMTA 4QMEA 5TMNE 1ZDPE 2TLIA 3MSAA 3EIMA
chains in the Genus database with same CATH topology
3SSBA 3EBGA 5FXNA 3FH7A 3FUMA 4OW3A 5DLLA 3TMNE 3P7RE 3QH5A 4GERA 4OI5E 3FU3A 2TMNE 5AENA 4XN7A 3FTZA 4K5OA 5FSPA 4K89A 4ZW3A 4R5XA 3N21A 3T2HE 5JSSE 4XNDA 3FUFA 3U9WA 2VQXA 5JVIE 4XN5A 1QF0A 4ZX3A 4DPRA 4QPEA 3T8DA 2XPYA 3FTYA 1H19A 3B37A 5DPFE 5TLNA 3T8FA 3FORA 3TLIA 3Q43A 4K5LA 1L3FE 3P7UE 5L3UE 3CHQA 1FJQA 3FLFA 3F2PA 3FH5A 3FTWA 4R7LA 3FTSA 3FUDA 4XN2A 1EZMA 3FVPA 1KJOA 1Z9GE 4XMVA 4D9WA 2DQ6A 1KJPA 4B52A 4GAAA 1KS7A 5FWQA 5FSJA 3FU0A 3FUJA 3FU6A 4XNAA 3MS3A 1LNDE 1KL6A 4N4EE 3MSFA 4XMZA 3FV4A 1LNEE 3P7SE 3FTVA 3EBIA 3P7PE 3NQZB 3PUUA 2A7GE 4QUOA 4XN4A 4XMWA 1PE5A 4XNBA 4J3BA 4K90A 3QH1A 1FJVA 3T8GA 3ZI6A 1HYTA 2WI0A 4TLNA 4PU2A 3T2IE 3FUIA 1PE8A 2G4ZA 3QGOA 4XN1A 3FHEA 2ZXGA 3B2PA 1QF1A 2DQMA 3FGDA 3CHPA 2XPZA 3FUEA 4PVBA 5TLIA 4ZW5A 1LNAE 3NN7A 4ZW8A 3T87A 7TLIA 5HQDA 1GW6A 5DYFA 3T74A 3FTUA 3FUNA 4R5TA 4N66E 3T8CA 8TLIA 3B34A 3B2XA 3T8HA 4M65A 4QIRA 1FJ3A 2R59A 1NPCA 5JS3E 4ZX6A 8TLNE 3CHOA 4XO3A 4K5NA 1LNCE 4D91A 1BQBA 7TLNA 1LNBE 3FUKA 3KEDA 2HPOA 1QF2A 1KKKA 4ZW7A 2GTQA 4K5PA 1LMLA 3QJXA 2TLXA 4ZW6A 4H57A 1THLA 5DLHA 3B7UX 4XMXA 1LNFE 4XO4A 3P7WE 5DPEE 4N5PE 6TMNE 1U4GA 3B7SA 3FCQA 3NQYB 1KEIA 4RSYA 1FJUA 5JXNE 3LS7A 3DO0A 1Y3GE 3FULA 3CHRA 5BPPA 1TMNE 4XMUA 4TLIA 3NQXA 1FJTA 1TLIA 1KROA 6TLIA 1KTOA 3B7TA 1TLPE 4MKTA 4Q4IA 3P7VE 2VJ8A 3CHSA 5LIFE 3B7RL 3DO2A 4ZX5A 5A3YA 3MSNA 4MZNE 1KR6A 5FSSA 3T2JE 3DO1A 1OS0A 4R5VA 3FXSA 4PW4A 5LWDE 4XN9A 3FUHA 4X2UA 2HPTA 3EIMA 3DBKA 5L8PE 1SQMA 1TLXA 5K7TA 3Q44A 4QHPA 4MTWE 2WHZA 3FU5A 4MXJE 3F28A 4XO5A 3FH8A 3T73A 3CIAA 4XN8A 1PE7A 4MWPE 1GXWA 3DNZA 1HS6A 4MS6A 4ZX4A 3FB0A 3EBHA 4L2LA 4XMTA 3P7TE 3P7QE 3T8VA 4ZQTA 1FJOA 4Q4EA 4QMEA 3FXPA 1TRLA 4K5MA 3FBOA 4TMNE 5TMNE 5L41E 3B3BA 1ZDPE 2TLIA 4RVBA 1FJWA 5JT9E 3MSAA 2XQ0A 3FTXA 4TNLA 1ESPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SSB A;  3EBG A;  5FXN A;  3FH7 A;  3FUM A;  4OW3 A;  5DLL A;  3TMN E;  3P7R E;  3QH5 A;  4GER A;  4OI5 E;  3FU3 A;  2TMN E;  5AEN A;  4XN7 A;  3FTZ A;  4K5O A;  5FSP A;  4K89 A;  4ZW3 A;  4R5X A;  3N21 A;  3T2H E;  5JSS E;  4XND A;  3FUF A;  3U9W A;  2VQX A;  5JVI E;  4XN5 A;  1QF0 A;  4ZX3 A;  4DPR A;  4QPE A;  3T8D A;  2XPY A;  3FTY A;  1H19 A;  3B37 A;  5DPF E;  5TLN A;  3T8F A;  3FOR A;  3TLI A;  3Q43 A;  4K5L A;  1L3F E;  3P7U E;  5L3U E;  3CHQ A;  1FJQ A;  3FLF A;  3F2P A;  3FH5 A;  3FTW A;  4R7L A;  3FTS A;  3FUD A;  4XN2 A;  1EZM A;  3FVP A;  1KJO A;  1Z9G E;  4XMV A;  4D9W A;  2DQ6 A;  1KJP A;  4B52 A;  4GAA A;  1KS7 A;  5FWQ A;  5FSJ A;  3FU0 A;  3FUJ A;  3FU6 A;  4XNA A;  3MS3 A;  1LND E;  1KL6 A;  4N4E E;  3MSF A;  4XMZ A;  3FV4 A;  1LNE E;  3P7S E;  3FTV A;  3EBI A;  3P7P E;  3NQZ B;  3PUU A;  2A7G E;  4QUO A;  4XN4 A;  4XMW A;  1PE5 A;  4XNB A;  4J3B A;  4K90 A;  3QH1 A;  1FJV A;  3T8G A;  3ZI6 A;  1HYT A;  2WI0 A;  4TLN A;  4PU2 A;  3T2I E;  3FUI A;  1PE8 A;  2G4Z A;  3QGO A;  4XN1 A;  3FHE A;  2ZXG A;  3B2P A;  1QF1 A;  2DQM A;  3FGD A;  3CHP A;  2XPZ A;  3FUE A;  4PVB A;  5TLI A;  4ZW5 A;  1LNA E;  3NN7 A;  4ZW8 A;  3T87 A;  7TLI A;  5HQD A;  1GW6 A;  5DYF A;  3T74 A;  3FTU A;  3FUN A;  4R5T A;  4N66 E;  3T8C A;  8TLI A;  3B34 A;  3B2X A;  3T8H A;  4M65 A;  4QIR A;  1FJ3 A;  2R59 A;  1NPC A;  5JS3 E;  4ZX6 A;  8TLN E;  3CHO A;  4XO3 A;  4K5N A;  1LNC E;  4D91 A;  1BQB A;  7TLN A;  1LNB E;  3FUK A;  3KED A;  2HPO A;  1QF2 A;  1KKK A;  4ZW7 A;  2GTQ A;  4K5P A;  3QJX A;  2TLX A;  4ZW6 A;  4H57 A;  1THL A;  5DLH A;  3B7U X;  4XMX A;  1LNF E;  4XO4 A;  3P7W E;  5DPE E;  4N5P E;  6TMN E;  1U4G A;  3B7S A;  3FCQ A;  3NQY B;  1KEI A;  4RSY A;  1FJU A;  5JXN E;  3LS7 A;  3DO0 A;  1Y3G E;  3FUL A;  3CHR A;  5BPP A;  1TMN E;  4XMU A;  4TLI A;  3NQX A;  1FJT A;  1TLI A;  1KRO A;  6TLI A;  1KTO A;  3B7T A;  1TLP E;  4MKT A;  4Q4I A;  3P7V E;  2VJ8 A;  3CHS A;  5LIF E;  3B7R L;  3DO2 A;  4ZX5 A;  5A3Y A;  3MSN A;  4MZN E;  1KR6 A;  5FSS A;  3T2J E;  3DO1 A;  1OS0 A;  4R5V A;  3FXS A;  4PW4 A;  5LWD E;  4XN9 A;  3FUH A;  4X2U A;  2HPT A;  3EIM A;  3DBK A;  5L8P E;  1SQM A;  1TLX A;  5K7T A;  3Q44 A;  4QHP A;  4MTW E;  2WHZ A;  3FU5 A;  4MXJ E;  3F28 A;  4XO5 A;  3FH8 A;  3T73 A;  3CIA A;  4XN8 A;  1PE7 A;  4MWP E;  1GXW A;  3DNZ A;  1HS6 A;  4MS6 A;  4ZX4 A;  3FB0 A;  3EBH A;  4L2L A;  4XMT A;  3P7T E;  3P7Q E;  3T8V A;  4ZQT A;  1FJO A;  4Q4E A;  4QME A;  3FXP A;  1TRL A;  4K5M A;  3FBO A;  4TMN E;  5TMN E;  5L41 E;  3B3B A;  1ZDP E;  2TLI A;  4RVB A;  1FJW A;  5JT9 E;  3MSA A;  2XQ0 A;  3FTX A;  4TNL A;  1ESP A; 
#chains in the Genus database with same CATH topology
 3SSB A;  3TMN E;  5FXN A;  3FH7 A;  3FUM A;  5C97 A;  4WZ9 A;  1Z1W A;  4R5X A;  3FUF A;  3U9W A;  4DPR A;  3QNF A;  3T8D A;  3FTY A;  1H19 A;  5TLN A;  3P7U E;  5L3U E;  4KXC A;  3FH5 A;  3FTW A;  4R7L A;  2DQ6 A;  4B52 A;  3FUJ A;  3FU6 A;  3MS3 A;  4KXD A;  1KL6 A;  3FV4 A;  1LNE E;  4XMW A;  2A7G E;  1PE5 A;  1FJV A;  2WI0 A;  4PU2 A;  4FYS A;  1PE8 A;  4XN1 A;  3FHE A;  3B2P A;  3FGD A;  4FYQ A;  5CU5 A;  4PVB A;  1LNA E;  7TLI A;  5HQD A;  5DYF A;  4QIR A;  4KX8 A;  2R59 A;  8TLN E;  3CHO A;  4D91 A;  1KKK A;  2GTQ A;  1THL A;  1LNF E;  4N5P E;  3FUL A;  3CHR A;  4TLI A;  6TLI A;  4MKT A;  1KR6 A;  4X2U A;  4FCA A;  4KXA A;  3CIA A;  4XN8 A;  3DNZ A;  3EBH A;  4L2L A;  3P7Q E;  3T8V A;  4Q4E A;  4TMN E;  5L41 E;  3B3B A;  4RVB A;  1FJW A;  5JT9 E;  5L8P E;  4OI5 E;  2TMN E;  4XN7 A;  4K5O A;  4P8Q A;  3N21 A;  5JVI E;  1QF0 A;  4QPE A;  3Q43 A;  3FLF A;  3F2P A;  3FTS A;  4XN2 A;  4HOM A;  1KJP A;  4GAA A;  3FU0 A;  4XNA A;  4N4E E;  3MSF A;  4QUO A;  3EBI A;  3NQZ B;  4XNB A;  3QH1 A;  4FKE A;  3FUI A;  2ZXG A;  4NZ8 A;  4IHQ A;  1QF1 A;  2DQM A;  1Z5H A;  2XPZ A;  3FUE A;  3NN7 A;  3SE6 A;  3T87 A;  3B2X A;  3T8H A;  4M65 A;  1FJ3 A;  5JS3 E;  4ZX6 A;  4FYT A;  1LNB E;  2HPO A;  1QF2 A;  4ZW7 A;  1LML A;  4K5P A;  3B7U X;  5DPE E;  4FGM A;  6TMN E;  3NQY B;  4XMU A;  1TLI A;  1KRO A;  2VJ8 A;  3CHS A;  3B7R L;  5A3Y A;  3FUH A;  2HPT A;  3DBK A;  3Q44 A;  4QHP A;  3FH8 A;  4MS6 A;  3FB0 A;  3P7T E;  4II7 A;  3FXP A;  1TRL A;  4K5M A;  3FBO A;  2XQ0 A;  5DLL A;  3FTX A;  7TLN A;  1ESP A;  3EBG A;  4D9W A;  3QH5 A;  3FTZ A;  5FSP A;  2VQX A;  4XN5 A;  4ZX3 A;  2XPY A;  3T8F A;  4K5L A;  1FJQ A;  1EZM A;  4XMZ A;  5LHD A;  3PUU A;  4XN4 A;  4K90 A;  3T8G A;  1HYT A;  3T2I E;  4AR9 A;  5TLI A;  4FKH A;  3T74 A;  3FUN A;  3T8C A;  4AR1 A;  4XO3 A;  1LNC E;  1BQB A;  3KED A;  3MDJ A;  5LDS A;  3QJX A;  4FKK A;  2TLX A;  4ZW6 A;  5DLH A;  4XMX A;  4XO4 A;  5AB2 A;  1U4G A;  3B7S A;  3FCQ A;  4RSY A;  1FJU A;  5JXN E;  5AB0 A;  3LS7 A;  3DO0 A;  5LG6 A;  5BPP A;  1TMN E;  3NQX A;  1FJT A;  4PJ6 A;  3MSN A;  1OS0 A;  4R5V A;  4OU3 A;  4KX7 A;  4E36 A;  1TLX A;  4NAQ A;  4MTW E;  3F28 A;  4XO5 A;  3T73 A;  1PE7 A;  1GXW A;  4ZQT A;  4Z7I A;  1FJO A;  4KX9 A;  5FSS A;  4TNL A;  4OW3 A;  3P7R E;  4GER A;  3FU3 A;  5AEN A;  4K89 A;  4ZW3 A;  5JSS E;  4XND A;  3B37 A;  5DPF E;  3FOR A;  3TLI A;  1L3F E;  3CHQ A;  3FUD A;  3FVP A;  1KJO A;  1Z9G E;  4XMV A;  4ARF A;  2YD0 A;  5FWQ A;  1KS7 A;  5FSJ A;  4KXB A;  1LND E;  5J6S A;  3T2H E;  4AR8 A;  3P7S E;  3FTV A;  3P7P E;  4J3B A;  3ZI6 A;  4FYR A;  4TLN A;  2G4Z A;  3QGO A;  4F5C A;  3CHP A;  4ZW5 A;  3Q7J A;  4ZW8 A;  1GW6 A;  3FTU A;  4R5T A;  4N66 E;  8TLI A;  3B34 A;  1NPC A;  4K5N A;  3FUK A;  5EV7 A;  4H57 A;  4JBS A;  3P7W E;  1KEI A;  1Y3G E;  1KTO A;  3B7T A;  1TLP E;  4Q4I A;  3P7V E;  5LIF E;  3DO2 A;  4ZX5 A;  4MZN E;  3T2J E;  3DO1 A;  3FXS A;  4PW4 A;  5K1V A;  5LWD E;  4XN9 A;  1SQM A;  5K7T A;  2WHZ A;  3FU5 A;  4MXJ E;  4MWP E;  1HS6 A;  4ZX4 A;  4XMT A;  4QME A;  5TMN E;  1ZDP E;  2TLI A;  3MSA A;  3EIM A; 
#chains in the Genus database with same CATH homology
 3SSB A;  3EBG A;  5FXN A;  3FH7 A;  3FUM A;  4OW3 A;  5DLL A;  3TMN E;  3P7R E;  3QH5 A;  4GER A;  4OI5 E;  3FU3 A;  2TMN E;  5AEN A;  4XN7 A;  3FTZ A;  4K5O A;  5FSP A;  4K89 A;  4ZW3 A;  4R5X A;  3N21 A;  3T2H E;  5JSS E;  4XND A;  3FUF A;  3U9W A;  2VQX A;  5JVI E;  4XN5 A;  1QF0 A;  4ZX3 A;  4DPR A;  4QPE A;  3T8D A;  2XPY A;  3FTY A;  1H19 A;  3B37 A;  5DPF E;  5TLN A;  3T8F A;  3FOR A;  3TLI A;  3Q43 A;  4K5L A;  1L3F E;  3P7U E;  5L3U E;  3CHQ A;  1FJQ A;  3FLF A;  3F2P A;  3FH5 A;  3FTW A;  4R7L A;  3FTS A;  3FUD A;  4XN2 A;  1EZM A;  3FVP A;  1KJO A;  1Z9G E;  4XMV A;  4D9W A;  2DQ6 A;  1KJP A;  4B52 A;  4GAA A;  1KS7 A;  5FWQ A;  5FSJ A;  3FU0 A;  3FUJ A;  3FU6 A;  4XNA A;  3MS3 A;  1LND E;  1KL6 A;  4N4E E;  3MSF A;  4XMZ A;  3FV4 A;  1LNE E;  3P7S E;  3FTV A;  3EBI A;  3P7P E;  3NQZ B;  3PUU A;  2A7G E;  4QUO A;  4XN4 A;  4XMW A;  1PE5 A;  4XNB A;  4J3B A;  4K90 A;  3QH1 A;  1FJV A;  3T8G A;  3ZI6 A;  1HYT A;  2WI0 A;  4TLN A;  4PU2 A;  3T2I E;  3FUI A;  1PE8 A;  2G4Z A;  3QGO A;  4XN1 A;  3FHE A;  2ZXG A;  3B2P A;  1QF1 A;  2DQM A;  3FGD A;  3CHP A;  2XPZ A;  3FUE A;  4PVB A;  5TLI A;  4ZW5 A;  1LNA E;  3NN7 A;  4ZW8 A;  3T87 A;  7TLI A;  5HQD A;  1GW6 A;  5DYF A;  3T74 A;  3FTU A;  3FUN A;  4R5T A;  4N66 E;  3T8C A;  8TLI A;  3B34 A;  3B2X A;  3T8H A;  4M65 A;  4QIR A;  1FJ3 A;  2R59 A;  1NPC A;  5JS3 E;  4ZX6 A;  8TLN E;  3CHO A;  4XO3 A;  4K5N A;  1LNC E;  4D91 A;  1BQB A;  7TLN A;  1LNB E;  3FUK A;  3KED A;  2HPO A;  1QF2 A;  1KKK A;  4ZW7 A;  2GTQ A;  4K5P A;  1LML A;  3QJX A;  2TLX A;  4ZW6 A;  4H57 A;  1THL A;  5DLH A;  3B7U X;  4XMX A;  1LNF E;  4XO4 A;  3P7W E;  5DPE E;  4N5P E;  6TMN E;  1U4G A;  3B7S A;  3FCQ A;  3NQY B;  1KEI A;  4RSY A;  1FJU A;  5JXN E;  3LS7 A;  3DO0 A;  1Y3G E;  3FUL A;  3CHR A;  5BPP A;  1TMN E;  4XMU A;  4TLI A;  3NQX A;  1FJT A;  1TLI A;  1KRO A;  6TLI A;  1KTO A;  3B7T A;  1TLP E;  4MKT A;  4Q4I A;  3P7V E;  2VJ8 A;  3CHS A;  5LIF E;  3B7R L;  3DO2 A;  4ZX5 A;  5A3Y A;  3MSN A;  4MZN E;  1KR6 A;  5FSS A;  3T2J E;  3DO1 A;  1OS0 A;  4R5V A;  3FXS A;  4PW4 A;  5LWD E;  4XN9 A;  3FUH A;  4X2U A;  2HPT A;  3EIM A;  3DBK A;  5L8P E;  1SQM A;  1TLX A;  5K7T A;  3Q44 A;  4QHP A;  4MTW E;  2WHZ A;  3FU5 A;  4MXJ E;  3F28 A;  4XO5 A;  3FH8 A;  3T73 A;  3CIA A;  4XN8 A;  1PE7 A;  4MWP E;  1GXW A;  3DNZ A;  1HS6 A;  4MS6 A;  4ZX4 A;  3FB0 A;  3EBH A;  4L2L A;  4XMT A;  3P7T E;  3P7Q E;  3T8V A;  4ZQT A;  1FJO A;  4Q4E A;  4QME A;  3FXP A;  1TRL A;  4K5M A;  3FBO A;  4TMN E;  5TMN E;  5L41 E;  3B3B A;  1ZDP E;  2TLI A;  4RVB A;  1FJW A;  5JT9 E;  3MSA A;  2XQ0 A;  3FTX A;  4TNL A;  1ESP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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