2APHA

Crystal structure of human pgrp-ialphac in complex with muramyl pentapeptide
Total Genus 53
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
165
structure length
165
Chain Sequence
VCPNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHFKH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Peptidoglycan recognition protein I-alpha
total genus 53
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 2aphA00
3O4KA 3C2XA 3UILA 3T2VA 4OUGA 3CXAA 2XZ8A 2R90A 4BXEA 2EAXA 1S2JA 3T39A 4BXDA 1OHTA 2Y2CA 1YCKA 4OPPA 3TRUA 3UMQA 4Z8IA 5CTVA 4Q9EA 3RT4A 4BXJA 2Z9NA 3QJ1A 2AR3A 1Z6IA 3D2YA 3LATA 4KNKA 3EP1A 2CB3A 2F2LA 2L47A 3NG4A 4KNLA 3D2ZA 4FNNA 1SK4A 2Y2BA 1LBAA 3QS0A 4X36A 3CORA 4OLSA 4BJ4A 2Y2DA 2Y28A 4BOLA 2RKQA 4ORVA 3NW3A 1YB0A 3QV4A 5E0AA 2EAVA 2F2LX 2XZ4A 4Q8SA 4BPAA 2R2KA 3UMLA 3RDRA 3HMBA 1SK3A 4IVVA 1J3GA 3OGXA 1SXRA 3CG9A 5DWFA 4ZXMA 5E0BA 2BH7A 1TWQA 1AROL 2APHA 2Y2EA 3NNOA 3USXA 4GF9A 2WKXA
chains in the Genus database with same CATH superfamily
3O4KA 3C2XA 3UILA 3T2VA 4OUGA 3CXAA 2XZ8A 2R90A 4BXEA 2EAXA 1S2JA 3T39A 4BXDA 1OHTA 2Y2CA 1YCKA 4OPPA 3TRUA 3UMQA 4Z8IA 5CTVA 4Q9EA 3RT4A 4BXJA 2Z9NA 3QJ1A 2AR3A 1Z6IA 3D2YA 3LATA 4KNKA 3EP1A 2CB3A 2F2LA 2L47A 3NG4A 4KNLA 3D2ZA 4FNNA 1SK4A 2Y2BA 1LBAA 3QS0A 4X36A 3CORA 4OLSA 4BJ4A 2Y2DA 2Y28A 4BOLA 2RKQA 4ORVA 3NW3A 1YB0A 3QV4A 5E0AA 2EAVA 2F2LX 2XZ4A 4Q8SA 4BPAA 2R2KA 3UMLA 3RDRA 3HMBA 1SK3A 4IVVA 1J3GA 3OGXA 1SXRA 3CG9A 5DWFA 4ZXMA 5E0BA 2BH7A 1TWQA 1AROL 2APHA 2Y2EA 3NNOA 3USXA 4GF9A 2WKXA
chains in the Genus database with same CATH topology
3O4KA 3C2XA 3UILA 3T2VA 4OUGA 3CXAA 2XZ8A 2R90A 4BXEA 2EAXA 1S2JA 3T39A 4BXDA 1OHTA 2Y2CA 1YCKA 4OPPA 3TRUA 3UMQA 4Z8IA 5CTVA 4Q9EA 3RT4A 4BXJA 2Z9NA 3QJ1A 2AR3A 1Z6IA 3D2YA 3LATA 4KNKA 3EP1A 2CB3A 2F2LA 2L47A 3NG4A 4KNLA 3D2ZA 4FNNA 1SK4A 2Y2BA 1LBAA 3QS0A 4X36A 3CORA 4OLSA 4BJ4A 2Y2DA 2Y28A 4BOLA 2RKQA 4ORVA 3NW3A 1YB0A 3QV4A 5E0AA 2EAVA 2F2LX 2XZ4A 4Q8SA 4BPAA 2R2KA 3UMLA 3RDRA 3HMBA 1SK3A 4IVVA 1J3GA 3OGXA 1SXRA 3CG9A 5DWFA 4ZXMA 5E0BA 2BH7A 1TWQA 1AROL 2APHA 2Y2EA 3NNOA 3USXA 4GF9A 2WKXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O4K A;  3C2X A;  3UIL A;  3T2V A;  4OUG A;  3CXA A;  2XZ8 A;  2R90 A;  4BXE A;  2EAX A;  1S2J A;  3T39 A;  4BXD A;  1OHT A;  2Y2C A;  1YCK A;  4OPP A;  3TRU A;  3UMQ A;  4Z8I A;  5CTV A;  4Q9E A;  3RT4 A;  4BXJ A;  2Z9N A;  3QJ1 A;  2AR3 A;  1Z6I A;  3D2Y A;  3LAT A;  4KNK A;  3EP1 A;  2CB3 A;  2F2L A;  2L47 A;  3NG4 A;  4KNL A;  3D2Z A;  4FNN A;  1SK4 A;  2Y2B A;  1LBA A;  3QS0 A;  4X36 A;  3COR A;  4OLS A;  4BJ4 A;  2Y2D A;  2Y28 A;  4BOL A;  2RKQ A;  4ORV A;  3NW3 A;  1YB0 A;  3QV4 A;  5E0A A;  2EAV A;  2F2L X;  2XZ4 A;  4Q8S A;  4BPA A;  2R2K A;  3UML A;  3RDR A;  3HMB A;  1SK3 A;  4IVV A;  1J3G A;  3OGX A;  1SXR A;  3CG9 A;  5DWF A;  4ZXM A;  5E0B A;  2BH7 A;  1TWQ A;  1ARO L;  2APH A;  2Y2E A;  3NNO A;  3USX A;  4GF9 A;  2WKX A; 
#chains in the Genus database with same CATH topology
 3O4K A;  3C2X A;  3UIL A;  3T2V A;  4OUG A;  3CXA A;  2XZ8 A;  2R90 A;  4BXE A;  2EAX A;  1S2J A;  3T39 A;  4BXD A;  1OHT A;  2Y2C A;  1YCK A;  4OPP A;  3TRU A;  3UMQ A;  4Z8I A;  5CTV A;  4Q9E A;  3RT4 A;  4BXJ A;  2Z9N A;  3QJ1 A;  2AR3 A;  1Z6I A;  3D2Y A;  3LAT A;  4KNK A;  3EP1 A;  2CB3 A;  2F2L A;  2L47 A;  3NG4 A;  4KNL A;  3D2Z A;  4FNN A;  1SK4 A;  2Y2B A;  1LBA A;  3QS0 A;  4X36 A;  3COR A;  4OLS A;  4BJ4 A;  2Y2D A;  2Y28 A;  4BOL A;  2RKQ A;  4ORV A;  3NW3 A;  1YB0 A;  3QV4 A;  5E0A A;  2EAV A;  2F2L X;  2XZ4 A;  4Q8S A;  4BPA A;  2R2K A;  3UML A;  3RDR A;  3HMB A;  1SK3 A;  4IVV A;  1J3G A;  3OGX A;  1SXR A;  3CG9 A;  5DWF A;  4ZXM A;  5E0B A;  2BH7 A;  1TWQ A;  1ARO L;  2APH A;  2Y2E A;  3NNO A;  3USX A;  4GF9 A;  2WKX A; 
#chains in the Genus database with same CATH homology
 3O4K A;  3C2X A;  3UIL A;  3T2V A;  4OUG A;  3CXA A;  2XZ8 A;  2R90 A;  4BXE A;  2EAX A;  1S2J A;  3T39 A;  4BXD A;  1OHT A;  2Y2C A;  1YCK A;  4OPP A;  3TRU A;  3UMQ A;  4Z8I A;  5CTV A;  4Q9E A;  3RT4 A;  4BXJ A;  2Z9N A;  3QJ1 A;  2AR3 A;  1Z6I A;  3D2Y A;  3LAT A;  4KNK A;  3EP1 A;  2CB3 A;  2F2L A;  2L47 A;  3NG4 A;  4KNL A;  3D2Z A;  4FNN A;  1SK4 A;  2Y2B A;  1LBA A;  3QS0 A;  4X36 A;  3COR A;  4OLS A;  4BJ4 A;  2Y2D A;  2Y28 A;  4BOL A;  2RKQ A;  4ORV A;  3NW3 A;  1YB0 A;  3QV4 A;  5E0A A;  2EAV A;  2F2L X;  2XZ4 A;  4Q8S A;  4BPA A;  2R2K A;  3UML A;  3RDR A;  3HMB A;  1SK3 A;  4IVV A;  1J3G A;  3OGX A;  1SXR A;  3CG9 A;  5DWF A;  4ZXM A;  5E0B A;  2BH7 A;  1TWQ A;  1ARO L;  2APH A;  2Y2E A;  3NNO A;  3USX A;  4GF9 A;  2WKX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...