1YJNR

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 1yjnR00
2OTLR 5GAET 1BXEA 1YITR 5JVGP 3CC7R 1K8AS 5GAGT 1Q82S 1QVFQ 1VQ8R 3OW2Q 5JVHP 3CXCQ 1Q81S 3I55R 3CCJR 1Q7YS 5MLCU 1S72R 5GAHT 1KQSQ 4WF9P 1M90S 4WFAP 1JJ2Q 1VQ6R 3I56R 1VQNR 4U67P 1YIJR 1YJWR 1N8RS 1I4JA 3CPWQ 1VQMR 3CMER 1K9MS 1K73S 1VQLR 2OTJR 5GADT 3CD6R 1Q86S 3CCMR 3CC4R 1YHQR 1KD1S 2ZJPP 3CF5P 1YJ9R 3PIPP 4WCEP 3G6ER 4UY8S 3PIOP 1VQOR 1VQ9R 3CCRR 1QVGQ 4WFNP 1NJIS 2ZJRP 1VQ4R 3J7YT 3CCQR 3CC2R 3CMAR 2QA4R 1M1KS 2ZJQP 5DM6P 3G71R 4V19W 4IOAP 3G4SR 3J7ZS 4WFBP 5DM7P 5H1SU 1VQ7R 1W2BQ 3CCER 1VQKR 1VQ5R 3CCSR 2QEXR 5HL7P 1YJNR 3CCVR 3DLLP 1YI2R 4IOCP 1KC8S 3CCLR 1VQPR 4IO9P 3CCUR
chains in the Genus database with same CATH superfamily
2OTLR 4DXEA 5GAET 1BXEA 1YITR 3H7QA 5JVGP 4HC6A 3CC7R 1K8AS 5GAGT 1Q82S 1QVFQ 1VQ8R 3OW2Q 2WASB 1F80A 5JVHP 3CXCQ 5CXDA 1Q81S 3I55R 3CCJR 1Q7YS 5MLCU 3NE1A 5GAHT 1S72R 2D0OA 1KQSQ 4WF9P 2WDOA 1M90S 4WFAP 1JJ2Q 3HYKA 1VQ6R 3I56R 1VQNR 3QMNA 2WDSA 4U67P 1YIJR 1YJWR 1N8RS 1I4JA 4MRTA 3CPWQ 1VQMR 3CMER 1K9MS 2WASA 2C43A 1K73S 1VQLR 1F7LA 2OTJR 5GADT 3CD6R 1Q86S 2WDYA 3CCMR 2D0PA 3CC4R 1YHQR 3NFDA 1KD1S 2ZJPP 2BYDA 2JBZA 3GWMA 3CF5P 1YJ9R 1QR0A 3PIPP 4WCEP 3G6ER 4UY8S 2JCAA 3PIOP 1VQOR 3HQJA 1FTHA 5CMOA 1VQ9R 3CCRR 1QVGQ 4WFNP 1NJIS 1FTFA 2ZJRP 2BDDA 1VQ4R 3J7YT 2CG5A 3CCQR 3CC2R 3CMAR 1NBWA 2QA4R 1M1KS 2ZJQP 1F7TA 5DM6P 3G71R 4V19W 4IOAP 2QG8A 2WATA 3G4SR 3J7ZS 4WFBP 5H1SU 5DM7P 1VQ7R 1W2BQ 3CCER 1FTEA 1VQKR 1VQ5R 3CCSR 3NE3B 4JM7A 2QEXR 5HL7P 1YJNR 3NE9A 3CCVR 3DLLP 1YI2R 4IOCP 1KC8S 3CCLR 1VQPR 4IO9P 3CCUR
chains in the Genus database with same CATH topology
2OTLR 5GAET 1BXEA 1YITR 5JVGP 3CC7R 1K8AS 5GAGT 1Q82S 1QVFQ 1VQ8R 3OW2Q 5JVHP 3CXCQ 1Q81S 3I55R 3CCJR 1Q7YS 5MLCU 1S72R 5GAHT 1KQSQ 4WF9P 1M90S 4WFAP 1JJ2Q 1VQ6R 3I56R 1VQNR 4U67P 1YIJR 1YJWR 1N8RS 1I4JA 3CPWQ 1VQMR 3CMER 1K9MS 1K73S 1VQLR 2OTJR 5GADT 3CD6R 1Q86S 3CCMR 3CC4R 1YHQR 1KD1S 2ZJPP 3CF5P 1YJ9R 3PIPP 4WCEP 3G6ER 4UY8S 3PIOP 1VQOR 1VQ9R 3CCRR 1QVGQ 4WFNP 1NJIS 2ZJRP 1VQ4R 3J7YT 3CCQR 3CC2R 3CMAR 2QA4R 1M1KS 2ZJQP 5DM6P 3G71R 4V19W 4IOAP 3G4SR 3J7ZS 4WFBP 5DM7P 5H1SU 1VQ7R 1W2BQ 3CCER 1VQKR 1VQ5R 3CCSR 2QEXR 5HL7P 1YJNR 3CCVR 3DLLP 1YI2R 4IOCP 1KC8S 3CCLR 1VQPR 4IO9P 3CCUR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTL R;  5GAE T;  1BXE A;  1YIT R;  5JVG P;  3CC7 R;  1K8A S;  5GAG T;  1Q82 S;  1QVF Q;  1VQ8 R;  3OW2 Q;  5JVH P;  3CXC Q;  1Q81 S;  3I55 R;  3CCJ R;  1Q7Y S;  5MLC U;  1S72 R;  5GAH T;  1KQS Q;  4WF9 P;  1M90 S;  4WFA P;  1JJ2 Q;  1VQ6 R;  3I56 R;  1VQN R;  4U67 P;  1YIJ R;  1YJW R;  1N8R S;  1I4J A;  3CPW Q;  1VQM R;  3CME R;  1K9M S;  1K73 S;  1VQL R;  2OTJ R;  5GAD T;  3CD6 R;  1Q86 S;  3CCM R;  3CC4 R;  1YHQ R;  1KD1 S;  2ZJP P;  3CF5 P;  1YJ9 R;  3PIP P;  4WCE P;  3G6E R;  4UY8 S;  3PIO P;  1VQO R;  1VQ9 R;  3CCR R;  1QVG Q;  4WFN P;  1NJI S;  2ZJR P;  1VQ4 R;  3J7Y T;  3CCQ R;  3CC2 R;  3CMA R;  2QA4 R;  1M1K S;  2ZJQ P;  5DM6 P;  3G71 R;  4V19 W;  4IOA P;  3G4S R;  3J7Z S;  4WFB P;  5DM7 P;  5H1S U;  1VQ7 R;  1W2B Q;  3CCE R;  1VQK R;  1VQ5 R;  3CCS R;  2QEX R;  5HL7 P;  1YJN R;  3CCV R;  3DLL P;  1YI2 R;  4IOC P;  1KC8 S;  3CCL R;  1VQP R;  4IO9 P;  3CCU R; 
#chains in the Genus database with same CATH topology
 2OTL R;  4DXE A;  5GAE T;  1BXE A;  1YIT R;  3H7Q A;  5JVG P;  4HC6 A;  3CC7 R;  1K8A S;  5GAG T;  1Q82 S;  1QVF Q;  1VQ8 R;  3OW2 Q;  2WAS B;  1F80 A;  5JVH P;  3CXC Q;  5CXD A;  1Q81 S;  3I55 R;  3CCJ R;  1Q7Y S;  5MLC U;  3NE1 A;  5GAH T;  1S72 R;  2D0O A;  1KQS Q;  4WF9 P;  2WDO A;  1M90 S;  4WFA P;  1JJ2 Q;  3HYK A;  1VQ6 R;  3I56 R;  1VQN R;  3QMN A;  2WDS A;  4U67 P;  1YIJ R;  1YJW R;  1N8R S;  1I4J A;  4MRT A;  3CPW Q;  1VQM R;  3CME R;  1K9M S;  2WAS A;  2C43 A;  1K73 S;  1VQL R;  1F7L A;  2OTJ R;  5GAD T;  3CD6 R;  1Q86 S;  2WDY A;  3CCM R;  2D0P A;  3CC4 R;  1YHQ R;  3NFD A;  1KD1 S;  2ZJP P;  2BYD A;  2JBZ A;  3GWM A;  3CF5 P;  1YJ9 R;  1QR0 A;  3PIP P;  4WCE P;  3G6E R;  4UY8 S;  2JCA A;  3PIO P;  1VQO R;  3HQJ A;  1FTH A;  5CMO A;  1VQ9 R;  3CCR R;  1QVG Q;  4WFN P;  1NJI S;  1FTF A;  2ZJR P;  2BDD A;  1VQ4 R;  3J7Y T;  2CG5 A;  3CCQ R;  3CC2 R;  3CMA R;  1NBW A;  2QA4 R;  1M1K S;  2ZJQ P;  1F7T A;  5DM6 P;  3G71 R;  4V19 W;  4IOA P;  2QG8 A;  2WAT A;  3G4S R;  3J7Z S;  4WFB P;  5H1S U;  5DM7 P;  1VQ7 R;  1W2B Q;  3CCE R;  1FTE A;  1VQK R;  1VQ5 R;  3CCS R;  3NE3 B;  4JM7 A;  2QEX R;  5HL7 P;  1YJN R;  3NE9 A;  3CCV R;  3DLL P;  1YI2 R;  4IOC P;  1KC8 S;  3CCL R;  1VQP R;  4IO9 P;  3CCU R; 
#chains in the Genus database with same CATH homology
 2OTL R;  5GAE T;  1BXE A;  1YIT R;  5JVG P;  3CC7 R;  1K8A S;  5GAG T;  1Q82 S;  1QVF Q;  1VQ8 R;  3OW2 Q;  5JVH P;  3CXC Q;  1Q81 S;  3I55 R;  3CCJ R;  1Q7Y S;  5MLC U;  1S72 R;  5GAH T;  1KQS Q;  4WF9 P;  1M90 S;  4WFA P;  1JJ2 Q;  1VQ6 R;  3I56 R;  1VQN R;  4U67 P;  1YIJ R;  1YJW R;  1N8R S;  1I4J A;  3CPW Q;  1VQM R;  3CME R;  1K9M S;  1K73 S;  1VQL R;  2OTJ R;  5GAD T;  3CD6 R;  1Q86 S;  3CCM R;  3CC4 R;  1YHQ R;  1KD1 S;  2ZJP P;  3CF5 P;  1YJ9 R;  3PIP P;  4WCE P;  3G6E R;  4UY8 S;  3PIO P;  1VQO R;  1VQ9 R;  3CCR R;  1QVG Q;  4WFN P;  1NJI S;  2ZJR P;  1VQ4 R;  3J7Y T;  3CCQ R;  3CC2 R;  3CMA R;  2QA4 R;  1M1K S;  2ZJQ P;  5DM6 P;  3G71 R;  4V19 W;  4IOA P;  3G4S R;  3J7Z S;  4WFB P;  5DM7 P;  5H1S U;  1VQ7 R;  1W2B Q;  3CCE R;  1VQK R;  1VQ5 R;  3CCS R;  2QEX R;  5HL7 P;  1YJN R;  3CCV R;  3DLL P;  1YI2 R;  4IOC P;  1KC8 S;  3CCL R;  1VQP R;  4IO9 P;  3CCU R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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