1NJIS

Structure of chloramphenicol bound to the 50s ribosomal subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 36
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2002-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1njiS00
1VQ6R 3G6ER 5DM7P 1Q7YS 5GADT 1M1KS 3CCSR 1Q81S 4WFNP 1VQ9R 2OTLR 1Q82S 1VQ4R 3G71R 1W2BQ 3CC2R 5H1SU 3DLLP 3CMAR 3I55R 5GAET 4IO9P 1NJIS 5JVGP 3I56R 1VQLR 1S72R 2ZJRP 1K73S 1VQNR 1M90S 3PIPP 1JJ2Q 1YIJR 1K9MS 3CCER 2QA4R 1N8RS 3G4SR 4WF9P 4IOCP 3CCLR 3CCQR 1I4JA 1YJ9R 2QEXR 3J7ZS 5JVHP 1VQOR 3OW2Q 1VQ8R 5MLCU 1KC8S 1YJNR 3J7YT 4WFBP 1BXEA 1YI2R 5GAGT 3CC4R 3CC7R 1KD1S 3CD6R 3CCVR 5DM6P 1QVFQ 5HL7P 3CMER 1VQMR 1VQPR 3CCRR 3CF5P 4U67P 4IOAP 4V19W 3CCUR 3CCMR 4WCEP 3CPWQ 1Q86S 1YHQR 1K8AS 1YITR 4WFAP 3PIOP 1VQ5R 2ZJPP 1VQ7R 3CXCQ 2ZJQP 1VQKR 5GAHT 1QVGQ 1YJWR 2OTJR 1KQSQ 4UY8S 3CCJR
chains in the Genus database with same CATH superfamily
1VQ6R 3NFDA 1QR0A 2BYDA 3G6ER 5DM7P 1NBWA 3QMNA 1Q7YS 5GADT 1M1KS 4UY8S 2BDDA 3CCSR 1Q81S 4WFNP 1VQ9R 2OTLR 1Q82S 1VQ4R 3G71R 1W2BQ 3CC2R 5H1SU 3DLLP 3CMAR 3I55R 5GAET 4IO9P 1NJIS 2WATA 5JVGP 3I56R 4JM7A 1VQLR 1FTEA 1S72R 2ZJRP 2WASA 1K73S 2WDYA 2WASB 1VQNR 1M90S 2WDOA 3PIPP 1JJ2Q 1YIJR 1K9MS 3CCER 4DXEA 2QA4R 3NE3B 1N8RS 3GWMA 5CXDA 3G4SR 4WF9P 4IOCP 3CCLR 2JCAA 3CCQR 1I4JA 1YJ9R 2QEXR 3H7QA 3J7ZS 3HYKA 5JVHP 1VQOR 3OW2Q 2D0OA 1VQ8R 5MLCU 1KC8S 1YJNR 3J7YT 4WFBP 3NE1A 1BXEA 1FTHA 1YI2R 5GAGT 2D0PA 2CG5A 3CC4R 3CC7R 2JBZA 1KD1S 3CD6R 3CCVR 5DM6P 1QVFQ 5HL7P 3CMER 1VQMR 3HQJA 4HC6A 1VQPR 3CCRR 3CF5P 4U67P 4IOAP 4V19W 3CCUR 1FTFA 3CCMR 1F7TA 5CMOA 4WCEP 3CPWQ 1Q86S 2QG8A 1YHQR 1F80A 1K8AS 3NE9A 1F7LA 2WDSA 1YITR 4WFAP 3PIOP 4MRTA 1VQ5R 2ZJPP 1VQ7R 3CXCQ 2ZJQP 1VQKR 5GAHT 1QVGQ 1YJWR 2OTJR 1KQSQ 2C43A 3CCJR
chains in the Genus database with same CATH topology
1VQ6R 3G6ER 5DM7P 1Q7YS 5GADT 1M1KS 3CCSR 1Q81S 4WFNP 1VQ9R 2OTLR 1Q82S 1VQ4R 3G71R 1W2BQ 3CC2R 5H1SU 3DLLP 3CMAR 3I55R 5GAET 4IO9P 1NJIS 5JVGP 3I56R 1VQLR 1S72R 2ZJRP 1K73S 1VQNR 1M90S 3PIPP 1JJ2Q 1YIJR 1K9MS 3CCER 2QA4R 1N8RS 3G4SR 4WF9P 4IOCP 3CCLR 3CCQR 1I4JA 1YJ9R 2QEXR 3J7ZS 5JVHP 1VQOR 3OW2Q 1VQ8R 5MLCU 1KC8S 1YJNR 3J7YT 4WFBP 1BXEA 1YI2R 5GAGT 3CC4R 3CC7R 1KD1S 3CD6R 3CCVR 5DM6P 1QVFQ 5HL7P 3CMER 1VQMR 1VQPR 3CCRR 3CF5P 4U67P 4IOAP 4V19W 3CCUR 3CCMR 4WCEP 3CPWQ 1Q86S 1YHQR 1K8AS 1YITR 4WFAP 3PIOP 1VQ5R 2ZJPP 1VQ7R 3CXCQ 2ZJQP 1VQKR 5GAHT 1QVGQ 1YJWR 2OTJR 1KQSQ 4UY8S 3CCJR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ6 R;  3G6E R;  5DM7 P;  1Q7Y S;  5GAD T;  1M1K S;  3CCS R;  1Q81 S;  4WFN P;  1VQ9 R;  2OTL R;  1Q82 S;  1VQ4 R;  3G71 R;  1W2B Q;  3CC2 R;  5H1S U;  3DLL P;  3CMA R;  3I55 R;  5GAE T;  4IO9 P;  1NJI S;  5JVG P;  3I56 R;  1VQL R;  1S72 R;  2ZJR P;  1K73 S;  1VQN R;  1M90 S;  3PIP P;  1JJ2 Q;  1YIJ R;  1K9M S;  3CCE R;  2QA4 R;  1N8R S;  3G4S R;  4WF9 P;  4IOC P;  3CCL R;  3CCQ R;  1I4J A;  1YJ9 R;  2QEX R;  3J7Z S;  5JVH P;  1VQO R;  3OW2 Q;  1VQ8 R;  5MLC U;  1KC8 S;  1YJN R;  3J7Y T;  4WFB P;  1BXE A;  1YI2 R;  5GAG T;  3CC4 R;  3CC7 R;  1KD1 S;  3CD6 R;  3CCV R;  5DM6 P;  1QVF Q;  5HL7 P;  3CME R;  1VQM R;  1VQP R;  3CCR R;  3CF5 P;  4U67 P;  4IOA P;  4V19 W;  3CCU R;  3CCM R;  4WCE P;  3CPW Q;  1Q86 S;  1YHQ R;  1K8A S;  1YIT R;  4WFA P;  3PIO P;  1VQ5 R;  2ZJP P;  1VQ7 R;  3CXC Q;  2ZJQ P;  1VQK R;  5GAH T;  1QVG Q;  1YJW R;  2OTJ R;  1KQS Q;  4UY8 S;  3CCJ R; 
#chains in the Genus database with same CATH topology
 1VQ6 R;  3NFD A;  1QR0 A;  2BYD A;  3G6E R;  5DM7 P;  1NBW A;  3QMN A;  1Q7Y S;  5GAD T;  1M1K S;  4UY8 S;  2BDD A;  3CCS R;  1Q81 S;  4WFN P;  1VQ9 R;  2OTL R;  1Q82 S;  1VQ4 R;  3G71 R;  1W2B Q;  3CC2 R;  5H1S U;  3DLL P;  3CMA R;  3I55 R;  5GAE T;  4IO9 P;  1NJI S;  2WAT A;  5JVG P;  3I56 R;  4JM7 A;  1VQL R;  1FTE A;  1S72 R;  2ZJR P;  2WAS A;  1K73 S;  2WDY A;  2WAS B;  1VQN R;  1M90 S;  2WDO A;  3PIP P;  1JJ2 Q;  1YIJ R;  1K9M S;  3CCE R;  4DXE A;  2QA4 R;  3NE3 B;  1N8R S;  3GWM A;  5CXD A;  3G4S R;  4WF9 P;  4IOC P;  3CCL R;  2JCA A;  3CCQ R;  1I4J A;  1YJ9 R;  2QEX R;  3H7Q A;  3J7Z S;  3HYK A;  5JVH P;  1VQO R;  3OW2 Q;  2D0O A;  1VQ8 R;  5MLC U;  1KC8 S;  1YJN R;  3J7Y T;  4WFB P;  3NE1 A;  1BXE A;  1FTH A;  1YI2 R;  5GAG T;  2D0P A;  2CG5 A;  3CC4 R;  3CC7 R;  2JBZ A;  1KD1 S;  3CD6 R;  3CCV R;  5DM6 P;  1QVF Q;  5HL7 P;  3CME R;  1VQM R;  3HQJ A;  4HC6 A;  1VQP R;  3CCR R;  3CF5 P;  4U67 P;  4IOA P;  4V19 W;  3CCU R;  1FTF A;  3CCM R;  1F7T A;  5CMO A;  4WCE P;  3CPW Q;  1Q86 S;  2QG8 A;  1YHQ R;  1F80 A;  1K8A S;  3NE9 A;  1F7L A;  2WDS A;  1YIT R;  4WFA P;  3PIO P;  4MRT A;  1VQ5 R;  2ZJP P;  1VQ7 R;  3CXC Q;  2ZJQ P;  1VQK R;  5GAH T;  1QVG Q;  1YJW R;  2OTJ R;  1KQS Q;  2C43 A;  3CCJ R; 
#chains in the Genus database with same CATH homology
 1VQ6 R;  3G6E R;  5DM7 P;  1Q7Y S;  5GAD T;  1M1K S;  3CCS R;  1Q81 S;  4WFN P;  1VQ9 R;  2OTL R;  1Q82 S;  1VQ4 R;  3G71 R;  1W2B Q;  3CC2 R;  5H1S U;  3DLL P;  3CMA R;  3I55 R;  5GAE T;  4IO9 P;  1NJI S;  5JVG P;  3I56 R;  1VQL R;  1S72 R;  2ZJR P;  1K73 S;  1VQN R;  1M90 S;  3PIP P;  1JJ2 Q;  1YIJ R;  1K9M S;  3CCE R;  2QA4 R;  1N8R S;  3G4S R;  4WF9 P;  4IOC P;  3CCL R;  3CCQ R;  1I4J A;  1YJ9 R;  2QEX R;  3J7Z S;  5JVH P;  1VQO R;  3OW2 Q;  1VQ8 R;  5MLC U;  1KC8 S;  1YJN R;  3J7Y T;  4WFB P;  1BXE A;  1YI2 R;  5GAG T;  3CC4 R;  3CC7 R;  1KD1 S;  3CD6 R;  3CCV R;  5DM6 P;  1QVF Q;  5HL7 P;  3CME R;  1VQM R;  1VQP R;  3CCR R;  3CF5 P;  4U67 P;  4IOA P;  4V19 W;  3CCU R;  3CCM R;  4WCE P;  3CPW Q;  1Q86 S;  1YHQ R;  1K8A S;  1YIT R;  4WFA P;  3PIO P;  1VQ5 R;  2ZJP P;  1VQ7 R;  3CXC Q;  2ZJQ P;  1VQK R;  5GAH T;  1QVG Q;  1YJW R;  2OTJ R;  1KQS Q;  4UY8 S;  3CCJ R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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