1YIJR

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 36
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yijR00
3CCUR 5JVHP 3CCQR 1YJ9R 4WFBP 1K73S 3PIOP 1S72R 1KQSQ 1YI2R 3J7ZS 1N8RS 2QEXR 3CMAR 2ZJQP 1VQPR 2ZJRP 1QVFQ 3I55R 1Q82S 2OTJR 3PIPP 4UY8S 3CC2R 1VQ7R 3CPWQ 1Q86S 1VQ9R 1YJNR 1W2BQ 5GAGT 4V19W 2ZJPP 3J7YT 5JVGP 1VQOR 3CCJR 1YITR 1YJWR 1M90S 3DLLP 3OW2Q 3CCSR 4WFAP 4WCEP 1VQMR 1K8AS 5MLCU 1VQLR 1M1KS 3CCER 3CXCQ 2QA4R 1VQ5R 3I56R 4IO9P 1YIJR 3CC7R 3G6ER 5GADT 4U67P 1BXEA 4WFNP 5DM7P 5HL7P 3CF5P 4WF9P 1K9MS 1QVGQ 3CCRR 1VQKR 3CMER 3G4SR 3CC4R 1YHQR 3CCMR 3CD6R 1NJIS 3CCLR 1Q81S 1KC8S 4IOCP 1KD1S 1I4JA 5DM6P 1VQ6R 1Q7YS 3G71R 5GAHT 1VQNR 1VQ4R 5GAET 3CCVR 4IOAP 1JJ2Q 5H1SU 1VQ8R 2OTLR
chains in the Genus database with same CATH superfamily
3CCUR 5JVHP 2WDSA 3HYKA 3CCQR 1NBWA 2WASA 1YJ9R 4WFBP 1K73S 3PIOP 1S72R 1KQSQ 2D0OA 1YI2R 3J7ZS 1N8RS 2QEXR 3CMAR 2ZJQP 1VQPR 2ZJRP 1QVFQ 3I55R 1Q82S 4MRTA 2OTJR 3NE9A 3PIPP 4UY8S 3CC2R 1VQ7R 3CPWQ 1Q86S 1VQ9R 1YJNR 1F80A 3NE1A 1W2BQ 5GAGT 4V19W 3HQJA 2D0PA 4JM7A 2WDOA 2ZJPP 2JBZA 3J7YT 5JVGP 1VQOR 1FTFA 3CCJR 1YITR 1YJWR 1M90S 1FTHA 3DLLP 1FTEA 3OW2Q 3CCSR 4WFAP 4WCEP 1VQMR 1K8AS 2BYDA 5MLCU 1VQLR 1M1KS 3CCER 2WATA 3CXCQ 2QA4R 1VQ5R 3I56R 4IO9P 1QR0A 1YIJR 3CC7R 3G6ER 5GADT 4U67P 1BXEA 4WFNP 5DM7P 2BDDA 5HL7P 3CF5P 4HC6A 3H7QA 4WF9P 4DXEA 1K9MS 1QVGQ 3CCRR 1VQKR 3CMER 3G4SR 3CC4R 1YHQR 2WASB 1F7LA 3CCMR 3CD6R 3QMNA 1NJIS 3GWMA 3CCLR 1Q81S 3NFDA 1F7TA 2JCAA 3NE3B 1KC8S 2C43A 2WDYA 4IOCP 1I4JA 1KD1S 5DM6P 1VQ6R 1Q7YS 3G71R 5GAHT 5CMOA 1VQNR 1VQ4R 5GAET 3CCVR 4IOAP 2QG8A 1JJ2Q 5H1SU 1VQ8R 5CXDA 2OTLR 2CG5A
chains in the Genus database with same CATH topology
3CCUR 5JVHP 3CCQR 1YJ9R 4WFBP 1K73S 3PIOP 1S72R 1KQSQ 1YI2R 3J7ZS 1N8RS 2QEXR 3CMAR 2ZJQP 1VQPR 2ZJRP 1QVFQ 3I55R 1Q82S 2OTJR 3PIPP 4UY8S 3CC2R 1VQ7R 3CPWQ 1Q86S 1VQ9R 1YJNR 1W2BQ 5GAGT 4V19W 2ZJPP 3J7YT 5JVGP 1VQOR 3CCJR 1YITR 1YJWR 1M90S 3DLLP 3OW2Q 3CCSR 4WFAP 4WCEP 1VQMR 1K8AS 5MLCU 1VQLR 1M1KS 3CCER 3CXCQ 2QA4R 1VQ5R 3I56R 4IO9P 1YIJR 3CC7R 3G6ER 5GADT 4U67P 1BXEA 4WFNP 5DM7P 5HL7P 3CF5P 4WF9P 1K9MS 1QVGQ 3CCRR 1VQKR 3CMER 3G4SR 3CC4R 1YHQR 3CCMR 3CD6R 1NJIS 3CCLR 1Q81S 1KC8S 4IOCP 1KD1S 1I4JA 5DM6P 1VQ6R 1Q7YS 3G71R 5GAHT 1VQNR 1VQ4R 5GAET 3CCVR 4IOAP 1JJ2Q 5H1SU 1VQ8R 2OTLR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCU R;  5JVH P;  3CCQ R;  1YJ9 R;  4WFB P;  1K73 S;  3PIO P;  1S72 R;  1KQS Q;  1YI2 R;  3J7Z S;  1N8R S;  2QEX R;  3CMA R;  2ZJQ P;  1VQP R;  2ZJR P;  1QVF Q;  3I55 R;  1Q82 S;  2OTJ R;  3PIP P;  4UY8 S;  3CC2 R;  1VQ7 R;  3CPW Q;  1Q86 S;  1VQ9 R;  1YJN R;  1W2B Q;  5GAG T;  4V19 W;  2ZJP P;  3J7Y T;  5JVG P;  1VQO R;  3CCJ R;  1YIT R;  1YJW R;  1M90 S;  3DLL P;  3OW2 Q;  3CCS R;  4WFA P;  4WCE P;  1VQM R;  1K8A S;  5MLC U;  1VQL R;  1M1K S;  3CCE R;  3CXC Q;  2QA4 R;  1VQ5 R;  3I56 R;  4IO9 P;  1YIJ R;  3CC7 R;  3G6E R;  5GAD T;  4U67 P;  1BXE A;  4WFN P;  5DM7 P;  5HL7 P;  3CF5 P;  4WF9 P;  1K9M S;  1QVG Q;  3CCR R;  1VQK R;  3CME R;  3G4S R;  3CC4 R;  1YHQ R;  3CCM R;  3CD6 R;  1NJI S;  3CCL R;  1Q81 S;  1KC8 S;  4IOC P;  1KD1 S;  1I4J A;  5DM6 P;  1VQ6 R;  1Q7Y S;  3G71 R;  5GAH T;  1VQN R;  1VQ4 R;  5GAE T;  3CCV R;  4IOA P;  1JJ2 Q;  5H1S U;  1VQ8 R;  2OTL R; 
#chains in the Genus database with same CATH topology
 3CCU R;  5JVH P;  2WDS A;  3HYK A;  3CCQ R;  1NBW A;  2WAS A;  1YJ9 R;  4WFB P;  1K73 S;  3PIO P;  1S72 R;  1KQS Q;  2D0O A;  1YI2 R;  3J7Z S;  1N8R S;  2QEX R;  3CMA R;  2ZJQ P;  1VQP R;  2ZJR P;  1QVF Q;  3I55 R;  1Q82 S;  4MRT A;  2OTJ R;  3NE9 A;  3PIP P;  4UY8 S;  3CC2 R;  1VQ7 R;  3CPW Q;  1Q86 S;  1VQ9 R;  1YJN R;  1F80 A;  3NE1 A;  1W2B Q;  5GAG T;  4V19 W;  3HQJ A;  2D0P A;  4JM7 A;  2WDO A;  2ZJP P;  2JBZ A;  3J7Y T;  5JVG P;  1VQO R;  1FTF A;  3CCJ R;  1YIT R;  1YJW R;  1M90 S;  1FTH A;  3DLL P;  1FTE A;  3OW2 Q;  3CCS R;  4WFA P;  4WCE P;  1VQM R;  1K8A S;  2BYD A;  5MLC U;  1VQL R;  1M1K S;  3CCE R;  2WAT A;  3CXC Q;  2QA4 R;  1VQ5 R;  3I56 R;  4IO9 P;  1QR0 A;  1YIJ R;  3CC7 R;  3G6E R;  5GAD T;  4U67 P;  1BXE A;  4WFN P;  5DM7 P;  2BDD A;  5HL7 P;  3CF5 P;  4HC6 A;  3H7Q A;  4WF9 P;  4DXE A;  1K9M S;  1QVG Q;  3CCR R;  1VQK R;  3CME R;  3G4S R;  3CC4 R;  1YHQ R;  2WAS B;  1F7L A;  3CCM R;  3CD6 R;  3QMN A;  1NJI S;  3GWM A;  3CCL R;  1Q81 S;  3NFD A;  1F7T A;  2JCA A;  3NE3 B;  1KC8 S;  2C43 A;  2WDY A;  4IOC P;  1I4J A;  1KD1 S;  5DM6 P;  1VQ6 R;  1Q7Y S;  3G71 R;  5GAH T;  5CMO A;  1VQN R;  1VQ4 R;  5GAE T;  3CCV R;  4IOA P;  2QG8 A;  1JJ2 Q;  5H1S U;  1VQ8 R;  5CXD A;  2OTL R;  2CG5 A; 
#chains in the Genus database with same CATH homology
 3CCU R;  5JVH P;  3CCQ R;  1YJ9 R;  4WFB P;  1K73 S;  3PIO P;  1S72 R;  1KQS Q;  1YI2 R;  3J7Z S;  1N8R S;  2QEX R;  3CMA R;  2ZJQ P;  1VQP R;  2ZJR P;  1QVF Q;  3I55 R;  1Q82 S;  2OTJ R;  3PIP P;  4UY8 S;  3CC2 R;  1VQ7 R;  3CPW Q;  1Q86 S;  1VQ9 R;  1YJN R;  1W2B Q;  5GAG T;  4V19 W;  2ZJP P;  3J7Y T;  5JVG P;  1VQO R;  3CCJ R;  1YIT R;  1YJW R;  1M90 S;  3DLL P;  3OW2 Q;  3CCS R;  4WFA P;  4WCE P;  1VQM R;  1K8A S;  5MLC U;  1VQL R;  1M1K S;  3CCE R;  3CXC Q;  2QA4 R;  1VQ5 R;  3I56 R;  4IO9 P;  1YIJ R;  3CC7 R;  3G6E R;  5GAD T;  4U67 P;  1BXE A;  4WFN P;  5DM7 P;  5HL7 P;  3CF5 P;  4WF9 P;  1K9M S;  1QVG Q;  3CCR R;  1VQK R;  3CME R;  3G4S R;  3CC4 R;  1YHQ R;  3CCM R;  3CD6 R;  1NJI S;  3CCL R;  1Q81 S;  1KC8 S;  4IOC P;  1KD1 S;  1I4J A;  5DM6 P;  1VQ6 R;  1Q7Y S;  3G71 R;  5GAH T;  1VQN R;  1VQ4 R;  5GAE T;  3CCV R;  4IOA P;  1JJ2 Q;  5H1S U;  1VQ8 R;  2OTL R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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