1YHQR

Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yhqR00
1VQPR 3CCVR 1YJWR 3CCER 2ZJRP 1QVGQ 1VQOR 5GAET 1BXEA 3G4SR 5DM7P 4WF9P 1M1KS 3J7ZS 3PIPP 4IOCP 3CCJR 1K8AS 3I55R 4V19W 3CXCQ 4IO9P 1VQLR 3CCUR 1VQNR 1Q81S 4WFAP 5H1SU 1YHQR 1YIJR 2ZJPP 1K9MS 1VQ4R 1YITR 3CCLR 3CC7R 5GADT 1Q86S 1YJNR 1Q7YS 4UY8S 5HL7P 4WFBP 1QVFQ 1VQ8R 1KQSQ 3CD6R 3OW2Q 5MLCU 3CF5P 1S72R 1W2BQ 1K73S 3CPWQ 5GAGT 3PIOP 4WFNP 1YI2R 3CMER 3CCQR 3CCSR 1M90S 1VQ7R 3CC4R 1JJ2Q 2QEXR 3J7YT 1VQMR 5JVHP 3DLLP 3CC2R 4WCEP 1Q82S 3CMAR 1I4JA 2QA4R 1KD1S 1YJ9R 1KC8S 1VQKR 1VQ5R 3G71R 5JVGP 2OTLR 2ZJQP 3I56R 1VQ6R 4IOAP 1VQ9R 5DM6P 4U67P 1NJIS 3CCRR 3CCMR 3G6ER 5GAHT 2OTJR 1N8RS
chains in the Genus database with same CATH superfamily
1VQPR 3CCVR 1YJWR 1FTEA 1NBWA 3GWMA 3CCER 2ZJRP 1QVGQ 1VQOR 5GAET 1BXEA 2BYDA 3G4SR 5DM7P 4WF9P 1M1KS 3J7ZS 2JCAA 3H7QA 3PIPP 4IOCP 3CCJR 1K8AS 3I55R 4V19W 1F7TA 4JM7A 3NE3B 3CXCQ 4IO9P 3HYKA 1VQLR 3CCUR 1VQNR 3NFDA 4WFAP 1Q81S 5H1SU 2WATA 1YHQR 2WASA 1YIJR 2ZJPP 3NE9A 1K9MS 1VQ4R 1YITR 3CCLR 3CC7R 2WDOA 5GADT 1Q86S 1YJNR 1Q7YS 4UY8S 2D0PA 5HL7P 4WFBP 1QVFQ 1VQ8R 1KQSQ 3CD6R 3OW2Q 4DXEA 4HC6A 5CXDA 2WDSA 5MLCU 2WDYA 2QG8A 3CF5P 1S72R 1W2BQ 1K73S 3CPWQ 5GAGT 3PIOP 4WFNP 1YI2R 3CMER 1QR0A 2CG5A 3CCQR 3HQJA 2BDDA 3CCSR 1M90S 1F7LA 4MRTA 1VQ7R 2D0OA 3CC4R 1JJ2Q 2QEXR 3J7YT 2JBZA 1VQMR 5JVHP 3DLLP 2C43A 4WCEP 3CC2R 1Q82S 3CMAR 1I4JA 2WASB 2QA4R 1KD1S 3NE1A 1YJ9R 1KC8S 1VQKR 1FTFA 1VQ5R 3G71R 5JVGP 1F80A 2OTLR 2ZJQP 3I56R 5CMOA 1VQ6R 4IOAP 1VQ9R 5DM6P 4U67P 1NJIS 3QMNA 3CCRR 3CCMR 3G6ER 1FTHA 5GAHT 2OTJR 1N8RS
chains in the Genus database with same CATH topology
1VQPR 3CCVR 1YJWR 3CCER 2ZJRP 1QVGQ 1VQOR 5GAET 1BXEA 3G4SR 5DM7P 4WF9P 1M1KS 3J7ZS 3PIPP 4IOCP 3CCJR 1K8AS 3I55R 4V19W 3CXCQ 4IO9P 1VQLR 3CCUR 1VQNR 1Q81S 4WFAP 5H1SU 1YHQR 1YIJR 2ZJPP 1K9MS 1VQ4R 1YITR 3CCLR 3CC7R 5GADT 1Q86S 1YJNR 1Q7YS 4UY8S 5HL7P 4WFBP 1QVFQ 1VQ8R 1KQSQ 3CD6R 3OW2Q 5MLCU 3CF5P 1S72R 1W2BQ 1K73S 3CPWQ 5GAGT 3PIOP 4WFNP 1YI2R 3CMER 3CCQR 3CCSR 1M90S 1VQ7R 3CC4R 1JJ2Q 2QEXR 3J7YT 1VQMR 5JVHP 3DLLP 3CC2R 4WCEP 1Q82S 3CMAR 1I4JA 2QA4R 1KD1S 1YJ9R 1KC8S 1VQKR 1VQ5R 3G71R 5JVGP 2OTLR 2ZJQP 3I56R 1VQ6R 4IOAP 1VQ9R 5DM6P 4U67P 1NJIS 3CCRR 3CCMR 3G6ER 5GAHT 2OTJR 1N8RS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQP R;  3CCV R;  1YJW R;  3CCE R;  2ZJR P;  1QVG Q;  1VQO R;  5GAE T;  1BXE A;  3G4S R;  5DM7 P;  4WF9 P;  1M1K S;  3J7Z S;  3PIP P;  4IOC P;  3CCJ R;  1K8A S;  3I55 R;  4V19 W;  3CXC Q;  4IO9 P;  1VQL R;  3CCU R;  1VQN R;  1Q81 S;  4WFA P;  5H1S U;  1YHQ R;  1YIJ R;  2ZJP P;  1K9M S;  1VQ4 R;  1YIT R;  3CCL R;  3CC7 R;  5GAD T;  1Q86 S;  1YJN R;  1Q7Y S;  4UY8 S;  5HL7 P;  4WFB P;  1QVF Q;  1VQ8 R;  1KQS Q;  3CD6 R;  3OW2 Q;  5MLC U;  3CF5 P;  1S72 R;  1W2B Q;  1K73 S;  3CPW Q;  5GAG T;  3PIO P;  4WFN P;  1YI2 R;  3CME R;  3CCQ R;  3CCS R;  1M90 S;  1VQ7 R;  3CC4 R;  1JJ2 Q;  2QEX R;  3J7Y T;  1VQM R;  5JVH P;  3DLL P;  3CC2 R;  4WCE P;  1Q82 S;  3CMA R;  1I4J A;  2QA4 R;  1KD1 S;  1YJ9 R;  1KC8 S;  1VQK R;  1VQ5 R;  3G71 R;  5JVG P;  2OTL R;  2ZJQ P;  3I56 R;  1VQ6 R;  4IOA P;  1VQ9 R;  5DM6 P;  4U67 P;  1NJI S;  3CCR R;  3CCM R;  3G6E R;  5GAH T;  2OTJ R;  1N8R S; 
#chains in the Genus database with same CATH topology
 1VQP R;  3CCV R;  1YJW R;  1FTE A;  1NBW A;  3GWM A;  3CCE R;  2ZJR P;  1QVG Q;  1VQO R;  5GAE T;  1BXE A;  2BYD A;  3G4S R;  5DM7 P;  4WF9 P;  1M1K S;  3J7Z S;  2JCA A;  3H7Q A;  3PIP P;  4IOC P;  3CCJ R;  1K8A S;  3I55 R;  4V19 W;  1F7T A;  4JM7 A;  3NE3 B;  3CXC Q;  4IO9 P;  3HYK A;  1VQL R;  3CCU R;  1VQN R;  3NFD A;  4WFA P;  1Q81 S;  5H1S U;  2WAT A;  1YHQ R;  2WAS A;  1YIJ R;  2ZJP P;  3NE9 A;  1K9M S;  1VQ4 R;  1YIT R;  3CCL R;  3CC7 R;  2WDO A;  5GAD T;  1Q86 S;  1YJN R;  1Q7Y S;  4UY8 S;  2D0P A;  5HL7 P;  4WFB P;  1QVF Q;  1VQ8 R;  1KQS Q;  3CD6 R;  3OW2 Q;  4DXE A;  4HC6 A;  5CXD A;  2WDS A;  5MLC U;  2WDY A;  2QG8 A;  3CF5 P;  1S72 R;  1W2B Q;  1K73 S;  3CPW Q;  5GAG T;  3PIO P;  4WFN P;  1YI2 R;  3CME R;  1QR0 A;  2CG5 A;  3CCQ R;  3HQJ A;  2BDD A;  3CCS R;  1M90 S;  1F7L A;  4MRT A;  1VQ7 R;  2D0O A;  3CC4 R;  1JJ2 Q;  2QEX R;  3J7Y T;  2JBZ A;  1VQM R;  5JVH P;  3DLL P;  2C43 A;  4WCE P;  3CC2 R;  1Q82 S;  3CMA R;  1I4J A;  2WAS B;  2QA4 R;  1KD1 S;  3NE1 A;  1YJ9 R;  1KC8 S;  1VQK R;  1FTF A;  1VQ5 R;  3G71 R;  5JVG P;  1F80 A;  2OTL R;  2ZJQ P;  3I56 R;  5CMO A;  1VQ6 R;  4IOA P;  1VQ9 R;  5DM6 P;  4U67 P;  1NJI S;  3QMN A;  3CCR R;  3CCM R;  3G6E R;  1FTH A;  5GAH T;  2OTJ R;  1N8R S; 
#chains in the Genus database with same CATH homology
 1VQP R;  3CCV R;  1YJW R;  3CCE R;  2ZJR P;  1QVG Q;  1VQO R;  5GAE T;  1BXE A;  3G4S R;  5DM7 P;  4WF9 P;  1M1K S;  3J7Z S;  3PIP P;  4IOC P;  3CCJ R;  1K8A S;  3I55 R;  4V19 W;  3CXC Q;  4IO9 P;  1VQL R;  3CCU R;  1VQN R;  1Q81 S;  4WFA P;  5H1S U;  1YHQ R;  1YIJ R;  2ZJP P;  1K9M S;  1VQ4 R;  1YIT R;  3CCL R;  3CC7 R;  5GAD T;  1Q86 S;  1YJN R;  1Q7Y S;  4UY8 S;  5HL7 P;  4WFB P;  1QVF Q;  1VQ8 R;  1KQS Q;  3CD6 R;  3OW2 Q;  5MLC U;  3CF5 P;  1S72 R;  1W2B Q;  1K73 S;  3CPW Q;  5GAG T;  3PIO P;  4WFN P;  1YI2 R;  3CME R;  3CCQ R;  3CCS R;  1M90 S;  1VQ7 R;  3CC4 R;  1JJ2 Q;  2QEX R;  3J7Y T;  1VQM R;  5JVH P;  3DLL P;  3CC2 R;  4WCE P;  1Q82 S;  3CMA R;  1I4J A;  2QA4 R;  1KD1 S;  1YJ9 R;  1KC8 S;  1VQK R;  1VQ5 R;  3G71 R;  5JVG P;  2OTL R;  2ZJQ P;  3I56 R;  1VQ6 R;  4IOA P;  1VQ9 R;  5DM6 P;  4U67 P;  1NJI S;  3CCR R;  3CCM R;  3G6E R;  5GAH T;  2OTJ R;  1N8R S; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...