5CTVA

Catalytic domain of lyta, the major autolysin of streptococcus pneumoniae, (c60a, h133a, c136a mutant) complexed with peptidoglycan fragment
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
176
structure length
176
Chain Sequence
ASMEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGAIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTAEYATNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.
pubmed doi rcsb
molecule keywords Autolysin
molecule tags Hydrolase
source organism Streptococcus pneumoniae serotype 4
total genus 65
structure length 176
sequence length 176
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2015-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 5ctvA00
4X36A 4ORVA 2WKXA 2R2KA 3T2VA 3EP1A 2CB3A 4GF9A 5DWFA 2Y28A 3NG4A 5E0AA 3O4KA 3HMBA 3QJ1A 2F2LA 3CXAA 5CTVA 3LATA 4BXDA 2RKQA 3NNOA 3OGXA 1YCKA 4Z8IA 4BPAA 1OHTA 3RDRA 2AR3A 4BJ4A 3UILA 3NW3A 2XZ4A 4BXEA 4OUGA 2Z9NA 2XZ8A 4IVVA 2Y2DA 3UMQA 2EAXA 3D2ZA 1SK3A 4OLSA 2APHA 3T39A 2R90A 2F2LX 1TWQA 2BH7A 4BXJA 1S2JA 3TRUA 4Q9EA 2Y2BA 3CG9A 3RT4A 1Z6IA 4BOLA 2L47A 1YB0A 3UMLA 3CORA 1LBAA 3D2YA 1SXRA 3QV4A 3C2XA 1AROL 4FNNA 4ZXMA 3USXA 2Y2EA 4OPPA 4Q8SA 1SK4A 2Y2CA 1J3GA 4KNLA 5E0BA 2EAVA 4KNKA 3QS0A
chains in the Genus database with same CATH superfamily
4X36A 4ORVA 2WKXA 2R2KA 3T2VA 3EP1A 2CB3A 4GF9A 5DWFA 2Y28A 3NG4A 5E0AA 3O4KA 3HMBA 3QJ1A 2F2LA 3CXAA 5CTVA 3LATA 4BXDA 2RKQA 3NNOA 3OGXA 1YCKA 4Z8IA 4BPAA 1OHTA 3RDRA 2AR3A 4BJ4A 3UILA 3NW3A 2XZ4A 4BXEA 4OUGA 2Z9NA 2XZ8A 4IVVA 2Y2DA 3UMQA 2EAXA 3D2ZA 1SK3A 4OLSA 2APHA 3T39A 2R90A 2F2LX 1TWQA 2BH7A 4BXJA 1S2JA 3TRUA 4Q9EA 2Y2BA 3CG9A 3RT4A 1Z6IA 4BOLA 2L47A 1YB0A 3UMLA 3CORA 1LBAA 3D2YA 1SXRA 3QV4A 3C2XA 1AROL 4FNNA 4ZXMA 3USXA 2Y2EA 4OPPA 4Q8SA 1SK4A 2Y2CA 1J3GA 4KNLA 5E0BA 2EAVA 4KNKA 3QS0A
chains in the Genus database with same CATH topology
4X36A 4ORVA 2WKXA 2R2KA 3T2VA 3EP1A 2CB3A 4GF9A 5DWFA 2Y28A 3NG4A 5E0AA 3O4KA 3HMBA 3QJ1A 2F2LA 3CXAA 5CTVA 3LATA 4BXDA 2RKQA 3NNOA 3OGXA 1YCKA 4Z8IA 4BPAA 1OHTA 3RDRA 2AR3A 4BJ4A 3UILA 3NW3A 2XZ4A 4BXEA 4OUGA 2Z9NA 2XZ8A 4IVVA 2Y2DA 3UMQA 2EAXA 3D2ZA 1SK3A 4OLSA 2APHA 3T39A 2R90A 2F2LX 1TWQA 2BH7A 4BXJA 1S2JA 3TRUA 4Q9EA 2Y2BA 3CG9A 3RT4A 1Z6IA 4BOLA 2L47A 1YB0A 3UMLA 3CORA 1LBAA 3D2YA 1SXRA 3QV4A 3C2XA 1AROL 4FNNA 4ZXMA 3USXA 2Y2EA 4OPPA 4Q8SA 1SK4A 2Y2CA 1J3GA 4KNLA 5E0BA 2EAVA 4KNKA 3QS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X36 A;  4ORV A;  2WKX A;  2R2K A;  3T2V A;  3EP1 A;  2CB3 A;  4GF9 A;  5DWF A;  2Y28 A;  3NG4 A;  5E0A A;  3O4K A;  3HMB A;  3QJ1 A;  2F2L A;  3CXA A;  5CTV A;  3LAT A;  4BXD A;  2RKQ A;  3NNO A;  3OGX A;  1YCK A;  4Z8I A;  4BPA A;  1OHT A;  3RDR A;  2AR3 A;  4BJ4 A;  3UIL A;  3NW3 A;  2XZ4 A;  4BXE A;  4OUG A;  2Z9N A;  2XZ8 A;  4IVV A;  2Y2D A;  3UMQ A;  2EAX A;  3D2Z A;  1SK3 A;  4OLS A;  2APH A;  3T39 A;  2R90 A;  2F2L X;  1TWQ A;  2BH7 A;  4BXJ A;  1S2J A;  3TRU A;  4Q9E A;  2Y2B A;  3CG9 A;  3RT4 A;  1Z6I A;  4BOL A;  2L47 A;  1YB0 A;  3UML A;  3COR A;  1LBA A;  3D2Y A;  1SXR A;  3QV4 A;  3C2X A;  1ARO L;  4FNN A;  4ZXM A;  3USX A;  2Y2E A;  4OPP A;  4Q8S A;  1SK4 A;  2Y2C A;  1J3G A;  4KNL A;  5E0B A;  2EAV A;  4KNK A;  3QS0 A; 
#chains in the Genus database with same CATH topology
 4X36 A;  4ORV A;  2WKX A;  2R2K A;  3T2V A;  3EP1 A;  2CB3 A;  4GF9 A;  5DWF A;  2Y28 A;  3NG4 A;  5E0A A;  3O4K A;  3HMB A;  3QJ1 A;  2F2L A;  3CXA A;  5CTV A;  3LAT A;  4BXD A;  2RKQ A;  3NNO A;  3OGX A;  1YCK A;  4Z8I A;  4BPA A;  1OHT A;  3RDR A;  2AR3 A;  4BJ4 A;  3UIL A;  3NW3 A;  2XZ4 A;  4BXE A;  4OUG A;  2Z9N A;  2XZ8 A;  4IVV A;  2Y2D A;  3UMQ A;  2EAX A;  3D2Z A;  1SK3 A;  4OLS A;  2APH A;  3T39 A;  2R90 A;  2F2L X;  1TWQ A;  2BH7 A;  4BXJ A;  1S2J A;  3TRU A;  4Q9E A;  2Y2B A;  3CG9 A;  3RT4 A;  1Z6I A;  4BOL A;  2L47 A;  1YB0 A;  3UML A;  3COR A;  1LBA A;  3D2Y A;  1SXR A;  3QV4 A;  3C2X A;  1ARO L;  4FNN A;  4ZXM A;  3USX A;  2Y2E A;  4OPP A;  4Q8S A;  1SK4 A;  2Y2C A;  1J3G A;  4KNL A;  5E0B A;  2EAV A;  4KNK A;  3QS0 A; 
#chains in the Genus database with same CATH homology
 4X36 A;  4ORV A;  2WKX A;  2R2K A;  3T2V A;  3EP1 A;  2CB3 A;  4GF9 A;  5DWF A;  2Y28 A;  3NG4 A;  5E0A A;  3O4K A;  3HMB A;  3QJ1 A;  2F2L A;  3CXA A;  5CTV A;  3LAT A;  4BXD A;  2RKQ A;  3NNO A;  3OGX A;  1YCK A;  4Z8I A;  4BPA A;  1OHT A;  3RDR A;  2AR3 A;  4BJ4 A;  3UIL A;  3NW3 A;  2XZ4 A;  4BXE A;  4OUG A;  2Z9N A;  2XZ8 A;  4IVV A;  2Y2D A;  3UMQ A;  2EAX A;  3D2Z A;  1SK3 A;  4OLS A;  2APH A;  3T39 A;  2R90 A;  2F2L X;  1TWQ A;  2BH7 A;  4BXJ A;  1S2J A;  3TRU A;  4Q9E A;  2Y2B A;  3CG9 A;  3RT4 A;  1Z6I A;  4BOL A;  2L47 A;  1YB0 A;  3UML A;  3COR A;  1LBA A;  3D2Y A;  1SXR A;  3QV4 A;  3C2X A;  1ARO L;  4FNN A;  4ZXM A;  3USX A;  2Y2E A;  4OPP A;  4Q8S A;  1SK4 A;  2Y2C A;  1J3G A;  4KNL A;  5E0B A;  2EAV A;  4KNK A;  3QS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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