1YJWR

Crystal structure of quinupristin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 38
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yjwR00
1VQPR 1KC8S 5JVHP 3J7YT 2ZJQP 1VQLR 3CC4R 1K9MS 2QEXR 1VQ7R 4U67P 1Q7YS 3CCQR 3CCSR 3OW2Q 1K73S 4WFBP 3J7ZS 1Q82S 3CD6R 5MLCU 1VQKR 4IO9P 3CCVR 3CMAR 3CC2R 1NJIS 3CF5P 3CCUR 5GADT 4UY8S 2ZJRP 1I4JA 1M90S 1S72R 5GAET 3CCMR 1VQOR 5GAHT 2ZJPP 3I56R 3DLLP 1YJNR 3G4SR 1VQ9R 1KQSQ 4IOCP 2QA4R 1YJ9R 3CCER 3G71R 1YJWR 4WF9P 5DM7P 1BXEA 3CCRR 2OTLR 1Q86S 1VQ4R 3PIOP 1YHQR 1YITR 3I55R 1JJ2Q 5JVGP 1VQMR 3CCJR 1KD1S 1VQ8R 1VQ6R 1N8RS 5HL7P 1QVGQ 2OTJR 4WFAP 3CMER 4IOAP 4V19W 3CPWQ 1K8AS 1YIJR 3CXCQ 4WFNP 5DM6P 4WCEP 1M1KS 1VQNR 5GAGT 3CC7R 1QVFQ 5H1SU 1Q81S 1VQ5R 1W2BQ 1YI2R 3CCLR 3G6ER 3PIPP
chains in the Genus database with same CATH superfamily
2JBZA 1VQPR 5CXDA 1KC8S 5JVHP 3J7YT 2ZJQP 1QR0A 4MRTA 1VQLR 3CC4R 1K9MS 2QEXR 2WDOA 1VQ7R 4U67P 1Q7YS 3CCQR 3CCSR 2WDSA 3OW2Q 3NE3B 3QMNA 1K73S 4WFBP 3J7ZS 1Q82S 2QG8A 3CD6R 5MLCU 4DXEA 1F7TA 1VQKR 4IO9P 3CCVR 3CMAR 3CC2R 3H7QA 1NJIS 3CF5P 3CCUR 5GADT 2WASB 2D0PA 4UY8S 2ZJRP 1I4JA 1F7LA 1M90S 3GWMA 1S72R 5GAET 1FTEA 3CCMR 1VQOR 5GAHT 2ZJPP 3I56R 4HC6A 3DLLP 1YJNR 3G4SR 1VQ9R 1KQSQ 4IOCP 2QA4R 1F80A 5CMOA 1YJ9R 3NFDA 3CCER 3G71R 3NE1A 1YJWR 2BDDA 4WF9P 2CG5A 2WDYA 5DM7P 1FTFA 1BXEA 3CCRR 2BYDA 2OTLR 4JM7A 1Q86S 1VQ4R 3HYKA 3PIOP 1YHQR 1YITR 2C43A 3I55R 1JJ2Q 5JVGP 1VQMR 1NBWA 3CCJR 2D0OA 1KD1S 1VQ8R 1VQ6R 1N8RS 5HL7P 1QVGQ 3HQJA 2OTJR 4WFAP 3CMER 2WATA 1FTHA 4IOAP 4V19W 3CPWQ 1K8AS 1YIJR 3CXCQ 4WFNP 5DM6P 4WCEP 2JCAA 1M1KS 1VQNR 5GAGT 3NE9A 2WASA 3CC7R 1QVFQ 5H1SU 1Q81S 1VQ5R 1W2BQ 1YI2R 3CCLR 3G6ER 3PIPP
chains in the Genus database with same CATH topology
1VQPR 1KC8S 5JVHP 3J7YT 2ZJQP 1VQLR 3CC4R 1K9MS 2QEXR 1VQ7R 4U67P 1Q7YS 3CCQR 3CCSR 3OW2Q 1K73S 4WFBP 3J7ZS 1Q82S 3CD6R 5MLCU 1VQKR 4IO9P 3CCVR 3CMAR 3CC2R 1NJIS 3CF5P 3CCUR 5GADT 4UY8S 2ZJRP 1I4JA 1M90S 1S72R 5GAET 3CCMR 1VQOR 5GAHT 2ZJPP 3I56R 3DLLP 1YJNR 3G4SR 1VQ9R 1KQSQ 4IOCP 2QA4R 1YJ9R 3CCER 3G71R 1YJWR 4WF9P 5DM7P 1BXEA 3CCRR 2OTLR 1Q86S 1VQ4R 3PIOP 1YHQR 1YITR 3I55R 1JJ2Q 5JVGP 1VQMR 3CCJR 1KD1S 1VQ8R 1VQ6R 1N8RS 5HL7P 1QVGQ 2OTJR 4WFAP 3CMER 4IOAP 4V19W 3CPWQ 1K8AS 1YIJR 3CXCQ 4WFNP 5DM6P 4WCEP 1M1KS 1VQNR 5GAGT 3CC7R 1QVFQ 5H1SU 1Q81S 1VQ5R 1W2BQ 1YI2R 3CCLR 3G6ER 3PIPP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQP R;  1KC8 S;  5JVH P;  3J7Y T;  2ZJQ P;  1VQL R;  3CC4 R;  1K9M S;  2QEX R;  1VQ7 R;  4U67 P;  1Q7Y S;  3CCQ R;  3CCS R;  3OW2 Q;  1K73 S;  4WFB P;  3J7Z S;  1Q82 S;  3CD6 R;  5MLC U;  1VQK R;  4IO9 P;  3CCV R;  3CMA R;  3CC2 R;  1NJI S;  3CF5 P;  3CCU R;  5GAD T;  4UY8 S;  2ZJR P;  1I4J A;  1M90 S;  1S72 R;  5GAE T;  3CCM R;  1VQO R;  5GAH T;  2ZJP P;  3I56 R;  3DLL P;  1YJN R;  3G4S R;  1VQ9 R;  1KQS Q;  4IOC P;  2QA4 R;  1YJ9 R;  3CCE R;  3G71 R;  1YJW R;  4WF9 P;  5DM7 P;  1BXE A;  3CCR R;  2OTL R;  1Q86 S;  1VQ4 R;  3PIO P;  1YHQ R;  1YIT R;  3I55 R;  1JJ2 Q;  5JVG P;  1VQM R;  3CCJ R;  1KD1 S;  1VQ8 R;  1VQ6 R;  1N8R S;  5HL7 P;  1QVG Q;  2OTJ R;  4WFA P;  3CME R;  4IOA P;  4V19 W;  3CPW Q;  1K8A S;  1YIJ R;  3CXC Q;  4WFN P;  5DM6 P;  4WCE P;  1M1K S;  1VQN R;  5GAG T;  3CC7 R;  1QVF Q;  5H1S U;  1Q81 S;  1VQ5 R;  1W2B Q;  1YI2 R;  3CCL R;  3G6E R;  3PIP P; 
#chains in the Genus database with same CATH topology
 2JBZ A;  1VQP R;  5CXD A;  1KC8 S;  5JVH P;  3J7Y T;  2ZJQ P;  1QR0 A;  4MRT A;  1VQL R;  3CC4 R;  1K9M S;  2QEX R;  2WDO A;  1VQ7 R;  4U67 P;  1Q7Y S;  3CCQ R;  3CCS R;  2WDS A;  3OW2 Q;  3NE3 B;  3QMN A;  1K73 S;  4WFB P;  3J7Z S;  1Q82 S;  2QG8 A;  3CD6 R;  5MLC U;  4DXE A;  1F7T A;  1VQK R;  4IO9 P;  3CCV R;  3CMA R;  3CC2 R;  3H7Q A;  1NJI S;  3CF5 P;  3CCU R;  5GAD T;  2WAS B;  2D0P A;  4UY8 S;  2ZJR P;  1I4J A;  1F7L A;  1M90 S;  3GWM A;  1S72 R;  5GAE T;  1FTE A;  3CCM R;  1VQO R;  5GAH T;  2ZJP P;  3I56 R;  4HC6 A;  3DLL P;  1YJN R;  3G4S R;  1VQ9 R;  1KQS Q;  4IOC P;  2QA4 R;  1F80 A;  5CMO A;  1YJ9 R;  3NFD A;  3CCE R;  3G71 R;  3NE1 A;  1YJW R;  2BDD A;  4WF9 P;  2CG5 A;  2WDY A;  5DM7 P;  1FTF A;  1BXE A;  3CCR R;  2BYD A;  2OTL R;  4JM7 A;  1Q86 S;  1VQ4 R;  3HYK A;  3PIO P;  1YHQ R;  1YIT R;  2C43 A;  3I55 R;  1JJ2 Q;  5JVG P;  1VQM R;  1NBW A;  3CCJ R;  2D0O A;  1KD1 S;  1VQ8 R;  1VQ6 R;  1N8R S;  5HL7 P;  1QVG Q;  3HQJ A;  2OTJ R;  4WFA P;  3CME R;  2WAT A;  1FTH A;  4IOA P;  4V19 W;  3CPW Q;  1K8A S;  1YIJ R;  3CXC Q;  4WFN P;  5DM6 P;  4WCE P;  2JCA A;  1M1K S;  1VQN R;  5GAG T;  3NE9 A;  2WAS A;  3CC7 R;  1QVF Q;  5H1S U;  1Q81 S;  1VQ5 R;  1W2B Q;  1YI2 R;  3CCL R;  3G6E R;  3PIP P; 
#chains in the Genus database with same CATH homology
 1VQP R;  1KC8 S;  5JVH P;  3J7Y T;  2ZJQ P;  1VQL R;  3CC4 R;  1K9M S;  2QEX R;  1VQ7 R;  4U67 P;  1Q7Y S;  3CCQ R;  3CCS R;  3OW2 Q;  1K73 S;  4WFB P;  3J7Z S;  1Q82 S;  3CD6 R;  5MLC U;  1VQK R;  4IO9 P;  3CCV R;  3CMA R;  3CC2 R;  1NJI S;  3CF5 P;  3CCU R;  5GAD T;  4UY8 S;  2ZJR P;  1I4J A;  1M90 S;  1S72 R;  5GAE T;  3CCM R;  1VQO R;  5GAH T;  2ZJP P;  3I56 R;  3DLL P;  1YJN R;  3G4S R;  1VQ9 R;  1KQS Q;  4IOC P;  2QA4 R;  1YJ9 R;  3CCE R;  3G71 R;  1YJW R;  4WF9 P;  5DM7 P;  1BXE A;  3CCR R;  2OTL R;  1Q86 S;  1VQ4 R;  3PIO P;  1YHQ R;  1YIT R;  3I55 R;  1JJ2 Q;  5JVG P;  1VQM R;  3CCJ R;  1KD1 S;  1VQ8 R;  1VQ6 R;  1N8R S;  5HL7 P;  1QVG Q;  2OTJ R;  4WFA P;  3CME R;  4IOA P;  4V19 W;  3CPW Q;  1K8A S;  1YIJ R;  3CXC Q;  4WFN P;  5DM6 P;  4WCE P;  1M1K S;  1VQN R;  5GAG T;  3CC7 R;  1QVF Q;  5H1S U;  1Q81 S;  1VQ5 R;  1W2B Q;  1YI2 R;  3CCL R;  3G6E R;  3PIP P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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