1VHHA

A potential catalytic site within the amino-terminal signalling domain of sonic hedgehog
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
157
structure length
157
Chain Sequence
KLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signalling protein
source organism Mus musculus
publication title A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
pubmed doi rcsb
molecule keywords SONIC HEDGEHOG
total genus 45
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 1995-10-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 1vhhA00
1U10A 3N1GA 1R44A 2IBGE 3K7IB 4OAKA 2WFRA 2WFXA 5HNMA 4MURA 4OXDA 3K7JB 3N1QA 4OX5A 4MPHA 3MXWA 4OX3A 4MUSA 1LBUA 4NT9A 2WG4A 3N1RA 4JIDA 3N1PB 3M1NA 3N1MB 2WFQA 1TZPA 1VHHA 3K7HB 3K7GB 4C4NA 4F78A 3N1FA 4C4MA 4D0YA 3D1MA 2VO9A 4MUQA 3N1OA 2WG3A 3HO5H 4MUTA
chains in the Genus database with same CATH superfamily
1U10A 3N1GA 4OAKA 2IBGE 2C0JA 2CFHA 3K7IB 2J3WB 2J3TB 2BJNA 2WFRA 2WFXA 5HNMA 3KXCC 2J3RB 4MURA 4OXDA 1WC9A 3K7JB 3N1QA 4OX5A 4MPHA 3MXWA 4OX3A 2C0JB 4MUSA 1WC8A 1LBUA 2OSOA 4NT9A 2WG4A 3N1RA 4JIDA 3KXCA 3N1PB 3M1NA 2OSDA 3CUED 3HO5H 3N1MB 2WFQA 1TZPA 1VHHA 3K7HB 3K7GB 4C4NA 3NJCA 4F78A 3N1FA 3CUEB 2J3TA 1SZ7A 2CFHC 4C4MA 4D0YA 3D1MA 2VO9A 4MUQA 2PWNA 2J3RA 3N1OA 2J3WD 2WG3A 1R44A 4MUTA
chains in the Genus database with same CATH topology
1U10A 3N1GA 1R44A 2IBGE 3K7IB 4OAKA 2WFRA 2WFXA 5HNMA 4MURA 4OXDA 3K7JB 3N1QA 4OX5A 4MPHA 3MXWA 4OX3A 4MUSA 1LBUA 4NT9A 2WG4A 3N1RA 4JIDA 3N1PB 3M1NA 3N1MB 2WFQA 1TZPA 1VHHA 3K7HB 3K7GB 4C4NA 4F78A 3N1FA 4C4MA 4D0YA 3D1MA 2VO9A 4MUQA 3N1OA 2WG3A 3HO5H 4MUTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U10 A;  3N1G A;  1R44 A;  2IBG E;  3K7I B;  4OAK A;  2WFR A;  2WFX A;  5HNM A;  4MUR A;  4OXD A;  3K7J B;  3N1Q A;  4OX5 A;  4MPH A;  3MXW A;  4OX3 A;  4MUS A;  1LBU A;  4NT9 A;  2WG4 A;  3N1R A;  4JID A;  3N1P B;  3M1N A;  3N1M B;  2WFQ A;  1TZP A;  1VHH A;  3K7H B;  3K7G B;  4C4N A;  4F78 A;  3N1F A;  4C4M A;  4D0Y A;  3D1M A;  2VO9 A;  4MUQ A;  3N1O A;  2WG3 A;  3HO5 H;  4MUT A; 
#chains in the Genus database with same CATH topology
 1U10 A;  3N1G A;  4OAK A;  2IBG E;  2C0J A;  2CFH A;  3K7I B;  2J3W B;  2J3T B;  2BJN A;  2WFR A;  2WFX A;  5HNM A;  3KXC C;  2J3R B;  4MUR A;  4OXD A;  1WC9 A;  3K7J B;  3N1Q A;  4OX5 A;  4MPH A;  3MXW A;  4OX3 A;  2C0J B;  4MUS A;  1WC8 A;  1LBU A;  2OSO A;  4NT9 A;  2WG4 A;  3N1R A;  4JID A;  3KXC A;  3N1P B;  3M1N A;  2OSD A;  3CUE D;  3HO5 H;  3N1M B;  2WFQ A;  1TZP A;  1VHH A;  3K7H B;  3K7G B;  4C4N A;  3NJC A;  4F78 A;  3N1F A;  3CUE B;  2J3T A;  1SZ7 A;  2CFH C;  4C4M A;  4D0Y A;  3D1M A;  2VO9 A;  4MUQ A;  2PWN A;  2J3R A;  3N1O A;  2J3W D;  2WG3 A;  1R44 A;  4MUT A; 
#chains in the Genus database with same CATH homology
 1U10 A;  3N1G A;  1R44 A;  2IBG E;  3K7I B;  4OAK A;  2WFR A;  2WFX A;  5HNM A;  4MUR A;  4OXD A;  3K7J B;  3N1Q A;  4OX5 A;  4MPH A;  3MXW A;  4OX3 A;  4MUS A;  1LBU A;  4NT9 A;  2WG4 A;  3N1R A;  4JID A;  3N1P B;  3M1N A;  3N1M B;  2WFQ A;  1TZP A;  1VHH A;  3K7H B;  3K7G B;  4C4N A;  4F78 A;  3N1F A;  4C4M A;  4D0Y A;  3D1M A;  2VO9 A;  4MUQ A;  3N1O A;  2WG3 A;  3HO5 H;  4MUT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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