1VHHA

A potential catalytic site within the amino-terminal signalling domain of sonic hedgehog
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
157
structure length
157
Chain Sequence
KLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
pubmed doi rcsb
molecule tags Signalling protein
source organism Mus musculus
molecule keywords SONIC HEDGEHOG
total genus 45
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 1995-10-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 1vhhA00
4MUSA 2IBGE 3N1GA 4OX3A 4C4MA 4OAKA 3K7IB 4MUTA 4F78A 4C4NA 1R44A 2WG4A 4NT9A 3K7GB 3N1OA 1VHHA 2WG3A 3N1MB 2WFQA 4JIDA 2WFRA 1U10A 3N1FA 4OXDA 3MXWA 1LBUA 3N1QA 1TZPA 2WFXA 5HNMA 4MURA 2VO9A 3M1NA 3K7JB 3N1PB 4OX5A 4MPHA 4MUQA 3K7HB 3N1RA 3D1MA 3HO5H 4D0YA
chains in the Genus database with same CATH superfamily
4MUSA 2IBGE 2OSDA 3N1GA 4OX3A 4C4MA 4OAKA 2CFHC 3K7IB 4MUTA 2J3RA 4F78A 3CUED 1WC9A 4C4NA 4D0YA 1R44A 3KXCA 2J3WD 2WG4A 4NT9A 1SZ7A 3K7GB 3N1OA 1VHHA 2WG3A 3N1MB 2WFQA 3KXCC 4JIDA 2C0JB 2WFRA 1U10A 3N1FA 4OXDA 2BJNA 3MXWA 3NJCA 1WC8A 1LBUA 3N1QA 1TZPA 2WFXA 5HNMA 4MURA 2VO9A 3M1NA 3CUEB 2C0JA 2J3TB 2J3WB 3K7JB 3N1PB 4OX5A 4MPHA 2PWNA 2OSOA 4MUQA 2CFHA 3K7HB 2J3RB 3D1MA 3HO5H 2J3TA 3N1RA
chains in the Genus database with same CATH topology
4MUSA 2IBGE 3N1GA 4OX3A 4C4MA 4OAKA 3K7IB 4MUTA 4F78A 4C4NA 1R44A 2WG4A 4NT9A 3K7GB 3N1OA 1VHHA 2WG3A 3N1MB 2WFQA 4JIDA 2WFRA 1U10A 3N1FA 4OXDA 3MXWA 1LBUA 3N1QA 1TZPA 2WFXA 5HNMA 4MURA 2VO9A 3M1NA 3K7JB 3N1PB 4OX5A 4MPHA 4MUQA 3K7HB 3N1RA 3D1MA 3HO5H 4D0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MUS A;  2IBG E;  3N1G A;  4OX3 A;  4C4M A;  4OAK A;  3K7I B;  4MUT A;  4F78 A;  4C4N A;  1R44 A;  2WG4 A;  4NT9 A;  3K7G B;  3N1O A;  1VHH A;  2WG3 A;  3N1M B;  2WFQ A;  4JID A;  2WFR A;  1U10 A;  3N1F A;  4OXD A;  3MXW A;  1LBU A;  3N1Q A;  1TZP A;  2WFX A;  5HNM A;  4MUR A;  2VO9 A;  3M1N A;  3K7J B;  3N1P B;  4OX5 A;  4MPH A;  4MUQ A;  3K7H B;  3N1R A;  3D1M A;  3HO5 H;  4D0Y A; 
#chains in the Genus database with same CATH topology
 4MUS A;  2IBG E;  2OSD A;  3N1G A;  4OX3 A;  4C4M A;  4OAK A;  2CFH C;  3K7I B;  4MUT A;  2J3R A;  4F78 A;  3CUE D;  1WC9 A;  4C4N A;  4D0Y A;  1R44 A;  3KXC A;  2J3W D;  2WG4 A;  4NT9 A;  1SZ7 A;  3K7G B;  3N1O A;  1VHH A;  2WG3 A;  3N1M B;  2WFQ A;  3KXC C;  4JID A;  2C0J B;  2WFR A;  1U10 A;  3N1F A;  4OXD A;  2BJN A;  3MXW A;  3NJC A;  1WC8 A;  1LBU A;  3N1Q A;  1TZP A;  2WFX A;  5HNM A;  4MUR A;  2VO9 A;  3M1N A;  3CUE B;  2C0J A;  2J3T B;  2J3W B;  3K7J B;  3N1P B;  4OX5 A;  4MPH A;  2PWN A;  2OSO A;  4MUQ A;  2CFH A;  3K7H B;  2J3R B;  3D1M A;  3HO5 H;  2J3T A;  3N1R A; 
#chains in the Genus database with same CATH homology
 4MUS A;  2IBG E;  3N1G A;  4OX3 A;  4C4M A;  4OAK A;  3K7I B;  4MUT A;  4F78 A;  4C4N A;  1R44 A;  2WG4 A;  4NT9 A;  3K7G B;  3N1O A;  1VHH A;  2WG3 A;  3N1M B;  2WFQ A;  4JID A;  2WFR A;  1U10 A;  3N1F A;  4OXD A;  3MXW A;  1LBU A;  3N1Q A;  1TZP A;  2WFX A;  5HNM A;  4MUR A;  2VO9 A;  3M1N A;  3K7J B;  3N1P B;  4OX5 A;  4MPH A;  4MUQ A;  3K7H B;  3N1R A;  3D1M A;  3HO5 H;  4D0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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