1K8AS

Co-crystal structure of carbomycin a bound to the 50s ribosomal subunit of haloarcula marismortui
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structures of four macrolide antibiotics bound to the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RRNA
total genus 36
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2001-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1k8aS00
3PIPP 4UY8S 1VQPR 4U67P 3CC2R 5GAGT 3CXCQ 1Q81S 5GAET 4IO9P 2ZJRP 3CCRR 1YJ9R 5JVGP 1VQ7R 2QA4R 1YITR 4IOAP 5H1SU 5DM7P 4WFAP 1K8AS 2OTJR 3DLLP 3G4SR 1BXEA 1QVGQ 1VQOR 1VQ8R 2ZJQP 1S72R 1YIJR 1VQNR 3I55R 5GADT 3CCJR 3CCSR 4IOCP 2QEXR 3CCQR 1K73S 5GAHT 5JVHP 2OTLR 2ZJPP 1KQSQ 4WCEP 1I4JA 1KD1S 1VQ6R 1VQ5R 1YJNR 1Q7YS 1VQ4R 3G6ER 4WFNP 1M1KS 1QVFQ 5DM6P 1W2BQ 3CC7R 4V19W 4WF9P 1N8RS 1VQMR 3J7ZS 3CCVR 1KC8S 1K9MS 1JJ2Q 1VQ9R 3PIOP 5MLCU 3G71R 3CC4R 3CMAR 5HL7P 1Q82S 4WFBP 3I56R 3J7YT 1VQKR 1VQLR 3CCMR 3CD6R 3CMER 3CPWQ 1YI2R 1YHQR 1M90S 1NJIS 3CCUR 3CCLR 3CF5P 3CCER 3OW2Q 1YJWR 1Q86S
chains in the Genus database with same CATH superfamily
2C43A 3PIPP 4UY8S 1VQPR 4U67P 3CC2R 5GAGT 3CXCQ 4DXEA 1Q81S 5GAET 3QMNA 4IO9P 2ZJRP 3CCRR 1YJ9R 5JVGP 2WDSA 1F80A 1VQ7R 3NFDA 2WDOA 2D0PA 2QA4R 1YITR 2WASA 4IOAP 3HQJA 5H1SU 5DM7P 4WFAP 1K8AS 2OTJR 3DLLP 3G4SR 1BXEA 1QVGQ 1VQOR 1VQ8R 1FTHA 2BDDA 2ZJQP 1S72R 1YIJR 1VQNR 3I55R 5GADT 1NBWA 3CCJR 3CCSR 4IOCP 2QEXR 3CCQR 1K73S 5GAHT 5JVHP 2OTLR 5CXDA 2ZJPP 1KQSQ 3NE3B 2WATA 4WCEP 1I4JA 4HC6A 2QG8A 1KD1S 1FTFA 1VQ6R 1VQ5R 1YJNR 1Q7YS 1VQ4R 3NE9A 3H7QA 3G6ER 2JCAA 4WFNP 1M1KS 1QVFQ 5DM6P 3HYKA 1W2BQ 3CC7R 4V19W 4WF9P 1N8RS 1VQMR 3J7ZS 3CCVR 1KC8S 1K9MS 1F7LA 1JJ2Q 3NE1A 2BYDA 2CG5A 1VQ9R 5CMOA 5MLCU 3PIOP 3G71R 3CC4R 2JBZA 2WASB 3CMAR 5HL7P 4MRTA 2D0OA 3GWMA 4JM7A 1Q82S 4WFBP 3I56R 2WDYA 3J7YT 1VQKR 1QR0A 1VQLR 3CCMR 3CD6R 3CMER 3CPWQ 1YI2R 1YHQR 1F7TA 1M90S 1NJIS 3CCUR 3CCLR 3CF5P 3CCER 1FTEA 3OW2Q 1YJWR 1Q86S
chains in the Genus database with same CATH topology
3PIPP 4UY8S 1VQPR 4U67P 3CC2R 5GAGT 3CXCQ 1Q81S 5GAET 4IO9P 2ZJRP 3CCRR 1YJ9R 5JVGP 1VQ7R 2QA4R 1YITR 4IOAP 5H1SU 5DM7P 4WFAP 1K8AS 2OTJR 3DLLP 3G4SR 1BXEA 1QVGQ 1VQOR 1VQ8R 2ZJQP 1S72R 1YIJR 1VQNR 3I55R 5GADT 3CCJR 3CCSR 4IOCP 2QEXR 3CCQR 1K73S 5GAHT 5JVHP 2OTLR 2ZJPP 1KQSQ 4WCEP 1I4JA 1KD1S 1VQ6R 1VQ5R 1YJNR 1Q7YS 1VQ4R 3G6ER 4WFNP 1M1KS 1QVFQ 5DM6P 1W2BQ 3CC7R 4V19W 4WF9P 1N8RS 1VQMR 3J7ZS 3CCVR 1KC8S 1K9MS 1JJ2Q 1VQ9R 3PIOP 5MLCU 3G71R 3CC4R 3CMAR 5HL7P 1Q82S 4WFBP 3I56R 3J7YT 1VQKR 1VQLR 3CCMR 3CD6R 3CMER 3CPWQ 1YI2R 1YHQR 1M90S 1NJIS 3CCUR 3CCLR 3CF5P 3CCER 3OW2Q 1YJWR 1Q86S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIP P;  4UY8 S;  1VQP R;  4U67 P;  3CC2 R;  5GAG T;  3CXC Q;  1Q81 S;  5GAE T;  4IO9 P;  2ZJR P;  3CCR R;  1YJ9 R;  5JVG P;  1VQ7 R;  2QA4 R;  1YIT R;  4IOA P;  5H1S U;  5DM7 P;  4WFA P;  1K8A S;  2OTJ R;  3DLL P;  3G4S R;  1BXE A;  1QVG Q;  1VQO R;  1VQ8 R;  2ZJQ P;  1S72 R;  1YIJ R;  1VQN R;  3I55 R;  5GAD T;  3CCJ R;  3CCS R;  4IOC P;  2QEX R;  3CCQ R;  1K73 S;  5GAH T;  5JVH P;  2OTL R;  2ZJP P;  1KQS Q;  4WCE P;  1I4J A;  1KD1 S;  1VQ6 R;  1VQ5 R;  1YJN R;  1Q7Y S;  1VQ4 R;  3G6E R;  4WFN P;  1M1K S;  1QVF Q;  5DM6 P;  1W2B Q;  3CC7 R;  4V19 W;  4WF9 P;  1N8R S;  1VQM R;  3J7Z S;  3CCV R;  1KC8 S;  1K9M S;  1JJ2 Q;  1VQ9 R;  3PIO P;  5MLC U;  3G71 R;  3CC4 R;  3CMA R;  5HL7 P;  1Q82 S;  4WFB P;  3I56 R;  3J7Y T;  1VQK R;  1VQL R;  3CCM R;  3CD6 R;  3CME R;  3CPW Q;  1YI2 R;  1YHQ R;  1M90 S;  1NJI S;  3CCU R;  3CCL R;  3CF5 P;  3CCE R;  3OW2 Q;  1YJW R;  1Q86 S; 
#chains in the Genus database with same CATH topology
 2C43 A;  3PIP P;  4UY8 S;  1VQP R;  4U67 P;  3CC2 R;  5GAG T;  3CXC Q;  4DXE A;  1Q81 S;  5GAE T;  3QMN A;  4IO9 P;  2ZJR P;  3CCR R;  1YJ9 R;  5JVG P;  2WDS A;  1F80 A;  1VQ7 R;  3NFD A;  2WDO A;  2D0P A;  2QA4 R;  1YIT R;  2WAS A;  4IOA P;  3HQJ A;  5H1S U;  5DM7 P;  4WFA P;  1K8A S;  2OTJ R;  3DLL P;  3G4S R;  1BXE A;  1QVG Q;  1VQO R;  1VQ8 R;  1FTH A;  2BDD A;  2ZJQ P;  1S72 R;  1YIJ R;  1VQN R;  3I55 R;  5GAD T;  1NBW A;  3CCJ R;  3CCS R;  4IOC P;  2QEX R;  3CCQ R;  1K73 S;  5GAH T;  5JVH P;  2OTL R;  5CXD A;  2ZJP P;  1KQS Q;  3NE3 B;  2WAT A;  4WCE P;  1I4J A;  4HC6 A;  2QG8 A;  1KD1 S;  1FTF A;  1VQ6 R;  1VQ5 R;  1YJN R;  1Q7Y S;  1VQ4 R;  3NE9 A;  3H7Q A;  3G6E R;  2JCA A;  4WFN P;  1M1K S;  1QVF Q;  5DM6 P;  3HYK A;  1W2B Q;  3CC7 R;  4V19 W;  4WF9 P;  1N8R S;  1VQM R;  3J7Z S;  3CCV R;  1KC8 S;  1K9M S;  1F7L A;  1JJ2 Q;  3NE1 A;  2BYD A;  2CG5 A;  1VQ9 R;  5CMO A;  5MLC U;  3PIO P;  3G71 R;  3CC4 R;  2JBZ A;  2WAS B;  3CMA R;  5HL7 P;  4MRT A;  2D0O A;  3GWM A;  4JM7 A;  1Q82 S;  4WFB P;  3I56 R;  2WDY A;  3J7Y T;  1VQK R;  1QR0 A;  1VQL R;  3CCM R;  3CD6 R;  3CME R;  3CPW Q;  1YI2 R;  1YHQ R;  1F7T A;  1M90 S;  1NJI S;  3CCU R;  3CCL R;  3CF5 P;  3CCE R;  1FTE A;  3OW2 Q;  1YJW R;  1Q86 S; 
#chains in the Genus database with same CATH homology
 3PIP P;  4UY8 S;  1VQP R;  4U67 P;  3CC2 R;  5GAG T;  3CXC Q;  1Q81 S;  5GAE T;  4IO9 P;  2ZJR P;  3CCR R;  1YJ9 R;  5JVG P;  1VQ7 R;  2QA4 R;  1YIT R;  4IOA P;  5H1S U;  5DM7 P;  4WFA P;  1K8A S;  2OTJ R;  3DLL P;  3G4S R;  1BXE A;  1QVG Q;  1VQO R;  1VQ8 R;  2ZJQ P;  1S72 R;  1YIJ R;  1VQN R;  3I55 R;  5GAD T;  3CCJ R;  3CCS R;  4IOC P;  2QEX R;  3CCQ R;  1K73 S;  5GAH T;  5JVH P;  2OTL R;  2ZJP P;  1KQS Q;  4WCE P;  1I4J A;  1KD1 S;  1VQ6 R;  1VQ5 R;  1YJN R;  1Q7Y S;  1VQ4 R;  3G6E R;  4WFN P;  1M1K S;  1QVF Q;  5DM6 P;  1W2B Q;  3CC7 R;  4V19 W;  4WF9 P;  1N8R S;  1VQM R;  3J7Z S;  3CCV R;  1KC8 S;  1K9M S;  1JJ2 Q;  1VQ9 R;  3PIO P;  5MLC U;  3G71 R;  3CC4 R;  3CMA R;  5HL7 P;  1Q82 S;  4WFB P;  3I56 R;  3J7Y T;  1VQK R;  1VQL R;  3CCM R;  3CD6 R;  3CME R;  3CPW Q;  1YI2 R;  1YHQ R;  1M90 S;  1NJI S;  3CCU R;  3CCL R;  3CF5 P;  3CCE R;  3OW2 Q;  1YJW R;  1Q86 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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