2WG3A

Crystal structure of the complex between human hedgehog-interacting protein hip and desert hedgehog without calcium
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
160
structure length
155
Chain Sequence
ALVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords DESERT HEDGEHOG PROTEIN N-PRODUCT
total genus 46
structure length 155
sequence length 160
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wg3A00
3K7HB 3N1OA 3HO5H 1R44A 3N1RA 4OAKA 4F78A 1U10A 2VO9A 1TZPA 2WG3A 2WFXA 3N1GA 1LBUA 2IBGE 3N1QA 2WFRA 3K7JB 4D0YA 3N1PB 4C4NA 3N1FA 3M1NA 3D1MA 2WG4A 3MXWA 4MUTA 4MUQA 4JIDA 3K7GB 3N1MB 3K7IB 4OXDA 4OX3A 4C4MA 4MUSA 4MPHA 4OX5A 5HNMA 4NT9A 1VHHA 4MURA 2WFQA
chains in the Genus database with same CATH superfamily
2C0JA 3K7HB 2PWNA 3KXCC 3KXCA 3N1OA 3HO5H 1R44A 3N1RA 4OAKA 4F78A 1U10A 1WC8A 2VO9A 1TZPA 2WG3A 2WFXA 3N1GA 1LBUA 2OSDA 2IBGE 3N1QA 2WFRA 2BJNA 3K7JB 4D0YA 3N1PB 3CUED 4C4NA 3N1FA 3M1NA 1SZ7A 1WC9A 3D1MA 2J3TB 2J3RB 2J3WD 2WG4A 3MXWA 4MUTA 4MUQA 2C0JB 4JIDA 3K7GB 3N1MB 3K7IB 4OXDA 4OX3A 4C4MA 2CFHA 2OSOA 2CFHC 3CUEB 4MUSA 4MPHA 4OX5A 5HNMA 2J3WB 4NT9A 1VHHA 4MURA 2WFQA 2J3TA 2J3RA 3NJCA
chains in the Genus database with same CATH topology
3K7HB 3N1OA 3HO5H 1R44A 3N1RA 4OAKA 4F78A 1U10A 2VO9A 1TZPA 2WG3A 2WFXA 3N1GA 1LBUA 2IBGE 3N1QA 2WFRA 3K7JB 4D0YA 3N1PB 4C4NA 3N1FA 3M1NA 3D1MA 2WG4A 3MXWA 4MUTA 4MUQA 4JIDA 3K7GB 3N1MB 3K7IB 4OXDA 4OX3A 4C4MA 4MUSA 4MPHA 4OX5A 5HNMA 4NT9A 1VHHA 4MURA 2WFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K7H B;  3N1O A;  3HO5 H;  1R44 A;  3N1R A;  4OAK A;  4F78 A;  1U10 A;  2VO9 A;  1TZP A;  2WG3 A;  2WFX A;  3N1G A;  1LBU A;  2IBG E;  3N1Q A;  2WFR A;  3K7J B;  4D0Y A;  3N1P B;  4C4N A;  3N1F A;  3M1N A;  3D1M A;  2WG4 A;  3MXW A;  4MUT A;  4MUQ A;  4JID A;  3K7G B;  3N1M B;  3K7I B;  4OXD A;  4OX3 A;  4C4M A;  4MUS A;  4MPH A;  4OX5 A;  5HNM A;  4NT9 A;  1VHH A;  4MUR A;  2WFQ A; 
#chains in the Genus database with same CATH topology
 2C0J A;  3K7H B;  2PWN A;  3KXC C;  3KXC A;  3N1O A;  3HO5 H;  1R44 A;  3N1R A;  4OAK A;  4F78 A;  1U10 A;  1WC8 A;  2VO9 A;  1TZP A;  2WG3 A;  2WFX A;  3N1G A;  1LBU A;  2OSD A;  2IBG E;  3N1Q A;  2WFR A;  2BJN A;  3K7J B;  4D0Y A;  3N1P B;  3CUE D;  4C4N A;  3N1F A;  3M1N A;  1SZ7 A;  1WC9 A;  3D1M A;  2J3T B;  2J3R B;  2J3W D;  2WG4 A;  3MXW A;  4MUT A;  4MUQ A;  2C0J B;  4JID A;  3K7G B;  3N1M B;  3K7I B;  4OXD A;  4OX3 A;  4C4M A;  2CFH A;  2OSO A;  2CFH C;  3CUE B;  4MUS A;  4MPH A;  4OX5 A;  5HNM A;  2J3W B;  4NT9 A;  1VHH A;  4MUR A;  2WFQ A;  2J3T A;  2J3R A;  3NJC A; 
#chains in the Genus database with same CATH homology
 3K7H B;  3N1O A;  3HO5 H;  1R44 A;  3N1R A;  4OAK A;  4F78 A;  1U10 A;  2VO9 A;  1TZP A;  2WG3 A;  2WFX A;  3N1G A;  1LBU A;  2IBG E;  3N1Q A;  2WFR A;  3K7J B;  4D0Y A;  3N1P B;  4C4N A;  3N1F A;  3M1N A;  3D1M A;  2WG4 A;  3MXW A;  4MUT A;  4MUQ A;  4JID A;  3K7G B;  3N1M B;  3K7I B;  4OXD A;  4OX3 A;  4C4M A;  4MUS A;  4MPH A;  4OX5 A;  5HNM A;  4NT9 A;  1VHH A;  4MUR A;  2WFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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