1TWQA

Crystal structure of the c-terminal pgn-binding domain of human pgrp-ialpha in complex with pgn analog muramyl tripeptide
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
165
structure length
165
Chain Sequence
VCPNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHFKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for peptidoglycan binding by peptidoglycan recognition proteins
pubmed doi rcsb
molecule tags Immune system, membrane protein
source organism Homo sapiens
molecule keywords peptidoglycan recognition protein-I-alpha
total genus 53
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2004-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 1twqA00
1SXRA 2R90A 3NNOA 2CB3A 1AROL 4Q8SA 2RKQA 4IVVA 3LATA 1SK4A 2F2LA 4KNKA 3D2YA 2WKXA 3HMBA 5E0AA 5E0BA 3CORA 2EAXA 4GF9A 2Y2CA 4BXEA 3C2XA 4BOLA 2Y2DA 3QJ1A 3T39A 4FNNA 1YB0A 3RT4A 5DWFA 3EP1A 2AR3A 2L47A 2F2LX 3CXAA 3UMQA 2BH7A 4OUGA 2XZ8A 4BXDA 1YCKA 2Z9NA 1SK3A 2XZ4A 2Y2BA 2Y28A 4ORVA 1S2JA 2EAVA 3CG9A 2APHA 4BPAA 1Z6IA 4KNLA 3O4KA 2R2KA 1J3GA 3NG4A 3D2ZA 4OPPA 3UILA 2Y2EA 3USXA 4OLSA 4Z8IA 3NW3A 1LBAA 3OGXA 5CTVA 4ZXMA 3TRUA 3UMLA 3RDRA 3QV4A 1TWQA 3QS0A 3T2VA 1OHTA 4BJ4A 4Q9EA 4BXJA 4X36A
chains in the Genus database with same CATH superfamily
1SXRA 2R90A 3NNOA 2CB3A 1AROL 4Q8SA 2RKQA 4IVVA 3LATA 1SK4A 2F2LA 4KNKA 3D2YA 2WKXA 3HMBA 5E0AA 5E0BA 3CORA 2EAXA 4GF9A 2Y2CA 4BXEA 3C2XA 4BOLA 2Y2DA 3QJ1A 3T39A 4FNNA 1YB0A 3RT4A 5DWFA 3EP1A 2AR3A 2L47A 2F2LX 3CXAA 3UMQA 2BH7A 4OUGA 2XZ8A 4BXDA 1YCKA 2Z9NA 1SK3A 2XZ4A 2Y2BA 2Y28A 4ORVA 1S2JA 2EAVA 3CG9A 2APHA 4BPAA 1Z6IA 4KNLA 3O4KA 2R2KA 1J3GA 3NG4A 3D2ZA 4OPPA 3UILA 2Y2EA 3USXA 4OLSA 4Z8IA 3NW3A 1LBAA 3OGXA 5CTVA 4ZXMA 3TRUA 3UMLA 3RDRA 3QV4A 1TWQA 3QS0A 3T2VA 1OHTA 4BJ4A 4Q9EA 4BXJA 4X36A
chains in the Genus database with same CATH topology
1SXRA 2R90A 3NNOA 2CB3A 1AROL 4Q8SA 2RKQA 4IVVA 3LATA 1SK4A 2F2LA 4KNKA 3D2YA 2WKXA 3HMBA 5E0AA 5E0BA 3CORA 2EAXA 4GF9A 2Y2CA 4BXEA 3C2XA 4BOLA 2Y2DA 3QJ1A 3T39A 4FNNA 1YB0A 3RT4A 5DWFA 3EP1A 2AR3A 2L47A 2F2LX 3CXAA 3UMQA 2BH7A 4OUGA 2XZ8A 4BXDA 1YCKA 2Z9NA 1SK3A 2XZ4A 2Y2BA 2Y28A 4ORVA 1S2JA 2EAVA 3CG9A 2APHA 4BPAA 1Z6IA 4KNLA 3O4KA 2R2KA 1J3GA 3NG4A 3D2ZA 4OPPA 3UILA 2Y2EA 3USXA 4OLSA 4Z8IA 3NW3A 1LBAA 3OGXA 5CTVA 4ZXMA 3TRUA 3UMLA 3RDRA 3QV4A 1TWQA 3QS0A 3T2VA 1OHTA 4BJ4A 4Q9EA 4BXJA 4X36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SXR A;  2R90 A;  3NNO A;  2CB3 A;  1ARO L;  4Q8S A;  2RKQ A;  4IVV A;  3LAT A;  1SK4 A;  2F2L A;  4KNK A;  3D2Y A;  2WKX A;  3HMB A;  5E0A A;  5E0B A;  3COR A;  2EAX A;  4GF9 A;  2Y2C A;  4BXE A;  3C2X A;  4BOL A;  2Y2D A;  3QJ1 A;  3T39 A;  4FNN A;  1YB0 A;  3RT4 A;  5DWF A;  3EP1 A;  2AR3 A;  2L47 A;  2F2L X;  3CXA A;  3UMQ A;  2BH7 A;  4OUG A;  2XZ8 A;  4BXD A;  1YCK A;  2Z9N A;  1SK3 A;  2XZ4 A;  2Y2B A;  2Y28 A;  4ORV A;  1S2J A;  2EAV A;  3CG9 A;  2APH A;  4BPA A;  1Z6I A;  4KNL A;  3O4K A;  2R2K A;  1J3G A;  3NG4 A;  3D2Z A;  4OPP A;  3UIL A;  2Y2E A;  3USX A;  4OLS A;  4Z8I A;  3NW3 A;  1LBA A;  3OGX A;  5CTV A;  4ZXM A;  3TRU A;  3UML A;  3RDR A;  3QV4 A;  1TWQ A;  3QS0 A;  3T2V A;  1OHT A;  4BJ4 A;  4Q9E A;  4BXJ A;  4X36 A; 
#chains in the Genus database with same CATH topology
 1SXR A;  2R90 A;  3NNO A;  2CB3 A;  1ARO L;  4Q8S A;  2RKQ A;  4IVV A;  3LAT A;  1SK4 A;  2F2L A;  4KNK A;  3D2Y A;  2WKX A;  3HMB A;  5E0A A;  5E0B A;  3COR A;  2EAX A;  4GF9 A;  2Y2C A;  4BXE A;  3C2X A;  4BOL A;  2Y2D A;  3QJ1 A;  3T39 A;  4FNN A;  1YB0 A;  3RT4 A;  5DWF A;  3EP1 A;  2AR3 A;  2L47 A;  2F2L X;  3CXA A;  3UMQ A;  2BH7 A;  4OUG A;  2XZ8 A;  4BXD A;  1YCK A;  2Z9N A;  1SK3 A;  2XZ4 A;  2Y2B A;  2Y28 A;  4ORV A;  1S2J A;  2EAV A;  3CG9 A;  2APH A;  4BPA A;  1Z6I A;  4KNL A;  3O4K A;  2R2K A;  1J3G A;  3NG4 A;  3D2Z A;  4OPP A;  3UIL A;  2Y2E A;  3USX A;  4OLS A;  4Z8I A;  3NW3 A;  1LBA A;  3OGX A;  5CTV A;  4ZXM A;  3TRU A;  3UML A;  3RDR A;  3QV4 A;  1TWQ A;  3QS0 A;  3T2V A;  1OHT A;  4BJ4 A;  4Q9E A;  4BXJ A;  4X36 A; 
#chains in the Genus database with same CATH homology
 1SXR A;  2R90 A;  3NNO A;  2CB3 A;  1ARO L;  4Q8S A;  2RKQ A;  4IVV A;  3LAT A;  1SK4 A;  2F2L A;  4KNK A;  3D2Y A;  2WKX A;  3HMB A;  5E0A A;  5E0B A;  3COR A;  2EAX A;  4GF9 A;  2Y2C A;  4BXE A;  3C2X A;  4BOL A;  2Y2D A;  3QJ1 A;  3T39 A;  4FNN A;  1YB0 A;  3RT4 A;  5DWF A;  3EP1 A;  2AR3 A;  2L47 A;  2F2L X;  3CXA A;  3UMQ A;  2BH7 A;  4OUG A;  2XZ8 A;  4BXD A;  1YCK A;  2Z9N A;  1SK3 A;  2XZ4 A;  2Y2B A;  2Y28 A;  4ORV A;  1S2J A;  2EAV A;  3CG9 A;  2APH A;  4BPA A;  1Z6I A;  4KNL A;  3O4K A;  2R2K A;  1J3G A;  3NG4 A;  3D2Z A;  4OPP A;  3UIL A;  2Y2E A;  3USX A;  4OLS A;  4Z8I A;  3NW3 A;  1LBA A;  3OGX A;  5CTV A;  4ZXM A;  3TRU A;  3UML A;  3RDR A;  3QV4 A;  1TWQ A;  3QS0 A;  3T2V A;  1OHT A;  4BJ4 A;  4Q9E A;  4BXJ A;  4X36 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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