3N21A

Crystal structure of thermolysin in complex with s-1,2-propandiol
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Thermolysin
publication title Experimental and computational active site mapping as a starting point to fragment-based lead discovery.
pubmed doi rcsb
molecule tags Hydrolase
total genus 118
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 2010-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
A PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 3n21A02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 3n21A01
4XN8A 3FTSA 3FH7A 4XNDA 3MS3A 3FUKA 1TLXA 4QPEA 3Q44A 4QHPA 1ZDPE 1TLIA 3FVPA 2XPZA 1KJPA 3ZI6A 2G4ZA 1THLA 3FU0A 3FU3A 1FJUA 4XN4A 3FV4A 3EBIA 5TLIA 4D9WA 5HQDA 3P7UE 3FUJA 4MTWE 4PVBA 4TMNE 4ZW7A 3PUUA 4QUOA 1H19A 4DPRA 5TLNA 2VQXA 4XMZA 3DO1A 5L41E 6TMNE 1SQMA 3QH5A 3T8VA 5BPPA 3T8GA 3P7VE 1LNFE 3T8DA 4XNAA 3TMNE 3B7RL 1NPCA 2HPOA 3FCQA 4R5XA 3FTUA 4RSYA 3NN7A 4ZX5A 1LNBE 4OI5E 4R7LA 4ZW3A 3B7UX 3CHSA 3FBOA 1GW6A 5FSJA 3MSAA 5JSSE 4ZX4A 4B52A 3DNZA 4K5LA 4MZNE 2XPYA 3FB0A 3FXPA 3FTZA 4XMVA 1U4GA 4K5OA 1KEIA 3N21A 1BQBA 2R59A 3T73A 4ZX3A 3FUMA 4XN1A 3FUNA 3T2JE 7TLNA 3CHQA 3SSBA 4MS6A 1KTOA 3MSNA 1FJWA 1PE5A 4TNLA 3T8HA 1EZMA 3EBGA 4M65A 5DPEE 8TLIA 4XNBA 5JT9E 3QH1A 4K89A 1HYTA 4R5TA 3FTWA 5JVIE 3DO0A 3T2IE 2VJ8A 2GTQA 3FUEA 1ESPA 3QJXA 3F28A 3P7PE 1KKKA 4K90A 4OW3A 4ZW6A 5JXNE 2DQMA 1QF2A 1LNDE 3FLFA 4TLIA 4PW4A 4XN9A 4Q4IA 4D91A 3B2XA 3P7WE 3T8FA 1FJQA 1TRLA 7TLIA 4XN5A 4GERA 4TLNA 4X2UA 1TMNE 1KL6A 3NQXA 4MXJE 3CHOA 3CIAA 3B7SA 4XN2A 2WHZA 4XO5A 5K7TA 1KROA 3DBKA 1L3FE 5LWDE 3CHPA 3FU5A 1LNEE 3F2PA 4XMUA 2HPTA 4N5PE 8TLNE 1QF1A 5JS3E 3T2HE 3B3BA 1FJ3A 4XO3A 3FTYA 3CHRA 2ZXGA 3P7QE 4R5VA 3QGOA 3MSFA 4XMWA 4MWPE 5DLHA 5DYFA 3T8CA 3FTVA 3FHEA 3FUDA 4MKTA 1FJOA 1TLPE 3LS7A 1FJVA 4K5MA 1Z9GE 4J3BA 3EIMA 1GXWA 3FUIA 3FU6A 4GAAA 3T87A 1KJOA 1Y3GE 4ZQTA 2XQ0A 3FH8A 4ZW5A 5LIFE 1FJTA 1LNAE 5FSSA 1PE8A 4N4EE 2WI0A 2A7GE 3KEDA 3P7SE 4Q4EA 1OS0A 4XN7A 4L2LA 3TLIA 4H57A 4XO4A 3EBHA 3FGDA 4RVBA 4K5PA 4ZW8A 3NQYB 3FXSA 3P7RE 5AENA 4XMXA 4QMEA 5DLLA 4ZX6A 5A3YA 3NQZB 5L8PE 3Q43A 3FORA 5DPFE 4XMTA 4QIRA 4K5NA 5FXNA 5FWQA 3FUHA 1QF0A 3B2PA 4PU2A 6TLIA 3B37A 5FSPA 4N66E 3U9WA 3FULA 3P7TE 2TLIA 3T74A 5TMNE 1HS6A 2TMNE 1LNCE 2DQ6A 2TLXA 1KS7A 5L3UE 3B34A 3DO2A 3B7TA 3FUFA 3FTXA 1PE7A 1KR6A 3FH5A
chains in the Genus database with same CATH superfamily
4XN8A 3FTSA 1TLXA 4QPEA 3Q44A 1KJPA 2G4ZA 4XN4A 4D9WA 4ZW7A 5L41E 3T8VA 5BPPA 4XNAA 5LDSA 4R5XA 4WZ9A 4KXDA 4OI5E 3CHSA 3FBOA 5JSSE 4MZNE 4XMVA 3T73A 1Z5HA 4ZX3A 3CHQA 3MSNA 1FJWA 3T8HA 4M65A 4XNBA 4K89A 4FCAA 4NAQA 1LMLA 3QJXA 1QF2A 4TLIA 1TRLA 4GERA 3T2JE 1TMNE 1KL6A 3CIAA 4XN2A 2WHZA 3DBKA 1L3FE 5LWDE 3CHPA 5JS3E 4KXCA 3B3BA 5LHDA 4FYQA 3FTYA 3P7QE 5DYFA 3FHEA 1FJOA 1TLPE 3LS7A 5LG6A 4J3BA 5K1VA 1Y3GE 4JBSA 2XQ0A 4ZQTA 1FJTA 4P8QA 5FSSA 4N4EE 2WI0A 4H57A 4RVBA 4QMEA 3FORA 4XMTA 3B2PA 6TLIA 3U9WA 3T74A 5TMNE 1HS6A 2TLXA 3B7TA 3FUFA 3FTXA 4Z7IA 4XNDA 3ZI6A 1THLA 3FU3A 3EBIA 3FUJA 4PVBA 4TMNE 3PUUA 4QUOA 4DPRA 6TMNE 3P7VE 1LNFE 3TMNE 2HPOA 4FYSA 3FTUA 4NZ8A 3NN7A 4R7LA 4ZW3A 4E36A 3FB0A 4K5OA 1PE5A 3QH1A 1HYTA 5JVIE 3FTWA 3DO0A 3T2IE 4AR1A 3P7PE 1LNDE 4D91A 1FJQA 4TLNA 3NQXA 3B7SA 4PJ6A 2HPTA 1FJ3A 4XO3A 3QGOA 3MSFA 4MWPE 3FTVA 4MKTA 4ARFA 3FH8A 1LNAE 2A7GE 4XO4A 3EBHA 3FGDA 4K5PA 4XMXA 4ZX6A 5A3YA 5L8PE 3Q43A 5DPFE 4II7A 3B37A 4N66E 3P7TE 2TLIA 5AB2A 5L3UE 3B34A 3FH7A 4HOMA 4QHPA 4IHQA 3FVPA 3FU0A 1FJUA 3FV4A 3P7UE 4KXAA 4KX9A 3QH5A 3B7RL 3Q7JA 5CU5A 3MSAA 5C97A 3FXPA 3FTZA 1U4GA 1KEIA 3N21A 1BQBA 2R59A 4FYTA 3FUMA 3FUNA 7TLNA 4MS6A 1KTOA 1EZMA 3EBGA 4R5TA 2VJ8A 2GTQA 4K90A 4OW3A 3F28A 5JXNE 1KKKA 4ZW6A 2DQMA 3FLFA 4XN9A 4Q4IA 3B2XA 3P7WE 3T8FA 4XN5A 4X2UA 4MXJE 5K7TA 3CHOA 4FKHA 1Z1WA 3FU5A 4FKKA 4N5PE 3T2HE 3QNFA 2ZXGA 5J6SA 1Z9GE 3FUIA 1GXWA 3FU6A 5LIFE 3KEDA 4Q4EA 3P7SE 4FYRA 4XN7A 4L2LA 3TLIA 4ZW8A 4K5NA 5FXNA 1QF0A 3DO2A 1KR6A 3T8GA 3FH5A 5AB0A 3MS3A 4FKEA 3FUKA 1ZDPE 1TLIA 2XPZA 4OU3A 5TLIA 3MDJA 5HQDA 5EV7A 4MTWE 4FGMA 1H19A 5TLNA 2VQXA 4XMZA 3DO1A 1SQMA 3T8DA 1NPCA 3FCQA 4RSYA 4ZX5A 1LNBE 4AR9A 3B7UX 5FSJA 1GW6A 4ZX4A 4B52A 3DNZA 4K5LA 2XPYA 4XN1A 3SSBA 4TNLA 5DPEE 8TLIA 5JT9E 3FUEA 1ESPA 4F5CA 4PW4A 7TLIA 4AR8A 4XO5A 1KROA 1LNEE 3F2PA 4XMUA 8TLNE 1QF1A 4KX7A 3CHRA 4KXBA 4R5VA 4XMWA 3T8CA 5DLHA 3FUDA 1FJVA 2YD0A 4K5MA 3EIMA 3SE6A 4GAAA 3T87A 1KJOA 4ZW5A 1PE8A 1OS0A 3NQYB 3FXSA 3P7RE 5AENA 5DLLA 3NQZB 4QIRA 5FWQA 4KX8A 3FUHA 4PU2A 5FSPA 3FULA 2TMNE 1LNCE 2DQ6A 1KS7A 1PE7A
chains in the Genus database with same CATH topology
4XN8A 3FTSA 3FH7A 4XNDA 3MS3A 3FUKA 1TLXA 4QPEA 3Q44A 4QHPA 1ZDPE 1TLIA 3FVPA 2XPZA 1KJPA 3ZI6A 2G4ZA 1THLA 3FU0A 3FU3A 1FJUA 4XN4A 3FV4A 3EBIA 5TLIA 4D9WA 5HQDA 3P7UE 3FUJA 4MTWE 4PVBA 4TMNE 4ZW7A 3PUUA 4QUOA 1H19A 4DPRA 5TLNA 2VQXA 4XMZA 3DO1A 5L41E 6TMNE 1SQMA 3QH5A 3T8VA 5BPPA 3T8GA 3P7VE 1LNFE 3T8DA 4XNAA 3TMNE 3B7RL 1NPCA 2HPOA 3FCQA 4R5XA 3FTUA 4RSYA 3NN7A 4ZX5A 1LNBE 4OI5E 4R7LA 4ZW3A 3B7UX 3CHSA 3FBOA 1GW6A 5FSJA 3MSAA 5JSSE 4ZX4A 4B52A 3DNZA 4K5LA 4MZNE 2XPYA 3FB0A 3FXPA 3FTZA 4XMVA 1U4GA 4K5OA 1KEIA 3N21A 1BQBA 2R59A 3T73A 4ZX3A 3FUMA 4XN1A 3FUNA 3T2JE 7TLNA 3CHQA 3SSBA 4MS6A 1KTOA 3MSNA 1FJWA 1PE5A 4TNLA 3T8HA 1EZMA 3EBGA 4M65A 5DPEE 8TLIA 4XNBA 5JT9E 3QH1A 4K89A 1HYTA 4R5TA 3FTWA 5JVIE 3DO0A 3T2IE 2VJ8A 2GTQA 3FUEA 1LMLA 1ESPA 3QJXA 3F28A 3P7PE 1KKKA 4K90A 4OW3A 4ZW6A 5JXNE 2DQMA 1QF2A 1LNDE 3FLFA 4TLIA 4PW4A 4XN9A 4Q4IA 4D91A 3B2XA 3P7WE 3T8FA 1FJQA 1TRLA 7TLIA 4XN5A 4GERA 4TLNA 4X2UA 1TMNE 1KL6A 3NQXA 4MXJE 3CHOA 3CIAA 3B7SA 4XN2A 2WHZA 4XO5A 5K7TA 1KROA 3DBKA 1L3FE 5LWDE 3CHPA 3FU5A 1LNEE 3F2PA 4XMUA 2HPTA 4N5PE 8TLNE 1QF1A 5JS3E 3T2HE 3B3BA 1FJ3A 4XO3A 3FTYA 3CHRA 2ZXGA 3P7QE 4R5VA 3QGOA 3MSFA 4XMWA 4MWPE 5DLHA 5DYFA 3T8CA 3FTVA 3FHEA 3FUDA 4MKTA 1FJOA 1TLPE 3LS7A 1FJVA 4K5MA 1Z9GE 4J3BA 3EIMA 1GXWA 3FUIA 3FU6A 4GAAA 3T87A 1KJOA 1Y3GE 4ZQTA 2XQ0A 3FH8A 4ZW5A 5LIFE 1FJTA 1LNAE 5FSSA 1PE8A 4N4EE 2WI0A 2A7GE 3KEDA 3P7SE 4Q4EA 1OS0A 4XN7A 4L2LA 3TLIA 4H57A 4XO4A 3EBHA 3FGDA 4RVBA 4K5PA 4ZW8A 3NQYB 3FXSA 3P7RE 5AENA 4XMXA 4QMEA 5DLLA 4ZX6A 5A3YA 3NQZB 5L8PE 3Q43A 3FORA 5DPFE 4XMTA 4QIRA 4K5NA 5FXNA 5FWQA 3FUHA 1QF0A 3B2PA 4PU2A 6TLIA 3B37A 5FSPA 4N66E 3U9WA 3FULA 3P7TE 2TLIA 3T74A 5TMNE 1HS6A 2TMNE 1LNCE 2DQ6A 2TLXA 1KS7A 5L3UE 3B34A 3DO2A 3B7TA 3FUFA 3FTXA 1PE7A 1KR6A 3FH5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XN8 A;  3FTS A;  3FH7 A;  4XND A;  3MS3 A;  3FUK A;  1TLX A;  4QPE A;  3Q44 A;  4QHP A;  1ZDP E;  1TLI A;  3FVP A;  2XPZ A;  1KJP A;  3ZI6 A;  2G4Z A;  1THL A;  3FU0 A;  3FU3 A;  1FJU A;  4XN4 A;  3FV4 A;  3EBI A;  5TLI A;  4D9W A;  5HQD A;  3P7U E;  3FUJ A;  4MTW E;  4PVB A;  4TMN E;  4ZW7 A;  3PUU A;  4QUO A;  1H19 A;  4DPR A;  5TLN A;  2VQX A;  4XMZ A;  3DO1 A;  5L41 E;  6TMN E;  1SQM A;  3QH5 A;  3T8V A;  5BPP A;  3T8G A;  3P7V E;  1LNF E;  3T8D A;  4XNA A;  3TMN E;  3B7R L;  1NPC A;  2HPO A;  3FCQ A;  4R5X A;  3FTU A;  4RSY A;  3NN7 A;  4ZX5 A;  1LNB E;  4OI5 E;  4R7L A;  4ZW3 A;  3B7U X;  3CHS A;  3FBO A;  1GW6 A;  5FSJ A;  3MSA A;  5JSS E;  4ZX4 A;  4B52 A;  3DNZ A;  4K5L A;  4MZN E;  2XPY A;  3FB0 A;  3FXP A;  3FTZ A;  4XMV A;  1U4G A;  4K5O A;  1KEI A;  3N21 A;  1BQB A;  2R59 A;  3T73 A;  4ZX3 A;  3FUM A;  4XN1 A;  3FUN A;  3T2J E;  7TLN A;  3CHQ A;  3SSB A;  4MS6 A;  1KTO A;  3MSN A;  1FJW A;  1PE5 A;  4TNL A;  3T8H A;  1EZM A;  3EBG A;  4M65 A;  5DPE E;  8TLI A;  4XNB A;  5JT9 E;  3QH1 A;  4K89 A;  1HYT A;  4R5T A;  3FTW A;  5JVI E;  3DO0 A;  3T2I E;  2VJ8 A;  2GTQ A;  3FUE A;  1ESP A;  3QJX A;  3F28 A;  3P7P E;  1KKK A;  4K90 A;  4OW3 A;  4ZW6 A;  5JXN E;  2DQM A;  1QF2 A;  1LND E;  3FLF A;  4TLI A;  4PW4 A;  4XN9 A;  4Q4I A;  4D91 A;  3B2X A;  3P7W E;  3T8F A;  1FJQ A;  1TRL A;  7TLI A;  4XN5 A;  4GER A;  4TLN A;  4X2U A;  1TMN E;  1KL6 A;  3NQX A;  4MXJ E;  3CHO A;  3CIA A;  3B7S A;  4XN2 A;  2WHZ A;  4XO5 A;  5K7T A;  1KRO A;  3DBK A;  1L3F E;  5LWD E;  3CHP A;  3FU5 A;  1LNE E;  3F2P A;  4XMU A;  2HPT A;  4N5P E;  8TLN E;  1QF1 A;  5JS3 E;  3T2H E;  3B3B A;  1FJ3 A;  4XO3 A;  3FTY A;  3CHR A;  2ZXG A;  3P7Q E;  4R5V A;  3QGO A;  3MSF A;  4XMW A;  4MWP E;  5DLH A;  5DYF A;  3T8C A;  3FTV A;  3FHE A;  3FUD A;  4MKT A;  1FJO A;  1TLP E;  3LS7 A;  1FJV A;  4K5M A;  1Z9G E;  4J3B A;  3EIM A;  1GXW A;  3FUI A;  3FU6 A;  4GAA A;  3T87 A;  1KJO A;  1Y3G E;  4ZQT A;  2XQ0 A;  3FH8 A;  4ZW5 A;  5LIF E;  1FJT A;  1LNA E;  5FSS A;  1PE8 A;  4N4E E;  2WI0 A;  2A7G E;  3KED A;  3P7S E;  4Q4E A;  1OS0 A;  4XN7 A;  4L2L A;  3TLI A;  4H57 A;  4XO4 A;  3EBH A;  3FGD A;  4RVB A;  4K5P A;  4ZW8 A;  3NQY B;  3FXS A;  3P7R E;  5AEN A;  4XMX A;  4QME A;  5DLL A;  4ZX6 A;  5A3Y A;  3NQZ B;  5L8P E;  3Q43 A;  3FOR A;  5DPF E;  4XMT A;  4QIR A;  4K5N A;  5FXN A;  5FWQ A;  3FUH A;  1QF0 A;  3B2P A;  4PU2 A;  6TLI A;  3B37 A;  5FSP A;  4N66 E;  3U9W A;  3FUL A;  3P7T E;  2TLI A;  3T74 A;  5TMN E;  1HS6 A;  2TMN E;  1LNC E;  2DQ6 A;  2TLX A;  1KS7 A;  5L3U E;  3B34 A;  3DO2 A;  3B7T A;  3FUF A;  3FTX A;  1PE7 A;  1KR6 A;  3FH5 A; 
#chains in the Genus database with same CATH topology
 4XN8 A;  3FTS A;  1TLX A;  4QPE A;  3Q44 A;  1KJP A;  2G4Z A;  4XN4 A;  4D9W A;  4ZW7 A;  5L41 E;  3T8V A;  5BPP A;  4XNA A;  5LDS A;  4R5X A;  4WZ9 A;  4KXD A;  4OI5 E;  3CHS A;  3FBO A;  5JSS E;  4MZN E;  4XMV A;  3T73 A;  1Z5H A;  4ZX3 A;  3CHQ A;  3MSN A;  1FJW A;  3T8H A;  4M65 A;  4XNB A;  4K89 A;  4FCA A;  4NAQ A;  1LML A;  3QJX A;  1QF2 A;  4TLI A;  1TRL A;  4GER A;  3T2J E;  1TMN E;  1KL6 A;  3CIA A;  4XN2 A;  2WHZ A;  3DBK A;  1L3F E;  5LWD E;  3CHP A;  5JS3 E;  4KXC A;  3B3B A;  5LHD A;  4FYQ A;  3FTY A;  3P7Q E;  5DYF A;  3FHE A;  1FJO A;  1TLP E;  3LS7 A;  5LG6 A;  4J3B A;  5K1V A;  1Y3G E;  4JBS A;  2XQ0 A;  4ZQT A;  1FJT A;  4P8Q A;  5FSS A;  4N4E E;  2WI0 A;  4H57 A;  4RVB A;  4QME A;  3FOR A;  4XMT A;  3B2P A;  6TLI A;  3U9W A;  3T74 A;  5TMN E;  1HS6 A;  2TLX A;  3B7T A;  3FUF A;  3FTX A;  4Z7I A;  4XND A;  3ZI6 A;  1THL A;  3FU3 A;  3EBI A;  3FUJ A;  4PVB A;  4TMN E;  3PUU A;  4QUO A;  4DPR A;  6TMN E;  3P7V E;  1LNF E;  3TMN E;  2HPO A;  4FYS A;  3FTU A;  4NZ8 A;  3NN7 A;  4R7L A;  4ZW3 A;  4E36 A;  3FB0 A;  4K5O A;  1PE5 A;  3QH1 A;  1HYT A;  5JVI E;  3FTW A;  3DO0 A;  3T2I E;  4AR1 A;  3P7P E;  1LND E;  4D91 A;  1FJQ A;  4TLN A;  3NQX A;  3B7S A;  4PJ6 A;  2HPT A;  1FJ3 A;  4XO3 A;  3QGO A;  3MSF A;  4MWP E;  3FTV A;  4MKT A;  4ARF A;  3FH8 A;  1LNA E;  2A7G E;  4XO4 A;  3EBH A;  3FGD A;  4K5P A;  4XMX A;  4ZX6 A;  5A3Y A;  5L8P E;  3Q43 A;  5DPF E;  4II7 A;  3B37 A;  4N66 E;  3P7T E;  2TLI A;  5AB2 A;  5L3U E;  3B34 A;  3FH7 A;  4HOM A;  4QHP A;  4IHQ A;  3FVP A;  3FU0 A;  1FJU A;  3FV4 A;  3P7U E;  4KXA A;  4KX9 A;  3QH5 A;  3B7R L;  3Q7J A;  5CU5 A;  3MSA A;  5C97 A;  3FXP A;  3FTZ A;  1U4G A;  1KEI A;  3N21 A;  1BQB A;  2R59 A;  4FYT A;  3FUM A;  3FUN A;  7TLN A;  4MS6 A;  1KTO A;  1EZM A;  3EBG A;  4R5T A;  2VJ8 A;  2GTQ A;  4K90 A;  4OW3 A;  3F28 A;  5JXN E;  1KKK A;  4ZW6 A;  2DQM A;  3FLF A;  4XN9 A;  4Q4I A;  3B2X A;  3P7W E;  3T8F A;  4XN5 A;  4X2U A;  4MXJ E;  5K7T A;  3CHO A;  4FKH A;  1Z1W A;  3FU5 A;  4FKK A;  4N5P E;  3T2H E;  3QNF A;  2ZXG A;  5J6S A;  1Z9G E;  3FUI A;  1GXW A;  3FU6 A;  5LIF E;  3KED A;  4Q4E A;  3P7S E;  4FYR A;  4XN7 A;  4L2L A;  3TLI A;  4ZW8 A;  4K5N A;  5FXN A;  1QF0 A;  3DO2 A;  1KR6 A;  3T8G A;  3FH5 A;  5AB0 A;  3MS3 A;  4FKE A;  3FUK A;  1ZDP E;  1TLI A;  2XPZ A;  4OU3 A;  5TLI A;  3MDJ A;  5HQD A;  5EV7 A;  4MTW E;  4FGM A;  1H19 A;  5TLN A;  2VQX A;  4XMZ A;  3DO1 A;  1SQM A;  3T8D A;  1NPC A;  3FCQ A;  4RSY A;  4ZX5 A;  1LNB E;  4AR9 A;  3B7U X;  5FSJ A;  1GW6 A;  4ZX4 A;  4B52 A;  3DNZ A;  4K5L A;  2XPY A;  4XN1 A;  3SSB A;  4TNL A;  5DPE E;  8TLI A;  5JT9 E;  3FUE A;  1ESP A;  4F5C A;  4PW4 A;  7TLI A;  4AR8 A;  4XO5 A;  1KRO A;  1LNE E;  3F2P A;  4XMU A;  8TLN E;  1QF1 A;  4KX7 A;  3CHR A;  4KXB A;  4R5V A;  4XMW A;  3T8C A;  5DLH A;  3FUD A;  1FJV A;  2YD0 A;  4K5M A;  3EIM A;  3SE6 A;  4GAA A;  3T87 A;  1KJO A;  4ZW5 A;  1PE8 A;  1OS0 A;  3NQY B;  3FXS A;  3P7R E;  5AEN A;  5DLL A;  3NQZ B;  4QIR A;  5FWQ A;  4KX8 A;  3FUH A;  4PU2 A;  5FSP A;  3FUL A;  2TMN E;  1LNC E;  2DQ6 A;  1KS7 A;  1PE7 A; 
#chains in the Genus database with same CATH homology
 4XN8 A;  3FTS A;  3FH7 A;  4XND A;  3MS3 A;  3FUK A;  1TLX A;  4QPE A;  3Q44 A;  4QHP A;  1ZDP E;  1TLI A;  3FVP A;  2XPZ A;  1KJP A;  3ZI6 A;  2G4Z A;  1THL A;  3FU0 A;  3FU3 A;  1FJU A;  4XN4 A;  3FV4 A;  3EBI A;  5TLI A;  4D9W A;  5HQD A;  3P7U E;  3FUJ A;  4MTW E;  4PVB A;  4TMN E;  4ZW7 A;  3PUU A;  4QUO A;  1H19 A;  4DPR A;  5TLN A;  2VQX A;  4XMZ A;  3DO1 A;  5L41 E;  6TMN E;  1SQM A;  3QH5 A;  3T8V A;  5BPP A;  3T8G A;  3P7V E;  1LNF E;  3T8D A;  4XNA A;  3TMN E;  3B7R L;  1NPC A;  2HPO A;  3FCQ A;  4R5X A;  3FTU A;  4RSY A;  3NN7 A;  4ZX5 A;  1LNB E;  4OI5 E;  4R7L A;  4ZW3 A;  3B7U X;  3CHS A;  3FBO A;  1GW6 A;  5FSJ A;  3MSA A;  5JSS E;  4ZX4 A;  4B52 A;  3DNZ A;  4K5L A;  4MZN E;  2XPY A;  3FB0 A;  3FXP A;  3FTZ A;  4XMV A;  1U4G A;  4K5O A;  1KEI A;  3N21 A;  1BQB A;  2R59 A;  3T73 A;  4ZX3 A;  3FUM A;  4XN1 A;  3FUN A;  3T2J E;  7TLN A;  3CHQ A;  3SSB A;  4MS6 A;  1KTO A;  3MSN A;  1FJW A;  1PE5 A;  4TNL A;  3T8H A;  1EZM A;  3EBG A;  4M65 A;  5DPE E;  8TLI A;  4XNB A;  5JT9 E;  3QH1 A;  4K89 A;  1HYT A;  4R5T A;  3FTW A;  5JVI E;  3DO0 A;  3T2I E;  2VJ8 A;  2GTQ A;  3FUE A;  1LML A;  1ESP A;  3QJX A;  3F28 A;  3P7P E;  1KKK A;  4K90 A;  4OW3 A;  4ZW6 A;  5JXN E;  2DQM A;  1QF2 A;  1LND E;  3FLF A;  4TLI A;  4PW4 A;  4XN9 A;  4Q4I A;  4D91 A;  3B2X A;  3P7W E;  3T8F A;  1FJQ A;  1TRL A;  7TLI A;  4XN5 A;  4GER A;  4TLN A;  4X2U A;  1TMN E;  1KL6 A;  3NQX A;  4MXJ E;  3CHO A;  3CIA A;  3B7S A;  4XN2 A;  2WHZ A;  4XO5 A;  5K7T A;  1KRO A;  3DBK A;  1L3F E;  5LWD E;  3CHP A;  3FU5 A;  1LNE E;  3F2P A;  4XMU A;  2HPT A;  4N5P E;  8TLN E;  1QF1 A;  5JS3 E;  3T2H E;  3B3B A;  1FJ3 A;  4XO3 A;  3FTY A;  3CHR A;  2ZXG A;  3P7Q E;  4R5V A;  3QGO A;  3MSF A;  4XMW A;  4MWP E;  5DLH A;  5DYF A;  3T8C A;  3FTV A;  3FHE A;  3FUD A;  4MKT A;  1FJO A;  1TLP E;  3LS7 A;  1FJV A;  4K5M A;  1Z9G E;  4J3B A;  3EIM A;  1GXW A;  3FUI A;  3FU6 A;  4GAA A;  3T87 A;  1KJO A;  1Y3G E;  4ZQT A;  2XQ0 A;  3FH8 A;  4ZW5 A;  5LIF E;  1FJT A;  1LNA E;  5FSS A;  1PE8 A;  4N4E E;  2WI0 A;  2A7G E;  3KED A;  3P7S E;  4Q4E A;  1OS0 A;  4XN7 A;  4L2L A;  3TLI A;  4H57 A;  4XO4 A;  3EBH A;  3FGD A;  4RVB A;  4K5P A;  4ZW8 A;  3NQY B;  3FXS A;  3P7R E;  5AEN A;  4XMX A;  4QME A;  5DLL A;  4ZX6 A;  5A3Y A;  3NQZ B;  5L8P E;  3Q43 A;  3FOR A;  5DPF E;  4XMT A;  4QIR A;  4K5N A;  5FXN A;  5FWQ A;  3FUH A;  1QF0 A;  3B2P A;  4PU2 A;  6TLI A;  3B37 A;  5FSP A;  4N66 E;  3U9W A;  3FUL A;  3P7T E;  2TLI A;  3T74 A;  5TMN E;  1HS6 A;  2TMN E;  1LNC E;  2DQ6 A;  2TLX A;  1KS7 A;  5L3U E;  3B34 A;  3DO2 A;  3B7T A;  3FUF A;  3FTX A;  1PE7 A;  1KR6 A;  3FH5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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