2WG4A

Crystal structure of the complex between human hedgehog-interacting protein hip and sonic hedgehog without calcium
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
150
structure length
145
Chain Sequence
LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Mus musculus
publication title Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
pubmed doi rcsb
molecule keywords SONIC HEDGEHOG PROTEIN N-PRODUCT
total genus 40
structure length 145
sequence length 150
ec nomenclature
pdb deposition date 2009-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 2wg4A00
2IBGE 4OX5A 4OAKA 4OXDA 2WG3A 4F78A 4C4MA 2WFRA 4OX3A 4NT9A 3N1MB 1R44A 3M1NA 1TZPA 4MUSA 4D0YA 3N1FA 3K7IB 3D1MA 2WFXA 4MUTA 3N1QA 4MURA 2WFQA 1U10A 1VHHA 3MXWA 4JIDA 4C4NA 3K7GB 3N1GA 5HNMA 3N1OA 2VO9A 2WG4A 1LBUA 3HO5H 3K7HB 4MPHA 3N1PB 4MUQA 3N1RA 3K7JB
chains in the Genus database with same CATH superfamily
2C0JA 2IBGE 4OX5A 4OAKA 4OXDA 2WG3A 4F78A 2PWNA 4C4MA 2WFRA 4OX3A 4NT9A 2C0JB 3N1MB 1R44A 2CFHC 3M1NA 3CUEB 1TZPA 4MUSA 4D0YA 2J3RA 3N1FA 3K7IB 3D1MA 2WFXA 2OSDA 3KXCC 4MUTA 3NJCA 2J3RB 3N1QA 4MURA 1SZ7A 2WFQA 2J3WB 1U10A 1VHHA 3MXWA 2J3TA 4JIDA 3CUED 3K7GB 1WC9A 3N1OA 2VO9A 3N1GA 4C4NA 5HNMA 2WG4A 1LBUA 2CFHA 2J3TB 3HO5H 3K7HB 2OSOA 4MPHA 3KXCA 1WC8A 3N1PB 2BJNA 4MUQA 2J3WD 3N1RA 3K7JB
chains in the Genus database with same CATH topology
2IBGE 4OX5A 4OAKA 4OXDA 2WG3A 4F78A 4C4MA 2WFRA 4OX3A 4NT9A 3N1MB 1R44A 3M1NA 1TZPA 4MUSA 4D0YA 3N1FA 3K7IB 3D1MA 2WFXA 4MUTA 3N1QA 4MURA 2WFQA 1U10A 1VHHA 3MXWA 4JIDA 4C4NA 3K7GB 3N1GA 5HNMA 3N1OA 2VO9A 2WG4A 1LBUA 3HO5H 3K7HB 4MPHA 3N1PB 4MUQA 3N1RA 3K7JB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IBG E;  4OX5 A;  4OAK A;  4OXD A;  2WG3 A;  4F78 A;  4C4M A;  2WFR A;  4OX3 A;  4NT9 A;  3N1M B;  1R44 A;  3M1N A;  1TZP A;  4MUS A;  4D0Y A;  3N1F A;  3K7I B;  3D1M A;  2WFX A;  4MUT A;  3N1Q A;  4MUR A;  2WFQ A;  1U10 A;  1VHH A;  3MXW A;  4JID A;  4C4N A;  3K7G B;  3N1G A;  5HNM A;  3N1O A;  2VO9 A;  2WG4 A;  1LBU A;  3HO5 H;  3K7H B;  4MPH A;  3N1P B;  4MUQ A;  3N1R A;  3K7J B; 
#chains in the Genus database with same CATH topology
 2C0J A;  2IBG E;  4OX5 A;  4OAK A;  4OXD A;  2WG3 A;  4F78 A;  2PWN A;  4C4M A;  2WFR A;  4OX3 A;  4NT9 A;  2C0J B;  3N1M B;  1R44 A;  2CFH C;  3M1N A;  3CUE B;  1TZP A;  4MUS A;  4D0Y A;  2J3R A;  3N1F A;  3K7I B;  3D1M A;  2WFX A;  2OSD A;  3KXC C;  4MUT A;  3NJC A;  2J3R B;  3N1Q A;  4MUR A;  1SZ7 A;  2WFQ A;  2J3W B;  1U10 A;  1VHH A;  3MXW A;  2J3T A;  4JID A;  3CUE D;  3K7G B;  1WC9 A;  3N1O A;  2VO9 A;  3N1G A;  4C4N A;  5HNM A;  2WG4 A;  1LBU A;  2CFH A;  2J3T B;  3HO5 H;  3K7H B;  2OSO A;  4MPH A;  3KXC A;  1WC8 A;  3N1P B;  2BJN A;  4MUQ A;  2J3W D;  3N1R A;  3K7J B; 
#chains in the Genus database with same CATH homology
 2IBG E;  4OX5 A;  4OAK A;  4OXD A;  2WG3 A;  4F78 A;  4C4M A;  2WFR A;  4OX3 A;  4NT9 A;  3N1M B;  1R44 A;  3M1N A;  1TZP A;  4MUS A;  4D0Y A;  3N1F A;  3K7I B;  3D1M A;  2WFX A;  4MUT A;  3N1Q A;  4MUR A;  2WFQ A;  1U10 A;  1VHH A;  3MXW A;  4JID A;  4C4N A;  3K7G B;  3N1G A;  5HNM A;  3N1O A;  2VO9 A;  2WG4 A;  1LBU A;  3HO5 H;  3K7H B;  4MPH A;  3N1P B;  4MUQ A;  3N1R A;  3K7J B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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