1YIJR

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 36
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yijR00
1YITR 4WCEP 3CC7R 3G4SR 4V19W 1VQNR 2ZJRP 5DM6P 1VQ7R 3CXCQ 3CPWQ 5GADT 1K8AS 1JJ2Q 1M1KS 1VQ8R 1S72R 3CMER 1YJNR 5GAGT 3CCER 1Q82S 4WFAP 2ZJPP 1VQ6R 5MLCU 2ZJQP 3CCVR 3G71R 1KC8S 1W2BQ 5GAHT 3OW2Q 3CCQR 1VQMR 1K9MS 3CMAR 4WF9P 4IOCP 3CCMR 3CCRR 1KD1S 1QVFQ 3CC4R 1YJWR 1M90S 3CD6R 1VQPR 1YHQR 1KQSQ 4U67P 4IO9P 3G6ER 1Q86S 1Q81S 4IOAP 5DM7P 3PIOP 1Q7YS 1BXEA 4WFBP 1QVGQ 2OTJR 5JVGP 3J7YT 1YI2R 3CF5P 1VQKR 3PIPP 4UY8S 1N8RS 1I4JA 3J7ZS 5GAET 3CCSR 5JVHP 3CCJR 4WFNP 3CC2R 3DLLP 1YIJR 5HL7P 1VQLR 1YJ9R 3CCUR 1K73S 3I55R 1VQOR 2OTLR 3CCLR 2QEXR 3I56R 1NJIS 1VQ9R 2QA4R 1VQ5R 5H1SU 1VQ4R
chains in the Genus database with same CATH superfamily
1YITR 2C43A 4WCEP 3CC7R 3G4SR 4V19W 1VQNR 2ZJRP 5DM6P 1VQ7R 3CXCQ 3CPWQ 3HQJA 5GADT 4MRTA 1K8AS 1JJ2Q 2WDSA 1M1KS 2WASB 1VQ8R 4HC6A 1S72R 3CMER 3NE9A 1YJNR 3NE3B 5GAGT 3CCER 2JCAA 3NE1A 2WASA 3NFDA 1Q82S 4WFAP 2ZJPP 1VQ6R 2WDOA 5CMOA 1FTFA 5MLCU 2ZJQP 3CCVR 3G71R 1KC8S 1QR0A 1W2BQ 5GAHT 3OW2Q 2BYDA 3CCQR 1VQMR 1K9MS 3CMAR 4WF9P 4IOCP 4DXEA 3CCMR 3CCRR 1KD1S 1QVFQ 3CC4R 2WDYA 2D0PA 1YJWR 4JM7A 1M90S 2WATA 3HYKA 3CD6R 1VQPR 1YHQR 1KQSQ 2CG5A 4U67P 4IO9P 3G6ER 2D0OA 1Q86S 1Q81S 4IOAP 5DM7P 3PIOP 1Q7YS 3GWMA 1BXEA 4WFBP 2BDDA 1QVGQ 2OTJR 5JVGP 3J7YT 1NBWA 1YI2R 3CF5P 1VQKR 3PIPP 2QG8A 4UY8S 1N8RS 1I4JA 3J7ZS 5GAET 3CCSR 3H7QA 5JVHP 3QMNA 3CCJR 4WFNP 3CC2R 3DLLP 1YIJR 1F7TA 5HL7P 1VQLR 1YJ9R 3CCUR 1K73S 1F80A 3I55R 1VQOR 2OTLR 1FTEA 3CCLR 2QEXR 3I56R 1NJIS 1VQ9R 2QA4R 1VQ5R 5CXDA 5H1SU 1F7LA 2JBZA 1VQ4R 1FTHA
chains in the Genus database with same CATH topology
1YITR 4WCEP 3CC7R 3G4SR 4V19W 1VQNR 2ZJRP 5DM6P 1VQ7R 3CXCQ 3CPWQ 5GADT 1K8AS 1JJ2Q 1M1KS 1VQ8R 1S72R 3CMER 1YJNR 5GAGT 3CCER 1Q82S 4WFAP 2ZJPP 1VQ6R 5MLCU 2ZJQP 3CCVR 3G71R 1KC8S 1W2BQ 5GAHT 3OW2Q 3CCQR 1VQMR 1K9MS 3CMAR 4WF9P 4IOCP 3CCMR 3CCRR 1KD1S 1QVFQ 3CC4R 1YJWR 1M90S 3CD6R 1VQPR 1YHQR 1KQSQ 4U67P 4IO9P 3G6ER 1Q86S 1Q81S 4IOAP 5DM7P 3PIOP 1Q7YS 1BXEA 4WFBP 1QVGQ 2OTJR 5JVGP 3J7YT 1YI2R 3CF5P 1VQKR 3PIPP 4UY8S 1N8RS 1I4JA 3J7ZS 5GAET 3CCSR 5JVHP 3CCJR 4WFNP 3CC2R 3DLLP 1YIJR 5HL7P 1VQLR 1YJ9R 3CCUR 1K73S 3I55R 1VQOR 2OTLR 3CCLR 2QEXR 3I56R 1NJIS 1VQ9R 2QA4R 1VQ5R 5H1SU 1VQ4R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YIT R;  4WCE P;  3CC7 R;  3G4S R;  4V19 W;  1VQN R;  2ZJR P;  5DM6 P;  1VQ7 R;  3CXC Q;  3CPW Q;  5GAD T;  1K8A S;  1JJ2 Q;  1M1K S;  1VQ8 R;  1S72 R;  3CME R;  1YJN R;  5GAG T;  3CCE R;  1Q82 S;  4WFA P;  2ZJP P;  1VQ6 R;  5MLC U;  2ZJQ P;  3CCV R;  3G71 R;  1KC8 S;  1W2B Q;  5GAH T;  3OW2 Q;  3CCQ R;  1VQM R;  1K9M S;  3CMA R;  4WF9 P;  4IOC P;  3CCM R;  3CCR R;  1KD1 S;  1QVF Q;  3CC4 R;  1YJW R;  1M90 S;  3CD6 R;  1VQP R;  1YHQ R;  1KQS Q;  4U67 P;  4IO9 P;  3G6E R;  1Q86 S;  1Q81 S;  4IOA P;  5DM7 P;  3PIO P;  1Q7Y S;  1BXE A;  4WFB P;  1QVG Q;  2OTJ R;  5JVG P;  3J7Y T;  1YI2 R;  3CF5 P;  1VQK R;  3PIP P;  4UY8 S;  1N8R S;  1I4J A;  3J7Z S;  5GAE T;  3CCS R;  5JVH P;  3CCJ R;  4WFN P;  3CC2 R;  3DLL P;  1YIJ R;  5HL7 P;  1VQL R;  1YJ9 R;  3CCU R;  1K73 S;  3I55 R;  1VQO R;  2OTL R;  3CCL R;  2QEX R;  3I56 R;  1NJI S;  1VQ9 R;  2QA4 R;  1VQ5 R;  5H1S U;  1VQ4 R; 
#chains in the Genus database with same CATH topology
 1YIT R;  2C43 A;  4WCE P;  3CC7 R;  3G4S R;  4V19 W;  1VQN R;  2ZJR P;  5DM6 P;  1VQ7 R;  3CXC Q;  3CPW Q;  3HQJ A;  5GAD T;  4MRT A;  1K8A S;  1JJ2 Q;  2WDS A;  1M1K S;  2WAS B;  1VQ8 R;  4HC6 A;  1S72 R;  3CME R;  3NE9 A;  1YJN R;  3NE3 B;  5GAG T;  3CCE R;  2JCA A;  3NE1 A;  2WAS A;  3NFD A;  1Q82 S;  4WFA P;  2ZJP P;  1VQ6 R;  2WDO A;  5CMO A;  1FTF A;  5MLC U;  2ZJQ P;  3CCV R;  3G71 R;  1KC8 S;  1QR0 A;  1W2B Q;  5GAH T;  3OW2 Q;  2BYD A;  3CCQ R;  1VQM R;  1K9M S;  3CMA R;  4WF9 P;  4IOC P;  4DXE A;  3CCM R;  3CCR R;  1KD1 S;  1QVF Q;  3CC4 R;  2WDY A;  2D0P A;  1YJW R;  4JM7 A;  1M90 S;  2WAT A;  3HYK A;  3CD6 R;  1VQP R;  1YHQ R;  1KQS Q;  2CG5 A;  4U67 P;  4IO9 P;  3G6E R;  2D0O A;  1Q86 S;  1Q81 S;  4IOA P;  5DM7 P;  3PIO P;  1Q7Y S;  3GWM A;  1BXE A;  4WFB P;  2BDD A;  1QVG Q;  2OTJ R;  5JVG P;  3J7Y T;  1NBW A;  1YI2 R;  3CF5 P;  1VQK R;  3PIP P;  2QG8 A;  4UY8 S;  1N8R S;  1I4J A;  3J7Z S;  5GAE T;  3CCS R;  3H7Q A;  5JVH P;  3QMN A;  3CCJ R;  4WFN P;  3CC2 R;  3DLL P;  1YIJ R;  1F7T A;  5HL7 P;  1VQL R;  1YJ9 R;  3CCU R;  1K73 S;  1F80 A;  3I55 R;  1VQO R;  2OTL R;  1FTE A;  3CCL R;  2QEX R;  3I56 R;  1NJI S;  1VQ9 R;  2QA4 R;  1VQ5 R;  5CXD A;  5H1S U;  1F7L A;  2JBZ A;  1VQ4 R;  1FTH A; 
#chains in the Genus database with same CATH homology
 1YIT R;  4WCE P;  3CC7 R;  3G4S R;  4V19 W;  1VQN R;  2ZJR P;  5DM6 P;  1VQ7 R;  3CXC Q;  3CPW Q;  5GAD T;  1K8A S;  1JJ2 Q;  1M1K S;  1VQ8 R;  1S72 R;  3CME R;  1YJN R;  5GAG T;  3CCE R;  1Q82 S;  4WFA P;  2ZJP P;  1VQ6 R;  5MLC U;  2ZJQ P;  3CCV R;  3G71 R;  1KC8 S;  1W2B Q;  5GAH T;  3OW2 Q;  3CCQ R;  1VQM R;  1K9M S;  3CMA R;  4WF9 P;  4IOC P;  3CCM R;  3CCR R;  1KD1 S;  1QVF Q;  3CC4 R;  1YJW R;  1M90 S;  3CD6 R;  1VQP R;  1YHQ R;  1KQS Q;  4U67 P;  4IO9 P;  3G6E R;  1Q86 S;  1Q81 S;  4IOA P;  5DM7 P;  3PIO P;  1Q7Y S;  1BXE A;  4WFB P;  1QVG Q;  2OTJ R;  5JVG P;  3J7Y T;  1YI2 R;  3CF5 P;  1VQK R;  3PIP P;  4UY8 S;  1N8R S;  1I4J A;  3J7Z S;  5GAE T;  3CCS R;  5JVH P;  3CCJ R;  4WFN P;  3CC2 R;  3DLL P;  1YIJ R;  5HL7 P;  1VQL R;  1YJ9 R;  3CCU R;  1K73 S;  3I55 R;  1VQO R;  2OTL R;  3CCL R;  2QEX R;  3I56 R;  1NJI S;  1VQ9 R;  2QA4 R;  1VQ5 R;  5H1S U;  1VQ4 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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