1LMLA

Leishmanolysin
Total Genus 135
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
475
structure length
465
Chain Sequence
VVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGVSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKASYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63).
pubmed doi rcsb
molecule tags Leishmanolysin
molecule keywords LEISHMANOLYSIN
total genus 135
structure length 465
sequence length 475
ec nomenclature ec 3.4.24.36: Leishmanolysin.
pdb deposition date 1997-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.55.10 Mainly Beta Ribbon Leishmanolysin; domain 3 Leishmanolysin domain 3 1lmlA03
2.30.34.10 Mainly Beta Roll Leishmanolysin; domain 4 Leishmanolysin domain 4 1lmlA04
3.10.170.20 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 1lmlA01
3.90.132.10 Alpha Beta Alpha-Beta Complex Leishmanolysin; domain 2 Leishmanolysin , domain 2 1lmlA02
1LMLA
chains in the Genus database with same CATH superfamily
2TMNE 6TMNE 5TLIA 5L8PE 3P7QE 1BQBA 3P7VE 5FXNA 4H57A 3FB0A 1PE8A 3FVPA 3FCQA 5A3YA 5TMNE 3DNZA 3QH5A 1PE5A 3TMNE 4B52A 1GXWA 1KTOA 3FBOA 4N5PE 2TLXA 3T8CA 3MS3A 3NQYB 3SSBA 3FXSA 3LS7A 6TLIA 1HYTA 4MWPE 1ZDPE 5FSPA 1TLPE 4N66E 3P7TE 4TLNA 1LNDE 5LIFE 3FXPA 8TLIA 3ZI6A 4M65A 2A7GE 1NPCA 5L3UE 1TMNE 1Y3GE 3DO0A 3FLFA 5JS3E 4K89A 3T8FA 3FV4A 1FJUA 3P7UE 1LMLA 3T2IE 3FGDA 4D9WA 3T87A 7TLIA 5L41E 1KJPA 5LWDE 1THLA 3NN7A 2G4ZA 1QF0A 2VQXA 3N21A 1TLIA 1LNFE 5DLHA 3DBKA 5K7TA 3P7RE 5JSSE 3FORA 1QF2A 4TMNE 1EZMA 1KEIA 3P7SE 4OW3A 3T74A 1PE7A 5DPFE 4TNLA 3TLIA 3F28A 5FSSA 1KL6A 3MSFA 1OS0A 5JVIE 3T73A 3QGOA 2WI0A 3P7WE 4K90A 3T8HA 5DPEE 1KS7A 4TLIA 3MSAA 3MSNA 4MXJE 1FJVA 2TLIA 1QF1A 3T8DA 5JXNE 1ESPA 1FJ3A 1LNCE 1KJOA 1LNEE 2WHZA 8TLNE 1LNAE 1FJWA 5JT9E 4GERA 1KKKA 3NQZB 7TLNA 1KR6A 1LNBE 1U4GA 1FJOA 4OI5E 1Z9GE 3EIMA 1FJTA 3DO2A 3NQXA 5HQDA 1L3FE 3F2PA 3QH1A 3DO1A 4N4EE 5TLNA 4MTWE 1TLXA 3T2HE 5FSJA 4D91A 1KROA 3P7PE 4MZNE 1FJQA 3T2JE 3T8GA
chains in the Genus database with same CATH topology
2TMNE 6TMNE 5TLIA 5L8PE 3P7QE 1BQBA 3P7VE 5FXNA 4H57A 3FB0A 1PE8A 3FVPA 3FCQA 5A3YA 5TMNE 3DNZA 3QH5A 1PE5A 3TMNE 4B52A 1GXWA 1KTOA 3FBOA 4N5PE 2TLXA 3T8CA 3MS3A 3NQYB 3SSBA 3FXSA 3LS7A 6TLIA 1HYTA 4MWPE 1ZDPE 5FSPA 1TLPE 4N66E 3P7TE 4TLNA 1LNDE 5LIFE 3FXPA 8TLIA 3ZI6A 4M65A 2A7GE 1NPCA 5L3UE 1TMNE 1Y3GE 3DO0A 3FLFA 5JS3E 4K89A 3T8FA 3FV4A 1FJUA 3P7UE 1LMLA 3T2IE 3FGDA 4D9WA 3T87A 7TLIA 5L41E 1KJPA 5LWDE 1THLA 3NN7A 2G4ZA 1QF0A 2VQXA 3N21A 1TLIA 1LNFE 5DLHA 3DBKA 5K7TA 3P7RE 5JSSE 3FORA 1QF2A 4TMNE 1EZMA 1KEIA 3P7SE 4OW3A 3T74A 1PE7A 5DPFE 4TNLA 3TLIA 3F28A 5FSSA 1KL6A 3MSFA 1OS0A 5JVIE 3T73A 3QGOA 2WI0A 3P7WE 4K90A 3T8HA 5DPEE 1KS7A 4TLIA 3MSAA 3MSNA 4MXJE 1FJVA 2TLIA 1QF1A 3T8DA 5JXNE 1ESPA 1FJ3A 1LNCE 1KJOA 1LNEE 2WHZA 8TLNE 1LNAE 1FJWA 5JT9E 4GERA 1KKKA 3NQZB 7TLNA 1KR6A 1LNBE 1U4GA 1FJOA 4OI5E 1Z9GE 3EIMA 1FJTA 3DO2A 3NQXA 5HQDA 1L3FE 3F2PA 3QH1A 3DO1A 4N4EE 5TLNA 4MTWE 1TLXA 3T2HE 5FSJA 4D91A 1KROA 3P7PE 4MZNE 1FJQA 3T2JE 3T8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LML A; 
#chains in the Genus database with same CATH topology
 2TMN E;  6TMN E;  5TLI A;  5L8P E;  3P7Q E;  1BQB A;  3P7V E;  5FXN A;  4H57 A;  3FB0 A;  1PE8 A;  3FVP A;  3FCQ A;  5A3Y A;  5TMN E;  3DNZ A;  3QH5 A;  1PE5 A;  3TMN E;  4B52 A;  1GXW A;  1KTO A;  3FBO A;  4N5P E;  2TLX A;  3T8C A;  3MS3 A;  3NQY B;  3SSB A;  3FXS A;  3LS7 A;  6TLI A;  1HYT A;  4MWP E;  1ZDP E;  5FSP A;  1TLP E;  4N66 E;  3P7T E;  4TLN A;  1LND E;  5LIF E;  3FXP A;  8TLI A;  3ZI6 A;  4M65 A;  2A7G E;  1NPC A;  5L3U E;  1TMN E;  1Y3G E;  3DO0 A;  3FLF A;  5JS3 E;  4K89 A;  3T8F A;  3FV4 A;  1FJU A;  3P7U E;  1LML A;  3T2I E;  3FGD A;  4D9W A;  3T87 A;  7TLI A;  5L41 E;  1KJP A;  5LWD E;  1THL A;  3NN7 A;  2G4Z A;  1QF0 A;  2VQX A;  3N21 A;  1TLI A;  1LNF E;  5DLH A;  3DBK A;  5K7T A;  3P7R E;  5JSS E;  3FOR A;  1QF2 A;  4TMN E;  1EZM A;  1KEI A;  3P7S E;  4OW3 A;  3T74 A;  1PE7 A;  5DPF E;  4TNL A;  3TLI A;  3F28 A;  5FSS A;  1KL6 A;  3MSF A;  1OS0 A;  5JVI E;  3T73 A;  3QGO A;  2WI0 A;  3P7W E;  4K90 A;  3T8H A;  5DPE E;  1KS7 A;  4TLI A;  3MSA A;  3MSN A;  4MXJ E;  1FJV A;  2TLI A;  1QF1 A;  3T8D A;  5JXN E;  1ESP A;  1FJ3 A;  1LNC E;  1KJO A;  1LNE E;  2WHZ A;  8TLN E;  1LNA E;  1FJW A;  5JT9 E;  4GER A;  1KKK A;  3NQZ B;  7TLN A;  1KR6 A;  1LNB E;  1U4G A;  1FJO A;  4OI5 E;  1Z9G E;  3EIM A;  1FJT A;  3DO2 A;  3NQX A;  5HQD A;  1L3F E;  3F2P A;  3QH1 A;  3DO1 A;  4N4E E;  5TLN A;  4MTW E;  1TLX A;  3T2H E;  5FSJ A;  4D91 A;  1KRO A;  3P7P E;  4MZN E;  1FJQ A;  3T2J E;  3T8G A; 
#chains in the Genus database with same CATH homology
 2TMN E;  6TMN E;  5TLI A;  5L8P E;  3P7Q E;  1BQB A;  3P7V E;  5FXN A;  4H57 A;  3FB0 A;  1PE8 A;  3FVP A;  3FCQ A;  5A3Y A;  5TMN E;  3DNZ A;  3QH5 A;  1PE5 A;  3TMN E;  4B52 A;  1GXW A;  1KTO A;  3FBO A;  4N5P E;  2TLX A;  3T8C A;  3MS3 A;  3NQY B;  3SSB A;  3FXS A;  3LS7 A;  6TLI A;  1HYT A;  4MWP E;  1ZDP E;  5FSP A;  1TLP E;  4N66 E;  3P7T E;  4TLN A;  1LND E;  5LIF E;  3FXP A;  8TLI A;  3ZI6 A;  4M65 A;  2A7G E;  1NPC A;  5L3U E;  1TMN E;  1Y3G E;  3DO0 A;  3FLF A;  5JS3 E;  4K89 A;  3T8F A;  3FV4 A;  1FJU A;  3P7U E;  1LML A;  3T2I E;  3FGD A;  4D9W A;  3T87 A;  7TLI A;  5L41 E;  1KJP A;  5LWD E;  1THL A;  3NN7 A;  2G4Z A;  1QF0 A;  2VQX A;  3N21 A;  1TLI A;  1LNF E;  5DLH A;  3DBK A;  5K7T A;  3P7R E;  5JSS E;  3FOR A;  1QF2 A;  4TMN E;  1EZM A;  1KEI A;  3P7S E;  4OW3 A;  3T74 A;  1PE7 A;  5DPF E;  4TNL A;  3TLI A;  3F28 A;  5FSS A;  1KL6 A;  3MSF A;  1OS0 A;  5JVI E;  3T73 A;  3QGO A;  2WI0 A;  3P7W E;  4K90 A;  3T8H A;  5DPE E;  1KS7 A;  4TLI A;  3MSA A;  3MSN A;  4MXJ E;  1FJV A;  2TLI A;  1QF1 A;  3T8D A;  5JXN E;  1ESP A;  1FJ3 A;  1LNC E;  1KJO A;  1LNE E;  2WHZ A;  8TLN E;  1LNA E;  1FJW A;  5JT9 E;  4GER A;  1KKK A;  3NQZ B;  7TLN A;  1KR6 A;  1LNB E;  1U4G A;  1FJO A;  4OI5 E;  1Z9G E;  3EIM A;  1FJT A;  3DO2 A;  3NQX A;  5HQD A;  1L3F E;  3F2P A;  3QH1 A;  3DO1 A;  4N4E E;  5TLN A;  4MTW E;  1TLX A;  3T2H E;  5FSJ A;  4D91 A;  1KRO A;  3P7P E;  4MZN E;  1FJQ A;  3T2J E;  3T8G A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...