2APHA

Crystal structure of human pgrp-ialphac in complex with muramyl pentapeptide
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
165
structure length
165
Chain Sequence
VCPNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHFKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Peptidoglycan recognition protein I-alpha
total genus 53
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 2aphA00
5DWFA 3CG9A 3NG4A 3QJ1A 1SK4A 2XZ4A 5E0BA 4X36A 3TRUA 1J3GA 2EAVA 4BXJA 3T2VA 2Y28A 1SXRA 4Q9EA 1OHTA 4BXDA 1Z6IA 4ORVA 3O4KA 2RKQA 3OGXA 4IVVA 3UMQA 3CORA 2L47A 3D2YA 2AR3A 2BH7A 4Q8SA 4BXEA 2CB3A 2XZ8A 4KNLA 2Y2EA 2F2LA 3QS0A 1SK3A 1LBAA 1AROL 1S2JA 3USXA 3D2ZA 4OLSA 4OPPA 4ZXMA 1YB0A 2EAXA 2Y2CA 2Y2BA 3HMBA 3QV4A 4Z8IA 3RT4A 3CXAA 2F2LX 4BJ4A 3RDRA 2APHA 3NW3A 1TWQA 4BPAA 3T39A 4FNNA 2Z9NA 4OUGA 3UMLA 3LATA 5CTVA 1YCKA 2R90A 3EP1A 4KNKA 3C2XA 5E0AA 3UILA 2Y2DA 4BOLA 2R2KA 2WKXA 4GF9A 3NNOA
chains in the Genus database with same CATH superfamily
5DWFA 3CG9A 3NG4A 3QJ1A 1SK4A 2XZ4A 5E0BA 4X36A 3TRUA 1J3GA 2EAVA 4BXJA 3T2VA 2Y28A 1SXRA 4Q9EA 1OHTA 4BXDA 1Z6IA 4ORVA 3O4KA 2RKQA 3OGXA 4IVVA 3UMQA 3CORA 2L47A 3D2YA 2AR3A 2BH7A 4Q8SA 4BXEA 2CB3A 2XZ8A 4KNLA 2Y2EA 2F2LA 3QS0A 1SK3A 1LBAA 1AROL 1S2JA 3USXA 3D2ZA 4OLSA 4OPPA 4ZXMA 1YB0A 2EAXA 2Y2CA 2Y2BA 3HMBA 3QV4A 4Z8IA 3RT4A 3CXAA 2F2LX 4BJ4A 3RDRA 2APHA 3NW3A 1TWQA 4BPAA 3T39A 4FNNA 2Z9NA 4OUGA 3UMLA 3LATA 5CTVA 1YCKA 2R90A 3EP1A 4KNKA 3C2XA 5E0AA 3UILA 2Y2DA 4BOLA 2R2KA 2WKXA 4GF9A 3NNOA
chains in the Genus database with same CATH topology
5DWFA 3CG9A 3NG4A 3QJ1A 1SK4A 2XZ4A 5E0BA 4X36A 3TRUA 1J3GA 2EAVA 4BXJA 3T2VA 2Y28A 1SXRA 4Q9EA 1OHTA 4BXDA 1Z6IA 4ORVA 3O4KA 2RKQA 3OGXA 4IVVA 3UMQA 3CORA 2L47A 3D2YA 2AR3A 2BH7A 4Q8SA 4BXEA 2CB3A 2XZ8A 4KNLA 2Y2EA 2F2LA 3QS0A 1SK3A 1LBAA 1AROL 1S2JA 3USXA 3D2ZA 4OLSA 4OPPA 4ZXMA 1YB0A 2EAXA 2Y2CA 2Y2BA 3HMBA 3QV4A 4Z8IA 3RT4A 3CXAA 2F2LX 4BJ4A 3RDRA 2APHA 3NW3A 1TWQA 4BPAA 3T39A 4FNNA 2Z9NA 4OUGA 3UMLA 3LATA 5CTVA 1YCKA 2R90A 3EP1A 4KNKA 3C2XA 5E0AA 3UILA 2Y2DA 4BOLA 2R2KA 2WKXA 4GF9A 3NNOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DWF A;  3CG9 A;  3NG4 A;  3QJ1 A;  1SK4 A;  2XZ4 A;  5E0B A;  4X36 A;  3TRU A;  1J3G A;  2EAV A;  4BXJ A;  3T2V A;  2Y28 A;  1SXR A;  4Q9E A;  1OHT A;  4BXD A;  1Z6I A;  4ORV A;  3O4K A;  2RKQ A;  3OGX A;  4IVV A;  3UMQ A;  3COR A;  2L47 A;  3D2Y A;  2AR3 A;  2BH7 A;  4Q8S A;  4BXE A;  2CB3 A;  2XZ8 A;  4KNL A;  2Y2E A;  2F2L A;  3QS0 A;  1SK3 A;  1LBA A;  1ARO L;  1S2J A;  3USX A;  3D2Z A;  4OLS A;  4OPP A;  4ZXM A;  1YB0 A;  2EAX A;  2Y2C A;  2Y2B A;  3HMB A;  3QV4 A;  4Z8I A;  3RT4 A;  3CXA A;  2F2L X;  4BJ4 A;  3RDR A;  2APH A;  3NW3 A;  1TWQ A;  4BPA A;  3T39 A;  4FNN A;  2Z9N A;  4OUG A;  3UML A;  3LAT A;  5CTV A;  1YCK A;  2R90 A;  3EP1 A;  4KNK A;  3C2X A;  5E0A A;  3UIL A;  2Y2D A;  4BOL A;  2R2K A;  2WKX A;  4GF9 A;  3NNO A; 
#chains in the Genus database with same CATH topology
 5DWF A;  3CG9 A;  3NG4 A;  3QJ1 A;  1SK4 A;  2XZ4 A;  5E0B A;  4X36 A;  3TRU A;  1J3G A;  2EAV A;  4BXJ A;  3T2V A;  2Y28 A;  1SXR A;  4Q9E A;  1OHT A;  4BXD A;  1Z6I A;  4ORV A;  3O4K A;  2RKQ A;  3OGX A;  4IVV A;  3UMQ A;  3COR A;  2L47 A;  3D2Y A;  2AR3 A;  2BH7 A;  4Q8S A;  4BXE A;  2CB3 A;  2XZ8 A;  4KNL A;  2Y2E A;  2F2L A;  3QS0 A;  1SK3 A;  1LBA A;  1ARO L;  1S2J A;  3USX A;  3D2Z A;  4OLS A;  4OPP A;  4ZXM A;  1YB0 A;  2EAX A;  2Y2C A;  2Y2B A;  3HMB A;  3QV4 A;  4Z8I A;  3RT4 A;  3CXA A;  2F2L X;  4BJ4 A;  3RDR A;  2APH A;  3NW3 A;  1TWQ A;  4BPA A;  3T39 A;  4FNN A;  2Z9N A;  4OUG A;  3UML A;  3LAT A;  5CTV A;  1YCK A;  2R90 A;  3EP1 A;  4KNK A;  3C2X A;  5E0A A;  3UIL A;  2Y2D A;  4BOL A;  2R2K A;  2WKX A;  4GF9 A;  3NNO A; 
#chains in the Genus database with same CATH homology
 5DWF A;  3CG9 A;  3NG4 A;  3QJ1 A;  1SK4 A;  2XZ4 A;  5E0B A;  4X36 A;  3TRU A;  1J3G A;  2EAV A;  4BXJ A;  3T2V A;  2Y28 A;  1SXR A;  4Q9E A;  1OHT A;  4BXD A;  1Z6I A;  4ORV A;  3O4K A;  2RKQ A;  3OGX A;  4IVV A;  3UMQ A;  3COR A;  2L47 A;  3D2Y A;  2AR3 A;  2BH7 A;  4Q8S A;  4BXE A;  2CB3 A;  2XZ8 A;  4KNL A;  2Y2E A;  2F2L A;  3QS0 A;  1SK3 A;  1LBA A;  1ARO L;  1S2J A;  3USX A;  3D2Z A;  4OLS A;  4OPP A;  4ZXM A;  1YB0 A;  2EAX A;  2Y2C A;  2Y2B A;  3HMB A;  3QV4 A;  4Z8I A;  3RT4 A;  3CXA A;  2F2L X;  4BJ4 A;  3RDR A;  2APH A;  3NW3 A;  1TWQ A;  4BPA A;  3T39 A;  4FNN A;  2Z9N A;  4OUG A;  3UML A;  3LAT A;  5CTV A;  1YCK A;  2R90 A;  3EP1 A;  4KNK A;  3C2X A;  5E0A A;  3UIL A;  2Y2D A;  4BOL A;  2R2K A;  2WKX A;  4GF9 A;  3NNO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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