4TLNA

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
316
structure length
316
Chain Sequence
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGDGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSEMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase (metalloproteinase)
molecule keywords THERMOLYSIN
publication title Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
pubmed doi rcsb
source organism Bacillus thermoproteolyticus
total genus 114
structure length 316
sequence length 316
ec nomenclature ec 3.4.24.27: Thermolysin.
pdb deposition date 1982-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01447 Peptidase_M4 Thermolysin metallopeptidase, catalytic domain
A PF02868 Peptidase_M4_C Thermolysin metallopeptidase, alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.390.10 Mainly Alpha Orthogonal Bundle Neutral Protease; domain 2 Neutral Protease Domain 2 4tlnA02
3.10.170.10 Alpha Beta Roll Elastase; domain 1 Elastase; domain 1 4tlnA01
4K5NA 3FU3A 5AENA 3DBKA 1EZMA 4GERA 4XN7A 5DPFE 5L3UE 7TLNA 1KKKA 1ESPA 3FTSA 1PE5A 1QF0A 4XNBA 1HS6A 4MS6A 4TLNA 1FJUA 5FWQA 4K5OA 4QIRA 3FXPA 1TLPE 4QPEA 3NQYB 4ZQTA 4MZNE 4ZW3A 8TLIA 4K89A 3P7RE 3Q43A 3U9WA 1HYTA 4XNAA 4XNDA 5BPPA 1KS7A 3KEDA 4D91A 4XMTA 4PU2A 1THLA 3FUNA 3B2XA 5FXNA 3ZI6A 3FLFA 3FTUA 2G4ZA 4XMWA 4TLIA 4XMVA 4R5XA 3TLIA 3DO2A 4PW4A 3T8DA 3N21A 4MXJE 4XN9A 3SSBA 3PUUA 3B2PA 2VQXA 3B7RL 3MSFA 2A7GE 3P7TE 4QUOA 4R7LA 4D9WA 4J3BA 4K5LA 5LWDE 5TLNA 3FBOA 4MWPE 5LIFE 4ZX5A 3CHSA 3P7WE 2DQMA 3QH1A 1TRLA 3DO1A 1LNDE 3FV4A 2VJ8A 3T8FA 1LNEE 3FORA 3FTXA 3FGDA 3B3BA 4XN4A 4ZW5A 7TLIA 3B34A 1LNFE 2XQ0A 5DLHA 3FHEA 4TNLA 1ZDPE 4MTWE 4R5VA 3T2HE 4ZX6A 2TLXA 3FCQA 3T8HA 1KTOA 1L3FE 3T87A 1TLXA 3FUJA 4N66E 4TMNE 3FXSA 3MSNA 4XO3A 1KR6A 4XN2A 4MKTA 2TMNE 3CHOA 1QF2A 1Z9GE 1SQMA 3FUHA 4QMEA 4ZW8A 3FUMA 3B37A 3FH8A 3T2JE 3TMNE 8TLNE 4N4EE 4RVBA 3DO0A 3LS7A 3FUIA 4K90A 4OI5E 3NQZB 4XN8A 4XMZA 5A3YA 5TMNE 1GXWA 3FUDA 2R59A 2XPYA 3EIMA 1KEIA 3CHQA 3FU5A 3FB0A 3CHPA 3T8GA 5JSSE 5JXNE 1KL6A 1FJTA 3FTZA 1U4GA 5FSPA 2HPOA 1NPCA 3FU6A 3FUEA 4GAAA 4XO4A 1KJOA 2TLIA 3DNZA 5JT9E 3FU0A 3FUFA 4XN5A 1LNBE 2WI0A 3FVPA 4ZW7A 3T2IE 4DPRA 2DQ6A 3P7PE 3EBIA 3FTWA 3MSAA 5L41E 4Q4EA 3QH5A 3F2PA 1FJ3A 1FJOA 2HPTA 4N5PE 5FSJA 3B7TA 2WHZA 2XPZA 4RSYA 4R5TA 2ZXGA 4QHPA 4K5PA 3NQXA 1H19A 5FSSA 3T8VA 4XN1A 3P7VE 1Y3GE 4XMXA 3P7UE 6TLIA 1FJWA 1KROA 3NN7A 5TLIA 5DPEE 4L2LA 4H57A 3F28A 4K5MA 4PVBA 3CIAA 1PE8A 1QF1A 4XO5A 3CHRA 5DLLA 3MS3A 3P7QE 5K7TA 3T74A 1TMNE 4X2UA 4OW3A 4M65A 4Q4IA 4XMUA 4ZX3A 6TMNE 1BQBA 3FH7A 3QGOA 3EBGA 3FULA 3FH5A 3B7SA 1TLIA 3Q44A 4ZW6A 5JVIE 5HQDA 3T73A 3QJXA 4B52A 1GW6A 1FJQA 3EBHA 3P7SE 3FTVA 3B7UX 3FUKA 5L8PE 1LNAE 1KJPA 1LNCE 3FTYA 5DYFA 5JS3E 4ZX4A 3T8CA 1PE7A 1OS0A 2GTQA 1FJVA
chains in the Genus database with same CATH superfamily
5AENA 1KKKA 1LMLA 1PE5A 1QF0A 3MDJA 5FWQA 1FJUA 4K5OA 3FXPA 4MZNE 3P7RE 4XNAA 4XNDA 5BPPA 1KS7A 1THLA 3ZI6A 3FTUA 3DO2A 3N21A 4XN9A 3B7RL 3MSFA 2A7GE 4QUOA 5LIFE 2DQMA 1TRLA 2VJ8A 5LHDA 3B3BA 4XN4A 7TLIA 3B34A 4FYSA 3FHEA 3T8HA 5AB2A 1L3FE 1TLXA 3FUJA 4N66E 3MSNA 4XO3A 4XN2A 2TMNE 1QF2A 1Z9GE 4ZW8A 3TMNE 3B37A 4N4EE 4RVBA 3DO0A 3FUIA 4K90A 4KX8A 4WZ9A 3CHQA 5JSSE 5JXNE 3FU6A 5JT9E 4NAQA 3T2IE 5L41E 4FYRA 4Q4EA 3QH5A 4OU3A 4K5PA 3T8VA 4XN1A 6TLIA 3NN7A 1KROA 5TLIA 4KXDA 4K5MA 3CIAA 1PE8A 4XMUA 4Q4IA 3QGOA 3Q44A 1GW6A 1LNCE 8TLIA 2GTQA 1EZMA 4KXCA 5DPFE 1ESPA 2YD0A 3FTSA 4XNBA 4MS6A 4QPEA 4ZW3A 3NQYB 4D91A 3FUNA 4KX7A 4Z7IA 4HOMA 4R5XA 5LDSA 3B2PA 3P7TE 4J3BA 4MWPE 4ZX5A 5CU5A 3DO1A 3FORA 4ZW5A 4AR9A 1LNFE 2XQ0A 4ZX6A 2TLXA 1KTOA 1SQMA 3LS7A 4XN8A 4OI5E 3EIMA 3FB0A 3FTZA 4XO4A 4GAAA 3FUEA 1KJOA 4FCAA 2WI0A 4DPRA 3P7PE 3FTWA 4FKEA 3MSAA 2HPTA 4N5PE 5FSJA 4R5TA 4RSYA 3NQXA 1H19A 5FSSA 4FKKA 4XMXA 4FKHA 5K1VA 3F28A 4XO5A 3P7QE 4OW3A 4M65A 3FH7A 5HQDA 1Z1WA 3T73A 4B52A 1FJQA 3FTVA 3B7UX 5L8PE 5JS3E 5DYFA 3T8CA 3DBKA 4NZ8A 5L3UE 1HS6A 4TLNA 1TLPE 4K89A 3Q43A 3KEDA 4FYQA 4XMTA 4PU2A 4XMWA 4XMVA 3PUUA 4D9WA 4R7LA 4K5LA 3CHSA 3QH1A 3T8FA 3FGDA 5DLHA 4FYTA 1KR6A 4MKTA 4ARFA 3CHOA 4KX9A 3T2JE 3FH8A 5TMNE 5A3YA 3FUDA 2XPYA 3FU5A 1KL6A 1FJTA 4KXAA 2HPOA 1NPCA 2TLIA 3DNZA 3FVPA 3EBIA 3F2PA 1FJ3A 3B7TA 4QHPA 2ZXGA 3P7VE 4L2LA 4PVBA 3CHRA 3MS3A 5K7TA 3T74A 4PJ6A 4X2UA 4ZX3A 5JVIE 3B7SA 4ZW6A 4AR8A 3EBHA 3P7SE 3FUKA 1LNAE 4ZX4A 1OS0A 3QJXA 1FJVA 4K5NA 3FU3A 4GERA 4XN7A 5EV7A 7TLNA 4FGMA 4QIRA 4ZQTA 3U9WA 1HYTA 4P8QA 3B2XA 5FXNA 3FLFA 2G4ZA 4TLIA 3TLIA 3T8DA 4PW4A 4MXJE 3SSBA 2VQXA 4IHQA 5LWDE 5TLNA 3FBOA 5AB0A 4JBSA 3P7WE 3Q7JA 1LNDE 3FV4A 1LNEE 3FTXA 3SE6A 5LG6A 4KXBA 4TNLA 1ZDPE 4MTWE 4R5VA 3T2HE 3FCQA 3T87A 4TMNE 3FXSA 4F5CA 3FUHA 4QMEA 8TLNE 3FUMA 3NQZB 4XMZA 1GXWA 2R59A 3CHPA 3T8GA 1U4GA 5FSPA 1Z5HA 5J6SA 3FU0A 3FUFA 4XN5A 1LNBE 4ZW7A 2DQ6A 4E36A 1FJOA 2WHZA 2XPZA 3QNFA 1Y3GE 3P7UE 1FJWA 5C97A 5DPEE 4H57A 1QF1A 5DLLA 4AR1A 1TMNE 6TMNE 1BQBA 3EBGA 3FULA 3FH5A 1TLIA 4II7A 1KJPA 3FTYA 1PE7A 1KEIA
chains in the Genus database with same CATH topology
4K5NA 3FU3A 5AENA 3DBKA 1EZMA 4GERA 4XN7A 5DPFE 5L3UE 7TLNA 1KKKA 1ESPA 1LMLA 3FTSA 1PE5A 1QF0A 4XNBA 1HS6A 4MS6A 4TLNA 1FJUA 5FWQA 4K5OA 4QIRA 3FXPA 1TLPE 4QPEA 3NQYB 4ZQTA 4MZNE 4ZW3A 8TLIA 4K89A 3P7RE 3Q43A 3U9WA 1HYTA 4XNAA 4XNDA 5BPPA 1KS7A 3KEDA 4D91A 4XMTA 4PU2A 1THLA 3FUNA 3B2XA 5FXNA 3ZI6A 3FLFA 3FTUA 2G4ZA 4XMWA 4TLIA 4XMVA 4R5XA 3TLIA 3DO2A 4PW4A 3T8DA 3N21A 4MXJE 4XN9A 3SSBA 3PUUA 3B2PA 2VQXA 3B7RL 3MSFA 2A7GE 3P7TE 4QUOA 4R7LA 4D9WA 4J3BA 4K5LA 5LWDE 5TLNA 3FBOA 4MWPE 5LIFE 4ZX5A 3CHSA 3P7WE 2DQMA 3QH1A 1TRLA 3DO1A 1LNDE 3FV4A 2VJ8A 3T8FA 1LNEE 3FORA 3FTXA 3FGDA 3B3BA 4XN4A 4ZW5A 7TLIA 3B34A 1LNFE 2XQ0A 5DLHA 3FHEA 4TNLA 1ZDPE 4MTWE 4R5VA 3T2HE 4ZX6A 2TLXA 3FCQA 3T8HA 1KTOA 1L3FE 3T87A 1TLXA 3FUJA 4N66E 4TMNE 3FXSA 3MSNA 4XO3A 1KR6A 4XN2A 4MKTA 2TMNE 3CHOA 1QF2A 1Z9GE 1SQMA 3FUHA 4QMEA 4ZW8A 3FUMA 3B37A 3FH8A 3T2JE 3TMNE 8TLNE 4N4EE 4RVBA 3DO0A 3LS7A 3FUIA 4K90A 4OI5E 3NQZB 4XN8A 4XMZA 5A3YA 5TMNE 1GXWA 3FUDA 2R59A 2XPYA 3EIMA 1KEIA 3CHQA 3FU5A 3FB0A 3CHPA 3T8GA 5JSSE 5JXNE 1KL6A 1FJTA 3FTZA 1U4GA 5FSPA 2HPOA 1NPCA 3FU6A 3FUEA 4GAAA 4XO4A 1KJOA 2TLIA 3DNZA 5JT9E 3FU0A 3FUFA 4XN5A 1LNBE 2WI0A 3FVPA 4ZW7A 3T2IE 4DPRA 2DQ6A 3P7PE 3EBIA 3FTWA 3MSAA 5L41E 4Q4EA 3QH5A 3F2PA 1FJ3A 1FJOA 2HPTA 4N5PE 5FSJA 3B7TA 2WHZA 2XPZA 4RSYA 4R5TA 2ZXGA 4QHPA 4K5PA 3NQXA 1H19A 5FSSA 3T8VA 4XN1A 3P7VE 1Y3GE 4XMXA 3P7UE 6TLIA 1FJWA 1KROA 3NN7A 5TLIA 5DPEE 4L2LA 4H57A 3F28A 4K5MA 4PVBA 3CIAA 1PE8A 1QF1A 4XO5A 3CHRA 5DLLA 3MS3A 3P7QE 5K7TA 3T74A 1TMNE 4X2UA 4OW3A 4M65A 4Q4IA 4XMUA 4ZX3A 6TMNE 1BQBA 3FH7A 3QGOA 3EBGA 3FULA 3FH5A 3B7SA 1TLIA 3Q44A 4ZW6A 5JVIE 5HQDA 3T73A 3QJXA 4B52A 1GW6A 1FJQA 3EBHA 3P7SE 3FTVA 3B7UX 3FUKA 5L8PE 1LNAE 1KJPA 1LNCE 3FTYA 5DYFA 5JS3E 4ZX4A 3T8CA 1PE7A 1OS0A 2GTQA 1FJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K5N A;  3FU3 A;  5AEN A;  3DBK A;  1EZM A;  4GER A;  4XN7 A;  5DPF E;  5L3U E;  7TLN A;  1KKK A;  1ESP A;  3FTS A;  1PE5 A;  1QF0 A;  4XNB A;  1HS6 A;  4MS6 A;  4TLN A;  1FJU A;  5FWQ A;  4K5O A;  4QIR A;  3FXP A;  1TLP E;  4QPE A;  3NQY B;  4ZQT A;  4MZN E;  4ZW3 A;  8TLI A;  4K89 A;  3P7R E;  3Q43 A;  3U9W A;  1HYT A;  4XNA A;  4XND A;  5BPP A;  1KS7 A;  3KED A;  4D91 A;  4XMT A;  4PU2 A;  1THL A;  3FUN A;  3B2X A;  5FXN A;  3ZI6 A;  3FLF A;  3FTU A;  2G4Z A;  4XMW A;  4TLI A;  4XMV A;  4R5X A;  3TLI A;  3DO2 A;  4PW4 A;  3T8D A;  3N21 A;  4MXJ E;  4XN9 A;  3SSB A;  3PUU A;  3B2P A;  2VQX A;  3B7R L;  3MSF A;  2A7G E;  3P7T E;  4QUO A;  4R7L A;  4D9W A;  4J3B A;  4K5L A;  5LWD E;  5TLN A;  3FBO A;  4MWP E;  5LIF E;  4ZX5 A;  3CHS A;  3P7W E;  2DQM A;  3QH1 A;  1TRL A;  3DO1 A;  1LND E;  3FV4 A;  2VJ8 A;  3T8F A;  1LNE E;  3FOR A;  3FTX A;  3FGD A;  3B3B A;  4XN4 A;  4ZW5 A;  7TLI A;  3B34 A;  1LNF E;  2XQ0 A;  5DLH A;  3FHE A;  4TNL A;  1ZDP E;  4MTW E;  4R5V A;  3T2H E;  4ZX6 A;  2TLX A;  3FCQ A;  3T8H A;  1KTO A;  1L3F E;  3T87 A;  1TLX A;  3FUJ A;  4N66 E;  4TMN E;  3FXS A;  3MSN A;  4XO3 A;  1KR6 A;  4XN2 A;  4MKT A;  2TMN E;  3CHO A;  1QF2 A;  1Z9G E;  1SQM A;  3FUH A;  4QME A;  4ZW8 A;  3FUM A;  3B37 A;  3FH8 A;  3T2J E;  3TMN E;  8TLN E;  4N4E E;  4RVB A;  3DO0 A;  3LS7 A;  3FUI A;  4K90 A;  4OI5 E;  3NQZ B;  4XN8 A;  4XMZ A;  5A3Y A;  5TMN E;  1GXW A;  3FUD A;  2R59 A;  2XPY A;  3EIM A;  1KEI A;  3CHQ A;  3FU5 A;  3FB0 A;  3CHP A;  3T8G A;  5JSS E;  5JXN E;  1KL6 A;  1FJT A;  3FTZ A;  1U4G A;  5FSP A;  2HPO A;  1NPC A;  3FU6 A;  3FUE A;  4GAA A;  4XO4 A;  1KJO A;  2TLI A;  3DNZ A;  5JT9 E;  3FU0 A;  3FUF A;  4XN5 A;  1LNB E;  2WI0 A;  3FVP A;  4ZW7 A;  3T2I E;  4DPR A;  2DQ6 A;  3P7P E;  3EBI A;  3FTW A;  3MSA A;  5L41 E;  4Q4E A;  3QH5 A;  3F2P A;  1FJ3 A;  1FJO A;  2HPT A;  4N5P E;  5FSJ A;  3B7T A;  2WHZ A;  2XPZ A;  4RSY A;  4R5T A;  2ZXG A;  4QHP A;  4K5P A;  3NQX A;  1H19 A;  5FSS A;  3T8V A;  4XN1 A;  3P7V E;  1Y3G E;  4XMX A;  3P7U E;  6TLI A;  1FJW A;  1KRO A;  3NN7 A;  5TLI A;  5DPE E;  4L2L A;  4H57 A;  3F28 A;  4K5M A;  4PVB A;  3CIA A;  1PE8 A;  1QF1 A;  4XO5 A;  3CHR A;  5DLL A;  3MS3 A;  3P7Q E;  5K7T A;  3T74 A;  1TMN E;  4X2U A;  4OW3 A;  4M65 A;  4Q4I A;  4XMU A;  4ZX3 A;  6TMN E;  1BQB A;  3FH7 A;  3QGO A;  3EBG A;  3FUL A;  3FH5 A;  3B7S A;  1TLI A;  3Q44 A;  4ZW6 A;  5JVI E;  5HQD A;  3T73 A;  3QJX A;  4B52 A;  1GW6 A;  1FJQ A;  3EBH A;  3P7S E;  3FTV A;  3B7U X;  3FUK A;  5L8P E;  1LNA E;  1KJP A;  1LNC E;  3FTY A;  5DYF A;  5JS3 E;  4ZX4 A;  3T8C A;  1PE7 A;  1OS0 A;  2GTQ A;  1FJV A; 
#chains in the Genus database with same CATH topology
 5AEN A;  1KKK A;  1LML A;  1PE5 A;  1QF0 A;  3MDJ A;  5FWQ A;  1FJU A;  4K5O A;  3FXP A;  4MZN E;  3P7R E;  4XNA A;  4XND A;  5BPP A;  1KS7 A;  1THL A;  3ZI6 A;  3FTU A;  3DO2 A;  3N21 A;  4XN9 A;  3B7R L;  3MSF A;  2A7G E;  4QUO A;  5LIF E;  2DQM A;  1TRL A;  2VJ8 A;  5LHD A;  3B3B A;  4XN4 A;  7TLI A;  3B34 A;  4FYS A;  3FHE A;  3T8H A;  5AB2 A;  1L3F E;  1TLX A;  3FUJ A;  4N66 E;  3MSN A;  4XO3 A;  4XN2 A;  2TMN E;  1QF2 A;  1Z9G E;  4ZW8 A;  3TMN E;  3B37 A;  4N4E E;  4RVB A;  3DO0 A;  3FUI A;  4K90 A;  4KX8 A;  4WZ9 A;  3CHQ A;  5JSS E;  5JXN E;  3FU6 A;  5JT9 E;  4NAQ A;  3T2I E;  5L41 E;  4FYR A;  4Q4E A;  3QH5 A;  4OU3 A;  4K5P A;  3T8V A;  4XN1 A;  6TLI A;  3NN7 A;  1KRO A;  5TLI A;  4KXD A;  4K5M A;  3CIA A;  1PE8 A;  4XMU A;  4Q4I A;  3QGO A;  3Q44 A;  1GW6 A;  1LNC E;  8TLI A;  2GTQ A;  1EZM A;  4KXC A;  5DPF E;  1ESP A;  2YD0 A;  3FTS A;  4XNB A;  4MS6 A;  4QPE A;  4ZW3 A;  3NQY B;  4D91 A;  3FUN A;  4KX7 A;  4Z7I A;  4HOM A;  4R5X A;  5LDS A;  3B2P A;  3P7T E;  4J3B A;  4MWP E;  4ZX5 A;  5CU5 A;  3DO1 A;  3FOR A;  4ZW5 A;  4AR9 A;  1LNF E;  2XQ0 A;  4ZX6 A;  2TLX A;  1KTO A;  1SQM A;  3LS7 A;  4XN8 A;  4OI5 E;  3EIM A;  3FB0 A;  3FTZ A;  4XO4 A;  4GAA A;  3FUE A;  1KJO A;  4FCA A;  2WI0 A;  4DPR A;  3P7P E;  3FTW A;  4FKE A;  3MSA A;  2HPT A;  4N5P E;  5FSJ A;  4R5T A;  4RSY A;  3NQX A;  1H19 A;  5FSS A;  4FKK A;  4XMX A;  4FKH A;  5K1V A;  3F28 A;  4XO5 A;  3P7Q E;  4OW3 A;  4M65 A;  3FH7 A;  5HQD A;  1Z1W A;  3T73 A;  4B52 A;  1FJQ A;  3FTV A;  3B7U X;  5L8P E;  5JS3 E;  5DYF A;  3T8C A;  3DBK A;  4NZ8 A;  5L3U E;  1HS6 A;  4TLN A;  1TLP E;  4K89 A;  3Q43 A;  3KED A;  4FYQ A;  4XMT A;  4PU2 A;  4XMW A;  4XMV A;  3PUU A;  4D9W A;  4R7L A;  4K5L A;  3CHS A;  3QH1 A;  3T8F A;  3FGD A;  5DLH A;  4FYT A;  1KR6 A;  4MKT A;  4ARF A;  3CHO A;  4KX9 A;  3T2J E;  3FH8 A;  5TMN E;  5A3Y A;  3FUD A;  2XPY A;  3FU5 A;  1KL6 A;  1FJT A;  4KXA A;  2HPO A;  1NPC A;  2TLI A;  3DNZ A;  3FVP A;  3EBI A;  3F2P A;  1FJ3 A;  3B7T A;  4QHP A;  2ZXG A;  3P7V E;  4L2L A;  4PVB A;  3CHR A;  3MS3 A;  5K7T A;  3T74 A;  4PJ6 A;  4X2U A;  4ZX3 A;  5JVI E;  3B7S A;  4ZW6 A;  4AR8 A;  3EBH A;  3P7S E;  3FUK A;  1LNA E;  4ZX4 A;  1OS0 A;  3QJX A;  1FJV A;  4K5N A;  3FU3 A;  4GER A;  4XN7 A;  5EV7 A;  7TLN A;  4FGM A;  4QIR A;  4ZQT A;  3U9W A;  1HYT A;  4P8Q A;  3B2X A;  5FXN A;  3FLF A;  2G4Z A;  4TLI A;  3TLI A;  3T8D A;  4PW4 A;  4MXJ E;  3SSB A;  2VQX A;  4IHQ A;  5LWD E;  5TLN A;  3FBO A;  5AB0 A;  4JBS A;  3P7W E;  3Q7J A;  1LND E;  3FV4 A;  1LNE E;  3FTX A;  3SE6 A;  5LG6 A;  4KXB A;  4TNL A;  1ZDP E;  4MTW E;  4R5V A;  3T2H E;  3FCQ A;  3T87 A;  4TMN E;  3FXS A;  4F5C A;  3FUH A;  4QME A;  8TLN E;  3FUM A;  3NQZ B;  4XMZ A;  1GXW A;  2R59 A;  3CHP A;  3T8G A;  1U4G A;  5FSP A;  1Z5H A;  5J6S A;  3FU0 A;  3FUF A;  4XN5 A;  1LNB E;  4ZW7 A;  2DQ6 A;  4E36 A;  1FJO A;  2WHZ A;  2XPZ A;  3QNF A;  1Y3G E;  3P7U E;  1FJW A;  5C97 A;  5DPE E;  4H57 A;  1QF1 A;  5DLL A;  4AR1 A;  1TMN E;  6TMN E;  1BQB A;  3EBG A;  3FUL A;  3FH5 A;  1TLI A;  4II7 A;  1KJP A;  3FTY A;  1PE7 A;  1KEI A; 
#chains in the Genus database with same CATH homology
 4K5N A;  3FU3 A;  5AEN A;  3DBK A;  1EZM A;  4GER A;  4XN7 A;  5DPF E;  5L3U E;  7TLN A;  1KKK A;  1ESP A;  1LML A;  3FTS A;  1PE5 A;  1QF0 A;  4XNB A;  1HS6 A;  4MS6 A;  4TLN A;  1FJU A;  5FWQ A;  4K5O A;  4QIR A;  3FXP A;  1TLP E;  4QPE A;  3NQY B;  4ZQT A;  4MZN E;  4ZW3 A;  8TLI A;  4K89 A;  3P7R E;  3Q43 A;  3U9W A;  1HYT A;  4XNA A;  4XND A;  5BPP A;  1KS7 A;  3KED A;  4D91 A;  4XMT A;  4PU2 A;  1THL A;  3FUN A;  3B2X A;  5FXN A;  3ZI6 A;  3FLF A;  3FTU A;  2G4Z A;  4XMW A;  4TLI A;  4XMV A;  4R5X A;  3TLI A;  3DO2 A;  4PW4 A;  3T8D A;  3N21 A;  4MXJ E;  4XN9 A;  3SSB A;  3PUU A;  3B2P A;  2VQX A;  3B7R L;  3MSF A;  2A7G E;  3P7T E;  4QUO A;  4R7L A;  4D9W A;  4J3B A;  4K5L A;  5LWD E;  5TLN A;  3FBO A;  4MWP E;  5LIF E;  4ZX5 A;  3CHS A;  3P7W E;  2DQM A;  3QH1 A;  1TRL A;  3DO1 A;  1LND E;  3FV4 A;  2VJ8 A;  3T8F A;  1LNE E;  3FOR A;  3FTX A;  3FGD A;  3B3B A;  4XN4 A;  4ZW5 A;  7TLI A;  3B34 A;  1LNF E;  2XQ0 A;  5DLH A;  3FHE A;  4TNL A;  1ZDP E;  4MTW E;  4R5V A;  3T2H E;  4ZX6 A;  2TLX A;  3FCQ A;  3T8H A;  1KTO A;  1L3F E;  3T87 A;  1TLX A;  3FUJ A;  4N66 E;  4TMN E;  3FXS A;  3MSN A;  4XO3 A;  1KR6 A;  4XN2 A;  4MKT A;  2TMN E;  3CHO A;  1QF2 A;  1Z9G E;  1SQM A;  3FUH A;  4QME A;  4ZW8 A;  3FUM A;  3B37 A;  3FH8 A;  3T2J E;  3TMN E;  8TLN E;  4N4E E;  4RVB A;  3DO0 A;  3LS7 A;  3FUI A;  4K90 A;  4OI5 E;  3NQZ B;  4XN8 A;  4XMZ A;  5A3Y A;  5TMN E;  1GXW A;  3FUD A;  2R59 A;  2XPY A;  3EIM A;  1KEI A;  3CHQ A;  3FU5 A;  3FB0 A;  3CHP A;  3T8G A;  5JSS E;  5JXN E;  1KL6 A;  1FJT A;  3FTZ A;  1U4G A;  5FSP A;  2HPO A;  1NPC A;  3FU6 A;  3FUE A;  4GAA A;  4XO4 A;  1KJO A;  2TLI A;  3DNZ A;  5JT9 E;  3FU0 A;  3FUF A;  4XN5 A;  1LNB E;  2WI0 A;  3FVP A;  4ZW7 A;  3T2I E;  4DPR A;  2DQ6 A;  3P7P E;  3EBI A;  3FTW A;  3MSA A;  5L41 E;  4Q4E A;  3QH5 A;  3F2P A;  1FJ3 A;  1FJO A;  2HPT A;  4N5P E;  5FSJ A;  3B7T A;  2WHZ A;  2XPZ A;  4RSY A;  4R5T A;  2ZXG A;  4QHP A;  4K5P A;  3NQX A;  1H19 A;  5FSS A;  3T8V A;  4XN1 A;  3P7V E;  1Y3G E;  4XMX A;  3P7U E;  6TLI A;  1FJW A;  1KRO A;  3NN7 A;  5TLI A;  5DPE E;  4L2L A;  4H57 A;  3F28 A;  4K5M A;  4PVB A;  3CIA A;  1PE8 A;  1QF1 A;  4XO5 A;  3CHR A;  5DLL A;  3MS3 A;  3P7Q E;  5K7T A;  3T74 A;  1TMN E;  4X2U A;  4OW3 A;  4M65 A;  4Q4I A;  4XMU A;  4ZX3 A;  6TMN E;  1BQB A;  3FH7 A;  3QGO A;  3EBG A;  3FUL A;  3FH5 A;  3B7S A;  1TLI A;  3Q44 A;  4ZW6 A;  5JVI E;  5HQD A;  3T73 A;  3QJX A;  4B52 A;  1GW6 A;  1FJQ A;  3EBH A;  3P7S E;  3FTV A;  3B7U X;  3FUK A;  5L8P E;  1LNA E;  1KJP A;  1LNC E;  3FTY A;  5DYF A;  5JS3 E;  4ZX4 A;  3T8C A;  1PE7 A;  1OS0 A;  2GTQ A;  1FJV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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