2WFXA

Crystal structure of the complex between human hedgehog-interacting protein hip and sonic hedgehog in the presence of calcium
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
152
structure length
152
Chain Sequence
LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords SONIC HEDGEHOG PROTEIN N-PRODUCT
total genus 36
structure length 152
sequence length 152
ec nomenclature
pdb deposition date 2009-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wfxA00
3N1RA 3N1QA 4C4NA 2WFRA 2VO9A 4JIDA 4MUQA 3K7JB 4MURA 1TZPA 3M1NA 2WFXA 3MXWA 3N1FA 4F78A 1U10A 4OAKA 1R44A 4MUTA 4OX5A 3K7HB 4OXDA 1VHHA 4NT9A 3HO5H 4MUSA 3N1OA 2IBGE 2WG4A 2WFQA 3N1PB 4MPHA 3K7GB 2WG3A 3N1MB 3N1GA 1LBUA 3K7IB 3D1MA 4C4MA 5HNMA 4OX3A 4D0YA
chains in the Genus database with same CATH superfamily
3N1RA 3N1QA 2J3WD 2WFRA 3NJCA 2VO9A 4C4NA 1WC9A 2C0JB 3KXCC 4JIDA 4D0YA 4MUQA 3K7JB 4MURA 1TZPA 3M1NA 2WFXA 3MXWA 2C0JA 3CUEB 3N1FA 4F78A 1U10A 4OAKA 1R44A 2BJNA 4MUTA 4OX5A 2J3RB 3K7HB 4OXDA 1VHHA 2CFHA 4NT9A 3HO5H 2J3TB 1SZ7A 4MUSA 2J3WB 3CUED 2J3RA 3N1OA 2IBGE 2WG4A 2PWNA 2WFQA 3KXCA 3N1PB 3K7GB 4MPHA 2J3TA 2CFHC 2WG3A 3N1MB 3N1GA 1LBUA 3K7IB 3D1MA 4C4MA 1WC8A 5HNMA 2OSOA 4OX3A 2OSDA
chains in the Genus database with same CATH topology
3N1RA 3N1QA 4C4NA 2WFRA 2VO9A 4JIDA 4MUQA 3K7JB 4MURA 1TZPA 3M1NA 2WFXA 3MXWA 3N1FA 4F78A 1U10A 4OAKA 1R44A 4MUTA 4OX5A 3K7HB 4OXDA 1VHHA 4NT9A 3HO5H 4MUSA 3N1OA 2IBGE 2WG4A 2WFQA 3N1PB 4MPHA 3K7GB 2WG3A 3N1MB 3N1GA 1LBUA 3K7IB 3D1MA 4C4MA 5HNMA 4OX3A 4D0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N1R A;  3N1Q A;  4C4N A;  2WFR A;  2VO9 A;  4JID A;  4MUQ A;  3K7J B;  4MUR A;  1TZP A;  3M1N A;  2WFX A;  3MXW A;  3N1F A;  4F78 A;  1U10 A;  4OAK A;  1R44 A;  4MUT A;  4OX5 A;  3K7H B;  4OXD A;  1VHH A;  4NT9 A;  3HO5 H;  4MUS A;  3N1O A;  2IBG E;  2WG4 A;  2WFQ A;  3N1P B;  4MPH A;  3K7G B;  2WG3 A;  3N1M B;  3N1G A;  1LBU A;  3K7I B;  3D1M A;  4C4M A;  5HNM A;  4OX3 A;  4D0Y A; 
#chains in the Genus database with same CATH topology
 3N1R A;  3N1Q A;  2J3W D;  2WFR A;  3NJC A;  2VO9 A;  4C4N A;  1WC9 A;  2C0J B;  3KXC C;  4JID A;  4D0Y A;  4MUQ A;  3K7J B;  4MUR A;  1TZP A;  3M1N A;  2WFX A;  3MXW A;  2C0J A;  3CUE B;  3N1F A;  4F78 A;  1U10 A;  4OAK A;  1R44 A;  2BJN A;  4MUT A;  4OX5 A;  2J3R B;  3K7H B;  4OXD A;  1VHH A;  2CFH A;  4NT9 A;  3HO5 H;  2J3T B;  1SZ7 A;  4MUS A;  2J3W B;  3CUE D;  2J3R A;  3N1O A;  2IBG E;  2WG4 A;  2PWN A;  2WFQ A;  3KXC A;  3N1P B;  3K7G B;  4MPH A;  2J3T A;  2CFH C;  2WG3 A;  3N1M B;  3N1G A;  1LBU A;  3K7I B;  3D1M A;  4C4M A;  1WC8 A;  5HNM A;  2OSO A;  4OX3 A;  2OSD A; 
#chains in the Genus database with same CATH homology
 3N1R A;  3N1Q A;  4C4N A;  2WFR A;  2VO9 A;  4JID A;  4MUQ A;  3K7J B;  4MUR A;  1TZP A;  3M1N A;  2WFX A;  3MXW A;  3N1F A;  4F78 A;  1U10 A;  4OAK A;  1R44 A;  4MUT A;  4OX5 A;  3K7H B;  4OXD A;  1VHH A;  4NT9 A;  3HO5 H;  4MUS A;  3N1O A;  2IBG E;  2WG4 A;  2WFQ A;  3N1P B;  4MPH A;  3K7G B;  2WG3 A;  3N1M B;  3N1G A;  1LBU A;  3K7I B;  3D1M A;  4C4M A;  5HNM A;  4OX3 A;  4D0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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