2WFQA

Crystal structure of the n-terminal signalling domain of human dhh without calcium
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
164
structure length
164
Chain Sequence
LVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVKLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords DESERT HEDGEHOG PROTEIN N-PRODUCT
total genus 50
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2009-04-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wfqA00
4OX3A 4JIDA 1VHHA 1LBUA 4OAKA 2WFRA 5HNMA 3N1MB 1TZPA 2WG4A 2IBGE 4D0YA 3M1NA 1R44A 4MUTA 4MURA 3N1FA 1U10A 3N1RA 2WFQA 3K7GB 3N1PB 2WG3A 2VO9A 4NT9A 4OX5A 4OXDA 4MUSA 4F78A 3K7IB 3N1GA 3MXWA 3D1MA 2WFXA 3K7HB 4C4MA 4MPHA 3N1OA 3K7JB 3N1QA 4MUQA 4C4NA 3HO5H
chains in the Genus database with same CATH superfamily
4OX3A 3KXCC 1SZ7A 4JIDA 1VHHA 1LBUA 4OAKA 2WFRA 5HNMA 3NJCA 3N1MB 1TZPA 2J3RB 2WG4A 2IBGE 2J3WB 4D0YA 3M1NA 1R44A 4MUTA 2OSDA 3N1FA 4MURA 2J3WD 1U10A 3CUEB 3KXCA 3N1RA 2WFQA 3K7GB 3N1PB 2WG3A 2J3TA 2VO9A 3CUED 2CFHC 4NT9A 4MUSA 4OXDA 4OX5A 4F78A 3K7IB 3N1GA 3HO5H 2C0JA 3MXWA 2WFXA 3D1MA 2J3TB 1WC8A 2OSOA 3K7HB 4C4MA 2J3RA 2CFHA 1WC9A 3K7JB 3N1OA 3N1QA 4MPHA 4MUQA 4C4NA 2C0JB 2BJNA 2PWNA
chains in the Genus database with same CATH topology
4OX3A 4JIDA 1VHHA 1LBUA 4OAKA 2WFRA 5HNMA 3N1MB 1TZPA 2WG4A 2IBGE 4D0YA 3M1NA 1R44A 4MUTA 4MURA 3N1FA 1U10A 3N1RA 2WFQA 3K7GB 3N1PB 2WG3A 2VO9A 4NT9A 4OX5A 4OXDA 4MUSA 4F78A 3K7IB 3N1GA 3MXWA 3D1MA 2WFXA 3K7HB 4C4MA 4MPHA 3N1OA 3K7JB 3N1QA 4MUQA 4C4NA 3HO5H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OX3 A;  4JID A;  1VHH A;  1LBU A;  4OAK A;  2WFR A;  5HNM A;  3N1M B;  1TZP A;  2WG4 A;  2IBG E;  4D0Y A;  3M1N A;  1R44 A;  4MUT A;  4MUR A;  3N1F A;  1U10 A;  3N1R A;  2WFQ A;  3K7G B;  3N1P B;  2WG3 A;  2VO9 A;  4NT9 A;  4OX5 A;  4OXD A;  4MUS A;  4F78 A;  3K7I B;  3N1G A;  3MXW A;  3D1M A;  2WFX A;  3K7H B;  4C4M A;  4MPH A;  3N1O A;  3K7J B;  3N1Q A;  4MUQ A;  4C4N A;  3HO5 H; 
#chains in the Genus database with same CATH topology
 4OX3 A;  3KXC C;  1SZ7 A;  4JID A;  1VHH A;  1LBU A;  4OAK A;  2WFR A;  5HNM A;  3NJC A;  3N1M B;  1TZP A;  2J3R B;  2WG4 A;  2IBG E;  2J3W B;  4D0Y A;  3M1N A;  1R44 A;  4MUT A;  2OSD A;  3N1F A;  4MUR A;  2J3W D;  1U10 A;  3CUE B;  3KXC A;  3N1R A;  2WFQ A;  3K7G B;  3N1P B;  2WG3 A;  2J3T A;  2VO9 A;  3CUE D;  2CFH C;  4NT9 A;  4MUS A;  4OXD A;  4OX5 A;  4F78 A;  3K7I B;  3N1G A;  3HO5 H;  2C0J A;  3MXW A;  2WFX A;  3D1M A;  2J3T B;  1WC8 A;  2OSO A;  3K7H B;  4C4M A;  2J3R A;  2CFH A;  1WC9 A;  3K7J B;  3N1O A;  3N1Q A;  4MPH A;  4MUQ A;  4C4N A;  2C0J B;  2BJN A;  2PWN A; 
#chains in the Genus database with same CATH homology
 4OX3 A;  4JID A;  1VHH A;  1LBU A;  4OAK A;  2WFR A;  5HNM A;  3N1M B;  1TZP A;  2WG4 A;  2IBG E;  4D0Y A;  3M1N A;  1R44 A;  4MUT A;  4MUR A;  3N1F A;  1U10 A;  3N1R A;  2WFQ A;  3K7G B;  3N1P B;  2WG3 A;  2VO9 A;  4NT9 A;  4OX5 A;  4OXD A;  4MUS A;  4F78 A;  3K7I B;  3N1G A;  3MXW A;  3D1M A;  2WFX A;  3K7H B;  4C4M A;  4MPH A;  3N1O A;  3K7J B;  3N1Q A;  4MUQ A;  4C4N A;  3HO5 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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