2EAXA

Crystal structure of human pgrp-ibetac in complex with glycosamyl muramyl pentapeptide
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
164
structure length
164
Chain Sequence
CPGIVPRSVWGARETHCPRMTLPAKYGIIIHTAGRTCNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAIYEGVGWNVQGSSTPGYDDIALGITFMGTFTGIPPNAAALEAAQDLIQCAMVKGYLTPNYLLVGHSDVARTLSPGQALYNIISTWPHFKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins
pubmed doi rcsb
molecule tags Peptidoglycan-binding protein
source organism Homo sapiens
molecule keywords Peptidoglycan recognition protein-I-beta
total genus 55
structure length 164
sequence length 164
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2007-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 2eaxA00
2EAVA 2R90A 3CG9A 3RT4A 4OUGA 4ZXMA 2AR3A 4BJ4A 3UMLA 2RKQA 1YCKA 4BXDA 3TRUA 2Y2CA 5DWFA 4Q8SA 4GF9A 3T39A 3CXAA 4BXJA 1Z6IA 2F2LX 4FNNA 3QJ1A 3NG4A 3RDRA 4BPAA 4KNKA 3LATA 1SK3A 2BH7A 2XZ8A 4X36A 2WKXA 1SK4A 3UILA 2EAXA 1J3GA 1YB0A 2APHA 1TWQA 1OHTA 4ORVA 3OGXA 3O4KA 3NW3A 2XZ4A 3EP1A 2L47A 1SXRA 2Y2BA 5CTVA 3D2YA 3T2VA 2Y2EA 3UMQA 1S2JA 3USXA 4BOLA 4Z8IA 2Y28A 3D2ZA 2CB3A 2Z9NA 4IVVA 1AROL 1LBAA 3NNOA 2R2KA 3QV4A 3C2XA 3CORA 2Y2DA 4OPPA 4KNLA 4Q9EA 3QS0A 5E0AA 4BXEA 2F2LA 3HMBA 5E0BA 4OLSA
chains in the Genus database with same CATH superfamily
2EAVA 2R90A 3CG9A 3RT4A 4OUGA 4ZXMA 2AR3A 4BJ4A 3UMLA 2RKQA 1YCKA 4BXDA 3TRUA 2Y2CA 5DWFA 4Q8SA 4GF9A 3T39A 3CXAA 4BXJA 1Z6IA 2F2LX 4FNNA 3QJ1A 3NG4A 3RDRA 4BPAA 4KNKA 3LATA 1SK3A 2BH7A 2XZ8A 4X36A 2WKXA 1SK4A 3UILA 2EAXA 1J3GA 1YB0A 2APHA 1TWQA 1OHTA 4ORVA 3OGXA 3O4KA 3NW3A 2XZ4A 3EP1A 2L47A 1SXRA 2Y2BA 5CTVA 3D2YA 3T2VA 2Y2EA 3UMQA 1S2JA 3USXA 4BOLA 4Z8IA 2Y28A 3D2ZA 2CB3A 2Z9NA 4IVVA 1AROL 1LBAA 3NNOA 2R2KA 3QV4A 3C2XA 3CORA 2Y2DA 4OPPA 4KNLA 4Q9EA 3QS0A 5E0AA 4BXEA 2F2LA 3HMBA 5E0BA 4OLSA
chains in the Genus database with same CATH topology
2EAVA 2R90A 3CG9A 3RT4A 4OUGA 4ZXMA 2AR3A 4BJ4A 3UMLA 2RKQA 1YCKA 4BXDA 3TRUA 2Y2CA 5DWFA 4Q8SA 4GF9A 3T39A 3CXAA 4BXJA 1Z6IA 2F2LX 4FNNA 3QJ1A 3NG4A 3RDRA 4BPAA 4KNKA 3LATA 1SK3A 2BH7A 2XZ8A 4X36A 2WKXA 1SK4A 3UILA 2EAXA 1J3GA 1YB0A 2APHA 1TWQA 1OHTA 4ORVA 3OGXA 3O4KA 3NW3A 2XZ4A 3EP1A 2L47A 1SXRA 2Y2BA 5CTVA 3D2YA 3T2VA 2Y2EA 3UMQA 1S2JA 3USXA 4BOLA 4Z8IA 2Y28A 3D2ZA 2CB3A 2Z9NA 4IVVA 1AROL 1LBAA 3NNOA 2R2KA 3QV4A 3C2XA 3CORA 2Y2DA 4OPPA 4KNLA 4Q9EA 3QS0A 5E0AA 4BXEA 2F2LA 3HMBA 5E0BA 4OLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EAV A;  2R90 A;  3CG9 A;  3RT4 A;  4OUG A;  4ZXM A;  2AR3 A;  4BJ4 A;  3UML A;  2RKQ A;  1YCK A;  4BXD A;  3TRU A;  2Y2C A;  5DWF A;  4Q8S A;  4GF9 A;  3T39 A;  3CXA A;  4BXJ A;  1Z6I A;  2F2L X;  4FNN A;  3QJ1 A;  3NG4 A;  3RDR A;  4BPA A;  4KNK A;  3LAT A;  1SK3 A;  2BH7 A;  2XZ8 A;  4X36 A;  2WKX A;  1SK4 A;  3UIL A;  2EAX A;  1J3G A;  1YB0 A;  2APH A;  1TWQ A;  1OHT A;  4ORV A;  3OGX A;  3O4K A;  3NW3 A;  2XZ4 A;  3EP1 A;  2L47 A;  1SXR A;  2Y2B A;  5CTV A;  3D2Y A;  3T2V A;  2Y2E A;  3UMQ A;  1S2J A;  3USX A;  4BOL A;  4Z8I A;  2Y28 A;  3D2Z A;  2CB3 A;  2Z9N A;  4IVV A;  1ARO L;  1LBA A;  3NNO A;  2R2K A;  3QV4 A;  3C2X A;  3COR A;  2Y2D A;  4OPP A;  4KNL A;  4Q9E A;  3QS0 A;  5E0A A;  4BXE A;  2F2L A;  3HMB A;  5E0B A;  4OLS A; 
#chains in the Genus database with same CATH topology
 2EAV A;  2R90 A;  3CG9 A;  3RT4 A;  4OUG A;  4ZXM A;  2AR3 A;  4BJ4 A;  3UML A;  2RKQ A;  1YCK A;  4BXD A;  3TRU A;  2Y2C A;  5DWF A;  4Q8S A;  4GF9 A;  3T39 A;  3CXA A;  4BXJ A;  1Z6I A;  2F2L X;  4FNN A;  3QJ1 A;  3NG4 A;  3RDR A;  4BPA A;  4KNK A;  3LAT A;  1SK3 A;  2BH7 A;  2XZ8 A;  4X36 A;  2WKX A;  1SK4 A;  3UIL A;  2EAX A;  1J3G A;  1YB0 A;  2APH A;  1TWQ A;  1OHT A;  4ORV A;  3OGX A;  3O4K A;  3NW3 A;  2XZ4 A;  3EP1 A;  2L47 A;  1SXR A;  2Y2B A;  5CTV A;  3D2Y A;  3T2V A;  2Y2E A;  3UMQ A;  1S2J A;  3USX A;  4BOL A;  4Z8I A;  2Y28 A;  3D2Z A;  2CB3 A;  2Z9N A;  4IVV A;  1ARO L;  1LBA A;  3NNO A;  2R2K A;  3QV4 A;  3C2X A;  3COR A;  2Y2D A;  4OPP A;  4KNL A;  4Q9E A;  3QS0 A;  5E0A A;  4BXE A;  2F2L A;  3HMB A;  5E0B A;  4OLS A; 
#chains in the Genus database with same CATH homology
 2EAV A;  2R90 A;  3CG9 A;  3RT4 A;  4OUG A;  4ZXM A;  2AR3 A;  4BJ4 A;  3UML A;  2RKQ A;  1YCK A;  4BXD A;  3TRU A;  2Y2C A;  5DWF A;  4Q8S A;  4GF9 A;  3T39 A;  3CXA A;  4BXJ A;  1Z6I A;  2F2L X;  4FNN A;  3QJ1 A;  3NG4 A;  3RDR A;  4BPA A;  4KNK A;  3LAT A;  1SK3 A;  2BH7 A;  2XZ8 A;  4X36 A;  2WKX A;  1SK4 A;  3UIL A;  2EAX A;  1J3G A;  1YB0 A;  2APH A;  1TWQ A;  1OHT A;  4ORV A;  3OGX A;  3O4K A;  3NW3 A;  2XZ4 A;  3EP1 A;  2L47 A;  1SXR A;  2Y2B A;  5CTV A;  3D2Y A;  3T2V A;  2Y2E A;  3UMQ A;  1S2J A;  3USX A;  4BOL A;  4Z8I A;  2Y28 A;  3D2Z A;  2CB3 A;  2Z9N A;  4IVV A;  1ARO L;  1LBA A;  3NNO A;  2R2K A;  3QV4 A;  3C2X A;  3COR A;  2Y2D A;  4OPP A;  4KNL A;  4Q9E A;  3QS0 A;  5E0A A;  4BXE A;  2F2L A;  3HMB A;  5E0B A;  4OLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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