3MSNA

Crystal structure of thermolysin in complex with n-methylurea
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Thermolysin
publication title Experimental and computational active site mapping as a starting point to fragment-based lead discovery.
pubmed doi rcsb
molecule tags Hydrolase
total genus 115
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 2010-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
A PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 3msnA02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 3msnA01
2TMNE 4N4EE 1TLPE 4MXJE 4ZW3A 3FVPA 5JSSE 4D9WA 3CHSA 4QMEA 4K5PA 3DO0A 1GXWA 1Y3GE 2GTQA 2VJ8A 3FTWA 3B7UX 3FTZA 4GAAA 1QF0A 5FWQA 5JXNE 1KKKA 3EIMA 1FJ3A 3QJXA 1THLA 4XN9A 7TLIA 2DQMA 3F2PA 3NQXA 4L2LA 5DLHA 3B7RL 1KJOA 4XN7A 3T73A 7TLNA 5L3UE 1QF2A 4PW4A 4TLIA 5HQDA 3FXPA 3FTXA 3U9WA 3B2XA 3P7VE 4K5LA 2WI0A 3DO2A 3FBOA 1LNCE 4MS6A 3FGDA 1FJQA 4XMWA 4MTWE 3EBGA 3P7WE 4XO5A 4XN1A 4ZW8A 4RVBA 3TLIA 1HS6A 4XN2A 3T8GA 3T8HA 4OW3A 3T8FA 3FUJA 3FUFA 1Z9GE 1BQBA 4ZW7A 5L41E 4XN8A 3CHPA 2ZXGA 3FTVA 3EBIA 1PE5A 4ZX3A 3DBKA 1KJPA 3MSAA 4K89A 3T2HE 2XPZA 3B2PA 3F28A 1KR6A 2TLIA 3LS7A 3DO1A 3B7TA 3P7PE 6TLIA 1TLXA 3CIAA 3FUKA 3FH5A 3NQZB 1U4GA 3T8DA 5L8PE 4QPEA 3FTUA 1H19A 5JS3E 3T87A 3MSNA 4K5NA 6TMNE 3FUDA 3FU0A 1FJVA 4OI5E 3MS3A 4TMNE 4ZX6A 4R5VA 3CHQA 4DPRA 3N21A 4PU2A 4J3BA 1FJOA 5FSPA 5TLIA 5K7TA 3FV4A 4ZW5A 4XMUA 5JVIE 4K90A 1KS7A 3B34A 4MKTA 3T2JE 5FSJA 3P7QE 4XMXA 2HPTA 4XN4A 3FH8A 4TNLA 1SQMA 3CHRA 1TLIA 3DNZA 3FXSA 3Q43A 8TLIA 1FJWA 4Q4EA 1FJUA 1ESPA 3KEDA 3FUHA 5DLLA 5FXNA 1LNFE 2VQXA 3FULA 2HPOA 3T2IE 4D91A 4XNDA 1LNDE 3T8VA 4ZX4A 4RSYA 1KL6A 5FSSA 3CHOA 4QIRA 1ZDPE 1GW6A 3QGOA 4R7LA 3Q44A 3ZI6A 8TLNE 4QHPA 3B3BA 3FU6A 3FUEA 1FJTA 3FUMA 3T74A 1L3FE 3P7SE 3NQYB 4MWPE 5TLNA 2TLXA 4X2UA 5TMNE 3FB0A 4XNBA 4ZQTA 3FORA 4B52A 3MSFA 5LWDE 3EBHA 3P7TE 4GERA 2XPYA 3P7RE 5DPFE 2XQ0A 4TLNA 3NN7A 1KEIA 4N66E 1QF1A 1EZMA 1NPCA 4M65A 1PE7A 4ZW6A 3FTSA 1TRLA 3FUIA 3QH5A 3P7UE 1HYTA 3FTYA 4K5MA 5LIFE 4R5TA 4ZX5A 4MZNE 1TMNE 3FHEA 3QH1A 4R5XA 3T8CA 3B7SA 3PUUA 4XO3A 2WHZA 2R59A 1LNAE 3FH7A 3FCQA 3TMNE 1PE8A 3FU5A 3SSBA 4K5OA 1OS0A 1LNBE 4H57A 3B37A 5DYFA 4XN5A 5BPPA 5AENA 2G4ZA 4PVBA 2DQ6A 4N5PE 2A7GE 1KTOA 4QUOA 3FLFA 3FU3A 4XNAA 5DPEE 5A3YA 4XMTA 5JT9E 1KROA 4XMZA 4XMVA 3FUNA 1LNEE 4Q4IA 4XO4A
chains in the Genus database with same CATH superfamily
5JSSE 4FKHA 1GXWA 2VJ8A 3FTWA 4FYSA 3EIMA 7TLIA 2DQMA 5J6SA 3B7RL 3B2XA 3P7VE 1FJQA 4XO5A 4MTWE 4ZW8A 4RVBA 4AR9A 3T8GA 3T8FA 5L41E 1Z9GE 4ZW7A 3CHPA 3FTVA 5LG6A 3EBIA 1PE5A 3MSAA 3B2PA 3B7TA 3FU0A 4OI5E 4TMNE 3CHQA 4PU2A 4KXBA 5FSPA 2HPTA 3FH8A 3CHRA 3FXSA 4FYTA 3KEDA 3FUHA 4KXCA 5FXNA 4XNDA 4RSYA 4FKEA 1KL6A 5K1VA 3CHOA 1ZDPE 3QGOA 8TLNE 5LDSA 1FJTA 3P7SE 2TLXA 4ZQTA 4B52A 4KX8A 3P7TE 2XPYA 3NN7A 1KEIA 1EZMA 4ZW6A 3QH5A 3P7UE 5LIFE 3T8CA 3PUUA 3FCQA 3TMNE 4K5OA 4WZ9A 5BPPA 4QUOA 3FLFA 3FU3A 5A3YA 4XO4A 4N4EE 4ZW3A 4MXJE 3FVPA 1Z1WA 4K5PA 1Y3GE 2GTQA 4GAAA 3FTZA 3B7UX 1Z5HA 5JXNE 3QJXA 1FJ3A 4XN7A 3T73A 5HQDA 3U9WA 3FBOA 3FGDA 4XMWA 3P7WE 4Z7IA 1HS6A 3T8HA 1KJPA 1KR6A 3CIAA 5L8PE 3FH5A 3Q7JA 4QPEA 6TMNE 4ZX6A 4FYRA 5K7TA 4NZ8A 4IHQA 3B34A 5FSJA 4XMXA 4XN4A 5AB0A 4TNLA 1TLIA 3Q43A 4Q4EA 1FJUA 4P8QA 5DLLA 6TLIA 2HPOA 1LNDE 3T8VA 4ARFA 4KXDA 4QIRA 3QNFA 3Q44A 4QHPA 3FUMA 3T74A 1L3FE 5TMNE 4XNBA 3FORA 4FCAA 5LWDE 5DPFE 4TLNA 1QF1A 1PE7A 3FTYA 4K5MA 4MZNE 3QH1A 2R59A 1LNAE 3B37A 4XN5A 2G4ZA 4N5PE 4XNAA 1KTOA 4XMTA 1KROA 4XMZA 1LNEE 2TMNE 4D9WA 3CHSA 3DO0A 5FWQA 1QF0A 1LMLA 1THLA 3F2PA 3NQXA 5DLHA 5L3UE 7TLNA 4PW4A 4TLIA 3FXPA 4K5LA 2WI0A 3DO2A 4XN1A 3TLIA 3SE6A 3DBKA 4K89A 2XPZA 3F28A 4KX7A 3LS7A 5C97A 3P7PE 1TLXA 3NQZB 1U4GA 3T8DA 3FTUA 4HOMA 3T87A 4K5NA 4OU3A 4DPRA 1FJOA 4ZW5A 4XMUA 5JVIE 1SQMA 3DNZA 8TLIA 4D91A 1LNFE 3FULA 3T2IE 1GW6A 3B3BA 3FUEA 5EV7A 3NQYB 5TLNA 4X2UA 3FB0A 4FKKA 3EBHA 4GERA 4M65A 4FGMA 3FTSA 3FUIA 5AB2A 3FHEA 4R5XA 3B7SA 4E36A 3FU5A 4H57A 5DYFA 4PVBA 4KXAA 5JT9E 3FUNA 1TLPE 4QMEA 4F5CA 1KKKA 4PJ6A 4XN9A 4L2LA 1KJOA 1QF2A 2YD0A 3FTXA 1LNCE 4MS6A 3EBGA 4FYQA 4XN2A 4OW3A 3FUJA 3FUFA 1BQBA 4AR8A 4XN8A 2ZXGA 5CU5A 4ZX3A 3T2HE 2TLIA 3DO1A 3FUKA 1H19A 5JS3E 3MSNA 3FUDA 1FJVA 3MS3A 4R5VA 3N21A 4J3BA 5TLIA 3FV4A 4K90A 1KS7A 4MKTA 3T2JE 3P7QE 1FJWA 1ESPA 2VQXA 4ZX4A 5FSSA 4R7LA 3ZI6A 3FU6A 4II7A 4MWPE 4AR1A 4NAQA 3MSFA 3P7RE 2XQ0A 3MDJA 4N66E 1NPCA 1TRLA 1HYTA 4R5TA 4ZX5A 1TMNE 4JBSA 4XO3A 2WHZA 3FH7A 1PE8A 3SSBA 1OS0A 1LNBE 5AENA 5LHDA 2DQ6A 2A7GE 5DPEE 4XMVA 4KX9A 4Q4IA
chains in the Genus database with same CATH topology
2TMNE 4N4EE 1TLPE 4MXJE 4ZW3A 3FVPA 5JSSE 4D9WA 3CHSA 4QMEA 4K5PA 3DO0A 1GXWA 1Y3GE 2GTQA 2VJ8A 3FTWA 3B7UX 3FTZA 4GAAA 1QF0A 5FWQA 5JXNE 1LMLA 1KKKA 3EIMA 1FJ3A 3QJXA 1THLA 4XN9A 7TLIA 2DQMA 3F2PA 3NQXA 4L2LA 5DLHA 3B7RL 1KJOA 4XN7A 3T73A 7TLNA 5L3UE 1QF2A 4PW4A 4TLIA 5HQDA 3FXPA 3FTXA 3U9WA 3B2XA 3P7VE 4K5LA 2WI0A 3DO2A 3FBOA 1LNCE 4MS6A 3FGDA 1FJQA 4XMWA 4MTWE 3EBGA 3P7WE 4XO5A 4XN1A 4ZW8A 4RVBA 3TLIA 1HS6A 4XN2A 3T8GA 3T8HA 4OW3A 3T8FA 3FUJA 3FUFA 1Z9GE 1BQBA 4ZW7A 5L41E 4XN8A 3CHPA 2ZXGA 3FTVA 3EBIA 1PE5A 4ZX3A 3DBKA 1KJPA 3MSAA 4K89A 3T2HE 2XPZA 3B2PA 3F28A 1KR6A 2TLIA 3LS7A 3DO1A 3B7TA 3P7PE 6TLIA 1TLXA 3CIAA 3FUKA 3FH5A 3NQZB 1U4GA 3T8DA 5L8PE 4QPEA 3FTUA 1H19A 5JS3E 3T87A 3MSNA 4K5NA 6TMNE 3FUDA 3FU0A 1FJVA 4OI5E 3MS3A 4TMNE 4ZX6A 4R5VA 3CHQA 4DPRA 3N21A 4PU2A 4J3BA 1FJOA 5FSPA 5TLIA 5K7TA 3FV4A 4ZW5A 4XMUA 5JVIE 4K90A 1KS7A 3B34A 4MKTA 3T2JE 5FSJA 3P7QE 4XMXA 2HPTA 4XN4A 3FH8A 4TNLA 1SQMA 3CHRA 1TLIA 3DNZA 3FXSA 3Q43A 8TLIA 1FJWA 4Q4EA 1FJUA 1ESPA 3KEDA 3FUHA 5DLLA 5FXNA 1LNFE 2VQXA 3FULA 2HPOA 3T2IE 4D91A 4XNDA 1LNDE 3T8VA 4ZX4A 4RSYA 1KL6A 5FSSA 3CHOA 4QIRA 1ZDPE 1GW6A 3QGOA 4R7LA 3Q44A 3ZI6A 8TLNE 4QHPA 3B3BA 3FU6A 3FUEA 1FJTA 3FUMA 3T74A 1L3FE 3P7SE 3NQYB 4MWPE 5TLNA 2TLXA 4X2UA 5TMNE 3FB0A 4XNBA 4ZQTA 3FORA 4B52A 3MSFA 5LWDE 3EBHA 3P7TE 4GERA 2XPYA 3P7RE 5DPFE 2XQ0A 4TLNA 3NN7A 1KEIA 4N66E 1QF1A 1EZMA 1NPCA 4M65A 1PE7A 4ZW6A 3FTSA 1TRLA 3FUIA 3QH5A 3P7UE 1HYTA 3FTYA 4K5MA 5LIFE 4R5TA 4ZX5A 4MZNE 1TMNE 3FHEA 3QH1A 4R5XA 3T8CA 3B7SA 3PUUA 4XO3A 2WHZA 2R59A 1LNAE 3FH7A 3FCQA 3TMNE 1PE8A 3FU5A 3SSBA 4K5OA 1OS0A 1LNBE 4H57A 3B37A 5DYFA 4XN5A 5BPPA 5AENA 2G4ZA 4PVBA 2DQ6A 4N5PE 2A7GE 1KTOA 4QUOA 3FLFA 3FU3A 4XNAA 5DPEE 5A3YA 4XMTA 5JT9E 1KROA 4XMZA 4XMVA 3FUNA 1LNEE 4Q4IA 4XO4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2TMN E;  4N4E E;  1TLP E;  4MXJ E;  4ZW3 A;  3FVP A;  5JSS E;  4D9W A;  3CHS A;  4QME A;  4K5P A;  3DO0 A;  1GXW A;  1Y3G E;  2GTQ A;  2VJ8 A;  3FTW A;  3B7U X;  3FTZ A;  4GAA A;  1QF0 A;  5FWQ A;  5JXN E;  1KKK A;  3EIM A;  1FJ3 A;  3QJX A;  1THL A;  4XN9 A;  7TLI A;  2DQM A;  3F2P A;  3NQX A;  4L2L A;  5DLH A;  3B7R L;  1KJO A;  4XN7 A;  3T73 A;  7TLN A;  5L3U E;  1QF2 A;  4PW4 A;  4TLI A;  5HQD A;  3FXP A;  3FTX A;  3U9W A;  3B2X A;  3P7V E;  4K5L A;  2WI0 A;  3DO2 A;  3FBO A;  1LNC E;  4MS6 A;  3FGD A;  1FJQ A;  4XMW A;  4MTW E;  3EBG A;  3P7W E;  4XO5 A;  4XN1 A;  4ZW8 A;  4RVB A;  3TLI A;  1HS6 A;  4XN2 A;  3T8G A;  3T8H A;  4OW3 A;  3T8F A;  3FUJ A;  3FUF A;  1Z9G E;  1BQB A;  4ZW7 A;  5L41 E;  4XN8 A;  3CHP A;  2ZXG A;  3FTV A;  3EBI A;  1PE5 A;  4ZX3 A;  3DBK A;  1KJP A;  3MSA A;  4K89 A;  3T2H E;  2XPZ A;  3B2P A;  3F28 A;  1KR6 A;  2TLI A;  3LS7 A;  3DO1 A;  3B7T A;  3P7P E;  6TLI A;  1TLX A;  3CIA A;  3FUK A;  3FH5 A;  3NQZ B;  1U4G A;  3T8D A;  5L8P E;  4QPE A;  3FTU A;  1H19 A;  5JS3 E;  3T87 A;  3MSN A;  4K5N A;  6TMN E;  3FUD A;  3FU0 A;  1FJV A;  4OI5 E;  3MS3 A;  4TMN E;  4ZX6 A;  4R5V A;  3CHQ A;  4DPR A;  3N21 A;  4PU2 A;  4J3B A;  1FJO A;  5FSP A;  5TLI A;  5K7T A;  3FV4 A;  4ZW5 A;  4XMU A;  5JVI E;  4K90 A;  1KS7 A;  3B34 A;  4MKT A;  3T2J E;  5FSJ A;  3P7Q E;  4XMX A;  2HPT A;  4XN4 A;  3FH8 A;  4TNL A;  1SQM A;  3CHR A;  1TLI A;  3DNZ A;  3FXS A;  3Q43 A;  8TLI A;  1FJW A;  4Q4E A;  1FJU A;  1ESP A;  3KED A;  3FUH A;  5DLL A;  5FXN A;  1LNF E;  2VQX A;  3FUL A;  2HPO A;  3T2I E;  4D91 A;  4XND A;  1LND E;  3T8V A;  4ZX4 A;  4RSY A;  1KL6 A;  5FSS A;  3CHO A;  4QIR A;  1ZDP E;  1GW6 A;  3QGO A;  4R7L A;  3Q44 A;  3ZI6 A;  8TLN E;  4QHP A;  3B3B A;  3FU6 A;  3FUE A;  1FJT A;  3FUM A;  3T74 A;  1L3F E;  3P7S E;  3NQY B;  4MWP E;  5TLN A;  2TLX A;  4X2U A;  5TMN E;  3FB0 A;  4XNB A;  4ZQT A;  3FOR A;  4B52 A;  3MSF A;  5LWD E;  3EBH A;  3P7T E;  4GER A;  2XPY A;  3P7R E;  5DPF E;  2XQ0 A;  4TLN A;  3NN7 A;  1KEI A;  4N66 E;  1QF1 A;  1EZM A;  1NPC A;  4M65 A;  1PE7 A;  4ZW6 A;  3FTS A;  1TRL A;  3FUI A;  3QH5 A;  3P7U E;  1HYT A;  3FTY A;  4K5M A;  5LIF E;  4R5T A;  4ZX5 A;  4MZN E;  1TMN E;  3FHE A;  3QH1 A;  4R5X A;  3T8C A;  3B7S A;  3PUU A;  4XO3 A;  2WHZ A;  2R59 A;  1LNA E;  3FH7 A;  3FCQ A;  3TMN E;  1PE8 A;  3FU5 A;  3SSB A;  4K5O A;  1OS0 A;  1LNB E;  4H57 A;  3B37 A;  5DYF A;  4XN5 A;  5BPP A;  5AEN A;  2G4Z A;  4PVB A;  2DQ6 A;  4N5P E;  2A7G E;  1KTO A;  4QUO A;  3FLF A;  3FU3 A;  4XNA A;  5DPE E;  5A3Y A;  4XMT A;  5JT9 E;  1KRO A;  4XMZ A;  4XMV A;  3FUN A;  1LNE E;  4Q4I A;  4XO4 A; 
#chains in the Genus database with same CATH topology
 5JSS E;  4FKH A;  1GXW A;  2VJ8 A;  3FTW A;  4FYS A;  3EIM A;  7TLI A;  2DQM A;  5J6S A;  3B7R L;  3B2X A;  3P7V E;  1FJQ A;  4XO5 A;  4MTW E;  4ZW8 A;  4RVB A;  4AR9 A;  3T8G A;  3T8F A;  5L41 E;  1Z9G E;  4ZW7 A;  3CHP A;  3FTV A;  5LG6 A;  3EBI A;  1PE5 A;  3MSA A;  3B2P A;  3B7T A;  3FU0 A;  4OI5 E;  4TMN E;  3CHQ A;  4PU2 A;  4KXB A;  5FSP A;  2HPT A;  3FH8 A;  3CHR A;  3FXS A;  4FYT A;  3KED A;  3FUH A;  4KXC A;  5FXN A;  4XND A;  4RSY A;  4FKE A;  1KL6 A;  5K1V A;  3CHO A;  1ZDP E;  3QGO A;  8TLN E;  5LDS A;  1FJT A;  3P7S E;  2TLX A;  4ZQT A;  4B52 A;  4KX8 A;  3P7T E;  2XPY A;  3NN7 A;  1KEI A;  1EZM A;  4ZW6 A;  3QH5 A;  3P7U E;  5LIF E;  3T8C A;  3PUU A;  3FCQ A;  3TMN E;  4K5O A;  4WZ9 A;  5BPP A;  4QUO A;  3FLF A;  3FU3 A;  5A3Y A;  4XO4 A;  4N4E E;  4ZW3 A;  4MXJ E;  3FVP A;  1Z1W A;  4K5P A;  1Y3G E;  2GTQ A;  4GAA A;  3FTZ A;  3B7U X;  1Z5H A;  5JXN E;  3QJX A;  1FJ3 A;  4XN7 A;  3T73 A;  5HQD A;  3U9W A;  3FBO A;  3FGD A;  4XMW A;  3P7W E;  4Z7I A;  1HS6 A;  3T8H A;  1KJP A;  1KR6 A;  3CIA A;  5L8P E;  3FH5 A;  3Q7J A;  4QPE A;  6TMN E;  4ZX6 A;  4FYR A;  5K7T A;  4NZ8 A;  4IHQ A;  3B34 A;  5FSJ A;  4XMX A;  4XN4 A;  5AB0 A;  4TNL A;  1TLI A;  3Q43 A;  4Q4E A;  1FJU A;  4P8Q A;  5DLL A;  6TLI A;  2HPO A;  1LND E;  3T8V A;  4ARF A;  4KXD A;  4QIR A;  3QNF A;  3Q44 A;  4QHP A;  3FUM A;  3T74 A;  1L3F E;  5TMN E;  4XNB A;  3FOR A;  4FCA A;  5LWD E;  5DPF E;  4TLN A;  1QF1 A;  1PE7 A;  3FTY A;  4K5M A;  4MZN E;  3QH1 A;  2R59 A;  1LNA E;  3B37 A;  4XN5 A;  2G4Z A;  4N5P E;  4XNA A;  1KTO A;  4XMT A;  1KRO A;  4XMZ A;  1LNE E;  2TMN E;  4D9W A;  3CHS A;  3DO0 A;  5FWQ A;  1QF0 A;  1LML A;  1THL A;  3F2P A;  3NQX A;  5DLH A;  5L3U E;  7TLN A;  4PW4 A;  4TLI A;  3FXP A;  4K5L A;  2WI0 A;  3DO2 A;  4XN1 A;  3TLI A;  3SE6 A;  3DBK A;  4K89 A;  2XPZ A;  3F28 A;  4KX7 A;  3LS7 A;  5C97 A;  3P7P E;  1TLX A;  3NQZ B;  1U4G A;  3T8D A;  3FTU A;  4HOM A;  3T87 A;  4K5N A;  4OU3 A;  4DPR A;  1FJO A;  4ZW5 A;  4XMU A;  5JVI E;  1SQM A;  3DNZ A;  8TLI A;  4D91 A;  1LNF E;  3FUL A;  3T2I E;  1GW6 A;  3B3B A;  3FUE A;  5EV7 A;  3NQY B;  5TLN A;  4X2U A;  3FB0 A;  4FKK A;  3EBH A;  4GER A;  4M65 A;  4FGM A;  3FTS A;  3FUI A;  5AB2 A;  3FHE A;  4R5X A;  3B7S A;  4E36 A;  3FU5 A;  4H57 A;  5DYF A;  4PVB A;  4KXA A;  5JT9 E;  3FUN A;  1TLP E;  4QME A;  4F5C A;  1KKK A;  4PJ6 A;  4XN9 A;  4L2L A;  1KJO A;  1QF2 A;  2YD0 A;  3FTX A;  1LNC E;  4MS6 A;  3EBG A;  4FYQ A;  4XN2 A;  4OW3 A;  3FUJ A;  3FUF A;  1BQB A;  4AR8 A;  4XN8 A;  2ZXG A;  5CU5 A;  4ZX3 A;  3T2H E;  2TLI A;  3DO1 A;  3FUK A;  1H19 A;  5JS3 E;  3MSN A;  3FUD A;  1FJV A;  3MS3 A;  4R5V A;  3N21 A;  4J3B A;  5TLI A;  3FV4 A;  4K90 A;  1KS7 A;  4MKT A;  3T2J E;  3P7Q E;  1FJW A;  1ESP A;  2VQX A;  4ZX4 A;  5FSS A;  4R7L A;  3ZI6 A;  3FU6 A;  4II7 A;  4MWP E;  4AR1 A;  4NAQ A;  3MSF A;  3P7R E;  2XQ0 A;  3MDJ A;  4N66 E;  1NPC A;  1TRL A;  1HYT A;  4R5T A;  4ZX5 A;  1TMN E;  4JBS A;  4XO3 A;  2WHZ A;  3FH7 A;  1PE8 A;  3SSB A;  1OS0 A;  1LNB E;  5AEN A;  5LHD A;  2DQ6 A;  2A7G E;  5DPE E;  4XMV A;  4KX9 A;  4Q4I A; 
#chains in the Genus database with same CATH homology
 2TMN E;  4N4E E;  1TLP E;  4MXJ E;  4ZW3 A;  3FVP A;  5JSS E;  4D9W A;  3CHS A;  4QME A;  4K5P A;  3DO0 A;  1GXW A;  1Y3G E;  2GTQ A;  2VJ8 A;  3FTW A;  3B7U X;  3FTZ A;  4GAA A;  1QF0 A;  5FWQ A;  5JXN E;  1LML A;  1KKK A;  3EIM A;  1FJ3 A;  3QJX A;  1THL A;  4XN9 A;  7TLI A;  2DQM A;  3F2P A;  3NQX A;  4L2L A;  5DLH A;  3B7R L;  1KJO A;  4XN7 A;  3T73 A;  7TLN A;  5L3U E;  1QF2 A;  4PW4 A;  4TLI A;  5HQD A;  3FXP A;  3FTX A;  3U9W A;  3B2X A;  3P7V E;  4K5L A;  2WI0 A;  3DO2 A;  3FBO A;  1LNC E;  4MS6 A;  3FGD A;  1FJQ A;  4XMW A;  4MTW E;  3EBG A;  3P7W E;  4XO5 A;  4XN1 A;  4ZW8 A;  4RVB A;  3TLI A;  1HS6 A;  4XN2 A;  3T8G A;  3T8H A;  4OW3 A;  3T8F A;  3FUJ A;  3FUF A;  1Z9G E;  1BQB A;  4ZW7 A;  5L41 E;  4XN8 A;  3CHP A;  2ZXG A;  3FTV A;  3EBI A;  1PE5 A;  4ZX3 A;  3DBK A;  1KJP A;  3MSA A;  4K89 A;  3T2H E;  2XPZ A;  3B2P A;  3F28 A;  1KR6 A;  2TLI A;  3LS7 A;  3DO1 A;  3B7T A;  3P7P E;  6TLI A;  1TLX A;  3CIA A;  3FUK A;  3FH5 A;  3NQZ B;  1U4G A;  3T8D A;  5L8P E;  4QPE A;  3FTU A;  1H19 A;  5JS3 E;  3T87 A;  3MSN A;  4K5N A;  6TMN E;  3FUD A;  3FU0 A;  1FJV A;  4OI5 E;  3MS3 A;  4TMN E;  4ZX6 A;  4R5V A;  3CHQ A;  4DPR A;  3N21 A;  4PU2 A;  4J3B A;  1FJO A;  5FSP A;  5TLI A;  5K7T A;  3FV4 A;  4ZW5 A;  4XMU A;  5JVI E;  4K90 A;  1KS7 A;  3B34 A;  4MKT A;  3T2J E;  5FSJ A;  3P7Q E;  4XMX A;  2HPT A;  4XN4 A;  3FH8 A;  4TNL A;  1SQM A;  3CHR A;  1TLI A;  3DNZ A;  3FXS A;  3Q43 A;  8TLI A;  1FJW A;  4Q4E A;  1FJU A;  1ESP A;  3KED A;  3FUH A;  5DLL A;  5FXN A;  1LNF E;  2VQX A;  3FUL A;  2HPO A;  3T2I E;  4D91 A;  4XND A;  1LND E;  3T8V A;  4ZX4 A;  4RSY A;  1KL6 A;  5FSS A;  3CHO A;  4QIR A;  1ZDP E;  1GW6 A;  3QGO A;  4R7L A;  3Q44 A;  3ZI6 A;  8TLN E;  4QHP A;  3B3B A;  3FU6 A;  3FUE A;  1FJT A;  3FUM A;  3T74 A;  1L3F E;  3P7S E;  3NQY B;  4MWP E;  5TLN A;  2TLX A;  4X2U A;  5TMN E;  3FB0 A;  4XNB A;  4ZQT A;  3FOR A;  4B52 A;  3MSF A;  5LWD E;  3EBH A;  3P7T E;  4GER A;  2XPY A;  3P7R E;  5DPF E;  2XQ0 A;  4TLN A;  3NN7 A;  1KEI A;  4N66 E;  1QF1 A;  1EZM A;  1NPC A;  4M65 A;  1PE7 A;  4ZW6 A;  3FTS A;  1TRL A;  3FUI A;  3QH5 A;  3P7U E;  1HYT A;  3FTY A;  4K5M A;  5LIF E;  4R5T A;  4ZX5 A;  4MZN E;  1TMN E;  3FHE A;  3QH1 A;  4R5X A;  3T8C A;  3B7S A;  3PUU A;  4XO3 A;  2WHZ A;  2R59 A;  1LNA E;  3FH7 A;  3FCQ A;  3TMN E;  1PE8 A;  3FU5 A;  3SSB A;  4K5O A;  1OS0 A;  1LNB E;  4H57 A;  3B37 A;  5DYF A;  4XN5 A;  5BPP A;  5AEN A;  2G4Z A;  4PVB A;  2DQ6 A;  4N5P E;  2A7G E;  1KTO A;  4QUO A;  3FLF A;  3FU3 A;  4XNA A;  5DPE E;  5A3Y A;  4XMT A;  5JT9 E;  1KRO A;  4XMZ A;  4XMV A;  3FUN A;  1LNE E;  4Q4I A;  4XO4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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