2WG3A

Crystal structure of the complex between human hedgehog-interacting protein hip and desert hedgehog without calcium
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
160
structure length
155
Chain Sequence
ALVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords DESERT HEDGEHOG PROTEIN N-PRODUCT
total genus 46
structure length 155
sequence length 160
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wg3A00
2WG4A 3N1QA 1VHHA 1R44A 3N1GA 1LBUA 2WFRA 4MURA 3MXWA 4OAKA 4NT9A 4MUSA 3K7GB 2IBGE 3N1OA 1TZPA 4D0YA 3K7JB 3D1MA 4F78A 4OXDA 3K7IB 4OX5A 3N1FA 3M1NA 3N1PB 4MUTA 3N1MB 4JIDA 3HO5H 4MPHA 2WFQA 5HNMA 2WG3A 2WFXA 4C4NA 4MUQA 1U10A 3K7HB 3N1RA 4C4MA 2VO9A 4OX3A
chains in the Genus database with same CATH superfamily
2WG4A 3N1QA 1VHHA 1R44A 2J3WD 2C0JB 3N1GA 1LBUA 2WFRA 4MURA 2CFHA 3NJCA 3MXWA 4OAKA 4NT9A 4MUSA 2J3RA 3K7GB 3KXCA 2IBGE 3N1OA 1TZPA 4D0YA 2PWNA 3K7JB 3D1MA 1WC9A 4F78A 2J3TB 3CUEB 2BJNA 2CFHC 3CUED 4OXDA 3K7IB 4OX5A 3N1FA 3M1NA 3N1PB 3KXCC 2C0JA 2J3RB 4MUTA 1SZ7A 3N1MB 4JIDA 3HO5H 4MPHA 2WFQA 5HNMA 2WG3A 1WC8A 2OSOA 2WFXA 4C4NA 4MUQA 1U10A 3K7HB 3N1RA 4C4MA 2VO9A 2OSDA 4OX3A 2J3TA 2J3WB
chains in the Genus database with same CATH topology
2WG4A 3N1QA 1VHHA 1R44A 3N1GA 1LBUA 2WFRA 4MURA 3MXWA 4OAKA 4NT9A 4MUSA 3K7GB 2IBGE 3N1OA 1TZPA 4D0YA 3K7JB 3D1MA 4F78A 4OXDA 3K7IB 4OX5A 3N1FA 3M1NA 3N1PB 4MUTA 3N1MB 4JIDA 3HO5H 4MPHA 2WFQA 5HNMA 2WG3A 2WFXA 4C4NA 4MUQA 1U10A 3K7HB 3N1RA 4C4MA 2VO9A 4OX3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WG4 A;  3N1Q A;  1VHH A;  1R44 A;  3N1G A;  1LBU A;  2WFR A;  4MUR A;  3MXW A;  4OAK A;  4NT9 A;  4MUS A;  3K7G B;  2IBG E;  3N1O A;  1TZP A;  4D0Y A;  3K7J B;  3D1M A;  4F78 A;  4OXD A;  3K7I B;  4OX5 A;  3N1F A;  3M1N A;  3N1P B;  4MUT A;  3N1M B;  4JID A;  3HO5 H;  4MPH A;  2WFQ A;  5HNM A;  2WG3 A;  2WFX A;  4C4N A;  4MUQ A;  1U10 A;  3K7H B;  3N1R A;  4C4M A;  2VO9 A;  4OX3 A; 
#chains in the Genus database with same CATH topology
 2WG4 A;  3N1Q A;  1VHH A;  1R44 A;  2J3W D;  2C0J B;  3N1G A;  1LBU A;  2WFR A;  4MUR A;  2CFH A;  3NJC A;  3MXW A;  4OAK A;  4NT9 A;  4MUS A;  2J3R A;  3K7G B;  3KXC A;  2IBG E;  3N1O A;  1TZP A;  4D0Y A;  2PWN A;  3K7J B;  3D1M A;  1WC9 A;  4F78 A;  2J3T B;  3CUE B;  2BJN A;  2CFH C;  3CUE D;  4OXD A;  3K7I B;  4OX5 A;  3N1F A;  3M1N A;  3N1P B;  3KXC C;  2C0J A;  2J3R B;  4MUT A;  1SZ7 A;  3N1M B;  4JID A;  3HO5 H;  4MPH A;  2WFQ A;  5HNM A;  2WG3 A;  1WC8 A;  2OSO A;  2WFX A;  4C4N A;  4MUQ A;  1U10 A;  3K7H B;  3N1R A;  4C4M A;  2VO9 A;  2OSD A;  4OX3 A;  2J3T A;  2J3W B; 
#chains in the Genus database with same CATH homology
 2WG4 A;  3N1Q A;  1VHH A;  1R44 A;  3N1G A;  1LBU A;  2WFR A;  4MUR A;  3MXW A;  4OAK A;  4NT9 A;  4MUS A;  3K7G B;  2IBG E;  3N1O A;  1TZP A;  4D0Y A;  3K7J B;  3D1M A;  4F78 A;  4OXD A;  3K7I B;  4OX5 A;  3N1F A;  3M1N A;  3N1P B;  4MUT A;  3N1M B;  4JID A;  3HO5 H;  4MPH A;  2WFQ A;  5HNM A;  2WG3 A;  2WFX A;  4C4N A;  4MUQ A;  1U10 A;  3K7H B;  3N1R A;  4C4M A;  2VO9 A;  4OX3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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