2WFXA

Crystal structure of the complex between human hedgehog-interacting protein hip and sonic hedgehog in the presence of calcium
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
152
structure length
152
Chain Sequence
LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords SONIC HEDGEHOG PROTEIN N-PRODUCT
total genus 36
structure length 152
sequence length 152
ec nomenclature
pdb deposition date 2009-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wfxA00
3N1OA 4JIDA 3N1RA 4MUSA 3D1MA 4OX5A 2WG4A 2VO9A 4OAKA 2WG3A 4F78A 3N1MB 3HO5H 1TZPA 1R44A 3MXWA 4OXDA 4MUQA 1VHHA 5HNMA 4NT9A 4MUTA 3K7GB 3M1NA 4C4MA 3K7IB 3N1FA 2IBGE 4MPHA 4C4NA 4MURA 3N1QA 1LBUA 1U10A 3N1GA 4D0YA 2WFQA 3K7HB 3N1PB 4OX3A 3K7JB 2WFXA 2WFRA
chains in the Genus database with same CATH superfamily
3N1OA 4JIDA 3NJCA 3N1RA 2J3WB 3CUED 4MUSA 2C0JB 3D1MA 4OX5A 1SZ7A 2CFHA 2WG4A 2VO9A 2J3RB 2WG3A 4OAKA 4F78A 3N1MB 3HO5H 2OSDA 1WC8A 2J3TB 1TZPA 1R44A 3KXCC 2BJNA 2C0JA 3MXWA 2J3WD 4MUQA 4OXDA 2J3RA 1VHHA 5HNMA 4NT9A 4MUTA 3K7GB 3M1NA 1WC9A 2J3TA 3K7IB 4C4MA 3N1FA 2IBGE 2PWNA 4MPHA 4C4NA 4MURA 3N1QA 2CFHC 1LBUA 1U10A 3N1GA 4D0YA 2WFQA 3CUEB 3KXCA 3K7HB 2OSOA 3N1PB 4OX3A 3K7JB 2WFXA 2WFRA
chains in the Genus database with same CATH topology
3N1OA 4JIDA 3N1RA 4MUSA 3D1MA 4OX5A 2WG4A 2VO9A 4OAKA 2WG3A 4F78A 3N1MB 3HO5H 1TZPA 1R44A 3MXWA 4OXDA 4MUQA 1VHHA 5HNMA 4NT9A 4MUTA 3K7GB 3M1NA 4C4MA 3K7IB 3N1FA 2IBGE 4MPHA 4C4NA 4MURA 3N1QA 1LBUA 1U10A 3N1GA 4D0YA 2WFQA 3K7HB 3N1PB 4OX3A 3K7JB 2WFXA 2WFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N1O A;  4JID A;  3N1R A;  4MUS A;  3D1M A;  4OX5 A;  2WG4 A;  2VO9 A;  4OAK A;  2WG3 A;  4F78 A;  3N1M B;  3HO5 H;  1TZP A;  1R44 A;  3MXW A;  4OXD A;  4MUQ A;  1VHH A;  5HNM A;  4NT9 A;  4MUT A;  3K7G B;  3M1N A;  4C4M A;  3K7I B;  3N1F A;  2IBG E;  4MPH A;  4C4N A;  4MUR A;  3N1Q A;  1LBU A;  1U10 A;  3N1G A;  4D0Y A;  2WFQ A;  3K7H B;  3N1P B;  4OX3 A;  3K7J B;  2WFX A;  2WFR A; 
#chains in the Genus database with same CATH topology
 3N1O A;  4JID A;  3NJC A;  3N1R A;  2J3W B;  3CUE D;  4MUS A;  2C0J B;  3D1M A;  4OX5 A;  1SZ7 A;  2CFH A;  2WG4 A;  2VO9 A;  2J3R B;  2WG3 A;  4OAK A;  4F78 A;  3N1M B;  3HO5 H;  2OSD A;  1WC8 A;  2J3T B;  1TZP A;  1R44 A;  3KXC C;  2BJN A;  2C0J A;  3MXW A;  2J3W D;  4MUQ A;  4OXD A;  2J3R A;  1VHH A;  5HNM A;  4NT9 A;  4MUT A;  3K7G B;  3M1N A;  1WC9 A;  2J3T A;  3K7I B;  4C4M A;  3N1F A;  2IBG E;  2PWN A;  4MPH A;  4C4N A;  4MUR A;  3N1Q A;  2CFH C;  1LBU A;  1U10 A;  3N1G A;  4D0Y A;  2WFQ A;  3CUE B;  3KXC A;  3K7H B;  2OSO A;  3N1P B;  4OX3 A;  3K7J B;  2WFX A;  2WFR A; 
#chains in the Genus database with same CATH homology
 3N1O A;  4JID A;  3N1R A;  4MUS A;  3D1M A;  4OX5 A;  2WG4 A;  2VO9 A;  4OAK A;  2WG3 A;  4F78 A;  3N1M B;  3HO5 H;  1TZP A;  1R44 A;  3MXW A;  4OXD A;  4MUQ A;  1VHH A;  5HNM A;  4NT9 A;  4MUT A;  3K7G B;  3M1N A;  4C4M A;  3K7I B;  3N1F A;  2IBG E;  4MPH A;  4C4N A;  4MUR A;  3N1Q A;  1LBU A;  1U10 A;  3N1G A;  4D0Y A;  2WFQ A;  3K7H B;  3N1P B;  4OX3 A;  3K7J B;  2WFX A;  2WFR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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