1YITR

Crystal structure of virginiamycin m and s bound to the 50s ribosomal subunit of haloarcula marismortui
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 35
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yitR00
2ZJPP 1KQSQ 1YHQR 5MLCU 1YIJR 4V19W 3CMER 2QEXR 3CPWQ 1M1KS 3I55R 1VQ8R 1W2BQ 1YJNR 3G6ER 1VQ4R 1QVFQ 3CCER 1KC8S 1N8RS 3OW2Q 1QVGQ 3CF5P 2ZJQP 2OTJR 5DM7P 1VQ6R 1VQKR 4IOAP 3CC4R 3CCMR 3J7ZS 3CC2R 1YJWR 4WFAP 3PIOP 4UY8S 1VQMR 1Q81S 1Q86S 5GAHT 1Q7YS 5JVHP 1VQ5R 2QA4R 1VQ7R 1BXEA 3CCLR 5JVGP 1S72R 3DLLP 5H1SU 1NJIS 1VQNR 1Q82S 5GAET 1M90S 4IO9P 4WF9P 2OTLR 3CCVR 5GAGT 1KD1S 1JJ2Q 1YJ9R 3G4SR 4IOCP 3CCSR 1I4JA 5GADT 3J7YT 3CCQR 3I56R 4WCEP 1YI2R 1VQ9R 5HL7P 3CCUR 1K8AS 3CMAR 1YITR 2ZJRP 3PIPP 1K73S 3CXCQ 1VQPR 1VQLR 3G71R 1K9MS 4WFNP 4U67P 3CD6R 3CCJR 4WFBP 3CCRR 1VQOR 5DM6P 3CC7R
chains in the Genus database with same CATH superfamily
2ZJPP 1KQSQ 1YHQR 1F80A 5MLCU 3GWMA 1YIJR 4V19W 3CMER 3H7QA 2QEXR 3CPWQ 2WASB 1M1KS 3I55R 1VQ8R 1W2BQ 1YJNR 3G6ER 1VQ4R 1QVFQ 2BYDA 3CCER 1KC8S 1N8RS 3OW2Q 1QVGQ 3CF5P 2ZJQP 2OTJR 5DM7P 3HYKA 1VQ6R 4HC6A 1VQKR 4IOAP 3CC4R 3NE1A 3CCMR 1QR0A 1F7LA 3J7ZS 3CC2R 1YJWR 4WFAP 3QMNA 2JCAA 3PIOP 4UY8S 1VQMR 1Q81S 1Q86S 5GAHT 3NE9A 1Q7YS 5JVHP 4MRTA 1VQ5R 2QA4R 1VQ7R 1BXEA 3CCLR 5JVGP 1S72R 4DXEA 3DLLP 5H1SU 1FTEA 1NJIS 1VQNR 1Q82S 5GAET 1M90S 2WDSA 4IO9P 4WF9P 2OTLR 3CCVR 5GAGT 5CMOA 1KD1S 2WDOA 1JJ2Q 1YJ9R 3G4SR 4IOCP 3CCSR 4JM7A 3HQJA 1I4JA 2D0OA 5GADT 3NFDA 1F7TA 3J7YT 2WDYA 1NBWA 3CCQR 1FTHA 3I56R 4WCEP 2QG8A 1YI2R 1VQ9R 5HL7P 2CG5A 1FTFA 2C43A 3CCUR 1K8AS 3CMAR 1YITR 2WASA 2BDDA 2ZJRP 3PIPP 2WATA 1K73S 3CXCQ 1VQPR 1VQLR 3G71R 2D0PA 1K9MS 4WFNP 4U67P 3CD6R 5CXDA 3CCJR 4WFBP 3CCRR 2JBZA 1VQOR 5DM6P 3CC7R 3NE3B
chains in the Genus database with same CATH topology
2ZJPP 1KQSQ 1YHQR 5MLCU 1YIJR 4V19W 3CMER 2QEXR 3CPWQ 1M1KS 3I55R 1VQ8R 1W2BQ 1YJNR 3G6ER 1VQ4R 1QVFQ 3CCER 1KC8S 1N8RS 3OW2Q 1QVGQ 3CF5P 2ZJQP 2OTJR 5DM7P 1VQ6R 1VQKR 4IOAP 3CC4R 3CCMR 3J7ZS 3CC2R 1YJWR 4WFAP 3PIOP 4UY8S 1VQMR 1Q81S 1Q86S 5GAHT 1Q7YS 5JVHP 1VQ5R 2QA4R 1VQ7R 1BXEA 3CCLR 5JVGP 1S72R 3DLLP 5H1SU 1NJIS 1VQNR 1Q82S 5GAET 1M90S 4IO9P 4WF9P 2OTLR 3CCVR 5GAGT 1KD1S 1JJ2Q 1YJ9R 3G4SR 4IOCP 3CCSR 1I4JA 5GADT 3J7YT 3CCQR 3I56R 4WCEP 1YI2R 1VQ9R 5HL7P 3CCUR 1K8AS 3CMAR 1YITR 2ZJRP 3PIPP 1K73S 3CXCQ 1VQPR 1VQLR 3G71R 1K9MS 4WFNP 4U67P 3CD6R 3CCJR 4WFBP 3CCRR 1VQOR 5DM6P 3CC7R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJP P;  1KQS Q;  1YHQ R;  5MLC U;  1YIJ R;  4V19 W;  3CME R;  2QEX R;  3CPW Q;  1M1K S;  3I55 R;  1VQ8 R;  1W2B Q;  1YJN R;  3G6E R;  1VQ4 R;  1QVF Q;  3CCE R;  1KC8 S;  1N8R S;  3OW2 Q;  1QVG Q;  3CF5 P;  2ZJQ P;  2OTJ R;  5DM7 P;  1VQ6 R;  1VQK R;  4IOA P;  3CC4 R;  3CCM R;  3J7Z S;  3CC2 R;  1YJW R;  4WFA P;  3PIO P;  4UY8 S;  1VQM R;  1Q81 S;  1Q86 S;  5GAH T;  1Q7Y S;  5JVH P;  1VQ5 R;  2QA4 R;  1VQ7 R;  1BXE A;  3CCL R;  5JVG P;  1S72 R;  3DLL P;  5H1S U;  1NJI S;  1VQN R;  1Q82 S;  5GAE T;  1M90 S;  4IO9 P;  4WF9 P;  2OTL R;  3CCV R;  5GAG T;  1KD1 S;  1JJ2 Q;  1YJ9 R;  3G4S R;  4IOC P;  3CCS R;  1I4J A;  5GAD T;  3J7Y T;  3CCQ R;  3I56 R;  4WCE P;  1YI2 R;  1VQ9 R;  5HL7 P;  3CCU R;  1K8A S;  3CMA R;  1YIT R;  2ZJR P;  3PIP P;  1K73 S;  3CXC Q;  1VQP R;  1VQL R;  3G71 R;  1K9M S;  4WFN P;  4U67 P;  3CD6 R;  3CCJ R;  4WFB P;  3CCR R;  1VQO R;  5DM6 P;  3CC7 R; 
#chains in the Genus database with same CATH topology
 2ZJP P;  1KQS Q;  1YHQ R;  1F80 A;  5MLC U;  3GWM A;  1YIJ R;  4V19 W;  3CME R;  3H7Q A;  2QEX R;  3CPW Q;  2WAS B;  1M1K S;  3I55 R;  1VQ8 R;  1W2B Q;  1YJN R;  3G6E R;  1VQ4 R;  1QVF Q;  2BYD A;  3CCE R;  1KC8 S;  1N8R S;  3OW2 Q;  1QVG Q;  3CF5 P;  2ZJQ P;  2OTJ R;  5DM7 P;  3HYK A;  1VQ6 R;  4HC6 A;  1VQK R;  4IOA P;  3CC4 R;  3NE1 A;  3CCM R;  1QR0 A;  1F7L A;  3J7Z S;  3CC2 R;  1YJW R;  4WFA P;  3QMN A;  2JCA A;  3PIO P;  4UY8 S;  1VQM R;  1Q81 S;  1Q86 S;  5GAH T;  3NE9 A;  1Q7Y S;  5JVH P;  4MRT A;  1VQ5 R;  2QA4 R;  1VQ7 R;  1BXE A;  3CCL R;  5JVG P;  1S72 R;  4DXE A;  3DLL P;  5H1S U;  1FTE A;  1NJI S;  1VQN R;  1Q82 S;  5GAE T;  1M90 S;  2WDS A;  4IO9 P;  4WF9 P;  2OTL R;  3CCV R;  5GAG T;  5CMO A;  1KD1 S;  2WDO A;  1JJ2 Q;  1YJ9 R;  3G4S R;  4IOC P;  3CCS R;  4JM7 A;  3HQJ A;  1I4J A;  2D0O A;  5GAD T;  3NFD A;  1F7T A;  3J7Y T;  2WDY A;  1NBW A;  3CCQ R;  1FTH A;  3I56 R;  4WCE P;  2QG8 A;  1YI2 R;  1VQ9 R;  5HL7 P;  2CG5 A;  1FTF A;  2C43 A;  3CCU R;  1K8A S;  3CMA R;  1YIT R;  2WAS A;  2BDD A;  2ZJR P;  3PIP P;  2WAT A;  1K73 S;  3CXC Q;  1VQP R;  1VQL R;  3G71 R;  2D0P A;  1K9M S;  4WFN P;  4U67 P;  3CD6 R;  5CXD A;  3CCJ R;  4WFB P;  3CCR R;  2JBZ A;  1VQO R;  5DM6 P;  3CC7 R;  3NE3 B; 
#chains in the Genus database with same CATH homology
 2ZJP P;  1KQS Q;  1YHQ R;  5MLC U;  1YIJ R;  4V19 W;  3CME R;  2QEX R;  3CPW Q;  1M1K S;  3I55 R;  1VQ8 R;  1W2B Q;  1YJN R;  3G6E R;  1VQ4 R;  1QVF Q;  3CCE R;  1KC8 S;  1N8R S;  3OW2 Q;  1QVG Q;  3CF5 P;  2ZJQ P;  2OTJ R;  5DM7 P;  1VQ6 R;  1VQK R;  4IOA P;  3CC4 R;  3CCM R;  3J7Z S;  3CC2 R;  1YJW R;  4WFA P;  3PIO P;  4UY8 S;  1VQM R;  1Q81 S;  1Q86 S;  5GAH T;  1Q7Y S;  5JVH P;  1VQ5 R;  2QA4 R;  1VQ7 R;  1BXE A;  3CCL R;  5JVG P;  1S72 R;  3DLL P;  5H1S U;  1NJI S;  1VQN R;  1Q82 S;  5GAE T;  1M90 S;  4IO9 P;  4WF9 P;  2OTL R;  3CCV R;  5GAG T;  1KD1 S;  1JJ2 Q;  1YJ9 R;  3G4S R;  4IOC P;  3CCS R;  1I4J A;  5GAD T;  3J7Y T;  3CCQ R;  3I56 R;  4WCE P;  1YI2 R;  1VQ9 R;  5HL7 P;  3CCU R;  1K8A S;  3CMA R;  1YIT R;  2ZJR P;  3PIP P;  1K73 S;  3CXC Q;  1VQP R;  1VQL R;  3G71 R;  1K9M S;  4WFN P;  4U67 P;  3CD6 R;  3CCJ R;  4WFB P;  3CCR R;  1VQO R;  5DM6 P;  3CC7 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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